Pamwe iwe, kana mumwe munhu waunoziva, makanyorerwa mushonga unonzi Rifampin nachiremba. Uyu hausi mushonga waunomedza chete, asi unowanzopihwa sejekiseni mumuviri kuburikidza netsinga. Unoshandiswa kunyanya kune hutachiona hwakakomba seTB. Saka, ngatitaurei nezvemushonga uyu zvakadzama, asi muchiSinhala chiri nyore chaunogona kunzwisisa?
Zvichitaurwa zviri nyore, chii chinonzi Rifampin?
Rifampin mushonga unorwisa mabhakitiriya une simba guru unoshandiswa kurapa hutachiona hunokonzerwa nemabhakitiriya . Chinhu chakakosha kurangarira ndechekuti mushonga uyu unorapa hutachiona hwemabhakitiriya chete.
Mushonga uyu hauna simba pazvirwere zvinokonzerwa nemavhairasi, zvakaita sedzihwa nefuruu. Saka, zvakanaka kusashandisa mushonga werudzi urwu usina kunyorerwa nachiremba.
Mushonga uyu unogona kushandiswawo kune zvimwe zvirwere. Kana muine mibvunzo nezvazvo, bvunzai chiremba wenyu.
Usati watanga mushonga, iva nechokwadi chekuudza chiremba wako zvinhu izvi:
Usati watanga kurapwa neRifampin, zvakakosha kuti chiremba wako azive zvizere nezvehutano hwako. Iva nechokwadi chekuudza chiremba wako kana uine chimwe chezvirwere zviri pazasi.
| Hutano kana tsika | Sei uchifanira kuzivisa chiremba? |
|---|---|
| Chirwere cheshuga | Rifampin inogona kuchinja huwandu hweshuga muropa. |
| Chirwere chechiropa | Nekuti mushonga uyu unogona kukanganisa chiropa, zvakakosha kuzivisa chiremba kana uine chero matambudziko ehutano auripo. |
| Hunhu hweHIV kana AIDS | Mushonga uyu unogona kukanganisana nemishonga inotorwa yeHIV. |
| Kunwa doro kakawanda | Doro neRifampin zvinogona kukanganisa chiropa, saka njodzi yacho inogona kuwedzera. |
| Kuva nepamuviri kana kutarisira mwana | Unofanira kukurukura nachiremba wako nezvemigumisiro yemushonga uyu panguva yekuzvitakura. |
| Kuyamwisa | Pane mukana wekuti mushonga uyu unogona kupfuudzwa kumwana kuburikidza nemukaka wemuzamu. |
| Kupfeka magirazi ekuonana | Rifampin inogona kushandura maburi, akadai semisodzi nedikita, kuva neruvara rutsvuku-orenji, uye inogona kusvibisa magirazi ekuonana akapfava zvachose. |
| Kurwara nemimwe mishonga, chikafu, kana zvimwe zvinhu | Kana uine allergies kuRifampin kana chimwe chinhu chipi zvacho, zvakakosha kuzivisa chiremba wako usati watanga kurapwa. |
Mushonga uyu unopihwa sei?
Mushonga uyu unowanzoiswa zvishoma nezvishoma mutsinga (infusion). Kazhinji, uyu unopihwa nenyanzvi yehutano (chiremba kana mukoti) muchipatara kana kiriniki.
Mune zvimwe zviitiko, ungangoda kuzvipa mushonga uyu kumba. Kana zvakadaro, uchadzidziswa kugadzirira uye kuupa nemazvo. Zvakakosha zvikuru kutora mushonga sezvakarairwa, panguva yakakodzera, zuva nezuva . Ramba uchitora mushonga kusvika chiremba wako akuudza kuti urege.
Kurasa tsono nemasirinji
Kana uri kushandisa mushonga uyu kumba, usamborasa tsono nemasirinji akamboshandiswa mumarara . Pane chirongo chezvishandiso zvekupinza chakagadzirirwa ivo. Kana usina, bvunza chiremba wako.
Kana mushonga wacho wakawedzerwa (Overdose)
Kana uchifunga kuti wakatora mushonga wakawandisa netsaona, enda kuchipatara chiri pedyo neEmergency Department (ETU) nekukasika . Kana kufonera National Poisons Information Centre kuColombo National Hospital kuti uwane mazano.
Ndeipi mimwe mishonga inogona kupindirana nemushonga uyu?
Rifampin mushonga unogona kushanda pamwe chete nemimwe mishonga yakawanda, saka zvakakosha kuudza chiremba wako nezvemishonga yese yauri kutora.
Yambiro Yakakosha: Mimwe yemishonga inotevera haifanirwe kutorwa neRifampin. Saka kana uri kushandisa chero ipi zvayo, taurira chiremba wako nekukasika. Semuenzaniso, mimwe mishonga inorwisa mavhairasi yeHIV kana Hepatitis, yakaita sePraziquantel neVoriconazole.
Tafura iri pazasi inoratidza mimwe mishonga inogona kupindirana neRifampin. Rondedzero iyi haina kukwana, asi ichakupa pfungwa.
| Rudzi rwemishonga | Mienzaniso |
|---|---|
| Mishonga yekurwadziwa | Acetaminophen, Morphine, Oxycodone |
| Mamwe maantibayotiki | Doxycycline , Clarithromycin, Ciprofloxacin |
| Mishonga Inodzivisa Kubuda Kweropa | Warfarin, Clopidogrel, Ticagrelor |
| Mishonga yechirwere cheshuga | Glipizide, Glyburide, Rosiglitazone |
| Mishonga yezvirwere zvemwoyo neBP | Simvastatin, nemimwe mishonga yakawanda. |
| Mahormone echikadzi nemapiritsi ekudzora pamuviri | Mishonga ine estrogen neprogestins. |
| Mishonga yekurapa chirwere chepfungwa | Mishonga yekuderedza kushungurudzika uye kuzvidya mwoyo. |
Saka, kana uchienda kunoona chiremba wako, uya nerunyorwa rwemishonga yese, mavhitamini, mishonga yemiti, uye zvekudya zvinovaka muviri zvaunotora . Iva nechokwadi chekuudza chiremba wako kana uchisvuta kana kunwa doro.
Zvinhu zvekungwarira paunenge uchitora mushonga
- Zviratidzo: Kana zviratidzo zvako zvikasavandudzika, kana zvikawedzera kuipa, udza chiremba wako.
- Manyoka: Kana uine manyoka, usatore mishonga inotengwa nechiremba. Kana manyoka akatora mazuva anopfuura maviri, kana kuti akakomba uye aine mvura yakawanda, fonera chiremba wako.
- Kurwara kwakanyanya paganda: Izvi zvakakosha zvikuru. Kurwa kwakanyanya paganda kunogona kuitika kunyangwe mavhiki mashoma mushure mekutanga mushonga uyu. Kana ukatanga mapundu matsvuku/pepuru paganda ane fivha, kurwadziwa kwemuviri, kana mapundu acho akatsvuka, kana kuti ukaita maronda mumuromo mako, tsvaga rubatsiro rwechiremba nekukasika .
- Kudzivirira pamuviri: Mapiritsi ekudzivirira pamuviri anogona kunge asingashande zvakanaka paunenge uchitora mushonga uyu. Saka, taura nachiremba wako nezvekushandisa imwe nzira yekudzivirira pamuviri (semuenzaniso, makondomu) kudzivirira pamuviri.
- Mavhitamini: Zvingave zvakakosha kuwana vhitamini B6 nevhitamini D yakakwana paunenge uchitora mushonga uyu. Taura nachiremba wako nezvechikafu nemavhitamini auri kutora.
Migumisiro inogona kuitika
Kufanana nemushonga upi zvawo, Rifampin inogona kukonzera migumisiro yakaipa. Mimwe yakakomba, mimwe yakajairika.
| Migumisiro yakakomba inoda kurapwa nekukurumidza | |
|---|---|
| Kusawirirana kwemuviri | Mapundu paganda, kuvaviwa, kuzvimba kwechiso, miromo, rurimi, kuoma kufema. |
| Zviratidzo zvekukuvara kwechiropa | Kurwadziwa mudumbu rekumusoro kurudyi, kurasikirwa nechido chekudya, kuda kurutsa, tsvina yakachenuruka, weti yero/brown yakasviba, maziso kana ganda richitsvuka. |
| Zviratidzo zvekubuda ropa | Tsvina ine ropa kana kuti yanonoka, kurutsa kunoratidzika kunge kofi yakakuyiwa, mavara matsvuku/pepuru paganda, uye mavanga asina kutsanangurwa. |
| Kubuda kweganda/kubuda kweganda | Kutsvuka kweganda, maronda, kukwenya kweganda (kunyangwe mukati memuromo). |
| Zvinhu zvisingawanzove zvakakomba, asi zvinofanira kutaurwa kuna chiremba kana zvikaramba zviripo | |
| Kuchinja kweruvara rwemvura yemuviri | Weti, ziya, mate, misodzi, nezvimwewo zvinogona kuchinja ruvara rutsvuku rweorenji. Izvi zvinotarisirwa uye hazvikuvadzi. |
| Matambudziko ekugaya chikafu | Kusvotwa, kurutsa, gasi, chirungurira , kurasikirwa nechido chekudya. |
| Zvimwe zvinhu | Musoro , dzungu, hope, kuneta. |
Mharidzo Yekuenda Nayo Kumba
- Rifampin mushonga une simba unorwisa utachiona unopiwa hutachiona hwebhakitiriya, kwete mavhairasi.
- Mimwe mishonga yese, mavitamini, uye zvirwere zvauri kutoraUdza chiremba nezvazvo.
- Taura nachiremba wako nezvekushandisa imwe nzira yekudzivirira pamuviri , sezvo kushanda kwemapiritsi ekudzivirira pamuviri kunogona kudzikira paunenge uchitora mushonga uyu.
- Kana ukasangana nemigumisiro yakaipa, yakadai semaronda eganda akanyanya, kutsvuka kwemaziso, kana kubuda ropa kusingawanzoitiki , tsvaga rubatsiro rwechiremba nekukasika.
- Zvakajairika kuti weti yako, ziya, uye misodzi zviite setsvuku-orenji kwete chinhu chekunetseka nacho.
- Pedzisa mushonga wese wawakarairwa nachiremba, pasina kupotsa mushonga mumwe chete .
👩🏽⚕️ Mibvunzo yekuwedzera (Mibvunzo Inowanzo bvunzwa)
💬 Rifampin IV / Rifadin inoshandiswa pai?
Uyu mushonga une simba guru! Unonyanya kushandiswa kuparadza zvachose utachiona/mabhakitiriya anouraya anonzi 'Tuberculosis' uye 'Meningitis' yakakomba. Kana murwere akanyanya kurwara zvekusagona kunwa mapiritsi (muICU), vanachiremba vanobaya mushonga uyu zvakananga mutsinga (IV).
💬 Jekiseni iri (Rifampin) rinouraya sei mabhakitiriya ane TB anouraya kana rikabayiwa netsinga?
Kana mabhakitiriya eTB apinda mumuviri wedu, anogadzira RNA kubva muDNA yawo uye anoparadzira chirwere ichi. Kana mushonga uyu wangopinda muropa, unovhara/kudzivisa zvachose kugadzirwa kweRNA yemabhakitiriya, iyo chete fekitari inogadzira RNA mumabhakitiriya (RNA polymerase enzyme). Sezvo isingakwanise kutumira mameseji matsva/RNA, mabhakitiriya haagone kubereka uye anofa mukati memaawa.
💬 Ndezvipi migumisiro ine njodzi zvikuru yemushonga uyu une simba (Rifampin)?
Njodzi huru ndeyekuti inogona kukonzera '100% kukuvara kwechiropa' (Severe Hepatotoxicity / Liver Damage)! Kana ganda/maziso ako akaita yero (Jaundice), enda kuchipatara nekukasika. Chimwe chinhu chinoshamisa uye chinotyisa ndechekuti kana izvi zvikapinda mumuviri wako, 'weti yako, misodzi, uye ziya' zvinoshanduka kuva ruvara rwakajeka rwe'Orange-Red'! (Ndicho chinhu chinowanzoonekwa pamushonga uyu). Chimwe chinhu ndechekuti unobvisa 100% yesimba remimwe mishonga yauri kutora (semuenzaniso mapiritsi ekudzivirira pamuviri).
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