Unofanira kunge wakanzwa vanaamai vedu, vanababa, vanambuya, nasekuru vachiti, "Maiwe, muviri wangu wava kushata izvozvi," uye "Mapfupa angu aoma." Kutaura zvazviri, sezvatinokura, simba remuviri wedu rinoderera, uye simba remapfupa edu rinoderera zvishoma nezvishoma. Dzimwe nguva, kana chirwere ichi chakanyanya kuipa, kunyangwe kudonha kudiki kana kutobuda pamubhedha kunogona kutungamira panjodzi huru yekutyoka ruoko kana gumbo. Chirwere ichi umo mapfupa anova asina simba uye anooma chinonzi osteoporosis . Saka, nhasi tichataura nezvemhando yakakosha yemishonga inoshandiswa navanachiremba kudzora rudzi urwu rwekushaya simba kwemapfupa.
Zvichitaurwa zviri nyore, chii chinonzi ma bisphosphonates aya?
MaBisphosphonates imhando yemishonga inoshandiswa kurapa zvirwere zvakaita se osteoporosis inoderedza kuwanda kwemapfupa uye simba. Izvi zvinoreva kuti hapana mushonga mumwe chete une zita iri, asi musanganiswa wemishonga yakati wandei. Pamusoro pe osteoporosis, vanachiremba vanopawo mushonga uyu kune dzimwe nyaya dzine calcium yakawanda muropa (hypercalcemia).
Ngatitarisei mhando huru dzemishonga dziri muchikamu ichi. Iyi inouya mumhando mbiri huru. Imwe inonwiwa (mapiritsi anonwiwa nemuromo), uye imwe inopinzwa netsinga (IV) (mvura inoiswa mutsinga).
| Maitiro ekupa mushonga | Mienzaniso yemishonga (inowanzoshandiswa muSri Lanka) |
|---|---|
| MaBisphosphonates emuromo | Alendronate, Risedronate, Ibandronate |
| Mvura inopinzwa mutsinga (IV Bisphosphonates) | Zoledronic acid, Pamidronate |
Mushonga uyu unokanganisa sei muviri?
Kuti tinzwisise izvi, tinofanira kutanga tanzwisisa zvishoma nezve mashandiro anoita mapfupa edu. Funga nezvemapfupa edu sechivako chiri kugadziriswa nguva dzose. Miviri yedu inoputsika uye inobvisa mapfupa ekare, asina simba. Maitiro aya anonzi mapfupa anonyungudika.Panguva imwe chete, pfupa idzva rakasimba rinoumbwa munzvimbo dzarakabviswa. Chero bedzi maitiro maviri aya ari pakati nepakati, mapfupa edu anoramba akasimba.
Zvisinei, sezvatinokura, kunyanya mushure mekuguma kuenda kumwedzi kuvakadzi, kuenzana uku kunorasika. Chinoitika ndechekuti pfupa rekare rinoputsika nekukurumidza kupfuura pfupa idzva rinoumbwa. Mugumisiro wacho ndewokuti mapfupa anova matete zvishoma nezvishoma, anobuda maburi, uye anoshaya simba.
Saka, zvinoitwa nemabisphosphonates aya kudzora zvakanyanya uye kuderedza mwero wekusvetwa kwemapfupa. Zvadaro, nekuti pfupa rekare rakasimba panguva iyo pfupa idzva riri kuumbwa, huwandu hwemapfupa uye simba rawo rinowedzera. Zvichitaurwa zviri nyore, zvinomisa kurasikirwa kwemapfupa.
Mabisphosphonates anoshandiswa mumamiriro ezvinhu api?
Vanachiremba vanonyanya kukurudzira mushonga uyu kune zvinotevera:
- Osteoporosis chirwere chinoitika kuvakadzi mushure mekuguma kuenda kumwedzi.
- Osteoporosis muvarume.
- Kudzivirira kuitika kwe osteoporosis.
- Osteoporosis inokonzerwa nekushandisa mishonga yakaramba ichishandisa mishonga yakaita semasteroid (glucocorticoids).
- Chirwere chePaget chepfupa chirwere chinoita kuti mapfupa akure zvisina kujairika.
- Dzora matambudziko anoitika nemarudzi akasiyana ekenza (semuenzaniso Multiple Myeloma) uye kana masero ekenza akapararira kuenda kumapfupa (Bone Metastasis).
- Kudzora hypercalcemia inokonzerwa nekenza (kuwedzera kwecalcium muropa nekuda kwekenza).
Ndinofanira kushandisa mushonga uyu sei? Izvi zvakakosha zvikuru!
Zvakakosha kutevedzera mirairo iyi nemazvo kuti uwane rubatsiro rwakakwana rwemushonga uye kuderedza migumisiro yakaipa.
Mishonga yemuromo
Nzira yekunwa mapiritsi aya yakanyatsojeka. Unofanira kutevedzera mirairo yachiremba nemazvo.
- Piritsi rinofanira kutorwa mangwanani, usati wadya kana kunwa chero chinhu (usina chinhu mudumbu) .
- Piritsi rinofanira kunwiwa negirazi remvura chete (mvura isina kupfava) . Zvinorambidzwa zvachose kutora mushonga uyu nezvinhu zvakaita setii, kofi, mukaka, kana zvinwiwa zvemichero.
- Chinonyanya kukosha: Mushure mekutora mushonga, unofanira kugara kana kumira kwemaminitsi angangoita makumi matatu kusvika makumi matanhatu . Usakotama, kurara pasi, kana kurara chero chikonzero chipi zvacho.
- Chikonzero cheizvi ndechekuti mushonga uyu unogona kukuvadza gumbo. Njodzi iyoyo inobviswa kana wamira nekuti mushonga wacho unopinda nekukurumidza mudumbu.
- Hazvina kunaka kudya kana kunwa chimwe chinhu mukati menguva iyi yemaminitsi makumi matatu kusvika makumi matanhatu. Kana nguva iyoyo yapera, unogona kudya kudya kwemangwanani semazuva ese.
Mishonga yemuchina wechina
Haugone kuita izvi kumba. Kurapa uku kunoitirwa muchipatara kana kukiriniki. Zvichienderana nemamiriro ako ezvinhu, jekiseni iri (infusion) rinowanzoitwa kamwe chete pagore kana mwedzi mishoma yega yega.
Paunenge uchitora mushonga uyu, chiremba wako anowanzo kurudzira kuti udye chikafu chine calcium yakawanda (mukaka, yogati, chizi, hove diki) uye utore vhitamini D , sezvo zvese zvichikosha kuti mapfupa arambe akasimba.
Ndezvipi migumisiro yakaipa ye bisphosphonates?
Sezvinongoita mimwe mishonga, panogona kunge paine mimwe migumisiro. Asi musazvidya mwoyo, mizhinji yacho idiki.
| Rudzi rwemushonga | Migumisiro inogona kuitika |
|---|---|
| Mishonga yemuromo | Matambudziko emudumbu akadai sechirungurira, GERD, esophagitis, kurwadziwa mudumbu, uye maronda. (Izvi zvinogona kudzivirirwa zvakanyanya nekutevera nzira chaiyo yekutora mushonga wako.) |
| Mishonga inopinzwa netsinga (IV) | Zviratidzo zvakafanana nezvechikosoro kana furuu, zvakaita sefivha, kurwadziwa kwemuviri, musoro, uye kurwadziwa kwemajoini netsandanyama, zvinogona kuitika kwezuva rimwe kana maviri mushure mekutora mushonga. Izvi zvinowanzopera mukati memazuva mashoma. |
Migumisiro isingawanzoitiki asi yakakodzera kuzivikanwa
Kunyangwe izvi zvisingawanzoitiki , zvakakosha kuti uzvizive.
- Osteonecrosis yeshaya: Njodzi iyi idiki zvikuru, kunyanya mushure mekuvhiyiwa kwakadai sekubviswa kwezino. Saka kana uri kutora mushonga uyu, udza chiremba wemazino pese paunomuona.
- Kutyoka kwechiuno zvisina kujairika: Izvi hazviwanzoitiki pakati pevanhu vanotora mushonga uyu kwenguva yakareba (makore anopfuura 3-5).
- Matambudziko emaziso: Kuzvimba (uveitis, scleritis) kwezvikamu zvakasiyana zveziso kunogona kuitika.
Chinhu chinonyanya kukosha ndechekuti njodzi yekutyoka pfupa nekuda kwe osteoporosis kana ukasatora mushonga uyu yakakura zvakapetwa chiuru pane njodzi diki yemigumisiro iyi. Saka, zvakakosha kutevedzera mirairo yachiremba wako.
Unoda kunoona chiremba zvakare riini?
Kana uri kutora mushonga uyu, zvakakosha kuti unoona chiremba wako nguva nenguva kuti utarise kana mushonga wacho uchishanda uye kana paine zvimwe zvinokanganisa. Unogona zvakare kutumirwa kuna chiremba wemapfupa (Endocrinologist kana Rheumatologist).
Chiremba wako anogonawo kukurudzira kuti uedze DXA scan kuti uone kuti mapfupa ako akakora zvakadii.
Chiziviso Chakakosha: Kana wave uchishandisa mushonga uyu kwemakore anopfuura matatu uye uchinzwa kurwadziwa kutsva muhudyu mako kana muhudyu, usazviregeredza uye zivisa chiremba wako nekukasika.
Mharidzo Yekuenda Nayo Kumba
- MaBisphosphonates mushonga unoshanda zvikuru unobatsira kusimbisa mapfupa asina simba nekuda kwe osteoporosis.
- Mishonga iyi inoshanda nekudzora mwero wekurasikirwa kwemapfupa.
- Kana uchinwa mushonga wekunwa, zvakakosha kuti unwe usina chinhu mudumbu, nemvura chete, uye ugare wakamira kana kugara kwemaminitsi makumi matatu kusvika makumi matanhatu mushure mekunwa mushonga.
- Kunyangwe paine migumisiro midiki inogona kuitika, migumisiro yakakomba haiwanzoitiki. Mabhenefiti emushonga uyu anopfuura njodzi dzacho.
- Kana muine mibvunzo, zvinokunetsai, kana kusava nechokwadi nezvemushonga uyu, taurai nachiremba wenyu nezvazvo pachena. Musamborega kutora mushonga wenyu musina kupiwa mazano nachiremba.
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