Unowanzo nzwa kuneta, kuneta, kana kudzikira uremu here? Paunoona chiremba, anogona kusarudza kuongorora mahormone ako. Kunyanya, hormone cortisol. Saka, bvunzo huru inoitirwa kutarisa kana mazinga e cortisol ako akajairwa iACTH Stimulation Test. Kunyangwe zita racho ringanzwika serakaoma, zviri nyore chaizvo. Ngatitaurei nezvazvo nhasi.
Zvichitaurwa zviri nyore, chii chinonzi ACTH Stimulation Test iyi?
Iyi bvunzo yekurapa. Kuti zvive pachena, inotarisa kuti nhengo dzako mbiri dzinonzi adrenal glands dzinopindura sei kune hormone inonzi ACTH (Adrenocorticotropic hormone) inobva muuropi hwedu. Izvi zvinonzwika zvichivhiringidza here? Zvakanaka, ngatizvifungei nenzira iyi.
Fungidzira kuti pituitary gland iri muuropi hwako yakafanana nemaneja wekambani hombe. Matumbu maviri madiki eadrenal ari pamusoro peitsvo dzako akafanana nevashandi vaviri vanoshanda mukambani iyoyo.
Kana maneja (pituitary gland) achida kuita chimwe chinhu, anotumira meseji inonzi 'ACTH' kuvashandi (adrenal glands). Kana meseji iyi yagamuchirwa, vashandi (adrenal glands) vanogadzira hormone inonzi 'cortisol' voiburitsa mumuviri. Iyi cortisol ihormone inokosha kwazvo mumuviri wedu. Inobatsira muzvinhu zvakawanda zvakaita sekudzora kushushikana, kudzora huwandu hweshuga muropa, uye kudzora BP.
Saka, zvinoitwa neACTH Stimulation Test ndezvekuti tinoisa hormone yeACTH yakagadzirwa nekunze (inonzi cosyntropin) mumuviri wako toona kana adrenal glands (vashandi) vako vachipindura nayo vogadzira cortisol nemazvo.
Bvunzo iyi inonyanya kushandiswa kuona chirwere chinonzi 'adrenal insufficiency' . Izvi zvinoreva kuti ma adrenal glands haasi kugadzira cortisol yakakwana. Izvi zvakakamurwa kuita mhando nhatu.
| Rudzi rwekusakwana kweadrenal | Zvichitaurwa zviri nyore, chii chinoitika? |
|---|---|
| Kusakwana kweAdrenal Yekutanga | Dambudziko riripo pano ndere 'mushandi'. Kureva, nemagland eadrenal.Pane kukuvara kwakati. Hazvina mhosva kuti maneja (pituitary) anotumira mameseji mangani (ACTH), mushandi (adrenal) haagone kushanda. Cortisol haigadzirwe. Muenzaniso wakanakisa weizvi chirwere cheAddison . |
| Kusakwana kweAdrenal yechipiri | Dambudziko riripo pano ndere 'maneja'. Kureva kuti, pituitary gland haisi kutumira mameseji akakwana (ACTH). Kunyangwe kana mushandi (adrenal) ari mutano, haasi kushanda nekuti hapana mashoko. Cortisol haigadzirwe. |
| Kusakwana kweAdrenal Yepamusoro | Dambudziko riri pano riri pa 'mukuru wepamusoro pe maneja'. Kureva kuti, nechikamu cheuropi chinonzi 'hypothalamus'. Ndipo panobva meseji ichienda kumukuru wepituitary kuti ishande. Kana meseji iyoyo ikasauya, maneja haazoshandi, saka mushandi haazoshandiwo. |
Chiremba anokuudza kuti uite bvunzo iyi mumamiriro api ezvinhu?
Panogona kunge paine zvikonzero zvakawanda nei chiremba wako angakurudzira bvunzo iyi.
- Kana bvunzo yeropa yapfuura yakaratidza mazinga e cortisol akaderera: Kana wakamboongororwa ropa nechimwe chikonzero chakaratidza mazinga e cortisol akaderera, unogona kukumbirwa kuti uite bvunzo iyi kuti uzvisimbise.
- Kana uine zviratidzo zvekusakwana kweadrenal cortex: Sezvatakambokurukura, kana uine zviratidzo zvakaita sekuneta nguva dzose, kudzikira uremu, kurwadziwa mudumbu, kuda kurutsa, dzungu, uye kuderera kweropa, bvunzo iyi inoitirwa kuona kana chirwere ichi chiri icho chinokonzera.
- Kana wave uchitora mishonga yemasteroid kwenguva yakareba: Kana ukashandisa mishonga yeglucocorticoid yakaita seprednisone kwenguva yakareba, pituitary glands yako neadrenal glands zvinogona kumira kushanda kwenguva pfupi. Saka, mushure mekunge warega kutora mushonga, bvunzo iyi inoitirwawo kuti ione kana glands dziri kushanda zvakanaka zvakare.
Unofanira kugadzirira sei bvunzo isati yaitwa?
Izvi zvakakosha zvikuru. Unofanira kutevedzera mirairo yachiremba wako nemazvo. Kazhinji, unogona kutaura zvinhu zvakaita seizvi.
- Kutsanya: Ungakumbirwa kuti usadye kana kunwa chero chinhu kwemaawa matanhatu usati waongororwa. Mvura chete ndiyo inobvumirwa.
- Zvirambidzo zvemitambo: Ungakumbirwa kuti usaite mabasa akadai sekurovedza muviri kwakaoma kwemaawa 12-24 bvunzo isati yaitwa.
- Chikafu: Dzimwe nguva ungakumbirwa kudya chikafu chine makabhohaidhiretsi akawanda.
- Kurega mishonga: Mimwe mishonga yaunotora (kunyanya ma steroids creams, mapiritsi, kana ma inhalers) inogona kukanganisa mhedzisiro yebvunzo. Saka, chiremba wako anogona kukukumbira kuti urege kuitora kwenguva pfupi. Usamborega kutora mishonga yako usati watanga wabvunza chiremba wako.
Mazinga e cortisol mumuviri wedu haana kufanana mukati mezuva. Anowanzova akanyanya mangwanani. Saka, bvunzo iyi inowanzoitwa mangwanani kudzivirira mhedzisiro yenhema.
Zvakanaka, ngationei zvichaitika pazuva rebvunzo.
Izvi hazvityise sezvaungafunga. Zvinowanzoitwa muchipatara kana kukiriniki yechiremba we endocrinologist. Hezvino zvinoitika nhanho nhanho.
1. Kutora ropa rekutanga: Kutanga, mukoti achatora ropa kubva mutsinga iri muruoko rwako. Izvi zvichatarisa huwandu hwe cortisol yako yekutanga bvunzo isati yatanga.
2. Kubaya jekiseni: Tevere, mukoti achakupa jekiseni rine ACTH yakagadzirwa (cosyntropin). Iyi inowanzoiswa mutsandanyama yeruoko rwako. Ichaita sesvosve diki riri kukuruma, asi richapera mushure memasekonzi mashoma.
3. Sampuro yeropa yechipiri neyechitatu: Uchatorwa imwe sampuro yeropa mushure memaminitsi makumi matatu mushure mekubaiwa jekiseni. Wobva watorwa imwe sampuro yeropa mushure memaminitsi makumi matanhatu . Izvi zvinoyera kuti adrenal glands yako yakagadzira cortisol yakawanda sei kubva pakubaiwa jekiseni.
4. Kutumira kurabhoritari: Samples dzeropa dzinotorwa dzinotumirwa kurabhoritari.
Paunotorwa ropa rako, unonzwa kakunzwa kakubaya kadiki. Izvozvo zvinopera mushure mechinguva. Unganzwa kakukuvadzwa kadiki pakatorwa ropa, izvo zvakajairika.
Mhedzisiro yacho ichawanikwa riini uye ichati chii?
Zvinogona kutora vhiki imwe chete kuti mhedzisiro yebvunzo iyi idzoke. Izvi zvinodaro nekuti kana mhedzisiro yagamuchirwa, chiremba wako achainyatsoongorora uye oienzanisa nezviratidzo zvako kuti asvike pamhedziso.
Chii chinonzi mhedzisiro yakajairika?
Mumunhu ane hutano hwakanaka, mushure mekubaiwa jekiseni reACTH, adrenal glands inofanira kukurudzirwa zvakanaka uye huwandu hwecortisol muropa hunofanira kuwedzera zvakanyanya. Chiremba wako achakutsanangurira kukosha kuri mumushumo wako werabhoritari uye huwandu hwakajairika.
Chii chinonzi Mhedzisiro Isina Kunaka?
Yeukai kuti chiremba wenyu ndiye munhu akakodzera kukutsanangurirai zvabuda muongororo yenyu. Saka musatya kufunga nezvezvabuda.
- Kusakwana Kweadrenal (kana paine dambudziko neadrenal glands): Mumunhu ane chirwere ichi, kunyangwe kana akabayiwa jekiseni reACTH, huwandu hwecortisol hahuwedzeri zvachose kana kuwedzera nechikamu chidiki. Izvi zvinodaro nekuti dambudziko riri muma adrenal glands, uye zvisinei nekuti anokurumidziswa zvakadii kubva kunze, haagone kugadzira cortisol.
- Kusakwana kweAdrenal Secondary (kana paine dambudziko nepituitary gland): Kana pituitary gland ikasaburitsa ACTH kwenguva yakareba, adrenal glands dzinodzikira zvishoma nezvishoma dzotanga kusashanda (atrophy). Kana munhu akadaro akabayiwa jekiseni reACTH, adrenal glands dzisingashande hadzigone kupindura nekukasika. Nokudaro, huwandu hwavo hwecortisol hunowedzera zvishoma kana kuti hahuwedzere zvachose.
Dzimwe nguva, kana dambudziko repituitary gland richangobva kuitika kana kuti rakangokanganiswa zvishoma, huwandu hwecortisol hunogona kukwira zvishoma. Chiremba wako ndiye munhu akakodzera kusarudza nezvese izvi.
Mharidzo Yekuenda Nayo Kumba
- ACTH Stimulation Test ibvunzo inotarisa kuti adrenal glands yako inopindura sei mashoko anobva kuuropi hwako.
- Izvi zvinonyanya kushandiswa pakuongorora chirwere chinonzi adrenal insufficiency.
- Tevedzera mirairo yachiremba nokungwarira usati waongororwa (zvakadai sekutsanya uye kurega kushandisa mishonga).
- Kuongororwa uku kunosanganisira kutora ropa, kubaya jekiseni, uye kutora mamwe masampuli eropa.
- Usazvidya mwoyo nezvemhedzisiro yacho. Chiremba wako achazvidudzira nemazvo uye achakuudza nezvematanho anotevera uye marapirwo, kana zvichidikanwa. Usatya kubvunza chiremba wako chero mibvunzo yaungave nayo.
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