Kodi mukufuna kudziwa zambiri za mankhwala a SNRI? (Serotonin ndi Norepinephrine Reuptake Inhibitors)

Kodi dokotala wakupatsani mankhwala otchedwa SNRI chifukwa cha kuvutika maganizo kapena nkhawa zomwe zimapitirira? Mwina mnzanu wina akugwiritsa ntchito mankhwalawa. Mwina munachita mantha pang'ono mutamva dzinali. Mwina muli ndi mafunso ambiri m'maganizo mwanu monga, "Kodi mankhwalawa ndi chiyani? Kodi awa ndi abwino kwa thupi?" Lero, tiyeni tikambirane za mtundu uwu wa mankhwala otchedwa SNRI mosavuta, ngati kuti mukulankhula ndi mnzanu.

Mwachidule, kodi ma SNRI amenewa ndi chiyani?

Tanthauzo lonse la SNRI ndi Serotonin ndi Norepinephrine Reuptake Inhibitors . Chabwino, dzinali likumveka lovuta pang'ono, sichoncho? Tiyeni tilifotokoze mwachidule.

Mu ubongo wathu, muli mankhwala apadera omwe amalamulira zinthu zambiri, kuphatikizapo malingaliro athu, malingaliro athu, tulo, ndi chilakolako chathu. Timatcha awa kuti "Neurotransmitters." Monga positiman, amithenga awa amanyamula mauthenga kuchokera mbali imodzi ya ubongo kupita ku ina.

Awiri mwa atumiki awa ndi serotonin ndi norepinephrine .

• Serotonin ndi yofunika kwambiri pazinthu monga momwe timamvera, kugona, komanso kugaya chakudya. Pamene serotonin ili pamwamba, timasangalala komanso timamasuka.
• Norepinephrine imatithandiza kukhalabe okhazikika, amphamvu, komanso otanganidwa.

Chomwe chimachitika nthawi zambiri n'chakuti akamaliza kupereka uthenga wawo, maselo a ubongo amawatenganso. Izi zimatchedwa ``Reuptake.'' Monga momwe wotumiza makalata amabwerera ku positi ofesi akamaliza kupereka kalata.

Komabe, mwa anthu omwe ali ndi matenda monga kupsinjika maganizo kapena nkhawa, ntchito ya serotonin ndi norepinephrine messengers iyi ingachepe pang'ono muubongo.

Apa ndi pomwe mankhwala a SNRI amalowa. Zimene mankhwala amenewa amachita ndikuletsa kwakanthawi kuti anthu otumiza uthengawo asatengedwenso. Zili ngati kuuza munthu wotumiza uthenga kuti "dikirani pang'ono ndikupereka mauthenga ena angapo." Kenako anthu abwinowa (serotonin ndi norepinephrine) amakhala muubongo nthawi yayitali ndikuchita ntchito yawo yabwino. Izi zimayamba kutithandiza kukhala ndi maganizo abwino, kuchepetsa nkhawa, komanso kuwonjezera mphamvu zathu.

Kodi mankhwala a SNRI amagwiritsidwa ntchito pa matenda otani?

Ngakhale kuti mankhwala amenewa amaperekedwa makamaka pa matenda amisala, madokotala amawaperekanso pa matenda ena angapo amthupi. Tiyeni tiwone zomwe zili.

Mwina mukudabwa kuti "kugwiritsa ntchito mankhwala osakhala ndi chizindikiro" kumatanthauza chiyani. Zimatanthauza kuti dokotala, kutengera chidziwitso chake cha zachipatala komanso zomwe adakumana nazo, amalimbikitsa mankhwala a matenda ena, kuwonjezera pa matenda akuluakulu omwe amavomerezedwa. Izi zimachitika kawirikawiri.

Kodi mitundu yodziwika bwino ya SNRIs ku Sri Lanka ndi iti?

Pali mitundu ingapo ya mankhwala a SNRI. Dokotala wanu adzakusankhirani mankhwala oyenera kutengera matenda anu, zaka zanu, ndi matenda ena.

• Venlafaxine (monga dzina la kampani ya Effexor®)
• Duloxetine (monga dzina lodziwika bwino la Cymbalta®)
• Desvenlafaxine (dzina la Pristiq®)
• Milnacipran (dzina la Savella®)
• Levomilnacipran (monga dzina la Fetzima®)

Mankhwala omwe mudalandira akhoza kukhala ndi chimodzi mwa zomwe zili pamwambapa.

Kodi zotsatirapo zake zingakhale zotani pogwiritsa ntchito mankhwalawa?

Monga mankhwala ena onse, mankhwalawa akhoza kukhala ndi zotsatirapo zazing'ono. Koma kwa anthu ambiri, izi si zoopsa kwenikweni. Nthawi zambiri zimachitika m'masabata oyamba kumwa mankhwalawo kenako zimatha thupi lanu likayamba kuzolowera mankhwalawo.

Zochitika zapadera zoopsa zomwe muyenera kuziganizira

Ngakhale kuti SNRI nthawi zambiri ndi mankhwala otetezeka, ndi bwino kudziwa zoopsa zina zazikulu, ngakhale kuti sizingachitike kawirikawiri.

1. Matenda a Serotonin

Ichi ndi chinthu chofunika kwambiri choyenera kusamala nacho. Pamene SNRIs ndi mankhwala ena omwe amakhudza kuchuluka kwa serotonin atengedwa pamodzi, kuchuluka kwa serotonin muubongo kumatha kukwera mosafunikira. Ichi ndi vuto lalikulu lachipatala .

• Zizindikiro: Kusokonezeka maganizo, kugunda kwa mtima mofulumira, kutentha thupi kwambiri, minofu yolimba kapena yogunda, komanso thukuta kwambiri.
• Zoyenera kuchita: Ngati inuyo kapena munthu amene mumamudziwa mwadzidzidzi ayamba kudwala matendawa, pitani kwa dokotala nthawi yomweyo kapena pitani ku Dipatimenti Yothandiza Pangozi (ETU) ya chipatala chapafupi.

2. Zizindikiro zomwe zimachitika mukasiya kumwa mankhwala (Antidepressant Discontinuation Syndrome)

Ngati mumwa mankhwalawa kwa nthawi yayitali ndikusiya mwadzidzidzi, thupi lanu likhoza kumva kupweteka chifukwa cha mankhwalawa.

• Makhalidwe:Chizungulire, mutu, nseru, kupweteka kwa thupi (monga kutentha thupi), komanso nkhawa yaikulu.
• Kupewa: Musasiye kumwa mankhwala popanda kufunsa dokotala wanu. Ngati mukufuna kusiya, dokotala wanu adzachepetsa pang'onopang'ono mlingo kwa mwezi umodzi kapena iwiri, adzalola thupi lanu kusintha, kenako n'kukuwonetsani momwe mungasiyire mosamala.

3. Maganizo ofuna kudzipha

Nkhaniyi ndi yovuta kwambiri, koma ndi nkhani yofunika kukambirana. Kafukufuku wapeza kuti pali chiopsezo chochepa kwambiri chowonjezeka cha malingaliro ofuna kudzipha, makamaka kwa achinyamata osakwana zaka 25 , m'masabata oyamba kugwiritsa ntchito mankhwalawa.

• Chofunika: Ngati muli ndi maganizo awa, chonde musavutike nokha. Si vuto lanu, mwina ndi zotsatirapo za mankhwala. Uzani dokotala wanu nthawi yomweyo. Uzani wachibale wanu kapena mnzanu amene mumamukhulupirira. Kupempha thandizo kumalimbitsa mtima.

Zinthu zina zofunika kuziganizira mukamamwa SNRIs

Kumwa mowa

Ndi bwino kupewa kumwa mowa mukamamwa mankhwala ochepetsa nkhawa monga SNRIs. Mowa umathandizanso kuchepetsa nkhawa m'mitsempha. Chifukwa chake, ungasokoneze kugwira ntchito kwa mankhwalawo. Nthawi zina mowa ungapangitse zizindikiro za kuvutika maganizo kukhala zovuta kwambiri.

Mankhwala ena

Ngati mukumwa SNRI, uzani dokotala wanu za mankhwala ena onse omwe mukumwa (mankhwala ochepetsa ululu, mankhwala a chifuwa, mavitamini, ngakhale mankhwala azitsamba). Mankhwala ena amatha kusokonezana ndi SNRI.

• Mankhwala ochepetsa ululu monga NSAIDs (monga Ibuprofen, Diclofenac)
• Mankhwala omwe amaletsa magazi kuundana (monga Aspirin, Clopidogrel)
• Triptans ndi mankhwala a mutu waching'alang'ala.
• Zinthu zochokera ku zitsamba monga St. John's Wort

Mimba ndi kuyamwitsa

Ngati mukukonzekera kutenga pakati, muli kale ndi pakati, kapena mukuyamwitsa, muyenera kulankhula ndi dokotala wanu za kugwiritsa ntchito mankhwalawa. Ma SNRI ena amatha kukhudza mwana m'mimba. Komanso, kusiya kumwa mankhwala mwadzidzidzi kungakhale kovulaza mayi. Dokotala wanu angakuthandizeni kusankha njira yabwino kwambiri kwa inu ndi mwana wanu.

Kodi mankhwalawo amatenga nthawi yayitali bwanji kuti agwire ntchito?

Funso limene anthu ambiri amafunsa ndi ili. Mankhwala a SNRI si mankhwala omwe amagwira ntchito nthawi yomweyo monga Panadol. Zimatenga nthawi kuti mankhwala a muubongo agwire bwino ntchito.

• Anthu ambiri adzawona kusintha pang'ono (kupita patsogolo) kwa zizindikiro mkati mwa masabata 4 mpaka 6 .
• Zingatenge pakati pa milungu 9 ndi 12 (miyezi iwiri kapena itatu) kuti anthu ena apindule mokwanira ndi mankhwalawa.

Choncho, musasiye kumwa mankhwala chifukwa chakuti simukumva kusintha kwakukulu m'masabata oyamba.Khalani oleza mtima. Ngati simukumvabe kusintha kulikonse pambuyo pa nthawi imeneyo, lankhulani ndi dokotala wanu kachiwiri. Iye akhoza kusintha mlingo kapena kukusinthani ku mankhwala ena.