Zadzidzidzi zomwe zimabwera ndi chithandizo cha khansa: Tiyeni tiphunzire za Tumor Lysis Syndrome!

Kukhala ndi khansa ndi vuto lalikulu. Ngakhale kuti mankhwala monga chemotherapy angathandize kuwononga maselo a khansa, nthawi zina mankhwala amenewo angayambitse mavuto osayembekezereka. Lero, tikambirana za ngozi yomwe imafuna chisamaliro chachangu komanso yomwe ingakhale yoopsa . Izi zimatchedwa Tumor Lysis Syndrome.

Kodi matenda a Tumor Lysis ndi chiyani? Tiyeni timvetse mosavuta.

Mwachidule, Tumor Lysis Syndrome ndi gulu la matenda oopsa omwe amapezeka pamene maselo ambiri a khansa amafa nthawi imodzi ndipo zomwe zili m'maselowo zimatulutsidwa m'magazi. Tangoganizirani, vutoli lingachitike mkati mwa maola ochepa kuchokera pamene chithandizo cha khansa chayamba. Likhoza kukula mofulumira kwambiri ndikukhala vuto lomwe limafuna chithandizo chadzidzidzi. Chifukwa chake, madokotala nthawi zonse amakhala akuyang'anitsitsa izi.

Koma pali nkhani yabwino. Madokotala ali ndi njira zopewera Tumor Lysis Syndrome . Amachita izi pozindikira omwe ali pachiwopsezo chachikulu ndikuchitapo kanthu kuti achepetse chiopsezocho.

Kodi chimachitika ndi chiyani ku matupi athu mu mkhalidwe uwu?

Maselo a khansa akakumana ndi mavuto, makamaka chifukwa cha mankhwala monga chemotherapy, amawonongeka. Kenako, mankhwala ndi poizoni omwe ali mkati mwa maselowo amasonkhana mwadzidzidzi m'magazi ambiri. Vuto limayamba pamene thupi lathu silingathe kuchotsa izi mwachangu. Matenda a chotupa ichi amatha kukhudza mtima wathu, impso, ndi minofu. Tiyeni tiwone zotsatira zake:

• Hyperuricemia - Izi zikutanthauza kuchuluka kwa uric acid m'magazi: Pamene uric acid m'magazi ikuwonjezeka, imatha kusungidwa mu impso, zomwe zimayambitsa kusokonekera kwa impso komanso kulephera kwa impso. Taganizirani izi ngati kutsekeka kwa chitoliro cha madzi.
• Hyperphosphatemia - kutanthauza kuchuluka kwa phosphorous: Kuchuluka kwa phosphorous m'magazi kumasokonezanso ntchito ya impso.
• Hyperkalemia - Izi zikutanthauza kuchuluka kwa potaziyamu: Pamene kuchuluka kwa potaziyamu kuli kokwera, mungakumane ndi zizindikiro monga nseru, kusanza, ndi kutsegula m'mimba. Sikuti zokhazo, komanso kugunda kwa mtima wanu kungasinthe, zomwe zimayambitsa arrhythmias, komanso mwina matenda a mtima. Izi ndi zoopsa pang'ono, sichoncho?
• Uremia: Izi zimachitika impso zikasiya kusefa poizoni m'magazi. Uremia ingayambitse mavuto aakulu m'mafupa, minofu, mtima, ndi mitsempha yamagazi.
• Hypocalcemia - Kuchepa kwa calcium m'magazi: Kuchepa kwa calcium m'magazi kungayambitse kusintha kwa kagayidwe ka mtima, kupweteka kwa minofu, kusokonezeka, dzanzi ndi kumva kuwawa m'miyendo. Nthawi zina, ngakhale imfa chifukwa cha kulephera kwa mtima imachitika.

Chofunika kwambiri: Matenda a Tumor Lysis amapezeka pamene chimodzi kapena zingapo mwa izi zikugwirizana.

Kodi Matenda a Tumor Lysis ndi adzidzidzi?

Inde, ndithudi! Matenda a Tumor Lysis ndi vuto lachipatala lomwe limafuna chithandizo chadzidzidzi. Chifukwa chake, ndikofunikira kwambiri kudziwa izi.

Ndani angagwere mu vutoli?

Si aliyense amene amalandira chithandizo cha khansa amene amadwala Tumor Lysis Syndrome. Ngati mukulandira chithandizo cha khansa, ndi bwino kufunsa dokotala wanu za izi. Kawirikawiri, anthu omwe amalandira chithandizo cha chemotherapy cha mitundu iyi ya khansa ali pachiwopsezo chachikulu chotenga matendawa:

• Khansa ya m'magazi ya Lymphocytic
• Lymphoma Yopanda Ufulu wa Hodgkin, monga Burkitt Lymphoma ndi Diffuse Large B-cell Lymphoma
• Matenda a Myeloid Leukemia (AML)
• B-cell Acute Lymphoblastic Leukemia (ONSE)
• Khansa ya M'mapapo ya Maselo Ang'onoang'ono

Komanso, pali mitundu ina ya khansa yomwe, ikachiritsidwa, imakhala ndi chiopsezo chochepa chotenga matendawa. Koma sichinathe konse. Zitsanzo:

• Anaplastic Large Cell Lymphoma - Iyi ndi khansa yosowa kwambiri, yomwe ikukula pang'onopang'ono m'thupi.
• Matenda a Leukemia Osatha a Lymphocytic (CLL)
• Neuroblastoma
• Khansa ya m'mawere
• Sarcoma Yofewa ya Minofu
• Medulloblastoma
• Khansa ya Merkel Cell

Kodi zifukwa zina za Tumor Lysis Syndrome ndi ziti?

Madokotala amadziwa kuti anthu ena ali pachiwopsezo chachikulu chotenga matendawa. Kusamala kwapadera kumatengedwa musanapereke mankhwala a chemotherapy kwa anthu otere. Nazi zinthu zina zomwe zimawonjezera chiopsezo:

• Kukhala ndi maselo oyera ambiri m'magazi.
• Uric acid m'magazi ndi wokwera kale.
• Kukhala ndi mavuto a impso.
• Kuchepa kwa madzi m'thupi (Kusowa madzi m'thupi).
• Kukhala ndi khansa pa siteji yoopsa (Later-stage Cancer).
• Kukhala ndi zotupa zazikulu.

Kodi vutoli lingachitike popanda chemotherapy?

Inde, koma zimachitika kawirikawiri . Zikachitika, madokotala amatcha kuti Spontaneous Tumor Lysis Syndrome.

Kodi zizindikiro za Tumor Lysis Syndrome ndi ziti?

Zizindikiro zimenezi nthawi zambiri zimawonekera mkati mwa maola 12 mpaka 72 mutayamba kulandira mankhwala a chemotherapy. Izi ndi izi:

• Kusanza ndi kusanza.
• Kutsegula m'mimba.
• Kusintha kwa kuchuluka kwa mkodzo womwe mumatuluka (kungachuluke kapena kuchepa).
• Kufooka ndi Kutopa.
• Magazi mu mkodzo (hematuria).
• Matenda a khunyu, ndiko kuti, khunyu.
• Kupweteka kwa Minofu.
• Kusamvana.
• Kugunda kwa mtima kosakhazikika.
• Kuthamanga kwa magazi pang'ono (Hypotension).
• Kupweteka kwa Mafupa.

Ngati mukukumana ndi chimodzi mwa zizindikiro izi kapena zingapo pamene mukulandira chithandizo cha khansa, muyenera kudziwitsa dokotala nthawi yomweyo.

Nchifukwa chiyani matenda a Tumor Lysis amachitika?

Mwachidule, vutoli limachitika pamene chithandizo cha khansa chimapangitsa kuti maselo ambiri a khansa afe mwadzidzidzi komanso mwachangu. Zinthu zomwe zili mkati mwa maselo akufa (monga potaziyamu, phosphorous, ndi uric acid) zimasonkhana mwadzidzidzi m'magazi.

Kawirikawiri, impso zathu ndi zomwe zimasefa zinthu zosafunikirazi. Koma, maselo ambiri akamwalira nthawi imodzi, impso sizingathe kuchita izi. Zili ngati ngalande yotsekeka pamene zinyalala zambiri zimabwera nthawi imodzi. Kenako poizoniyu amayamba kusonkhana m'thupi.

Kodi madokotala amazindikira bwanji vutoli?

Cholinga chachikulu cha madokotala ndi kupewa Tumor Lysis Syndrome. Kuti achite izi, nthawi zonse amachita mayeso a magazi ndi mkodzo kuti atsimikizire kuti impso zanu zikugwira ntchito bwino komanso kuti poizoni akuchotsedwa m'thupi lanu.

Kodi mankhwala a Tumor Lysis Syndrome ndi ati?

Madokotala amayesa koyamba kupewa izi. Amachita izi pozindikira omwe ali pachiwopsezo chachikulu ndikutengera njira zapadera zowatetezera. Koma, ngati vutoli litachitika, chithandizo chimayamba nthawi yomweyo.

Zinthu zoti muchite kuti mupewe:

• Kuthira madzi m'thupi kudzera m'mitsempha (IV): Izi zimathandiza kusunga madzi okwanira m'thupi, kulimbikitsa kukodza, komanso kuthandiza kuchotsa poizoni m'thupi mwachangu.
• Kupereka mankhwala omwe amaletsa kuyika kwa makristalo a uric acid mu impso: Pali mankhwala ena omwe amathandiza kuchepetsa kuchuluka kwa uric acid m'thupi.

Chithandizo ngati vutoli lachitika:

• Kupereka mankhwala ochepetsa mphamvu ya mkodzo: Izi zimathandiza kuchotsa poizoni m'thupi mwachangu.
• GLISH: Kupereka mankhwala ochotsa potaziyamu ndi phosphorous yochulukirapo.
• Kupereka mankhwala omwe amasungunula makristalo a uric acid omwe apangidwa mu impso.
• Kuchotsa poizoni m'magazi: Ngati impso zanu sizikugwira ntchito bwino, mungafunike kuyeretsa magazi kuti muchotse poizoni m'magazi anu. Izi zili ngati kugwira ntchito kwa impso zanu mwadala.

Kodi matenda a Tumor Lysis angachiritsidwe?

Inde, ndithudi! Pafupifupi 90 peresenti ya anthu omwe ali ndi vutoli amachira. Chofunika kwambiri ndikupeza matendawa msanga ndikuyamba kulandira chithandizo msanga.

Kodi chimachitika ndi chiyani vutoli likachiritsidwa?

Matenda a Tumor Lysis angayambitse kuwonongeka kwina kwa impso zanu. Chifukwa chake, ngati muli ndi vutoli, ndikofunikira kwambiri kufunsa dokotala wanu ngati mukufuna chithandizo china kapena chisamaliro chapadera mpaka impso zanu zitachira.

Mankhwala a khansa akukwera tsiku ndi tsiku, zomwe zimatithandiza kuwononga maselo a khansa mwachangu. Komabe, nthawi zina, maselowa akamwalira, mankhwala ndi poizoni omwe amatulutsa amatha kuyambitsa matenda oopsa otchedwa Tumor Lysis Syndrome. Izi zitha kukhudza kwambiri mtima ndi impso.

Pomaliza, zomwe muyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Chithandizo cha khansa ndi chovuta. Panthawiyi, ndikofunikira kudziwa zadzidzidzi monga Tumor Lysis Syndrome. Ngati mukulandira chithandizo cha khansa, onetsetsani kuti mwafunsa dokotala wanu ngati muli pachiwopsezo cha vutoli. Adzakufotokozerani zoopsa zake ndipo adzachita zonse zomwe angathe kuti apewe kapena kuchiza vutoli ngati litachitika. Musanyalanyaze zizindikiro zilizonse, ndipo uzani dokotala nthawi yomweyo ngati muwona china chake chachilendo. Kusamalira thanzi lanu ndiye chinthu chofunikira kwambiri!

Matenda a khansa , chithandizo cha khansa, chemotherapy, matenda a impso, hyperkalemia, hyperuricemia, chithandizo chadzidzidzi chachipatala