Kodi pituitary gland yanu imagwira ntchito mopitirira muyeso? (Hyperpituitarism) Tiyeni tikambirane izi mwachidule!

Kodi mwadzidzidzi mwaona kusintha kwakukulu m'thupi lanu? Mwina mwawonjezeka thupi mwadzidzidzi, nkhope yanu yasintha, kapena mukumva kutopa tsiku lonse mosasamala kanthu kuti mumagona tulo totani? Nthawi zambiri timaiwala zinthu izi, poganiza kuti ndi zachilendo. Koma kodi mukudziwa kuti kumbuyo kwa zina mwa zinthuzi, pakhoza kukhala kusintha kwa kagwiridwe ka ntchito ka gland kakang'ono, koma kofunikira kwambiri muubongo wathu. Ndicho chimene tikukamba lero.

Kodi pituitary gland iyi imatchedwa chiyani? N’chifukwa chiyani ndi yofunika kwambiri?

Taganizirani thupi lanu ngati kampani yayikulu. Mkulu wa kampani imeneyo, bwana amene amalamulira chilichonse, ndi pituitary gland . Ichi ndi gland kakang'ono, kakang'ono ngati nandolo, komwe kali pansi pa ubongo wathu, kakang'ono ngati chitumbuwa. Ngakhale kuti ndi kakang'ono, kamagwira ntchito zambiri. Ndicho chifukwa chake nthawi zina kamatchedwa "master gland."

Mwachidule, imalamulira ntchito ya tiziwalo tina ta endocrine m'thupi lathu. Mwachitsanzo, chithokomiro, tiziwalo ta adrenal, ndi njira yathu yoberekera, monga mazira kapena ma testes, zimayendetsedwa ndi mahomoni omwe amatulutsidwa ndi chithokomiro cha pituitary.

Monga momwe zimakhalira ndi thermostat m'nyumba mwathu. Imayang'anira kutentha kwa m'nyumba nthawi zonse ndipo imasunga kutentha komweko poyatsa/kuzima AC kapena chotenthetsera, sichoncho? Mofananamo, pituitary gland nthawi zonse imayang'anira kuchuluka kwa mahomoni m'thupi lathu ndikutumiza zizindikiro ku ma gland ena kuti atulutse mahomoni ofunikira panthawi yoyenera.

Kodi hyperpituitarism iyi ndi chiyani?

Mwachidule, Hyperpituitarism ndi pamene pituitary gland yomwe yatchulidwayi imagwira ntchito mopitirira muyeso, ndikutulutsa mahomoni ambiri m'magazi mwathu kuposa momwe kungafunikire. Zili ngati bwana wa kampani akugwira ntchito mopitirira muyeso ndikusokoneza chilichonse.

Nthawi zambiri, kutanthauza kuti, pafupifupi 99% ya nthawi, chomwe chimayambitsa ndi chotupa chaching'ono, chosakhala khansa (chosaopsa). M'mawu azachipatala, timatcha ichi kuti pituitary adenoma . Chotupachi chimalimbikitsa gland ndipo chimapangitsa kuti ipange mahomoni ambiri kuposa momwe iyenera kukhalira.

Mahomoni opangidwa ndi pituitary gland ndi ntchito zawo

Pali magawo atatu akuluakulu a pituitary gland. Gawo lililonse limatulutsa mahomoni osiyanasiyana. Tiyeni tiwone zomwe zili ndi zomwe zimawachitikira.

Matenda omwe angachitike chifukwa cha kugwira ntchito mopitirira muyeso kwa pituitary gland

Matenda omwe amabwera amasiyana malinga ndi mahomoni omwe amapangidwa mopitirira muyeso ndi pituitary gland. Tiyeni tiwone matenda akuluakulu omwe amawonekera.

• Matenda a Cushing: Ngati mahomoni a ACTH apangidwa mopitirira muyeso, kuchuluka kwa cortisol m'thupi lathu kumawonjezeka kwambiri. Izi zimatchedwa Matenda a Cushing.
• Acromegaly: Matendawa amapezeka pamene mahomoni okula (GH) amapangidwa mopitirira muyeso akakula. Izi zimapangitsa kuti mafupa a manja, mapazi, ndi nkhope akule kwambiri. Ngati izi zimachitika ali mwana, zimatchedwa gigantism .
• Hyperthyroidism: Ngati TSH yochuluka ipangidwa (izi sizichitika kawirikawiri), chithokomiro chimayamba kugwira ntchito mopitirira muyeso ndipo kagayidwe ka thupi m'thupi kamafulumira.
• Prolactinoma: Chotupa (adenoma) m'maselo omwe amapanga mahomoni otchedwa prolactin chimayambitsa kupanga mahomoni ambiri. Izi zitha kukhudza kwambiri thanzi la kubereka.

Kodi zizindikiro za matenda amenewa ndi ziti?

Zizindikiro zomwe zimabwera ndi vuto lililonse mwa izi ndi zosiyana. Ngati muli ndi zizindikiro izi, ndikofunikira kwambiri kukaonana ndi dokotala.

Kodi vutoli limakhudza bwanji ana?

Matenda a hyperpituitarism ndi osowa kwambiri mwa ana. Ngati achitika, nthawi zambiri amayamba chifukwa cha adenoma yaying'ono ya pituitary. Mtundu wofala kwambiri wa chotupa mwa ana ndi chotupa chomwe chimapanga prolactin (Prolactinomas).

• Kwa atsikana: Kuchedwa kutha msinkhu, kutha kwa msambo (amenorrhea), komanso kusagwira bwino ntchito kwa mazira kungachitike.
• Anyamata: Zotupa zazikulu (macroprolactinomas) zimakhala ndi mwayi waukulu woti ziyambe kukula. Chifukwa chakuti zotupazi ndi zazikulu, zimatha kukakamiza mitsempha muubongo, zomwe zimayambitsa mutu ndi mavuto a masomphenya. Zingayambitsenso kuchedwa kwa msinkhu komanso mavuto a kukula.

Kodi dokotala amazindikira bwanji matendawa?

Mukatiuza za zizindikiro zanu, dokotala adzayamba kaye wakuyang'anani mosamala. Kenako, angachite mayeso angapo kuti atsimikizire kuti mwapezeka ndi matendawa.

1. Kuyezetsa magazi ndi mkodzo: Izi zidzayesa kuchuluka kwa mahomoni m'magazi mwanu komanso mwina mkodzo. Mwachitsanzo, zidzayesa kuchuluka kwa prolactin, cortisol, ndi hormone yokulira m'thupi mwanu.

2. Zojambulajambula:Ngati pali vuto la mahomoni, scan imachitidwa kuti ione ngati pali chotupa cha pituitary. Scan yodziwika kwambiri yomwe imagwiritsidwa ntchito pa izi ndi MRI (Magnetic Resonance Imaging) . Kwa munthu amene sangathe kuchitidwa MRI (monga munthu amene ali ndi pacemaker), scan ya CT (Computed Tomography) ingathenso kuchitidwa.

3. Mayeso apadera: Nthawi zina, kuti adziwe matenda monga Cushing's syndrome molondola, mayeso apadera, monga kuyeza kuchuluka kwa cortisol m'malovu, angafunike.

Kodi mankhwala ake ndi otani?

Chithandizo cha vutoli chimadalira zinthu monga mtundu wa vuto lomwe muli nalo, kukula kwa chotupacho, ndi thanzi lanu lonse. Pali njira zitatu zazikulu zochiritsira.

1. Mankhwala

Kawirikawiri, chithandizo choyamba ndi mankhwala. Mankhwalawa amagwiritsidwa ntchito:

• Kulamulira kuchuluka kwa mahomoni.
• Nthawi zina kuchepetsa kukula kwa chotupacho.
• Mankhwala ndi othandiza kwambiri, makamaka pa prolactinoma. Anthu opitilira 80% amabwerera ku milingo yabwinobwino ya mahomoni.

2. Opaleshoni

Ngati mankhwala sangathe kulamulira chotupacho, kapena ngati chotupacho chakula mokwanira kuti chikhudze masomphenya, gawo lotsatira ndikuchotsa chotupacho mwa opaleshoni.

• Opaleshoni yofala kwambiri imatchedwa transsphenoidal adenomectomy . Izi zimaphatikizapo kudula pang'ono kudzera m'mphuno kapena mkati mwa mlomo wapamwamba kuti ufike ku pituitary gland ndikuchotsa chotupa popanda kuwononga ubongo.
• Ngati opaleshoniyi ichitidwa ndi dokotala wodziwa bwino ntchito yake, chiwopsezo cha kupambana chimakhala choposa 80%.

3. Chithandizo cha Radiation

Chithandizo cha radiation chimagwiritsidwa ntchito ngati gawo la chotupacho latsala pambuyo pa opaleshoni, kapena ngati opaleshoniyo singatheke.

• Izi zikuphatikizapo kuyang'ana kuwala kwamphamvu kwambiri ku chotupacho ndikuwononga maselo amenewo.
• Njira zamakono monga stereotactic therapy zitha kuchepetsa kwambiri kuwonongeka kwa minofu yathanzi yozungulira.

Kodi n'zotheka kukhala ndi thanzi labwino ndi vutoli?

Inde, ndithudi. Matenda ambiri omwe amayamba chifukwa cha hyperpituitarism amatha kuthandizidwa bwino ndi mankhwala ndi mankhwala ena. Chofunika kwambiri ndikufunsa upangiri wa dokotala zizindikiro zikangoyamba kuwonekera ndikutsatira bwino mankhwala omwe aperekedwa. Matenda ena angafunike mankhwala a nthawi yayitali kapena kuyang'aniridwa ndi dokotala. Komabe, ndi chithandizo choyenera, anthu ambiri amatha kukhala ndi moyo wathanzi, wachimwemwe, komanso wabwinobwino.