Kodi inu kapena mwana wanu mumakhala ndi ludzu nthawi zonse? Ndipo kodi mumakodza pafupipafupi? Mwina mwana wanu amanyowetsa bedi usiku. Pazochitika zotere, dokotala wanu angakulembereni piritsi lotchedwa 'Desmopressin'. Popeza mankhwalawa amagwiritsidwa ntchito kawirikawiri, ndipo popeza muyenera kusamala kwambiri mukamagwiritsa ntchito, lero tikambirana za piritsi la Desmopressin m'mawu osavuta.
Kodi Desmopressin ndi chiyani?
Mwachidule, Desmopressin ndi mahomoni opangidwa mu labu omwe ali ofanana ndi mahomoni otchedwa 'Vasopressin' omwe thupi lathu limapanga mwachibadwa. Mahomoni otchedwa Vasopressin m'thupi lathu amatumiza uthenga kuchokera ku ubongo kupita ku impso, kulamulira kuchuluka kwa madzi omwe amatuluka m'thupi ngati mkodzo. Chifukwa chake, piritsi la Desmopressin ili limachita chimodzimodzi.
Ntchito yake yayikulu ndikulamulira kuchuluka kwa mkodzo wotuluka ndi impso. Izi zikutanthauza kuti, imachepetsa kutaya madzi kosafunikira m'thupi ndipo imathandiza kuti thupi likhale ndi madzi okwanira. Ku Sri Lanka, mutha kuwona mankhwalawa pansi pa dzina lodziwika bwino la DDAVP.
Kodi ntchito za mankhwalawa ndi ziti?
Madokotala nthawi zambiri amapereka mankhwalawa pazochitika zingapo.
- Matenda a shuga a Central Diabetes Insipidus: Uwu ndi matenda omwe ubongo umatulutsa mahomoni ochepa a Vasopressin. Zotsatira zake, munthu amayamba kukodza kwambiri komanso kumva ludzu kwambiri. Desmopressin ndi yothandiza kwambiri poletsa vutoli.
- Kunyowetsa pabedi / Kutsegula m'mimba usiku: Madokotala amalimbikitsa mankhwalawa pa vutoli, makamaka kwa ana opitirira zaka 4. Amathandiza kuchepetsa kuchuluka kwa mkodzo womwe umatulutsa usiku ndikuletsa mwana kunyowetsa pabedi.
- Pambuyo pa kuvulala mutu kapena opaleshoni: Pambuyo pa kuvulala mutu kwambiri kapena opaleshoni ina ya ubongo, ntchito ya vasopressin ya hormone ikhoza kusokonekera kwakanthawi. Imagwiritsidwanso ntchito poletsa kukodza kwambiri panthawi zotere.
Zinthu zomwe muyenera kuuza dokotala wanu musanamwe mankhwala
Musanapereke mankhwala a Desmopressin, ndikofunikira kwambiri kudziwitsa dokotala wanu za mbiri yonse ya thanzi lanu, makamaka ngati muli ndi vuto lililonse mwa izi.
- Ngati munali ndi magazi oundana kale
- Ngati muli ndi vuto ngati Cystic Fibrosis
- Ngati muli ndi matenda a mtima kapena kuthamanga kwa magazi
- Ngati muli ndi matenda amtundu uliwonse a impso
- Ngati mwapezekapo kale ndi sodium yochepa m'magazi (izi ndizofunikira kwambiri)
- Ngati muli ndi vuto la Desmopressin, Vasopressin kapena mankhwala ena aliwonse, chakudya, kapena utoto
- Ngati muli ndi pakati kapena mukufuna kutenga mimba
- Ngati mayi akuyamwitsa mwana wake
Kutengera ndi izi, dokotala adzasankha ngati mankhwalawa ndi oyenera kwa inu kapena ayi komanso mlingo woti mupereke.
Kodi ndimagwiritsa ntchito bwanji mankhwalawa molondola?
Ndikofunikira kwambiri kudziwa bwino momwe mungagwiritsire ntchito mankhwalawa.
- Piritsi ili liyenera kumwedwa ndi kapu ya madzi.
- Ndikofunikira kwambiri kumwa mankhwala anu monga momwe dokotala wanu wanenera. Ngati mumwa kamodzi patsiku, imwani nthawi yomweyo tsiku lililonse (nthawi zambiri musanagone usiku).
- Musamwe mowa wochuluka kuposa momwe dokotala wanenera.
- Popereka mankhwala awa kwa ana: Popereka mankhwala awa kwa ana, malangizo a dokotala wa ana ayenera kutsatiridwa bwino lomwe.
- Ngati mwamwa mankhwala ochulukirapo mwangozi: Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo mwangozi, funsani nthawi yomweyo ku National Poisons Information Centre ku Colombo National Hospital. Kapena pitani ku Emergency Department (ETU) ya chipatala chapafupi.
Mankhwalawa aperekedwa kwa inu nokha. Musapatse wina aliyense, ngakhale atakhala ndi zizindikiro zomwezo zomwe muli nazo. Zingakhale zoopsa.
Kodi mungachite chiyani ngati mwaphonya mlingo wa mankhwala?
Ngati mwaiwala kumwa mlingo, imwani mwamsanga mukangokumbukira. Koma ngati nthawi yanu yotsatira yayandikira, dumphani mlingo womwe mwaphonya ndi kumwa mlingo wotsatira panthawi yomwe mwakonza. Musamwe mlingo wowirikiza kawiri.
Zinthu zofunika kusamala kwambiri mukamamwa mankhwala
Ichi ndi gawo lofunika kwambiri. Muyenera kusamala kwambiri ndi zinthu zina za moyo wanu mukamamwa mankhwalawa.
Kumwa Madzi - Chisamaliro Chachikulu!
Ichi ndiye chinthu chofunika kwambiri . Desmopressin imapangitsa kuti madzi azisungidwa m'thupi, choncho muyenera kusamala kwambiri ndi kuchuluka kwa madzi omwe mumamwa.
Madokotala nthawi zambiri amalangiza kuti, "Chotsani ludzu ndi madzi." Chotsani ludzu, chotsani, chotsaniSambani, sambani Chotsani, chotsani Chotsani, chotsaniChepetsani, tengani Chotsani, tengani Chotsani, tengani Chotsani, chotsa Chotsani, chotsaPumulani, pumulani Chotsani, chotsani Chotsani, chotsaniChotsani, chotsani, chotsani, chotsaniChotsani, "Khalani chete, tsekaniKumwa madzi ambiri kapena ochepa kwambiri kungakhale koopsa. Chifukwa chakuti mankhwalawa amachititsa kuti thupi lanu lisunge madzi, ngati mumwa madzi ambiri, kuchuluka kwa sodium m'magazi anu kumatha kuchepa kwambiri.
Matenda
Ngati mukumva kupweteka m'mimba, kusanza, kapena kutsegula m'mimba, kapena ngati mukudwala malungo ndi matenda, siyani kumwa mankhwalawa nthawi yomweyo ndipo funsani dokotala wanu. Izi zili choncho chifukwa madzi ambiri amatha kutuluka m'thupi panthawiyi, ndipo kupitiriza kugwiritsa ntchito mankhwalawa kungayambitse kusintha kwakukulu kwa sodium m'thupi.
Zotsatirapo zomwe zingachitike chifukwa cha mankhwalawa
Monga mankhwala ena aliwonse, Desmopressin ikhoza kukhala ndi zotsatirapo zake. Zina zimakhala zazing'ono, koma zina zimafuna chisamaliro chapadera.
| Zotsatira Zam'mbali | Kufotokozera ndi choti muchite |
|---|---|
| Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala wanu nthawi yomweyo | |
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa nkhope, milomo kapena lilime. Funsani dokotala nthawi yomweyo. |
| Zizindikiro za sodium yochepa m'thupi | Mutu waukulu, kugona, chizungulire, kusokonezeka, nseru, kusanza, kugwedezeka kwa minofu, kusakhazikika, kapena kugwidwa ndi khunyu. Izi ndi zadzidzidzi. Pitani ku ETU nthawi yomweyo. |
| Kulemera mwadzidzidzi kapena kutupa | Kutupa m'miyendo kapena m'mapazi, kuwonjezeka kwa thupi mwadzidzidzi. Ichi ndi chizindikiro cha kusunga madzi m'thupi. |
| Kuvuta kupuma | Kuvuta kupuma, kupweteka pachifuwa kapena kulimba. |
| Kusintha kwa kugunda kwa mtima | Kugunda kwa mtima mofulumira kapena kosasinthasintha. |
| Zomwe muyenera kuuza dokotala wanu ngati zikupitirira kapena zikukuvutitsani | |
| Mutu | Mutu pang'ono ungachitike. |
| Pakamwa pouma | Kumva pakamwa pouma. |
| Kusanza pang'ono | Kusamva bwino m'mimba kapena nseru. |
Kodi mumasunga bwanji mankhwala kukhala otetezeka?
- Onetsetsani kuti mwasunga pamalo omwe ana sangafikire .
- Sungani kutentha kwa chipinda (pakati pa madigiri 20-25 Celsius). Tetezani ku kutentha kwambiri ndi dzuwa lachindunji.
- Tayani mankhwala omwe atha ntchito popanda kuwagwiritsa ntchito.
Uthenga Wopita Nawo Kunyumba
- Desmopressin ndi mankhwala omwe amawongolera kuchuluka kwa mkodzo wopangidwa ndi impso ndipo ayenera kugwiritsidwa ntchito pokhapokha ngati dokotala walangiza.
- Samalani kwambiri ndi kuchuluka kwa madzi omwe mumamwa mukamamwa mankhwalawa. Musamwe madzi ochulukirapo kapena ochepa kuposa momwe dokotala wanu wanenera.
- Ngati mukumva zizindikiro monga mutu waukulu, chizungulire, chisokonezo, kapena kusanza, ichi chingakhale chizindikiro choopsa cha kuchuluka kwa sodium m'magazi. Pitani kwa dokotala nthawi yomweyo.
- Siyani kumwa mankhwalawo ndipo funsani dokotala ngati mukumva kusanza, kuvutika m'mimba, kapena kutentha thupi.
- Mankhwalawa ndi a inu nokha. Musagawane ndi wina aliyense pazifukwa zilizonse.
👩🏽⚕️ Mafunso ena (Mafunso Ofunsidwa Kawirikawiri)
💬 Kodi mapiritsi a Desmopressin / DDAVP amagwiritsidwa ntchito pa chiyani?
Uwu ndi mankhwala othandiza kwambiri poletsa 'diabetes insipidus' yochuluka komanso 'kunyowa pabedi' mwa ana! Umalowetsa mahomoni achilengedwe (ADH) opangidwa ndi ubongo wathu m'thupi, ndikuyamwanso madzi omwe amatuluka ngati mkodzo.
💬 Kodi mungatani kuti muchepetse vuto la kusadziletsa/kunyowa pabedi pogwiritsa ntchito mankhwala opangidwa awa (Desmopressin)?
Kawirikawiri, ubongo umatumiza malangizo ku impso zathu kuti 'zisunge madzi m'thupi' kudzera mu hormone ya 'ADH'! Ubongo wa anthu ena supanga izi. Mankhwalawa (piritsi/spray) akalowa m'thupi, amapita mwachindunji ku impso (ma V2 receptors mu impso) ndikutseka zipata zonse zomwe zimalowetsa madzi, monga kutseka pompo, ndikuletsa kupanga mkodzo 100%.
💬 Kodi ndi ngozi yotani (Chenjezo la Black Box) yomwe ingachitike mukamwa mapiritsi (Desmopressin) omwe amaletsa kupanga mkodzo?
Choopsa chachikulu cha izi ndi 'Hyponatremia / Water Intoxication'! Popeza simukukodza, ngati mumwa madzi/madzi ambiri mutamwa piritsi ili, madzi onsewo adzadzaza thupi lanu ndipo 100% ya mchere womwe uli m'magazi anu udzasungunuka. Ngati mcherewo utsika, wodwalayo akhoza kugwidwa ndi khunyu mwadzidzidzi ndipo amakhala ndi chikomokere ndikufa! (Chifukwa chake, musamwe izi ngati muli ndi ludzu lalikulu la madzi).
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