Tiyeni tiphunzire za mapiritsi a Sirolimus. Kodi mwapatsidwanso mankhwala awa?

Kodi dokotala wakupatsani piritsi lotchedwa `Sirolimus` kapena munthu wina amene mumamudziwa? Ngati ndi choncho, ndikofunikira kudziwa bwino lomwe kuti mankhwalawa ndi otani. Chifukwa chakuti awa si mankhwala a chimfine kapena fuluwenza, ndi mankhwala omwe amafunika kugwiritsidwa ntchito mosamala kwambiri, ndipo ali ndi zotsatirapo zake komanso zoopsa zake. Tiyeni tikambirane za izi mwatsatanetsatane, sichoncho?

Kodi mankhwala awa otchedwa `Sirolimus` ndi chiyani?

Mwachidule, Sirolimus ndi mankhwala omwe amachepetsa ntchito ya chitetezo cha mthupi lanu. Tangoganizirani, munthu akalandira chiwalo chatsopano monga impso kapena chiwindi, chitetezo cha mthupi chimayesa kukana chiwalo chatsopanochi. Chimaona ngati mdani wafika. Pamenepo ndi pomwe mankhwala ngati Sirolimus amakhala othandiza. Ndiko kuti, amagwiritsidwa ntchito makamaka kuletsa thupi kukana chiwalo chatsopano.

Amagwiritsidwanso ntchito pochiza matenda osowa kwambiri a m'mapapo otchedwa lymphangioleiomyomatosis (LAM). Amapezeka kwambiri pansi pa dzina lakuti Rapamune. Komabe, nthawi zina dokotala wanu angakupatseni mankhwalawa pazifukwa zina. Choncho ngati muli ndi mafunso, ndi bwino kufunsa dokotala wanu kapena wamankhwala.

Kodi muyenera kuuza chiyani gulu lanu lachipatala musanagwiritse ntchito mankhwalawa?

Iyi ndi mfundo yofunika kwambiri. Musanayambe kumwa Sirolimus, muyenera kuuza dokotala wanu za thanzi lanu lonse. Izi zili choncho chifukwa matenda ena sangagwirizane ndi mankhwalawa, kapena mungafunike kuwasamala kwambiri.

Ngati muli ndi zinthu izi, nenani motsimikiza kuti:

• Ngati muli ndi matenda a shuga (Diabetes Mellitus) .
• Ngati muli ndi mbiri ya matenda a mtima kapena kulephera kwa mtima .
• Ngati muli ndi cholesterol yambiri kapena triglycerides m'magazi mwanu.
• Ngati muli ndi matenda (monga malungo, chimfine, kapena matenda a mkodzo).
• Ngati muli ndi matenda a chiwindi .
• Ngati mudakumanapo ndi vuto la ziwengo kapena vuto lachilendo la sirolimus, perekani mankhwala ena, zakudya, utoto, kapena zosungira.
• Ngati muli ndi pakati kapena mukufuna kutenga mimba .
• Ngati ndinu mayi woyamwitsa .

Dokotala adzatha kukuthandizani m'njira yoyenera kwambiri akamakuuzani zinthuzi poyera.

Kodi mumagwiritsa ntchito bwanji mankhwalawa molondola?

Ndikofunikira kwambiri kutsatira malangizo enieni ogwiritsira ntchito mankhwalawa.

• Piritsi ili liyenera kumwedwa ndi kapu ya madzi.
• Musaswe, kuphwanya, kapena kutafuna piritsi. Mezani lonse.
• Gwiritsani ntchito mankhwalawo monga momwe zalembedwera pa chizindikiro cha mankhwala.
• Ngati mumwa mankhwalawa pamodzi ndi chakudya, imwani pamodzi ndi chakudya tsiku lililonse. Izi zikutanthauza kuti, musasinthe pakati pa kumwa musanadye tsiku lina ndi mutadya tsiku lotsatira. Imwani mofanana.
• Musamwe mankhwalawa pamodzi ndi madzi a mphesa. Madzi a mphesa angakhudze momwe mankhwalawa amagwirira ntchito.
• Ngati mukumwanso mankhwala a `cyclosporine`, muyenera kumwa mankhwala a `Sirolimus` awa osachepera maola 4 mutatha kumwa `cyclosporine`.
• Yesetsani kumwa mankhwala anu nthawi yomweyo tsiku lililonse, nthawi yomweyo tsiku lililonse . Pamenepo ndi pamene mudzapindula kwambiri ndi mankhwalawo.
• Musamwe mankhwala ochulukirapo kuposa momwe dokotala wanenera, kapena siyani kumwa mankhwalawa msanga. Musasiye kumwa mankhwala popanda upangiri wa dokotala.

Ngati mupatsa ana mankhwalawa:

Mankhwalawa amatha kuperekedwa kwa ana azaka 13 nthawi zina. Komabe, njira zina zodzitetezera ziyenera kutsatiridwa. Chifukwa chake, ngati mukupereka mankhwalawa kwa mwana wanu, kambiranani mosamala ndi dokotala wanu wa ana ndipo funsani upangiri.

Mukalandira mankhwalawa kuchokera ku pharmacy, mudzalandira `MedGuide` (Chitsogozo cha Mankhwala) . Mudzalandira izi pamodzi ndi mankhwala aliwonse omwe mumalandira komanso nthawi iliyonse mukalandira mankhwala owonjezera. Nthawi zonse werengani malangizo mosamala. Ali ndi mfundo zambiri zofunika.

Kuchuluka kwa mankhwala:

Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, imbani malo owongolera poizoni kapena chipinda chodzidzimutsa kuchipatala nthawi yomweyo .

Chofunika: Mankhwalawa ndi a inu nokha. Musagawire ena mankhwala anu, ngakhale atakhala ndi zizindikiro zomwezo zomwe muli nazo.

Kodi mumatani ngati mwaphonya nthawi yokumana ndi dokotala?

Ngati mwaphonya mlingo, imwani mwamsanga mukangokumbukira. Komabe, ngati nthawi yatsala pang'ono yoti mutenge mlingo wotsatira, thawani mlingo womwe mwaphonya ndikumwa mlingo wotsatira monga momwe munakonzera. Musamwe milingo iwiri nthawi imodzi. Komanso, ngati mwaphonya mlingo kapena kusanza mutamwa mankhwala, imbani dokotala wanu kapena katswiri wa zaumoyo kuti akupatseni malangizo.

Ndi zinthu zina ziti zomwe zingagwirizane ndi mankhwalawa?

Ichi ndi chinthu choyenera kusamala nacho kwambiri. Sirolimus ndi mankhwala omwe amatha kuyanjana ndi mankhwala ena, zakudya, ndi zowonjezera. Kuyanjana kumeneku kungasinthe momwe Sirolimus imagwirira ntchito, kuwonjezera zotsatirapo zake, kapena kusintha momwe mankhwala ena omwe mukumwa amagwirira ntchito.

Musamwe Sirolimus ndi mankhwala awa:

• Mitundu ina ya maantibayotiki: monga clarithromycin, erythromycin, ndi telithromycin.
• Madzi a mphesa (ndanena kale izi, ndizofunikira kwambiri!)
• Mankhwala a matenda a bowa: monga `itraconazole`, `ketoconazole`, `posaconazole`, `voriconazole`.
• `Mifepristone (mifepristone), RU-486`
• `rifabutin`, `rifampin`

Mankhwalawa angagwirizanenso ndi mankhwala otsatirawa:

• `Boceprevir`
• 'Bromocriptine'
• `Carbamazepine`
• " Cimetidine "
• `Cisapride`
• 'Clotrimazole'
• `Cyclosporine` (kuwonjezera pa nthawi yomwe yatchulidwa, pakhoza kukhala kuyanjana kwina)
• `Danazol`
• `Diltiazem`
• `Fluconazole`
• `Indinavir`
• 'Metoclopramide'
• `Nicardipine`
• `Phenobarbital`
• `Phenytoin`
• Rifapentine
• `Ritonavir (ritonavir)`
• `St. John's wort` (iyi ndi therere)
• `Telaprevir`
• `Troleandomycin`
• Katemera
• `Verapamil`

Mndandandawu sukuphatikizapo zinthu zonse zomwe mumagwiritsa ntchito. Choncho, uzani dokotala wanu za mankhwala onse omwe mumamwa (omwe amalembedwa ndi dokotala, omwe amagulitsidwa pamtengo wotsika, omwe amagulitsidwa ndi mankhwala ochokera ku zitsamba, mavitamini, zakudya zowonjezera), ngati mumasuta fodya, mumamwa mowa, kapena mumagwiritsa ntchito mankhwala ena. Zinthu zina zingasokoneze mankhwala anu.

Ndiyenera kusamala ndi chiyani ndikamamwa mankhwalawa?

Dokotala wanu nthawi zonse amafufuza thanzi lanu pamene mukumwa Sirolimus.

• Ndikofunikira kuonana ndi dokotala nthawi zonse ndikuyesedwa magazi . Izi zithandiza dokotala kudziwa momwe mankhwalawo akukukhudzirani komanso ngati mlingo wake ndi woyenera kwa inu.
• Mankhwalawa angawonjezere kuchuluka kwa mafuta m'thupi kapena cholesterol m'thupi lanu. Ngati izi zitachitika, mungafunike kulandira chithandizo china.
• Ngati mukumwa mankhwala awa, uzani dokotala wanu nthawi yomweyo. Musamadzipatse mankhwala okha. Mankhwalawa angachepetse mphamvu ya thupi lanu yolimbana ndi matenda.
• Mankhwalawa angawonjezere shuga m'magazi mwanu. Ngati muli ndi matenda a shuga, funsani dokotala wanu ngati mukufuna kusintha zakudya kapena mankhwala anu.
• Mankhwalawa angakulitse pang'ono chiopsezo chanu chotenga mitundu ina ya khansa. Lankhulani ndi dokotala wanu za izi. Musachite mantha, koma ndikofunikira kudziwa.
• Chifukwa cha mankhwala awaKhungu lanu likhoza kukhala losavuta kumva kuwala kwa dzuwa. Choncho, pewani kupsa ndi dzuwa momwe mungathere. Ngati mutuluka panja, valani zovala zophimba khungu lanu, gwiritsani ntchito mafuta oteteza ku dzuwa, ndipo pewani nyali za dzuwa kapena malo opaka utoto.
• Azimayi a msinkhu wobereka ayenera kugwiritsa ntchito njira yothandiza kwambiri yolerera ana asanayambe kumwa mankhwalawa, akamamwa, komanso kwa milungu 12 atasiya kumwa mankhwalawa.

Kodi zotsatirapo zake zingakhale zotani chifukwa cha mankhwalawa?

Monga mankhwala ena aliwonse, Sirolimus ingayambitse zotsatira zina. Si aliyense amene amalandira, koma ndibwino kudziwa za izo.

Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala kapena katswiri wa zaumoyo nthawi yomweyo:

• Matenda a ziwengo: kutupa pakhungu, kuyabwa kapena ziphuphu, kutupa kwa nkhope, milomo kapena lilime.
• Kuvuta kupuma.
• Kuzizira, malungo, kupweteka pakhosi. (Izi zitha kukhala zizindikiro za matenda)
• Mkodzo wakuda.
• Kugunda kwa mtima mwachangu komanso kosasinthasintha.
• Kumva chizungulire kapena mutu wopepuka.
• Kuthamanga kwa magazi.
• Kuoneka kwa mawanga ofiira pakhungu.
• Zizindikiro za shuga wambiri m'magazi: Kumva ludzu kapena njala kwambiri kuposa masiku onse, kufunikira kukodza pafupipafupi. Muthanso kutopa kwambiri kapena kusawona bwino.
• Kutupa, kusunga madzi m'thupi.
• Kuvuta kukodza.
• Kutuluka magazi kapena mabala osazolowereka.
• Kumva kufooka kwambiri.

Zotsatirapo zomwe nthawi zambiri sizifuna thandizo la dokotala, koma ziyenera kufotokozedwa kwa dokotala ngati zikupitirira kapena zikuvutitsa:

• Kupweteka kwa thupi, kupweteka.
• Ziphuphu.
• Kutsegula m'mimba (kupweteka m'mimba).
• Kusanza, kusanza.
• Kusasangalala m'mimba.
• Kugwedezeka.
• Kusowa tulo.

Mndandandawu sungakhale ndi zotsatirapo zonse zoyipa. Ngati mukukumana ndi zizindikiro zachilendo, funsani upangiri kwa dokotala. Muthanso kunena za zotsatirapo zoyipa ku FDA pa 1-800-FDA-1088.

Kodi ndiyenera kusunga kuti mankhwala anga?

• Sungani pamalo omwe ana sangafikire. Izi ndizofunikira kwambiri.
• Sungani kutentha kwa chipinda (20 mpaka 25 digiri Celsius / 68 mpaka 77 digiri Fahrenheit). Tetezani ku kutentha kwambiri kapena kuzizira.
• Tayani mankhwala omwe atha ntchito. Musasunge mankhwala omwe sanagwiritsidwe ntchito akatha ntchito.

Uthenga Womaliza Wopita Nawo Kunyumba

Chabwino, takambirana zambiri za Sirolimus, sichoncho? Kumbukirani, chofunika kwambiri ndikugwiritsa ntchito mankhwalawa monga momwe dokotala wanu wanenera.

Mwachidule:

* Imwani mankhwalawo monga momwe dokotala wanu wanenera, panthawi yoyenera, komanso muyeso woyenera.

* Muuzeni dokotala wanu za thanzi lanu lonse komanso mankhwala ena onse ndi zowonjezera zomwe mukumwa.

* Musamwe mankhwalawa pamodzi ndi madzi a mphesa.

* Dziwani zotsatirapo zake, ndipo ngati muwona china chake chachilendo, uzani dokotala wanu nthawi yomweyo.

* Werengani `MedGuide` yomwe mwapatsidwa mosamala.

* Musapatse ena mankhwala anu.

Kugwiritsa ntchito mankhwalawa kungawoneke ngati kovuta pang'ono. Koma musadandaule. Ngati muli ndi mafunso kapena nkhawa, funsani dokotala wanu kapena wamankhwala. Ali okonzeka kukuthandizani. Umoyo wanu ndiye chinthu chofunikira kwambiri kwa iwo!

Sirolimus , Sirolimus, chitetezo chamthupi, kuikidwa ziwalo, LAM, Rapamune, zotsatira zoyipa za mankhwala, kuyanjana kwa mankhwala