Patinofunga nezveasthma, vazhinji vedu tinofunga nezveinhaler. Kutaura zvazviri, kune vanhu vazhinji, inhaler inobatsira zvikuru mukudzora asthma yavo. Asi dzimwe nguva, kunyanya kune avo vane asthma yakanyanya kuoma, pane dzimwe nguva apo zvinova zvakaoma kushandisa inhaler nemazvo. Kufema kunova kwakaoma uye kunonetesa. Saka nhasi tichataura nezvenzira itsva yekurapa yepamusoro yakatangwa kudzora mamiriro ezvinhu akadaro easthma. Inonzi Biologic Therapy.
Zvichitaurwa zviri nyore, chii chinonzi Biologic Therapy?
Uyu mushonga mutsva wekurapa asthma yakanyanya. Mushonga wekufema watinowanzo shandisa unozorodza tsandanyama dziri munzira dzekufema, zvichiita kuti zvive nyore kufema. Asi mushonga uyu wezvebhayoloji wakasiyana zvishoma.
Fungidzira kuti kune zvinhu zvidiki mukati memiviri yedu zvinokonzera asthma, ndiko kuti, kuzvimba mumhepo. Izvi zvinonzi ma antibodies, masero, kana mamorekuru . Kurapa kwebiologic kunonyanya kunanga uye kunodzivisa kushanda kwezvinhu zvinokonzera asthma. Zvakafanana nekutsvaga mudzi wedambudziko worigadzirisa.
Kurapa uku kunoderedza kuwanda kwechirwere cheasthma, kunovandudza hupenyu hwevanhu, uye kune vamwe vanhu, kunogona kutovandudza mashandiro emapapu kusvika pamwero wakati.
Mushonga uyu unopihwa sei mumuviri?
Kurapa kwemuviri hakugone kutorwa sepiritsi. Kunopihwa nenzira mbiri huru:
1. Sejekiseni: Iri ijekiseni pasi peganda. Mukurapa, rinonzi jekiseni repasi peganda .
2. Nekuiisa mutsinga: Kungofanana nekuisa munyu, mushonga unoiswa mumuviri kuburikidza ne cannula. Izvi zvinonzi intravenous (IV) infusion .
Chinhu chakakosha ndechekuti kurapwa ne biologic hakusi kwekurapa kwega. Kunofanira kushandiswa pamwe chete nemimwe mishonga yeasthma yauri kutotora.
Izvi zvinoreva kuti muchafanira kuramba muchitora mishonga yakanyorerwa nachiremba wenyu, yakaita se:
- Mishonga yeAllergy: Iyi inogona kusanganisira corticosteroids , antihistamines , uye mishonga yeAntileukotriene (yakadai seMontelukast ).
- Majekiseni eAllergy: Anonziwo immunotherapy , aya anogona kuderedza zviratidzo zveAllergy nekufamba kwenguva.
- Mushonga weAsthma: Chero mushonga weAsthma wakanyorerwa kudzora asthma yako yakanyanya unofanira kuenderera mberi nekurapwa uku.
Kurapa uku kwakakodzera ani chaizvo?
Kurapa kwemuviri hakupiwi kune vese varwere veasthma. Chiremba wako achafunga nezvezvinhu zvakati wandei asati akurudzire kurapwa uku. Ona kana wakambosangana nechimwe chezvinhu izvi.
- Kana zviratidzo zvako zvikasadzorwa kunyangwe uchishandisa mushonga wawakanyorerwa nachiremba weasthma, kunyanya mushonga wako wekufema, nemazvo .
- Kana uine zvimwe zvinhu zvakakwira muropa rako , kunyanya eosinophils ( rudzi rwemasero machena eropa anokonzera kuzvimba mumapapu) kana huwandu hwakawanda hwezvinhu zvinokonzera allergy (immunoglobulin E kana IgE) .
- Kana uchiziva chinokonzera asthma yako uye edza kuzvidzivisa, asi zviratidzo zvako zvichiripo .
- Kana ukamuka pakati pehusiku nekuda kwekunetseka kufema .
- Kana uchifanira kushandisa mushonga wako wekuponesa mweya kanopfuura kaviri pasvondo.
- Kana uchifanira kushandisa mishonga yakaita se corticosteroids kuderedza kuzvimba munzira dzemhepo kanopfuura kaviri pagore apo asthma yako iri kuwedzera.
- Kana uchifanira kuenda kuEmergency Department (ETU) kanopfuura kaviri pagore nekuda kwezviratidzo zveasthma.
- Kana waifanira kugara muchipatara uye kurapwa nekuda kweasthma.
Kana uine chirwere chakadai, zvakakosha kutaura nachiremba wako nezvekuti kurapwa kwebiologic kwakakunakira here.
Ndeapi marudzi emishonga yebhayoloji inoshandiswa pakurapa asthma?
Kune mhando dzakasiyana dzemishonga yemuzvarirwo inotenderwa nemasangano akaita seU.S. Food and Drug Administration (FDA). Imwe neimwe inoshanda nenzira yakasiyana zvishoma. Ngationei kuti chii.
| Zita remushonga (zita rechiratidzo) | Inoshanda sei uye yakakodzera ani? | Maitiro ekupa | Migumisiro yakajairika |
|---|---|---|---|
| Omalizumab (Xolair®) | Inorapa asthma inokonzerwa neallergies. Inovhara antibody inokonzera allergies. Yakakodzera vanhu vane allergies kuguruva, mhuka dzinovaraidza, mapete, chakuvhuvhu, nezvimwewo. | Jekiseni rimwe chete kana maviri mavhiki maviri kusvika mana ega ega. Pakutanga rinopihwa pasi pekutarisirwa nachiremba, uye mamwe anogona kuapihwa kumba. | Kurwadziwa kwetsandanyama, kurwadziwa kwemajoini, kuneta, kurwadziwa kana kuzvimba panzvimbo yekubaiwa jekiseni. |
| Mepolizumab (Nucala®) | Inorapa asthma inonzi eosinophilic. Inovhara chinhu chinonzi IL5 chinoshanda pa eosinophils muropa. | Jekiseni rimwe chete mavhiki mana ega ega. Rinogona kutorwa kumba. | Musoro, kurwadziwa kana kuzvimba panzvimbo yekubaiwa jekiseni, kurwadziwa kwemusana, kushaya simba, kuneta. |
| Reslizumab (Cinqair®) | Izvi zvinorapawo asthma ye eosinophilic. Kufanana nemepolizumab, inovhara (IL5). | Inopihwa semushonga wemutsinga mavhiki mana ega ega. Zvinotora isingasviki awa. Kutarisirwa nachiremba kunodiwa pakutanga. | Huro inorwadza, kurwadziwa kwetsandanyama. |
| Benralizumab (Fasenra®) | Inorapa asthma ye eosinophilic. Inoderedza huwandu hwe eosinophils muropa. | Madosi matatu ekutanga anopihwa mavhiki mana ega ega, uye mavhiki masere ega ega. | Musoro, pahuro panorwadza. |
| Dupilumab (Dupixent®) | Inorapa asthma inouraya eosinophilic. Inodzivisa zvimwe zvinhu zvinokonzera kuzvimba mumuviri. | Jekiseni rimwe chete mavhiki maviri ega ega. | Huro inorwadza, kurwadziwa kana kuzvimba panzvimbo yekubaiwa jekiseni, kuwedzera kwehuwandu hwemasero machena eropa. |
| Tezepelumab (Tezspire®) | Mushonga mutsva we asthma. Unorapa asthma yakanyanya nekuderedza kuzvimba. | Jekiseni rimwe chete mavhiki mana ega ega. | Huro inorwadza, musana unorwadza, majoini anorwadziwa. |
Mimwe mibvunzo yaungave nayo nezvekurapa uku
Zvakajairika kuti mibvunzo yakawanda iuye mupfungwa dzako paunenge uchikurukura nezvekurapa kutsva kwakadai. Ngatitarisei mhinduro dzacho.
Kurapwa kunotora nguva yakareba sei?
Kusvika pari zvino, hapana nhungamiro chaiyo yekuti mushonga uyu unofanira kutorwa kwenguva yakareba sei. Zvinogona kutora mwedzi mina kuti zvionekwe kana uri kurapa zviratidzo zveasthma. Saka, mushonga uyu unoonekwa semushonga wenguva refu.
Ndeipi mushonga webiologic wakanakisa?
Hazvigoneki kutaura kuti mushonga mumwe uri nani pane mumwe. Hapana tsvakurudzo iri kuitwa yekuenzanisa mishonga iyi nemumwe nemumwe. Chiremba wako ndiye achasarudza kuti mushonga upi wakakunakira. Achafunga nezvezvinhu zvakawanda, zvakaita sekuongororwa kwekufema kwako, kuongororwa kweropa, uye rudzi rweasthma yaunayo.
Ndinofanira kuramba ndichishandisa mushonga wekufema here?
Ehe! Zvechokwadi. Izvi zvakakosha zvikuru. Kunyangwe mushure mekutanga kurapwa ne biologic, usamborega kushandisa mushonga wako we inhaler nemimwe mishonga ye asthma. Kana asthma yako yave yakadzorwa zvakanaka, chiremba wako anogona kukwanisa kuderedza mushonga wako we inhaler nekufamba kwenguva. Asi sarudzo iyoyo iri kwauri.
Ndezvipi zvakanakira kurapwa kwe biologic?
Kubatsira kukuru kwekurapa uku ndekuderedza kuzvimba munzira dzekufema uye kudzora zviratidzo zveasthma. Pamusoro pezvo, kune zvimwe zvakanakira zvakawanda:
- Uchakwanisa kuita mabasa emuviri akajairika uye kurovedza muviri .
- Asthma inowedzera kuipa, nguva yekumhanya kuETU inoderera.
- Kudiwa kwemushonga weallergy kana kuti dose yawo kunogona kuderedzwa.
- Ndinorara zvakanaka nekuti handimuki husiku nekuti ndinonetseka kufema.
- Mazuva aunotadza kuenda kuchikoro kana kubasa nekuda kweasthma achaderera.
Pane njodzi here nekurapwa uku?
Kazhinji, kurapwa kwemuviri kwakachengeteka. Zvisinei, semishonga yese, kune dzimwe njodzi nemigumisiro.
- Kurwara kwakanyanya: Kashoma, vamwe vanhu vanogona kuva nekurwadzwa kwakanyanya nemushonga uyu. Unogona kukonzera mapundu paganda, kuvaviwa, mapundu, uye dzimwe nguva chirwere chinouraya chinonzi anaphylaxis . Asi usavhunduke. Ndosaka vanachiremba vachikutarisa kwemaawa maviri mushure mekukupa mushonga.
- Kuwedzera kwenjodzi yezvirwere zveparasitic: Mishonga ye biologic, kunyanya iyo inoderedza huwandu hwe eosinophils muropa, inogona kuwedzera njodzi yekuva nezvirwere zveparasitic. Ma eosinophils aya masero anobatsira masoja edu ekudzivirira muviri kurwisa zvipembenene, kunyanya helminths .
- Asthma inowedzera kana kurapwa kukamiswa: Kana ukarega kurapwa ne biologic kamwe kamwe, pane mukana wekuti zviratidzo zvako zveasthma zvichawedzera kuipa kupfuura kare.
Ndinguva ipi yaunofanira kutaura nachiremba wako?
Iva nechokwadi chekutaura nachiremba wako muzviitiko zvinotevera.
- Kana zviratidzo zveasthma yako zvikasavandudzika kana kuti zvichiratidza kunge zviri kuwedzera mushure memwedzi yakati wandei yekurapwa.
- Kana zviratidzo zvitsva zvekurwara nepfungwa (zvakaita semapundu eganda, kuvaviwa) zvikatanga kuoneka.
- Kana ukapotsa zuva iroro unofanira kutora mushonga wako kana kuti unofanira kuuchinja.
- Kana muine mimwe mibvunzo kana kusava nechokwadi nezvekurapa uku.
Ndingawana kupi kurapwa uku? Kunofukidzwa neinishuwarenzi here?
Chiremba ane hunyanzvi mukurapa asthma ndiye achasarudza kana kurapwa kwemuviri kwakakunakira. Iye achaongorora zviratidzo zvako, mishonga yauri kushandisa, uye zvabuda mukuongororwa kweropa. Kurapa uku kunowanzoitwa muhofisi yenyanzvi kana muchikamu chakakosha (infusion centre) kuchipatara.
Kurapwa uku kunogona kudhura zvakanyanya, saka taura nachiremba wako kuti uone kana inishuwarenzi yako ichizobhadhara. Iye anogona kukubatsira kuti uve nechokwadi nekutaura nekambani yako yeinishuwarenzi. Mamwe makambani emishonga anopawo mapurogiramu ekubatsira vanhu vanorapwa uku.
Mharidzo Yekuenda Nayo Kumba
- Kurapa ne biologic inzira yepamusoro yekurapa asthma yakaoma iyo yakaoma kudzora nemishonga yechinyakare.
- Izvi hazvimbofi zvakatsiva mushonga wako wekufemesa. Unofanira kuramba uchishandisa mushonga wako wekufemesa.
- Zvinogona kutora mwedzi yakati wandei kuti uone mhedzisiro yekurapwa, saka shivirira.
- Nyanzvi yako chete ndiyo inogona kusarudza kuti ndeipi mishonga yebhayoloji yakakunakira.
- Usati watanga kurapwa uku, iva nechokwadi chekukurukura nachiremba wako mabhenefiti nenjodzi dzinogona kuitika.
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