Wakambozvibvunza here kuti ruzivo rwunofamba sei muuropi hwedu? Zvakafanana neboka revatumwa vadiki vanoshanda pamwe chete kuti vaite basa rinoshamisa. Tinodaidza ava kuti neurotransmitters. Dzimwe nguva, nekuda kwemamwe mamiriro ehutano, kutaurirana uku kwemashoko kunogona kuvhiringa zvishoma. Ndipo panouya mimwe mishonga kutibatsira. Nhasi tichataura nezveimwe mhando yemishonga yakadaro , inonzi dopamine antagonists.
Zvichitaurwa zviri nyore, chii chinonzi dopamine antagonists?
Kuti tinzwisise izvi, tinofanira kutanga taziva kuti chii chinonzi dopamine. Dopamine chinhu chakakosha zvikuru muuropi hwedu. Chinobatsira kudzora zvinhu zvakawanda, kusanganisira pfungwa dzedu, manzwiro edu, uye mafambiro edu.
Zvino fungidzira kuti masero edu europi ane 'makiyi' madiki. Tinoadaidza kuti 'mareceptor'. Mutumwa dopamine akaita se'kiyi'. Kana kiyi iyi yapinda mukiyi iyoyo (receptor), sero iroro rinotanga 'kushanda', zvichireva kuti rinotanga kuita basa raro.
Zvakanaka, saka mushonga unonzi 'dopamine antagonist' unoita sei? Mushonga uyu wakaita se 'kiyi yenhema' yaunogona kuisa mukiyi iyoyo, asi haugone kuvhura kiyi. Kureva kuti, mushonga uyu unopinda mukiyi `(receptor)` iyo dopamine inoda kumira, uye `(inoivhara)`.
Kuti zvive nyore, fungidzira chigaro chiri papati chine kadhi rakanzi 'Reserved'. Hapana akagara ipapo, asi haugone kugara ipapo, handiti? Ndiwo mashandiro anoita mushonga uyu. Unochengetedza dopamine receptor isingashande, uchidzivirira dopamine chaiyo kuti isapinde uye itange kushanda.
Nekuti inodzora kushanda kwemamwe masero europi nenzira iyi, mushonga uyu unobatsira zvikuru mukudzivirira mamwe matambudziko epfungwa nezvimwe zviratidzo.
Mushonga uyu unoshandiswa pamamiriro ezvinhu api?
Mishonga inopesana nedopamine inogona kukamurwa kuita mapoka maviri makuru, asi pane dzimwe nguva apo mimwe mishonga inoshanda mumapoka ese ari maviri.
1. Mishonga yekurwisa psychotic: Mishonga inoshandiswa kurapa psychosis nezvimwe zvirwere zvine chekuita nayo.
2. Mishonga yekuderedza kusvotwa: Mishonga inopiwa kumisa kuda kurutsa nekurutsa.
Ngatitarisei zvirwere zvikuru zvinorapwa nemishonga iyi.
| Rudzi rwemishonga | Matambudziko anorapwa |
|---|---|
| Mishonga inorwisa pfungwa |
|
| Mishonga yekudzivirira kupfava |
|
Ndeapi marudzi emishonga ari mumapoka aya?
Kune mhando dzakawanda dzemishonga dzinowira muzvikamu izvi. Mishonga yekurapa chirwere chepfungwa inowanzo patsanurwa kuita "zvizvarwa" zviviri. Kureva kuti, mishonga yekare yakawanikwa pakutanga (chizvarwa chekutanga) uye mishonga mitsva yakawanikwa gare gare, isina migumisiro yakawanda (chizvarwa chechipiri).
Mishonga yechizvarwa chekutanga (Yakajairika)
Iyi mimwe yemishonga yekare. Mimwe yacho ndeiyi:
- 'Chlorpromazine'
- `Haloperidol (Haldol®)`
- 'Fluphenazine'
- `Perphenazine`
- 'Prochlorperazine'
Mishonga yechizvarwa chechipiri (Atypical)
Iyi mishonga mitsva.
- `Olanzapine (Zyprexa®)`
- `Risperidone (Risperdal®)`
- `Quetiapine (Seroquel®)`
- `Aripiprazole (Abilify®)`
- `Clozapine (Clozaril®)`
Mishonga yekudzivirira kusvotwa nekurutsa
Ungave wakaona mimwe yemishonga iyi yakanyorwa pamusoro apa pane runyorwa rwezvirwere zvepfungwa. Chikonzero ndechekuti inogona kuita zvese izvi.
- `Metoclopramide (Reglan®)`
- 'Prochlorperazine'
- `Olanzapine`
- 'Haloperidol'
- `Domperidone` (Mushonga uyu hauwanikwe zvakanyanya muSri Lanka, uye unogona kuwanikwa chete kana wapihwa mvumo yakakosha)
Zvakakosha: Iyi ingori mienzaniso mishoma. Chiremba wako anogona kunge asina kunyora mushonga uri pane iyi runyorwa. Usambofa wakashandisa mushonga wemumwe munhu, rega kuutora, kana kuchinja mwero wemushonga usina kurairwa nachiremba wako.
Ndezvipi zvakanakira mishonga iyi?
Mishonga inobatsira zvikuru inonzi Dopamine antagonists.
Kune chirwere chepfungwa:
Kune munhu ane chirwere chakadai se psychosis, mushonga uyu unogona kuponesa hupenyu . Unogona kuderedza njodzi yekuti vanhu vane zvirwere izvi vazvikuvadze kana kushungurudzwa nevamwe. Unogona kuvapa mukana wakakura wekurarama hupenyu hwakanaka, kushanda, uye kufara nemhuri dzavo.
Kune kuda kurutsa nekurutsa:
Kwatiri, kurutsa kungava dambudziko rinongopera mushure mechinguva. Asi funga nezvemurwere ane kenza. Kusvotwa nekurutsa kwavanoita panguva yekurapwa chemotherapy kwakanyanya zvekuti kunogona kutoisa hupenyu pangozi. Dzimwe nguva dzakadai, kana mimwe mishonga isingashande, mishonga iyi yedopamine inogona kuvapa zororo guru.
Pane migumisiro kana njodzi dziripo here?
Ehe, semamwe mishonga, mishonga iyi inogona kuva nemigumisiro. Asi havasi vese vanowana migumisiro iyi yese. Zvinoenderana nezvinhu zvakawanda, zvakaita semushonga waunotora, chiyero, uye mamiriro emuviri wako. Chinhu chakakosha ndechekuti usatye izvi uye utaure pachena nachiremba wako.
| Mhedzisiro inogona kuitika | Tsananguro iri nyore |
|---|---|
| Kunyaradza | Izvi zvinowanzoitika pakutanga kwekutora mushonga. Izvi zvinodzikira kana muviri wajaira mushonga wacho. |
| Matambudziko ekufamba | - Akathisia:Kusagadzikana kwekusakwanisa kugara panzvimbo imwe chete, kunzwa sekunge uchifanira kuramba uchifamba-famba. - Dystonia: kusimba kwetsandanyama kamwe kamwe, kugwinha (semuenzaniso, kugwinha mutsipa kudivi rimwe chete). - Tardive Dyskinesia: Kufamba-famba kwechiso, muromo, kana rurimi kusingadzoreki kunogona kuitika nekushandisa mushonga kwenguva refu. |
| Kuderera Kweropa Kwenhengo Yemuviri | Kunzwa dzungu kana kushamisika paunongoerekana wasimuka kubva pawakagara kana kurara pasi. Izvi zvinokonzerwa nekudzika kamwe kamwe kweBP. |
| Kuchinja kwemahormone | Kuwedzera kwehomoni inonzi prolactin kunogona kukonzera kuti vakadzi vamire kuenda kumwedzi uye kuti vabude mvura yakaita semukaka mumazamu avo pavanenge vasiri kuyamwisa. |
| Chirwere cheNeuroleptic Malignant | Ichi chirwere chisingawanzoitiki asi chinogona kuisa hupenyu pangozi. Kana zviratidzo zvakaita sefivha yakanyanya, kuomarara kwetsandanyama, uye kurasikirwa nepfungwa zvikaitika kamwe kamwe, unofanira kuenda kuchipatara nekukurumidza kuEmergency Treatment Unit (ETU). |
Chiremba wako achakuudza zvakawanda nezvemigumisiro iyi uye achakupa mazano ezvaungaita kuti uzvideredze.
Mimwe mibvunzo yaungave nayo
Ndinofanira kutora mushonga uyu kwenguva yakareba sei?
Zvinoenderana nechirwere chauri kurapwa. Mimwe mishonga, senge mishonga yekudzivirira kuda kurutsa, inotorwa chete kana ichidikanwa. Asi mishonga yezvirwere zvepfungwa ingangoda kutorwa kwemakore, kana kutoti kwehupenyu hwako hwese. Chiremba wako ndiye achasarudza kuti unofanira kuitora kwenguva yakareba sei.
Ndinogona here kushanda kana kutyaira ndichitora mushonga uyu?
Uyu mubvunzo unokosha zvikuru. Mimwe yemishonga iyi inogona kukonzera hope dzakanyanya kana kuneta . Saka, unofanira kubvunza chiremba wako kana zvakachengeteka kutyaira kana kushandisa michina paunenge uchitora mishonga iyi. Iye achakupa mazano akanakisisa.
Mishonga inodzivirira dopamine iboka rakakosha remishonga yakabatsira kuvandudza hupenyu hwemamiriyoni evanhu. Kunyangwe iine migumisiro yakaipa, kana ikashandiswa zvakanaka pasi pekutungamirirwa nachiremba, mabhenefiti ayo anodarika ayo.
Mharidzo Yekuenda Nayo Kumba
- Mishonga inonzi dopamine antagonists inovhara ma receptors ari muuropi anogamuchira mameseji edopamine.
- Izvi zvinonyanya kushandiswa kurapa zvirwere zvepfungwa zvakaita sepfungwa dzakaipa uye kuda kurutsa zvakanyanya.
- Kunyangwe iyi iri mishonga inoshanda zvikuru, inogona kukonzera migumisiro yakaipa yakadai sehope nematambudziko ekufamba-famba.
- Usambofa watanga, wamisa, kana kuchinja mushonga uyu usina kurairwa nachiremba wako.
- Kana ukasangana nekusagadzikana kusingawanzoitiki paunenge uchishandisa mushonga uyu, usatya kuudza chiremba wako.
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