Kodi pali kusintha kulikonse m'thupi lanu? Tiyeni tidziwe za Prolactinoma (Prolactinoma)

Kodi msambo wanu wayamba kusakhazikika mwadzidzidzi? Kapena pali kutuluka magazi oyera ngati mkaka m'mabere mwanu, ngakhale mutakhala kuti simuli ndi pakati kapena simukuyamwitsa? Ngati ndinu mwamuna, kodi mwakumana ndi kuchepa kwa chilakolako chogonana kapena mavuto ena? Chifukwa cha zinthuzi chikhoza kukhala chinthu chomwe simunaganizirepo. Lero tikulankhula za vuto lotere, lomwe ndi matenda otchedwa Prolactinoma.

Mwachidule, kodi Prolactinoma ndi chiyani?

Prolactinoma ndi chotupa chomwe chimakula mu gland kakang'ono komwe kali pafupi kwambiri ndi ubongo wathu, pansi pa ubongo, kotchedwa pituitary gland. Tsopano, musachite mantha tikanena kuti "chotupa." Ichi ndi chotupa chosakhala khansa (chosaopsa). Izi zikutanthauza kuti si chotupa chomwe chimapha chomwe chimafalikira mthupi lonse ngati khansa. Ichi ndi chotupa chofala kwambiri chomwe chimakula mu gland ya pituitary.

Chotupachi chimapangitsa thupi lathu kupanga mahomoni ambiri otchedwa prolactin kuposa momwe liyenera kukhalira. Kawirikawiri, mahomoni a prolactin awa ndi ofunikira kwambiri pakukula kwa mawere a akazi komanso kupanga mkaka woyamwitsa (kuyamwitsa). Koma mahomoni awa akachuluka, vuto lotchedwa hyperprolactinemia limachitika, lingayambitse mavuto osiyanasiyana kwa akazi ndi amuna.

Kodi pali mitundu ya prolactinoma?

Inde, mtedza uwu umagawidwa m'magulu awiri akuluakulu kutengera kukula kwawo. Kuti mumvetse izi, onani tebulo ili m'munsimu.

Kodi zizindikiro za izi ndi ziti?

Zizindikiro zimadalira kuchuluka kwa mahomoni a prolactin omwe amapangidwa komanso kukula kwa chotupacho. Tiyeni tiwone zizindikirozi.

Azimayi amatha kuzindikira vutoli msanga chifukwa cha zizindikiro monga kusintha kwa nthawi yawo ya msambo kapena kutuluka magazi m'mawere. Komabe, anthu omwe amamwa mapiritsi oletsa kubereka kapena mankhwala ena a mahomoni sangakumane ndi zizindikirozi. Komanso, zizindikiro zimatha kuchedwa kwa akazi ndi amuna omwe adasiya kusamba, zomwe zingachedwetse kuzindikira matendawa.

Kodi chifukwa chake ndi chiyani?

Ndipotu, ofufuza sanapezebe chifukwa chenicheni cha Prolactinoma. Nthawi zambiri, imachitika pang'onopang'ono, popanda chifukwa chenicheni. Komabe, matenda ena a majini angapangitse kuti chiopsezocho chiwonjezeke.

• "Multiple endocrine neoplasia (MEN) mtundu 1"
• `Mtundu wa ANTHU 4`
• ``Familial isolated pituitary adenomas (FIPA)''

Kodi mwapeza bwanji izi, Dokotala?

Dokotala wanu adzayamba kaye wayang'ana mosamala zizindikiro zanu ndi mbiri yanu yachipatala. Kenako, adzakuyezani thupi. Kenako angakulangizeni mayeso angapo kuti atsimikizire matendawa.

• Kuyezetsa magazi a prolactin: Iyi ndi njira yodziwira matenda ofala kwambiri. Ngati njira yodziwira matendawa ikutsimikizira kuti kuchuluka kwa prolactin m'magazi anu kuli kokwera kwambiri kuposa masiku onse, mudzatumizidwa kukayezetsa magazi ena kuti muwone ngati muli ndi chotupa.
• MRI kapena CT scan: Ma scan amenewa amatha kusonyeza ngati chotupa cha pituitary chilipo, ndipo ngati chilipo, kukula kwake. Madokotala nthawi zambiri amalimbikitsa kuti ayesedwe ndi MRI scan.
• Kuyezetsa magazi mulingo wa testosterone: Ngati ndinu mwamuna, dokotala wanu angakulangizeninso kuti muyeze mulingo wa testosterone m'thupi lanu.

Ngati matendawa atsimikizika, mungalimbikitsidwe kuti mufufuze kuchuluka kwa mahomoni ena mu pituitary gland ndikuyesedwa maso ndi dokotala wa maso kuti muwone ngati maso anu akhudzidwa ngati muli ndi chotupa chachikulu (macroprolactinoma).

Kodi mankhwala ochizira izi ndi otani?

Nkhani yabwino ndi yakuti pali mankhwala othandiza kwambiri pa izi. Nthawi zambiri, vutoli limatha kuthetsedwa ndi mankhwala.

Mankhwala (mankhwala)

Madokotala nthawi zambiri amapereka mankhwala otchedwa dopamine agonists. Mankhwalawa amatha kuchepetsa prolactinoma ndikubwezeretsa kuchuluka kwa prolactin m'thupi.

• Cabergoline ndi Bromocriptine: Awa ndi mankhwala awiri akuluakulu omwe amagwiritsidwa ntchito. Mwa awa, cabergoline ndiye chisankho choyamba cha madokotala chifukwa ndi yothandiza kwambiri ndipo ili ndi zotsatirapo zochepa.
• Zotsatirapo zake: Mankhwalawa angayambitse zotsatirapo zazing'ono monga nseru, kusanza, ndi chizungulire.
• Nthawi ya chithandizo: Kuti chotupacho chisabwererenso, muyenera kumwa mankhwalawa mosalekeza kwa zaka zosachepera ziwiri . Pakatha zaka ziwiri, ngati kuchuluka kwa prolactin kwanu kwabwerera mwakale ndipo chotupacho sichikuonekanso pa scan, dokotala wanu adzachepetsa pang'onopang'ono mlingo wa mankhwalawo ndipo pamapeto pake adzasiya.

Opaleshoni

Opaleshoni siifunikira kawirikawiri. Izi zimachitika pazochitika ngati izi:

• Ngati mankhwalawo ali ndi zotsatirapo zoyipa kwambiri.
• Ngati chotupacho sichikuchepa ndi mankhwala.
• Ngati mankhwalawa akugwirizana ndi mankhwala ena omwe mukumwa.
• Ngati muli ndi chotupa chachikulu ndipo muyenera kuchichotsa musanayese kutenga mimba.

Pali mitundu iwiri ya opaleshoni.

1. Opaleshoni ya transsphenoidal: Iyi ndi opaleshoni yofala kwambiri. Pano, chotupacho chimachotsedwa kudzera mu kabowo kakang'ono mkati mwa mphuno kapena pansi pa mlomo wapamwamba.

2. Opaleshoni ya transcranial: Ngati chotupacho ndi chachikulu kwambiri, chotupacho chimachotsedwa kudzera m'kabowo kakang'ono m'chigaza.

Chithandizo cha radiation

Chithandizo cha radiation ndi njira yachitatu pamene khansa siilandira mankhwala kapena opaleshoni. Ichinso ndi chithandizo chosowa kwambiri.

Kodi chiyembekezo cha matendawa ndi chotani?

Chiyembekezo cha prolactinoma ndi chabwino kwambiri. Ndi chithandizo chamankhwala, anthu anayi mwa asanu omwe ali ndi zotupa zazing'ono amatha kukhala ndi prolactin wabwinobwino ndipo chotupacho chikhoza kuchepa.

Opaleshoni nthawi zambiri imapambana. Akachitidwa ndi dokotala wodziwa bwino ntchito yake, kuchuluka kwa prolactin kumatha kubwezeretsedwanso m'thupi mwa anthu pafupifupi 90% omwe ali ndi zotupa zazing'ono ndi 50% omwe ali ndi zotupa zazikulu.