Bisphosphonates: Reka twige kuri uyu muti ukomeza amagufwa yawe.

Ese umuganga wawe yakubwiye ko amagufwa yawe afite intege nke, bivuze ko ufite indwara yo kubura amagufwa, indwara yo kugabanya amagufwa? Ashobora kuba yarakubwiye gutangira gufata umuti witwa bisphosphonate. Iyo wumvise iri zina, ushobora kugira ubwoba gato, ukibaza uti "Uyu muti ni iki? Uzakora iki?" Ntutinye. Uyu munsi, tugiye kuvuga kuri ubu bwoko bw'umuti ushobora gufasha gukomeza amagufwa yawe mu buryo bworoshye cyane , mu buryo ushobora kumva.

Mu magambo make, ibi bisphosphonates ni iki?

Bisphosphonates ni ubwoko bukomeye bw'imiti ikoreshwa mu kuvura indwara ya osteoporosis. Tekereza ko amagufwa yawe agenda acika intege uko igihe kigenda gihita, nk'igiti cyariwe n'udukoko. Hanyuma, ndetse no kugwa gato byongera ibyago byo kuvunika amagufwa yawe. Osteoporosis ni yo ndwara. Bityo, bisphosphonates zihagarika amagufwa yawe gukomeza gucika intege, bigatuma akomera, kandi zikagabanya ibyago byo kuvunika.

Abaganga batanga uyu muti atari uwo kuvura indwara ya osteoporosis gusa, ahubwo no ku zindi ndwara nyinshi zigira ingaruka ku bucucike bw'amagufwa, ndetse no mu bihe bimwe na bimwe by'umusemburo wa kalisiyumu mu maraso udasanzwe (hypercalcemia).

Ese iyi miti irahari? Reka turebe.

Yego, hari ubwoko bubiri bwa bisphosphonates.

1. Bisphosphonates zo mu kanwa

2. Gutera inshinge mu mitsi (IV bisphosphonates)

Muganga azasuzuma indwara yawe maze ahitemo ubwoko bukubereye.

Ni ibihe bibazo bikoreshwa muri bisphosphonates?

Uyu muti wemewe cyane cyane kuvura indwara zikurikira:

• Kurwara indwara yo gucika intege kw'amagufwa (osteoporosis) ku bagore bamaze gucura.
• Indwara yo gucika intege kw'amagufwa mu bagabo.
• Kugira ngo hirindwe ko amagufwa yagabanuka.
• Indwara yo kuvura indwara ya osteoporosis iterwa na glucocorticoid iterwa no gukoresha imiti imwe n'imwe ya steroid igihe kirekire.
• Kanseri zimwe na zimwe zitera urugero rwinshi rwa kalisiyumu mu maraso (hypercalcemia ifitanye isano na kanseri).
• Indwara ya Paget y'amagufwa ni indwara igira ingaruka ku magufwa.
• Indwara ya kanseri yitwa multiple myeloma.
• Ku bijyanye n'igihe kanseri yatangiriye ahandi yakwirakwiriye (yaranduye) ikagera no mu magufwa.

Hari igihe abaganga bakoresha uyu muti mu zindi ndwara zitari izo bemerewe. Urugero, hari igihe uhabwa abana n'abantu bakuru bafite ikibazo cy'uturemangingo cyitwa osteogenesis imperfecta .

Uyu muti ukora ute imbere mu mubiri?

Kugira ngo tubisobanukirwe, tugomba kubanza kumenya bike ku magufwa yacu. Amagufwa yacu ntabwo aba ahantu hamwe gusa. Ahora asimburwa. Nk'urukuta aho amatafari ashaje akurwaho hakubakwa andi mashya. Umubiri urasenyuka kandi ugakuraho amagufwa ashaje. Ibi tubyita resorption y'amagufwa. Hanyuma igufwa rishya riremwa muri ibyo bice.

Uko tugenda dusaza, cyane cyane ku bagore nyuma yo gucura, iyi gahunda iba idakora neza. Ni ukuvuga ko igufwa rishaje ritangira kwangirika no gukurwaho vuba kurusha uko igufwa rishya ribaho. Icyo gihe ni bwo amagufwa agenda arushaho kuba make kandi akagabanuka, bigatera indwara yo gucika intege kw'amagufwa.

Uyu muti nawukoresha nte? Ibi ni ingenzi cyane!

Uburyo bwo gukoresha buratandukanye bitewe n'ubwoko bw'umuti uhabwa.

Niba ibinini binyobwa mu kanwa...

Iki ni cyo gice ugomba kwitondera cyane . Muganga azakubwira gufata ibi binini rimwe ku munsi, rimwe mu cyumweru, cyangwa rimwe mu kwezi. Ariko, ugomba gufata ibi bininiHari uburyo bwihariye .

• Ugomba gufata iki ginini ukimara kubyuka mu gitondo, mbere yo kurya cyangwa kunywa ikindi kintu icyo ari cyo cyose .
• Ikinini kigomba gufatwa gusa n'ikirahure cyuzuye cy'amazi asanzwe . Birabujijwe cyane gufata iki kinini hamwe n'icyayi, ikawa, amata, cyangwa ibinyobwa by'imbuto.
• Nyuma yo gufata ikinini, ntugomba kuryama cyangwa ngo uryame nibura iminota 30 (wenda iminota 60). Ugomba kwicara cyangwa guhagarara ugororotse.
• Nanone, ntushobora gufata ikindi giryo, ikinyobwa, cyangwa imiti muri iki gihe cy'iminota 30-60.

Ni ngombwa gukurikiza aya mategeko neza. Bitabaye ibyo, umuti ushobora kudashyirwa neza mu mubiri kandi ushobora gutera aleriji mu muhogo no mu gifu. Muganga wawe azagusobanurira birambuye.

Niba ari inshinge zo guterwa mu mitsi...

Ubusanzwe uru rukingo rutangwa mu bitaro cyangwa mu ivuriro. Akenshi, uru rukingo rutangwa rimwe mu mwaka . Ariko, bitewe n'uburwayi, rushobora gutangwa kenshi.

Urashaka gukora ibindi bintu ukoresheje uyu muti?

Yego. Mu gihe ufata uyu muti, muganga wawe akunze kukugira inama zikurikira:

• Kurya ibiryo bikungahaye kuri kalisiyumu (urugero: amata, yawurute, foromaje, amafi mato, imboga z'icyatsi)
• Niba ufite ikibazo cyo kubura vitamine D, fata inyunganiramirire ya vitamine D.
• Niba udafite kalisiyumu ihagije mu byo kurya, fata ibinini bya kalisiyumu .

Nkwiye gufata uyu muti igihe kingana iki?

Ibi biterwa n'uko umeze n'uko umubiri wawe witabira imiti. Ubusanzwe, abaganga bagabanya igihe cyo kunywa ibinini kugeza ku myaka 5 , naho gutera inshinge za aside zoledronic mu mitsi kugeza ku myaka 3. Ibi ni ukugira ngo bakurinde ingaruka mbi zishobora kubaho iyo ukoresheje iyi miti igihe kirekire. Ariko, hari abantu bashobora gukenera kuvurwa igihe kirekire. Muganga wawe ni we muntu mwiza ugomba gufata icyemezo.

Reka kandi twige ku ngaruka mbi zishobora kubaho.

Kimwe n'indi miti yose, bisphosphonates ishobora gutera ingaruka mbi, ariko si buri wese uzibona.

Ese uyu muti koko ugira akamaro?

Yego rwose. Ubushakashatsi bwagaragaje ko iyi miti yongera ubucucike bw'amagufwa kandi ikagabanya cyane ibyago byo kuvunika.

• Alendronate: Igabanya kuvunika k'umugongo ku kigero cya 50%, naho imvune yo mu kibuno n'izindi mvune ku kigero cya 30%.
• Risedronate: Igabanya imvune y'umugongo n'izindi ndwara ku kigero cya 40%.
• Aside ya Zoledronic: Igabanya kuvunika k'umugongo ku kigero cya 70% naho imvune yo mu kibuno n'izindi mvune ku kigero cya 35%.

Ni ryari ngomba kubonana na muganga?

Niba ufata uyu muti, kora uko muganga akubwira.Ni ingenzi cyane kujya kwa muganga ku gihe. Ibi bizadufasha kureba niba umuti ukora kandi niba hari ingaruka mbi. Muganga wawe ashobora kandi kukugira inama yo gupima ubucucike bw'amagufwa yawe mu buryo bwa DXA.

Wibuke by'umwihariko:

Uyu muti ni umuti w'ingenzi cyane ushobora kunoza ubuzima bwawe no kukurinda ingorane zikomeye zishobora guterwa no kuvunika kw'igufwa. Niba ufite ikibazo cyangwa impungenge kuri ibi, menya neza ko ubiganiriyeho na muganga wawe mu buryo bweruye.