Kodi mwana wanu nthawi zambiri amakhala ndi malungo osadziwikiratu? Izi zitha kukhala chifukwa cha matenda a SAID (Systemic Autoinflammatory Diseases)!

Kodi mwana wanu amadwala malungo nthawi zonse? Nthawi zina amadwala malungo kamodzi kapena kawiri pamwezi, koma madokotala amati palibe matenda, kutanthauza kuti palibe kachilombo kapena mabakiteriya m'thupi. Nthawi ngati mayi kapena bambo, mumakhala ndi nzeru kwambiri kumva mantha ndi nkhawa zambiri. "N'chifukwa chiyani izi zikuchitika kwa mwana wanga?" Mwina mwaganizapo kambirimbiri. Mwina chifukwa cha izi ndi chinthu chomwe simunamvepo kale. Lero, tikambirana za SAIDs (Systemic Autoinflammatory Diseases), zomwe zimakhala zovuta kuzimvetsa ndipo zingayambitse malungo pafupipafupi. Kale, izi zimatchedwa `(Periodic Fever Syndromes)` kapena `(Recurrent Fever Syndromes)`.

Kodi matenda a SAID (Systemic Autoinflammatory Diseases) ndi ati?

Mwachidule, ma SAID ndi gulu la matenda omwe amabwera chifukwa cha vuto losagwira ntchito bwino kapena vuto lolamulira chitetezo chamthupi lathu. Chomwe chimachitika ndichakuti, popanda chifukwa china chilichonse chakunja, ndiko kuti, kachilombo kapena mabakiteriya, thupi limangopanga kutupa. Ichi ndichifukwa chake malungo obwerezabwereza amabwera.

Tsopano mwina mukuganiza kuti, "O, kodi iyi ndi imodzi mwa Matenda a Autoimmune?" Ayi, awiriwa ndi osiyana pang'ono. Mwachitsanzo, mu Matenda a Autoimmune, mu matenda monga Rheumatoid Arthritis kapena Lupus, chitetezo chamthupi chathu chosinthika chimaukira maselo ake athanzi molakwika. Koma mu SAIDs, vuto lili ndi chitetezo chamthupi chobadwa nacho.

Matenda a SAID ndi osowa kwambiri kuposa matenda a Autoimmune. Nthawi zambiri, matendawa ndi obadwa nawo , zomwe zikutanthauza kuti amayamba chifukwa cha kusintha kwa majini kapena mtundu wina wa matenda.

Matenda a SAID nthawi zambiri (koma osati nthawi zonse) amayamba mwana wanu ali khanda kapena mwana wakhanda . Mwanayo amakhala ndi nthawi zina kapena kuukira matendawa nthawi zina. Pa nthawi imeneyi, malungo ndi zizindikiro zina zimatha kuwonekera. Komabe, pakati pa "kuukira" kumeneku, mwanayo sangakhale ndi zizindikiro. Palibe mankhwala a SAID, koma nthawi zambiri pamakhala mankhwala othandiza oletsa zizindikirozo.

Kodi mitundu ikuluikulu ya SAIDs ndi iti?

Ofufuza apeza mitundu pafupifupi 60 ya ma SAID, ndipo ena akupezeka. Nazi zina mwa mitundu yodziwika bwino:

• Matenda a Mediterranean omwe amayambitsidwa ndi majini (FMF): Uwu ndi matenda ofala kwambiri omwe amabadwa nawo nthawi zambiri. Angayambitse kutupa kowawa m'mimba, pachifuwa, ndi m'malo olumikizirana mafupa a mwana.
• Malungo a nthawi ndi nthawi, aphthous-stomatitis, pharyngitis, adenitis (PFAPA): Izi nthawi zambiri zimayamba mwa ana aang'ono, nthawi zambiri asanakwanitse zaka 4. Komabe, mwa ana ena, vutoli limatha kutha akakwanitsa zaka 10.
• Matenda a malungo obwera chifukwa cha tumor necrosis factor receptor-associated periodic fever (TRAPS): Izi zingachitike kuyambira ali mwana mpaka ali wachinyamata, ndipo nthawi zina mpaka atakula.
• Kusowa kwa Mevalonate kinase (MKD): Poyamba kumadziwika kuti Hyper-IgD syndrome, nthawi zambiri kumayamba mwana asanakwanitse chaka chimodzi.
• Matenda otupa omwe amabwera chifukwa cha NLRP3: Izi kale zinkatchedwa Cryopyrin-associated periodic syndromes (CAPS). Pali mitundu ina itatu mkati mwa izi.
• Matenda a Adult-onset Still's (AOSD): Monga momwe dzinalo likusonyezera, matendawa amayamba munthu akakula. Ndi mtundu wa matenda achikulire otchedwa systemic juvenile idiopathic arthritis (JIA).
• Matenda a granulomatous omwe amagwirizana ndi NOD-2 (Blau syndrome): Izi nthawi zambiri zimayamba asanakwanitse zaka 4. Zimakhudza kwambiri khungu, maso, ndi mafupa a mwana.

Kodi zizindikiro za SAIDs ndi ziti?

Zizindikiro za SAID nthawi zambiri zimayamba ali mwana. Chizindikiro chachikulu komanso chofala kwambiri ndi kutentha thupi nthawi ndi nthawi . Monga tanenera kale, mwana akhoza kukhala bwino nthawi yomwe palibe kutentha thupi. Komabe, pali zizindikiro zina zomwe zimakhala zapadera pa mtundu uliwonse wa SAID:

• Mu matenda a FMF: Mimba ya mwana, chifuwa chake, ndi malo olumikizirana mafupa zimatha kupweteka kwambiri komanso kutupa. Nthawi zina, pakhoza kukhala ziphuphu pakhungu pa miyendo ya m'munsi kapena akakolo ake.
• Mu PFAPA: Kupweteka pakhosi, zilonda pakamwa, kutupa kwa ma lymph nodes m'khosi. Izi ndi zizindikiro zazikulu.
• Mu TRAPS: Thupi likhoza kuzizira komanso kutentha thupi. Mwanayo akhoza kukhala ndi ululu wa minofu m'thupi ndi m'manja. Ziphuphu zofiira zopweteka zingawonekere, zomwe zingafalikire kuchokera m'manja kupita kumapazi kenako ku thupi.
• Mu MKD: Mutha kukhala ndi zizindikiro zofanana ndi chimfine monga kuzizira, mutu, kupweteka m'mimba, kusowa chilakolako cha chakudya, ndi zizindikiro zina.
• Mu matenda a NLRP3: ziphuphu pakhungu, mutu, kufooka, kupweteka kwa mafupa, ndi kutupa kwa maso (conjunctivitis) kungachitike.
• Mu AOSD: ziphuphu pakhungu, kupweteka kwa mafupa, kupweteka kwa minofu. Anthu ena amathanso kumva kupweteka pakhosi, kupweteka m'mimba, kutopa, komanso kumva kufooka.
• Mu matenda a Blau: Mwana akhoza kukhala ndi zilonda pakhungu m'manja, miyendo, kapena pakati pa msambo. Akhozanso kumva kupweteka kwa mafupa ndi kupweteka kwa maso.

Tangoganizirani, mwana wamkazi wa Nalini wakhala akudwala malungo aakulu kwa masiku atatu kapena anayi mwezi uliwonse kwa miyezi ingapo yapitayi. Kuphatikiza apo, akuyambanso kukhala ndi zilonda zazing'ono mkamwa mwake ndi zotupa pakhosi pake. Atawonetsa dokotala, anati mwina ndi PFAPA.

Kodi zifukwa za SAIDs ndi ziti?

Matenda ambiri a SAID ndi matenda a majini . Izi zikutanthauza kuti matenda aliwonsewa amayamba chifukwa cha kusiyana kwa majini athu. Nazi mitundu yodziwika bwino ya SAIDs ndi majini omwe amawakhudza:

• FMF: Jini yotchedwa `(MEFV)`. Jini iyi imaphunzitsa kupanga puloteni `(pyrin)`.
• PFAPA: Jini yeniyeni yomwe imakhudza izi sinadziwikebe.
• MISAMBO: Jini yotchedwa `(TNFRSF1A)`. Apa ndi pomwe malangizo opangira puloteni `(cholandirira chotupa cha necrosis - TNFR)` amachokera.
• MKD: Jini `(MVK)`. Izi zimalangiza kupanga puloteni yotchedwa `(mevalonic kinase)`.
• Matenda a NLRP3: Jini yotchedwa `(NLRP3)`. Izi zimapereka malangizo opangira puloteni yotchedwa `(cryopyrin)`.
• AOSD: Chifukwa chenicheni cha izi sichikudziwikabe.
• Matenda a Blau: Jini `(NOD2)`. Izi zimalangiza kupanga mapuloteni `(NOD2)`.

Tsatanetsatane wa majini awa ungawoneke wovuta pang'ono kwa inu. Mwachidule, majini awa amakhudza kupanga mapuloteni ena omwe amalamulira kutupa m'matupi athu. Ndicho chifukwa chake thupi limapanga matenda otupa popanda chifukwa.

Kodi chingachitike n’chiyani ngati matenda a SAID sakuchiritsidwa bwino?

Ndikofunikira kwambiri kupeza chithandizo choyenera cha SAIDs izi. Chifukwa ngati kutupa m'thupi kukupitirira, vuto lotchedwa `(amyloidosis)` lingachitike. Izi zikutanthauza kuti mtundu wina wa mapuloteni umayikidwa mu impso zathu, zomwe zingayambitse kuwonongeka kosatha kwa impso . Chifukwa chake, ngati pali zizindikiro, ndikofunikira kwambiri kufunafuna upangiri wa dokotala popanda kuzinyalanyaza.

Kodi madokotala amazindikira bwanji matenda a SAID?

Kuzindikira matenda a SAID kungakhale kovuta chifukwa zizindikiro zake zimatha kufanana ndi za matenda ena akuluakulu, monga lupus kapena lymphoma. Chifukwa chake , ndi bwino kuonana ndi dokotala wa nyamakazi, dokotala yemwe ali ndi maphunziro apadera okhudza matenda otupa , kuti adziwe bwino ndikusamalira vuto la mwana wanu.

Dokotala wa nyamakazi wa mwana wanu adzayang'ana zinthu zingapo kuti adziwe matenda a SAID. Iye adzakufunsani za zizindikiro za mwana wanu komanso ngati pali wina aliyense m'banja mwanu amene wakhala akudwala chimfine nthawi zambiri. Dokotala angaganize kuti vutoli ndi lotere ngati:

• Ngati mwana amadwala malungo pafupipafupi .
• Ngati wina m'banjamo ali ndi mbiri ya malungo pafupipafupi .
• Ngati mwanayo ndi wa fuko lina, ndiye kuti nthawi zambiri amadwala malungo ngati amenewa.

Ndi mayeso ati omwe amagwiritsidwa ntchito?

Kuti atsimikizire matendawa, dokotala wa nyamakazi wa mwana wanu angakulangizeni mayeso angapo. Ena mwa awa ndi awa:

• Mayeso a labu: Mayeso a magazi monga `(C-reactive protein - CRP)` ndi `(Complete blood count - CBC)` angayang'ane kutupa m'thupi. Mayesowa ndi `(positive)` mukakhala ndi malungo ndipo amabwerera mwakale malungo akatha.
• Kuyesa mkodzo: Mkodzo umayesedwa kuti upeze mapuloteni ambiri. Pankhani ya MKD, mkodzo umayesedwanso kuti upeze asidi wambiri wachilengedwe wotchedwa ``mevalonic acid''.
• Kuyesa majini: Kuyesa majini kungayang'ane mitundu yosiyanasiyana ya majini yomwe yatchulidwa pamwambapa. Komabe, ana ena omwe ali ndi matenda a SAID sangapeze mitundu yosiyanasiyana ya majini, kotero zotsatira za mayesowo zingakhale zoipa.

Kodi mankhwala a SAID ndi otani?

Chithandizo cha SAIDs chimadalira mtundu ndi kuopsa kwa vutoli . Palibe mankhwala a matendawa, koma mankhwala angathandize kuwongolera zizindikiro za mwana wanu . Ngati mwana wanu amakumana ndi ziwopsezo zingapo pachaka, nthawi zambiri mutha kuthana ndi zizindikirozo ndi mankhwala ochepetsa ululu ndi mankhwala oletsa kutupa (NSAIDs). Komabe, ngati vutoli ndi lalikulu kwambiri, dokotala wanu angakulangizeni njira zina zothandizira:

• FMF: Izi zitha kuchiritsidwa ndi mankhwala otchedwa `(Colchicine)` kuti achepetse kutupa. Ngati `(Colchicine)` singaperekedwe kwa mwana, mutha kuyesa mankhwala amtundu wa `(biologic)` otchedwa `(Canakinumab)`.
• PFAPA: Ma steroids monga prednisone amatha kufupikitsa nthawi ya "kuukira" kwa PFAPA. Cimetidine, mankhwala omwe amaperekedwa kwa ana ena a zilonda zam'mimba, angathandizenso kuchepetsa zizindikiro.
• MISALA: Mankhwalawa `(Canakinumab)` ndi othandiza kwambiri pa MISALA. Komanso, zizindikiro zake zitha kuthetsedwa ndi mankhwala oletsa kutupa monga `(glucocorticoids)` omwe dokotala wakupatsani.
• MKD: `(Canakinumab)` ndi mankhwala othandiza a MKD. `(NSAIDs)` kapena `(steroids)` angathandize panthawi ya "kuukira".
• Matenda a NLRP3: Mankhwala oletsa chitetezo chamthupi monga Canakinumab, Rilonacept, ndi Anakinra agwiritsidwa ntchito bwino pochiza matenda okhudzana ndi NLRP3.
• AOSD: Mankhwala osiyanasiyana oletsa kutupa monga ma steroids, mankhwala oletsa kupweteka kwa minofu ndi mafupa (DMARDs), ndi mankhwala a biologic amagwiritsidwa ntchito pochiza AOSD.
• Matenda a Blau: Kutengera ndi zizindikiro za mwana, mankhwala oletsa chitetezo chamthupi, zoletsa za tumor necrosis factor (TNF), ndi/kapena mankhwala a maso opangidwa ndi khungu angayesedwe.

Kuwerenga za mankhwala awa kungakupangitseni mantha pang'ono. Koma kumbukirani kuti, mankhwala onsewa amaperekedwa motsogozedwa ndi dokotala, m'njira yoyenera kwambiri kwa mwana. Chifukwa chake, ndikofunikira kutsatira chithandizocho monga momwe dokotala wanenera.

Kodi SAIDs status ikutha?

Matenda ena a SAID ndi matenda a moyo wonse . Ena amatha kukhalapo kwa zaka zingapo ndipo amatha akamakula . Matenda ena ndi a moyo wonse, koma pakapita nthawi, kuchuluka kwa matendawa kumatha kuchepa ndipo zizindikiro zake zimatha kuchepa. Dokotala wanu adzakufotokozerani za matenda a mwana wanu.

Kusamalira mwana yemwe ali ndi SAID kungakhale kovuta. Ngati munachitapo SAID nokha, mungagwiritse ntchito zomwe mwakumana nazo pothandiza kusamalira mwana wanu. Kumvetsetsa kwanu n'kofunika kwambiri pothandiza mwana wanu kukhala ndi vutoli moyo wake wonse.

Chofunika kwambiri ndikupempha chithandizo kuchokera kwa madokotala odziwa bwino ntchito omwe amadziwa bwino za matenda a SAID. Angathandize kuchepetsa zizindikiro za mwana wanu ndikumuthandiza kukhala ndi ubwana wabwino kwambiri.

Zinthu zofunika kwambiri kukumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, tiyeni tikambirane mfundo zazikulu zomwe muyenera kukumbukira kuchokera pa zomwe takambirana:

• Ngati mwana wanu ali ndi malungo pafupipafupi komanso osadziwikiratu , izi zitha kukhala chizindikiro cha SAID.
• Matenda a SAID samayamba chifukwa cha matenda , koma ndi vuto la chitetezo cha mthupi.
• Izi ndi matenda osowa omwe nthawi zambiri amayamba chifukwa cha majini .
• Zizindikiro zimatha kusiyana malinga ndi mtundu wa SAID, koma kutentha thupi pafupipafupi ndiye chizindikiro chachikulu .
• Ndikofunikira kuonana ndi katswiri wa matenda a rheumatism kuti mudziwe bwino matendawo komanso kuti mupeze chithandizo choyenera.
• Ngakhale kuti chithandizo sichingathe kuchiza matendawa kwathunthu, zizindikiro zake zimatha kulamulidwa bwino .
• Musanyalanyaze zizindikiro, chifukwa zingayambitse kuwonongeka kwa impso ngati sizikuchiritsidwa.

Ngati muli ndi mafunso ena okhudza izi, musazengereze kulankhula ndi dokotala wa banja lanu kapena katswiri wa nyamakazi. Adzakuthandizani kwambiri.

Ma SAID, matenda a malungo nthawi ndi nthawi, malungo obwerezabwereza, matenda otupa okha, malungo, malungo mwa ana, matenda a majini