Tiyeni tiphunzire zambiri za Leptin, yomwe imakuthandizani kulamulira kulemera kwanu mwachinsinsi.

Tonsefe nthawi zina timada nkhawa ndi kulemera kwathu, sichoncho? Anthu ena amafuna kuchepetsa thupi, pomwe ena amafuna kukhala ndi kulemera kwabwino. Kodi munayamba mwaganizapo kuti pali njira ina mkati mwa matupi athu yomwe imatithandiza kulamulira kulemera kwathu? Leptin ndi imodzi mwa njira zodzitetezera mwachinsinsi. Lero, tiyeni tikambirane za leptin iyi m'njira yosavuta yomwe mungamvetse.

Kodi Leptin ndi chiyani?

Mwachidule, leptin ndi mahomoni opangidwa ndi maselo amafuta a thupi lanu, kapena minofu yamafuta . Ili ngati njira yaying'ono yolumikizirana yomwe imakuthandizani kuwongolera kulemera kwanu kwa nthawi yayitali. Kodi imachita bwanji izi? Leptin imawongolera njala yanu komanso imakuthandizani kumva kukhuta, kapena kukhuta .

Taganizirani izi motere: leptin ili ngati mthenga amene amauza ubongo wanu kuchuluka kwa mafuta omwe muli nawo m'thupi lanu. Asayansi adapeza leptin posachedwapa mu 1994. Chifukwa chake pali kafukufuku wambiri womwe ukuchitika, kuti amvetsetse momwe imagwirira ntchito. Leptin ikufufuzidwa kale chifukwa cha ntchito yake yochepetsa kunenepa, matenda a Alzheimer's , thanzi lobereka, komanso kusabereka .

Mukamva kuti leptin imalamulira kulemera, mungaganize kuti, "O... choncho ndikuganiza kuti ndiyenera kupeza njira yowongolera leptin." Koma, kunena zoona, kugwiritsa ntchito mahomoni amenewa sikophweka monga momwe mukuganizira.

Kodi kwenikweni chimachitika ndi chiyani ndi leptin?

Ntchito yaikulu ya Leptin ndikukuthandizani kuti thupi lanu likhale lolimba. Izi zikutanthauza kuti, zimathandiza kupanga mgwirizano wa nthawi yayitali pakati pa kuchuluka kwa chakudya chomwe mumadya ndi kuchuluka kwa mphamvu zomwe thupi lanu limagwiritsa ntchito. Leptin imakulepheretsani kumva njala nthawi zonse. Imawongoleranso zizindikiro za njala zomwe zimabwera pamene thupi silikufuna mphamvu, kapena ma calories .

Leptin imagwira ntchito makamaka pokhudza gawo la ubongo wanu lotchedwa hypothalamus . Hypothalamus ndi malo ofunikira kwambiri olamulira njala ndi kugwiritsa ntchito mphamvu. Komabe, palinso ma receptors a leptin m'zigawo zina za thupi.

Chofunika kwambiri n’chakuti leptin sikuti imangolamulira njala yanu kuyambira pa chakudya chimodzi kupita ku china, koma m’malo mwake, imathandiza kusintha kadyedwe kanu pakapita nthawi, kuwongolera mphamvu zomwe mumagwiritsa ntchito, komanso kukuthandizani kukhala ndi kulemera kokhazikika.

Mukayesa kuchepetsa thupi, kuchuluka kwa leptin kumawonjezeka. Kodi zimenezo zimagwira ntchito bwanji? Pamene thupi lanu likutaya mafuta, kuchuluka kwa leptin kumachepa. Izi zimatumiza chizindikiro ku thupi lanu, kuti, "O, sindikudya mokwanira, ndili ndi njala." Izi zimakupangitsani kumva njala kwambiri komanso kukhala ndi chilakolako. Izi zingapangitse kuti mudye mopitirira muyeso. Ndicho chifukwa chake nthawi zina zimakhala zovuta kuti muchepetse thupi.

Asayansi akuphunzirabe za leptin. Akukhulupirira kuti imakhudzanso:

• Kagayidwe ka thupi kanu
• Dongosolo la endocrine, ndiko kuti, dongosolo la mahomoni
• Chitetezo chamthupi

Kodi kuchuluka kwa leptin kumayendetsedwa bwanji?

Leptin imapangidwa ndi kutulutsidwa ndi minofu yoyera ya mafuta m'thupi lanu, kapena maselo oyera amafuta. Maselo oyera amafuta awa ndi mtundu waukulu wa mafuta m'thupi lathu.

Popeza leptin imachokera ku maselo amafuta, kuchuluka kwa leptin m'magazi anu kumagwirizana mwachindunji ndi kuchuluka kwa mafuta m'thupi lanu. Mwachidule, ngati muli ndi mafuta ochepa m'thupi, muli ndi leptin yochepa. Ngati muli ndi mafuta ambiri m'thupi, muli ndi leptin yambiri.

Ngati mafuta m'thupi lanu akuwonjezeka pakapita nthawi, kuchuluka kwa leptin kumawonjezeka. Mosiyana ndi zimenezi, ngati mafuta m'thupi lanu akuchepa, kuchuluka kwa leptin kumachepa.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa leptin kukwera?

Munthu wonenepa kwambiri akhoza kukhala ndi leptin yambiri m'thupi mwake. Izi zimatchedwa hyperleptinemia . Leptin ikawonjezeka motere, vuto lingachitike lomwe thupi siliyankha leptin. Izi zimatchedwa kukana leptin .

Matenda ena omwe angagwirizane ndi hyperleptinemia ndi awa:

• Kuvutika maganizo
• Kukonda kudya
• Matenda a neurodegenerative
• Matenda a chiwindi amafuta osamwa mowa ( NAFLD )
• Matenda a Rabson-Mendenhall

Kodi Kukana kwa Leptin ndi Chiyani?

Ngati muli ndi vuto la leptin, ubongo wanu suyankha leptin mwachibadwa. Ngakhale kuti leptin ikupitiriza kutumiza zizindikiro ku ubongo wanu, simukumva "kukhuta". Zotsatira zake, mukupitiriza kudya, ngakhale kuti muli ndi mafuta ambiri m'thupi lanu.

Chifukwa cha kusowa kwa leptin kumeneku, thupi lanu limaganiza kuti "mukuvutika ndi njala." Kuti musunge mphamvu, ubongo wanu umachepetsa mphamvu zanu ndikuchepetsa kuchuluka kwa ma calories omwe mumawotcha mukapuma. Izi zikutanthauza kuti Basal Metabolic Rate (BMR) yanu imachepa.

Choncho, kukana kwa leptin kumakupangitsani kumva njala nthawi zonse, ndipo BMR yanu imachepanso. Izi zimapangitsa kuti kunenepa kukhale koipa.

Asayansi akuyesera kupanga mankhwala omwe angathandize kuchiza kukana kwa leptin.

Zizindikiro za kukana leptin

Zizindikiro zazikulu za kukana leptin ndi njala yosalekeza, kapena hyperphagia , komanso kudya kwambiri. Zizindikirozi zimachitika mukakhala ndi mafuta ambiri m'thupi, mwina mafuta ambiri.

Komabe, zizindikirozi zitha kuchitika chifukwa cha zinthu zina zambiri, osati kukana leptin kokha. Popeza asayansi akuphunzirabe za leptin, ndizotheka kuti zizindikiro zina za kukana leptin zidzapezeka mtsogolo.

Kodi chimachitika ndi chiyani ngati muli ndi vuto la kuchepa kwa leptin?

Kusowa kwa Leptin, komwe kumadziwikanso kuti hypoleptinemia, ndi vuto losowa kwambiri. Vuto lalikulu lomwe limagwirizanitsidwa ndi izi ndi kusowa kwa leptin kobadwa nako . Ili ndi vuto la majini lomwe mumabadwa nalo. Izi zikutanthauza kuti minofu yanu yamafuta singathe kupanga leptin.

Leptin ikatayika, thupi lanu limaganiza kuti palibe mafuta m'thupi. Izi zimapangitsa kuti mukhale ndi njala komanso chilakolako chosalamulirika. Pachifukwa ichi, ana aang'ono omwe ali ndi vuto la leptin lobadwa nalo amakhala ndi kunenepa kwambiri kwa kalasi yachitatu komanso kuchedwa kutha msinkhu.

Vutoli limagwirizananso ndi matenda ena angapo:

• Dyslipidemia (kusalinganika kwa mafuta, monga cholesterol ndi triglycerides)
• Matenda a chiwindi chamafuta
• Matenda opatsirana pafupipafupi a bakiteriya
• Hyperinsulinemia (kupanga insulini yambiri)
• Hypogonadotropic hypogonadism (kuchepa kwa mahomoni ogonana)

Kodi mungayang'ane bwanji kuchuluka kwa leptin m'magazi?

Kuyezetsa magazi kungathandize kudziwa kuchuluka kwa leptin m'magazi mwanu. Komabe, madokotala nthawi zambiri samayang'ana kuchuluka kwa leptin m'thupi la munthu aliyense. Amangoganizira zoyesa leptin m'mikhalidwe iyi:

• Ngati mwana wanu ali ndi kunenepa kwambiri kwa giredi 3
• Ngati muli ndi kunenepa kwambiri ndipo nthawi zonse mumakhala ndi njala

Kodi kuchuluka kwa leptin m'magazi ndi kotani?

Kawirikawiri, kuchuluka kwa leptin m'magazi kungakhale motere:

• Kwa akazi: 0.5 mpaka 15.2 nanograms pa milliliter ( 0.5 mpaka 15.2 ng/mL )
• Kwa amuna: 0.5 mpaka 12.5 nanograms pa milliliter ( 0.5 mpaka 12.5 ng/mL )

Komabe, miyezo yabwinobwino iyi imatha kusiyana pang'ono kuchokera ku labu kupita ku labu. Chifukwa chake, onetsetsani kuti mwayang'ana mulingo woyenera pa lipoti lanu la mayeso, kapena funsani dokotala wanu ngati muli ndi mafunso okhudza zotsatira zanu.

Kodi ndingawonjezere bwanji kuchuluka kwa leptin m'magazi anga?

Ndipotu, palibe zambiri zomwe mungachite kuti muwonjezere kuchuluka kwa leptin yanu kuti muchepetse njala kapena chilakolako. Izi zili choncho chifukwa kuchuluka kwa leptin yanu kumagwirizana mwachindunji ndi kuchuluka kwa minofu yamafuta yomwe muli nayo m'thupi lanu.

Kafukufuku wina adapeza kuti anthu omwe sagona mokwanira amakhala ndi ghrelin (hormone ya njala) yambiri komanso leptin yochepa. Chifukwa chake, kugona mokwanira kungathandize kuti mahomoni anu azikhala bwino.

Asayansi agwirizanitsa leptin ndi triglycerides(Iyi ndi mtundu wa mafuta otchedwa lipids). Kafukufuku wina wasonyeza kuti pamene kuchuluka kwa triglyceride kuli kokwera, kumakhudza momwe leptin imagwirira ntchito. Koma pali malingaliro osiyanasiyana pa kafukufukuyu. Asayansi ena amaganiza kuti zakudya zomwe zimapangidwira kuchepetsa triglycerides zingathandize kukweza kuchuluka kwa leptin, koma ena sagwirizana nazo.

Ndi zakudya ziti zomwe zili ndi leptin yambiri?

Leptin ndi mahomoni omwe thupi lanu limapanga, osati michere monga vitamini C kapena mapuloteni. Chifukwa chake, palibe chakudya chomwe chili ndi leptin.

Popeza leptin ndi chinthu chatsopano chomwe chapezeka, asayansi akuphunzirabe zambiri za leptin, makamaka momwe imakhudzira kunenepa kwambiri komanso kuchepa thupi. Pamene mafuta m'thupi lanu ali ochepa, zimakhala zovuta kuchepetsa thupi chifukwa ntchito ya leptin poyambitsa chizindikiro cha "njala" m'thupi.

Uthenga Wopita Nawo Kunyumba

Chabwino, kuchokera pa zomwe takambirana za leptin, mutha kukumbukira izi:

• Leptin ndi hormone yopangidwa ndi maselo anu amafuta .
• Chofunika kwambiri pa izi ndichakuti zimakuthandizani kulamulira kulemera kwanu pakapita nthawi ndipo zimakupatsani kumva "kukhuta" .
• Mafuta m'thupi lanu akamawonjezeka, kuchuluka kwa leptin kumawonjezeka , ndipo mafuta m'thupi lanu akamachepa, kuchuluka kwa leptin kumachepa.
• Kukana kwa leptin kumachitika pamene thupi lili ndi leptin koma ubongo suyankha bwino. Izi zingayambitse kunenepa.
• Kusowa kwa Leptin m'thupi n'kosowa kwambiri .
• Chakudya chilibe leptin, chifukwa imapangidwa m'thupi.
• Moyo wathanzi, makamaka kugona tulo tokwanira , ungathandize kuti mahomoni azikhala bwino.

Ngati mukuda nkhawa ndi kulemera kwanu kapena mukufuna upangiri wa momwe mungachepetsere thupi lanu bwino, lankhulani ndi dokotala wanu. Muthanso kuonana ndi dokotala yemwe ndi katswiri wa mahomoni, katswiri wa matenda a endocrinologist, kuti mukambirane za mapulogalamu ochepetsa thupi. Chofunika kwambiri ndikusamalira thanzi lanu kaye.

Leptin , kuchepetsa kulemera, mahomoni, kunenepa kwambiri, kukana leptin, njala, kukhuta