Unewo kuora mwoyo kwakanyanya here, kana kuti sezvatinodaidza vanachiremba kuti, Major Depression Disorder (MDD)? Kunyangwe mushure mekushandisa mushonga mumwe chete kana miviri yawakanyorerwa nachiremba, hausati wanzwa kuvandudzika kana shanduko? "Ndoita sei izvozvi?" Ungave uchifunga nekushungurudzika kukuru. Zvakajairika kunzwa uri wega uye usina simba panguva yakaita seiyi. Asi usatya. Hausi wega. Sainzi painofambira mberi, tariro itsva dzinomukawo. Nhasi tiri kutaura nezvetariro itsva yakadaro.
Kutanga, ngatikuyeuchidzei zvishoma nezvemishonga inowanzo shandiswa pakurapa kuora mwoyo inonyorerwa varwere.
Kana watanga kurapwa kwekuora mwoyo, chiremba wako anogona kunge akatanga akupa mushonga unonzi 'traditional antidepressant'. Kune mhando dzakawanda dzemishonga iyi. Mishonga iyi inoshanda nekuenzanisa mashandiro emakemikari muuropi, anonzi neurotransmitters , ayo anokanganisa mafungiro edu nemanzwiro edu. Izvi zvinosanganisira serotonin , norepinephrine , uye dopamine .
Asi pane zvimwe zvinonetsa nemishonga iyi. Imwe ndeyekuti inotora nguva kuti itange kushanda. Unowanzo fanira kumirira kwemavhiki mana kusvika masere kuti uone mhedzisiro. Imwe ndeyekuti mishonga iyi haishande zvakafanana kune wese munhu. Ongororo dzinoratidza kuti vanhu vaviri pavanhu vatatu vanoishandisa havapore zvakakwana .
Kuti zvive nyore kuti unzwisise, ngatitarisei mimwe yemishonga inonyanya kushandiswa patafura yakaita seiyi.
| Kirasi yeMishonga | Mienzaniso Yakajairika |
|---|---|
| SSRIs (Selective Serotonin Reuptake Inhibitors) | Citalopram, Escitalopram, Fluoxetine, Paroxetine, Sertraline |
| SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors) | Duloxetine, Venlafaxine |
| Mishonga Isingawanzoitiki Yekuora Mwoyo | Bupropion, Mirtazapine, uye Trazodone |
Kana wakamboedza mumwe kana kupfuura wemishonga iyi asi usinganzwe zviri nani, usazvidya mwoyo. Haisi mhosva yako. Inguva dzakadai apo vanachiremba vanofunga nezvekurapa kutsva uye kwemhando yepamusoro.
Saka ndedzipi nzira itsva dzekurapa idzi dzeNMDA?
Zvichitaurwa zviri nyore, iyi inzira yakasiyana zvachose yekurapa kushungurudzika. Kusiyana nemishonga yekare, kurapwa uku kunonangana nemareceptor ari muuropi anonzi N-methyl-D-aspartate (NMDA) .
Funga nezvazvo nenzira iyi. Mumunhu ane kuora mwoyo kukuru, zvimwe zvikamu zvakakosha zveuropi zvinogona kunge zvisingashande zvakanyanya, sekunge 'zviri kurara' (zvisina kushanda zvakakwana). Zvinoitwa neNMDA treatments kudzora mashandiro eimwe neurotransmitter ine simba inonzi glutamate , uye kusimbisa kubatana pakati pemasero europi 'ari kurara' (neurons). Izvi zvinoreva kuti zvinokurumidza kukurumidza kutaurirana kwemashoko pakati pemasero europi.
Nyanzvi dzinotenda kuti kumukazve uku kwekubatana kwemasero europi ndiko kunokonzera kudzikira kunoshamisa kwezviratidzo zvekuora mwoyo.
Chinhu chikuru cheizvi kukurumidza. Kunyange zvazvo mishonga yechivanhu ichigona kutora mavhiki kuti ishande, mimwe mishonga yeNMDA inogona kutanga kupa zororo guru uye shanduko mumurwere mumaawa mashoma .
Ndeapi marapirwo anoshandiswa neNMDA? Pane njodzi here?
Ketamine mushonga unoshandiswa kurapa kushungurudzika kusingarapike nekurapwa nekutarisa maNMDA receptors.
Izvi zvinowanzopihwa murwere kuburikidza netsinga (inopinzwa mutsinga kana kuti mutsinga) ine saline . Asi pane chimwe chinhu chaunofanira kurangarira pano.
Iyi haisiriyo nzira yekutanga iyo chiremba angakurudzira yekurapa kuora mwoyo.
Izvi zvinongoshandiswa chete kune varwere vane kuora mwoyo kwakanyanya vakaedza dzimwe nzira dzese asi vasina kubudirira. Zvakare, kurapwa uku kunoitirwa muchipatara, pasi pekutarisirwa kwakasimba kwevanachiremba vane hunyanzvi nevashandi vakadzidziswa. Uyu hausi mushonga unogona kutengwa kupharmacy woendeswa kumba.
Sei uchiita izvozvo? Nekuti semishonga yese, pane zvimwe zvinogona kukonzera migumisiro yakaipa. Panguva yekurapwa, unogona kusangana nekuchinja kweBP, dzungu, kuda kurutsa, uye dzimwe nguva kusawirirana nezviri kuitika. Kutarisirwa nachiremba kwakakosha kuti ugadzirise zvese izvi.
Ndingaziva sei kana ndakakodzera kurapwa uku?
Uyu ndiwo mubvunzo unonyanya kukosha. Mhinduro yemubvunzo uyu inogona kusarudzwa nachiremba wako ari kukurapa chete. Kana uri munhu akakodzera kurapwa kwepamusoro-soro seNMDA therapy zvinoenderana nezvinhu zvakati wandei:
- Ndeapi marudzi emishonga yekudzora kushungurudzika yawakamboshandisa kare?
- Dzakashandiswa kwenguva yakareba sei, uye pachiyero chakakodzera?
- Muviri wako wakaita sei nazvo?
- Kuoma kwezviratidzo zvako zvekushungurudzika pari zvino.
- Hutano hwako hwese (zvimwe zvirwere, mimwe mishonga yauri kutora, nezvimwewo).
Saka, chinhu chakanakisa chaungaita ndechekutaura pachena nachiremba wako nezve zvese zviri mupfungwa dzako. Usatya kubvunza mibvunzo yakaita sekuti, "Chiremba, ndave nemwedzi yakawanda ndichitora mushonga uyu, asi handisati ndaona musiyano," kana kuti "Hapana imwe nzira yandingakunda nayo here?" Paunonyanya kutaura nezvemanzwiro ako nezvawakasangana nazvo, zvinova nyore kuti chiremba wako asarudze mushonga wakanakira iwe.
Mharidzo Yekuenda Nayo Kumba
- Dambudziko guru rekushungurudzika (MDD) chirwere chakakomba chinoda kurapwa. Mishonga inoderedza kushungurudzika (SSRIs, SNRIs) haishande zvakaenzana kune wese munhu.
- Kune avo vasingapindure mishonga yechivanhu, ikozvino kune mishonga yemazuva ano yakaita seKetamine, iyo inotarisa maNMDA receptors.
- Izvi zvinogona kukanganisa glutamate muuropi, zvichisimbisa kubatana pakati pemasero europi nekukurumidza, uye zvichipa kuporesa nekukurumidza.
- Aya marapirwo ehunyanzvi, uye anopiwa chete kuvarwere vakakundikana mamwe marapirwo, vachitarisirwa zvakanyanya nechiremba muchipatara.
- Kana usiri kuwana zororo kubva mukurapwa kwauri kuita, usarasa tariro uye taura nachiremba wako pachena nezvesarudzo dzese.
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