Mwina inuyo kapena munthu wina m'banja mwanu mwapatsidwa mankhwala otchedwa Chlorpromazine ndi dokotala wanu. Mukamva dzinali, mungamve mantha pang'ono kapena kufuna kudziwa zambiri. Ndizachilendo kufunsa mafunso monga akuti, 'Kodi mankhwalawa ndi chiyani? Nchifukwa chiyani ndikupatsidwa awa?'. Popeza awa ndi mankhwala omwe nthawi zambiri amaperekedwa pa matenda amisala, pakhoza kukhala malingaliro osiyanasiyana olakwika pakati pa anthu. Chifukwa chake lero, tiyeni tikambirane za mankhwala a chlorpromazine awa m'njira yosavuta yomwe mungamvetse.
Kodi Chlorpromazine ndi chiyani kwenikweni?
Mwachidule, chlorpromazine ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana amisala. Ndi a gulu la mankhwala otchedwa antipsychotics . Dopamine ndi mankhwala omwe ali muubongo omwe amathandiza kuwongolera zinthu monga momwe timamvera komanso momwe timamvera. Mankhwalawa amagwira ntchito poyesa kuchuluka kwa dopamine iyi muubongo.
Komabe, mankhwalawa samangoperekedwa kwa matenda amisala okha. Madokotala amagwiritsa ntchito nthawi zina. Mwachitsanzo:
- Matenda amisala monga schizophrenia ndi bipolar disorder.
- Lamulirani nseru ndi kusanza.
- Kwa mavuto omwe akhala akuchitika kwa nthawi yayitali ndipo sangathe kuimitsidwa.
- Pa milandu ina ya matenda otchedwa porphyria.
- Masulani minofu yanu mukadwala tetanasi.
- Khazikitsani mtima wodwalayo musanachite opaleshoni kapena mayeso a zachipatala.
Zinthu zomwe muyenera kuuza dokotala wanu musanamwe mankhwalawa
Musanayambe kumwa mankhwalawa, ndikofunikira kwambiri kudziwitsa dokotala wanu za thanzi lanu lonse. Chifukwa mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwa anthu omwe ali ndi matenda enaake. Ngati muli ndi matenda aliwonse omwe atchulidwa pansipa, onetsetsani kuti mwauza dokotala wanu za vutoli.
| Mkhalidwe/chifukwa choyenera | Kufotokozera |
|---|---|
| Matenda omwe alipo | Chotupa cha muubongo, matenda amisala, matenda a shuga, glaucoma, kuvulala mutu, matenda a mtima, mbiri ya kugunda kwa mtima kosakhazikika, matenda a impso kapena chiwindi, kuthamanga kwa magazi, matenda a m'mapapo monga mphumu, matenda a Parkinson, matenda a prostate, khunyu. |
| Kusasangalala ndi thupi | Kuvuta kumeza chakudya, kuvutika kulamulira matumbo, kuvutika kukodza, kutsekeka kwa matumbo. |
| Mavuto okhudzana ndi magazi | Matenda monga kuchepa kwa maselo oyera m'magazi, maselo ofiira amagazi, kapena ma platelet. |
| Moyo ndi zizolowezi | Ngati mumakonda kumwa mowa pafupipafupi. |
| Matenda a ziwengo | Ngati muli ndi vuto la chlorpromazine, sulfites, mankhwala ena, zakudya, utoto kapena zotetezera. |
| Zochitika zapadera | Ngati muli ndi pakati, mukuyesera kutenga pakati, kapena mukuyamwitsa. |
Kodi mankhwalawa amaperekedwa bwanji?
Mankhwala awa si omwe mungapite nawo kunyumba. Chlorpromazine ndi jakisoni woperekedwa ndi dokotala kuchipatala kapena kuchipatala . Amaperekedwa m'thupi mwa jakisoni mu minofu kapena mumtsempha.
Kusamala kwambiri kuyenera kuperekedwa popereka mankhwalawa kwa ana. Ngakhale kuti nthawi zina amalimbikitsidwa kwa ana opitirira miyezi 6, ndikofunikira kutsatira njira zoyenera zodzitetezera.
Kuchuluka kwa mankhwala osokoneza bongo - Chofunika kwambiri!
Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, musawanyalanyaze. Pitani ku chipatala cha Emergency Unit (ETU) nthawi yomweyo. Ngati kuli kofunikira, mutha kuyimbira National Poisons Information Centre ku Colombo National Hospital kuti mupeze malangizo.
Mankhwala ena omwe angagwirizane ndi mankhwalawa
Ndikofunikira kwambiri kuuza dokotala wanu za mankhwala onse omwe mukumwa, chifukwa chlorpromazine imatha kuyanjana ndi mankhwala ena ambiri.
| Musamwe chlorpromazine ndi mankhwala awa. | |
|---|---|
| Cisapride | Pimozide |
| Dronedarone | Saquinavir |
| Metoclopramide | Thioridazine |
| Samalani kwambiri chifukwa mavuto angabukenso ndi izi. | |
| Mowa | Lithiamu |
| Mankhwala oletsa kuzizira, chifuwa, ndi chimfine | Mankhwala othamanga magazi |
| Mankhwala ochepetsa nkhawa, nkhawa, kapena tulo | Mankhwala Oletsa Kutsekeka kwa Mtima (Phenobarbital, Phenytoin) |
| Mankhwala a matenda a Parkinson (Levodopa) | Mankhwala osokoneza bongo |
| Mankhwala omwe amagwiritsidwa ntchito popangitsa munthu kugona panthawi ya opaleshoni | Mankhwala ochepetsa magazi monga Warfarin |
Mndandandawu sunathe, choncho onetsetsani kuti mwauza dokotala wanu za mankhwala aliwonse, mavitamini, kapena mankhwala achikhalidwe omwe mukumwa.
Zinthu zofunika kuziganizira mukamamwa mankhwala
Gulu lanu lachipatala lidzayang'anira bwino vuto lanu pamene mukulandira katemerayu, koma ndikofunikira kuti mudziwe izi.
Kugona ndi chizungulire
Mankhwalawa angakupangitseni kumva tulo, chizungulire, kapena kusawona bwino . Choncho pewani zinthu zoopsa monga kuyendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani. Samalani mukadzuka kapena kukhala pansi mwadzidzidzi , makamaka ngati ndinu okalamba. Izi zitha kuchepetsa mwayi wokomoka ndi kugwa. Kumwa mowa kungapangitse kuti tulo tiwonjezeke.
Kulamulira kutentha kwa thupi
Mankhwalawa angakhudze mphamvu ya thupi lanu yolamulira kutentha. Kupirira kwanu kuzizira kungachepe, ndipo kupirira kwanu kutentha kungachepe. Chifukwa chake, valani zovala zofunda masiku ozizira. Masiku otentha, chepetsani kukhudzana ndi dzuwa, chita masewera olimbitsa thupi, ndipo imwani madzi ambiri.
Kuzindikira kwa dzuwa
Mankhwalawa angapangitse khungu lanu kukhala losakhudzidwa ndi dzuwa. Choncho dzitetezeni ku dzuwa. Ngati mukuyenera kutuluka padzuwa, valani zovala zophimba thupi lanu ndipo gwiritsani ntchito mafuta oteteza ku dzuwa .
Pakamwa pouma
Kuuma pakamwa ndi zotsatira zoyipa zomwe zimachitika kawirikawiri chifukwa cha mankhwalawa. Izi zitha kuthetsedwa podya chingamu chopanda shuga, kuyamwa maswiti osatsekemera, komanso kumwa madzi ambiri.
Kodi zotsatirapo zake zingakhale zotani?
Monga mankhwala ena aliwonse, chlorpromazine ikhoza kukhala ndi zotsatirapo zake. Zina zimakhala zoopsa, zina zimakhala zofala. Ndikofunikira kudziwa izi.
| Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala wanu kapena kuchipatala nthawi yomweyo | |
|---|---|
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa nkhope, milomo, lilime kapena pakhosi. |
| Matenda a Malignant a Neuroleptic | Kutentha thupi kwambiri mwadzidzidzi, kuuma kwa minofu, thukuta kwambiri, kugunda kwa mtima mofulumira kapena kosakhazikika, kusokonezeka maganizo. |
| Zizindikiro za EPS (Zizindikiro za Extrapyramidal) | Kusuntha kosalamulirika kwa ziwalo za thupi (makamaka nkhope, pakamwa), kuuma kwa minofu, kunjenjemera, kutayika kwa mphamvu, komanso kusakhazikika. |
| Kuwonongeka kwa chiwindi | Kupweteka m'mimba yakumanja, kusowa chilakolako cha chakudya, nseru, khungu kapena maso kukhala achikasu, mkodzo wakuda wachikasu/bulauni, ndi ndowe zowala. |
| Zizindikiro zina zazikulu | Zizindikiro za matenda (malungo, kuzizira, chifuwa, pakhosi), kuthamanga kwa magazi (chizungulire, kukomoka). |
| Zinthu zomwe nthawi zambiri sizili zazikulu, koma ziyenera kufotokozedwa kwa dokotala ngati zikupitirira | |
| Kudzimbidwa | Pakamwa pouma |
| Kugona tulo | Kulemera |
| Chizungulire | |
Ngati mukukumana ndi zizindikiro zina zachilendo zomwe sizinatchulidwe pamndandandawu, lankhulani ndi dokotala wanu za zizindikirozo.
Uthenga Wopita Nawo Kunyumba
- Chlorpromazine ndi katemera amene amaperekedwa kuchipatala kapena ku chipatala kokha motsogozedwa ndi dokotala.
- Onetsetsani kuti mwauza dokotala wanu za mankhwala ena onse omwe mukumwa, matenda ena aliwonse omwe muli nawo, komanso ziwengo zilizonse zomwe muli nazo.
- Samalani mukamachita ntchito zomwe zimafuna kusamala, monga kuyendetsa galimoto, chifukwa kugona ndi chizungulire zimatha kuchitika mukamamwa mankhwala. Pewani kumwa mowa.
- Ngati mukukumana ndi mavuto aakulu monga kutentha thupi kwambiri, kuuma kwa minofu, kuyenda kosalamulirika kwa thupi, kapena kusintha kwa khungu kukhala lachikasu, funsani upangiri wa dokotala nthawi yomweyo.
- Ngati muli ndi nkhawa kapena mantha okhudza mankhwalawa, lankhulani ndi dokotala wanu za izi momasuka.
👩🏽⚕️ Mafunso ena (Mafunso Ofunsidwa Kawirikawiri)
💬 Jekeseni ya Chlorpromazine / Thorazine ndi mankhwala amphamvu kwambiri omwe amagwiritsidwa ntchito pochiza matenda ati?
Iyi si mankhwala wamba! Iyi ndi jakisoni wa mankhwala akale komanso amphamvu kwambiri (Antipsychotic Anti-M'badwo Woyamba) omwe amagwiritsidwa ntchito nthawi yomweyo kutonthoza wodwalayo ndikumugonetsa tulo tatikulu (kugona tulo tofa nato) ngati ali ndi 'misala yamaganizo' (Severe Psychosis/Agitation) yoyambitsidwa ndi schizophrenia, bipolar disorder, ndi mankhwala osokoneza bongo, pamene wodwalayo akuvutika maganizo mosalekeza, ndipo ali pachiwopsezo chachikulu chovulaza ena kapena iye mwini.
💬 Mukakuwa/kufuula ngati wamisala, kodi jakisoni uyu (Chlorpromazine) umathandiza bwanji ubongo wanu kuchira/kugona?
Zinthu zachilendo zotere zimaoneka/zimasokoneza kwambiri pamene mankhwala a 'Dopamine (Dopamine / D2)' muubongo achuluka! Katemerayu amatseka/kutseka kwathunthu ndi kutseka 'Dopamine receptors' zonse muubongo (Dopamine antagonist). Kuphatikiza apo, amazimitsanso makina omwe ali mu magawo a 'Histamine (H1)' ndi 'Adrenaline (Alpha-1)', kotero wodwalayo amakhala chete ndikukhala chete/kugona pakatha mphindi zochepa.
💬 Kodi ndi zotsatirapo ziti zomwe zingaphe (Machenjezo a Black Box) za katemera woopsa uyu (Thorazine)?
Choopsa chachikulu ndichakuti ngati izi ziperekedwa kwa okalamba omwe ali ndi matenda a dementia (dementia-related psychosis), amatha kusiya kupuma mwadzidzidzi ndikufa (Increased mortality)! Chinthu china choopsa kwambiri ndichakuti izi zingayambitse wodwalayo kugwa mu coma chifukwa cha 'Fatal Hypotension / Orthostatic'. Komanso, matenda oopsa a mitsempha omwe amachititsa kuti zikhale zosatheka kukhala chete, zomwe zimapangitsa kuti miyendo igwedezeke ngati yamisala komanso khosi/maso kusuntha (Extrapyramidal Symptoms / EPS / Tardive Dyskinesia) zitha kuchitika.
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