Ingabe izinso zakho ziphilile? Ake sifunde ngokuhlolwa kwe-Urine Protein Creatinine Ratio (UPCR) ngendlela elula!

Sawubona! Wake wacabanga ukuthi kukhona ukuhlolwa komchamo okulula kakhulu okungakutshela ukuthi izinso zakho zisebenza kahle yini? Leso esinye sezivivinyo esizokhuluma ngaso namuhla , ukuhlolwa kwe-Urine Protein Creatinine Ratio (UPCR) . Kungasitshela izinto eziningi ezibalulekile mayelana nempilo yezinso zethu.

Kuyini lokhu kuhlolwa (kwe-UPCR)?

Kalula nje, lokhu kuhlolwa (i-UPCR) kuwukuhlolwa okwenziwa kusampula yomchamo wakho. Ngokuyinhloko kubheka ukuthi ingakanani iphrotheni ne -creatinine emchameni wakho. Manje cishe uyazibuza ukuthi iyini le-creatinine, akunjalo? I-Creatinine iwumkhiqizo ongcolile okhiqizwa lapho amangqamuzana ethu emisipha esebenzisa into ebizwa ngokuthi i-creatine (ikhemikhali yemvelo enikeza imisipha amandla). Kufana nodoti oqongeleleka emakhaya ethu.

Uma izinso zakho ziphilile futhi zisebenza kahle, zihlunga imfucuza efana ne-creatinine egazini lakho bese ziyisusa emzimbeni wakho emchameni wakho. Ngakho-ke lokhu kuhlolwa (i-UPCR) kunikeza udokotela wakho ulwazi oluningi olubalulekile mayelana nendlela izinso zakho ezisebenza ngayo. Imiphumela yalokhu kuhlolwa ingasiza ekuboneni izimo ezingalimaza izinso zakho futhi ibone ukuthi noma yikuphi ukwelashwa osuvele ukuthatha kusebenza kahle kangakanani.

Ukuhlolwa (kwe-UPCR) kwenziwa nini?

Manje ake sibone ukuthi odokotela batusa kuziphi izimo lokhu kuhlolwa (i-UPCR).

Lokhu kuhlolwa kuvame ukwenziwa ukuze kubonakale ukuthi izinga leprotheyini yomchamo wakho liphakeme yini kunokujwayelekile, okusho ukuthi ungase ube ne -proteinuria ( iprotheyini emchameni), okungaba uphawu olukhulu lwesifo sezinso.

Ngakho-ke, izimo ezingase zikubangele ukuthi wenze lokhu kuhlolwa (i-UPCR) yilezi:

• Ngesikhathi sokuhlolwa kwakho kwezokwelapha okuvamile kwaminyaka yonke, ungenza ukuhlolwa kokuhlolwa ukuze ubone ukuthi une-proteinuria.
• Ngesikhathi sokukhulelwa, uma uba nezimpawu zesimo esibizwa ngokuthi i-preeclampsia (isimo esibucayi esihambisana nomfutho wegazi ophezulu ngesikhathi sokukhulelwa).
• Uma unezimpawu zesifo sezinso (isibonelo, ukuvuvukala, ukwehla komchamo, ukukhathala), noma uma izinga lakho le-creatinine egazini, elaziwa nangokuthi i-serum creatinine, liphezulu ngendlela engavamile, lokhu kuhlolwa (i-UPCR) kusetshenziselwa ukuthola umonakalo wezinso noma ukubona ukuthi unesifo sezinso esivele sikhona/ isifo sezinso esingamahlalakhona (i-CKD) nokuthi ukwelashwa kwakho kusebenza kahle kangakanani.

Lolu vivinyo (lwe-UPCR) lusebenza kanjani?

Kulungile, manje ake sibheke kabanzi ukuthi lokhu kuhlolwa (kwe-UPCR) kunikeza kanjani ulwazi oluningi mayelana nezinso zethu.

Njengoba wazi, izinso zethu ziyisitho esibaluleke kakhulu nesibalulekile ohlelweni lomchamo. Umsebenzi oyinhloko wezinso ezinempilo ukuhlunga imfucuza kanye noketshezi olwengeziwe egazini lethu bese kukhishwa emzimbeni njengomchamo. Phakathi kwale mfucuza kukhona i-creatinine. Futhi, amaprotheni, ayizakhi ezibalulekile zomzimba wethu, nawo adlula ezihlungini ezithambile zezinso.

Kodwa-ke, isici esikhethekile sezinso eziphilile ukuthi ziphinde zimunce la maprotheni ahlungiwe abuyele egazini. Ngoba la maprotheni enza imisebenzi eminingi ebaluleke kakhulu, njengokulinganisela inani loketshezi egazini lethu, ukulwa nezifo, nokukhiqiza ama-hormone nama-enzyme.

Ngakho-ke, cabanga, uma kukhona ubuthakathaka noma umonakalo ezinso, kuba nzima ukuthi lawa maprotheni ahlungwe futhi amuncwe kahle abuyele egazini. Bese, esikhundleni sokumuncwa egazini, lawa maprotheni abalulekile akhishwa emchameni. Yilokho okulinganiswa yilolu vivinyo (i-UPCR).

Ukuhlolwa kwe-UPCR uhlobo lokuhlolwa kokusebenza kwezinso. Kulinganisa amazinga ephrotheni kanye ne-creatinine emchameni ukuze kutholakale ukuthi izinso zonakele noma zisengozini yokulimala. Ukuhlolwa kwe-UPCR kubhekwa njengokunembile kakhulu ngoba kulinganisa isilinganiso sezinto zombili kusampula yomchamo efanayo, kunciphisa imiphumela yokushintsha kokuhlushwa komchamo ngezikhathi ezahlukene zosuku.

Ungalungiselela kanjani ukuhlolwa (kwe-UPCR)?

Lena enye into enhle ngalolu vivinyo. Akudingeki ulungiselele lolu vivinyo (i-UPCR) kusenesikhathi. Uma uya kudokotela, bazokucela ukuthi unikeze umchamo ebhodleleni elihlanzekile. Ngokuvamile, isampula yokuqala yomchamo ekuseni iyona engcono kakhulu, njengoba igxile kakhulu. Kodwa-ke, kungenziwa ngesampula ethathwe nganoma yisiphi isikhathi sosuku.

Kodwa-ke, kwezinye izimo ezikhethekile, njengoba izinga leprotheyini emchameni lishintsha usuku lonke, odokotela ngezinye izikhathi balinganisa leli zinga leprotheyini emchameni oqoqwe esikhathini samahora angama-24 ukuze banciphise lowo mphumela. Kodwa-ke, ku-(UPCR), isampula eyodwa ivame ukwanele.

Kwenzekani ngemva kokuhlolwa (kwe-UPCR)?

Ngemva kokunikeza isampula yomchamo wakho, kunezindawo ezinemishini emincane engayihlola ehhovisi likadokotela. Noma, izothunyelwa elabhorethri ekhethekile, ebizwa ngokuthi "ilebhu". Ilabhorethri izolinganisa ngokunembile amazinga eprotheyini kanye ne-creatinine emchameni wakho.

Uma imiphumela isifikile, udokotela wakho uzokufonela ukuze axoxe ngayo futhi axoxe ngokuthi yini okufanele uyenze ngokulandelayo. Uma isampula ithunyelwa elabhorethri, kungathatha usuku noma ezimbili ukuthola imiphumela, noma kungathatha isonto. Lokhu kuncike emsebenzini welabhorethri.

Yiziphi izinzuzo zokuhlolwa (i-UPCR)?

Uma sikhuluma ngezinzuzo zalolu vivinyo (lwe-UPCR), into eyinhloko ukuthi "aluhlaseli" olungalimazi umzimba., ukuhlolwa okusheshayo, okungenabuhlungu, futhi okulula kakhulu. Ngomchamo omncane nje, udokotela wakho angathola izinkomba ezibalulekile mayelana nezifo kanye nezimo ezahlukene zempilo ezithinta ukusebenza kwezinso zakho. Kungasetshenziswa futhi ukuqapha ukusebenza kahle kokwelashwa kwezimo ezilimaza izinso zakho (isib. isifo sikashukela, umfutho wegazi ophakeme, kanye nokulimala kwezinso).

Ngokwesibonelo, cabangela ezinye izivivinyo zomchamo, njengokuhlolwa kwe-creatinine clearance . Lokhu kulinganisa amazinga e-creatinine kuphela (hhayi amazinga e-protein). Kulolu vivinyo, kufanele unikeze inani eliphelele lomchamo oqoqwe esikhathini esithile (ngokuvamile amahora angama-24). Yilapho ilabhorethri ingalinganisa khona umthamo womchamo okhiqizwe esikhathini esithile. Kunezinye izivivinyo, njengokuhlolwa kwe-protein yomchamo , okulinganisa kuphela i-protein emchameni wakho isikhathi eside, ngokuvamile amahora angama-24.

Kodwa-ke, njengoba lokhu kuhlolwa (i-UPCR) kulinganisa isilinganiso samazinga e-creatinine kanye namaprotheni, udinga ukunikeza isampula yomchamo eyodwa kuphela. Ngakho-ke, ngoba kugwema ukuphazamiseka kokuqoqa umchamo amahora angama-24, ukuhlolwa (i-UPCR) kuyindlela ethembekile elula esigulini futhi enikeza udokotela ulwazi olusheshayo .

Ingabe zikhona izingozi ngalolu vivinyo?

Lokhu kuyinto ongajabula ngayo. Azikho izingozi zempilo ezihlobene nalokhu kuhlolwa (i-UPCR). Lokhu kungenxa yokuthi akuyona into efakwa emzimbeni. Akuvamile kakhulu, uma isampula yomchamo ingaqoqwanga kahle noma ngesizathu esithile, imiphumela yokuhlolwa ingaba "engaphelele noma engacacile". Uma lokho kwenzeka, kuzodingeka unikeze esinye isampula yomchamo. Yilokho okubi kakhulu okungenzeka.

Kuthatha isikhathi esingakanani ukuthola imiphumela yokuhlolwa (kwe-UPCR)?

Imiphumela yalolu vivinyo ingase ibuyele kuwe ngokushesha njengoba ubungalindela, ngemizuzu embalwa (ikakhulukazi uma uhlolwa emtholampilo). Noma, uma uluthumela elabhorethri, kungathatha izinsuku ezimbalwa. Kodwa-ke, udokotela wakho uzokushayela ucingo ngokushesha nje lapho imiphumela isifikile futhi achaze ukuthi isho ukuthini.

Kusho ukuthini amazinga aphezulu amaprotheni emchameni?

Leli iqiniso elibaluleke kakhulu okudingeka sonke silazi. Uma izinso zakho ziphilile futhi zisebenza kahle, inani lamaprotheni akhishwa emchameni wakho ngosuku kufanele libe ngaphansi kwama-milligram angu-150. Inani (le-UPCR) ngokuvamile kufanele libe ngaphansi kuka-0.2 mg/mg (noma u-20 mg/mmol).

Kodwa-ke, ngezinye izikhathi amazinga amaprotheni emchameni angakhuphuka okwesikhashana. Izimbangela ezivamile zifaka:

• Ukuphelelwa amanzi emzimbeni (ukuntuleka kwamanzi emzimbeni ).
• Ukutheleleka , ikakhulukazi ukutheleleka komgudu womchamo.
• Ukukhulelwa (abanye besifazane abakhulelwe bangase babe ne-proteinuria encane, kodwa akuyona into embi njengase-preeclampsia).
• Ngemva nje kokuvivinya umzimba okunzima.
• Ukucindezeleka okukhulu kwengqondo noma ukucindezeleka ngokomzimba (isb. umkhuhlane).

Kodwa-ke, uma amazinga amaprotheni ephakeme kunokujwayelekile isikhathi eside, ngaphandle kwalezi zizathu zesikhashana, kungaba uphawu lokulimala okukhulu kwezinso noma ukuqhubekela phambili kancane kancane ekuhlulekeni kwezinso . Ngakho-ke, akuwona umqondo omuhle ukungazinaki lokhu.

Futhi, amazinga aphezulu amaprotheni emchameni angasiza udokotela wakho ukuthi abone futhi aphathe izimo ezifana nesifo sikashukela kanye nomfutho wegazi ophakeme , izifo ezimbili ezinkulu ezilimaza izinso.

Kufanele ngikhulume nini nodokotela wami mayelana nokuhlolwa (kwe-UPCR)?

Uma unemibuzo, ukungabaza, noma ubunzima bokuqonda imiphumela yokuhlolwa komchamo wakho (i-UPCR) , ungangabazi ukuxhumana nodokotela wakho . Udokotela wakho nguyena ozochaza imiphumela yakho futhi akunikeze iseluleko ngokuthi yiziphi izivivinyo okufanele uzenze ngokulandelayo, yiziphi izindlela zokwelapha okufanele uzithathe, nokuthi ngabe udinga ukwenza noma yiziphi izinguquko endleleni yokuphila.

Izinto ezibaluleke kakhulu okufanele uzikhumbule

Ngakho-ke, cishe usuyaqonda manje ukuthi ukuhlolwa kwe-Urine Protein Creatinine Ratio (UPCR) esikhulume ngakho kuwukuhlolwa okunikeza udokotela wakho ulwazi olubalulekile nolubalulekile mayelana nokuthi izinso zakho zisebenza kanjani. Kuyimpumuzo enkulu futhi ukuthi lokhu kuhlolwa komchamo kuyashesha, akubuhlungu, futhi akubangeli monakalo emzimbeni . Imiphumela yokuhlolwa (kwe-UPCR) ingasiza udokotela wakho ukuthi abone izimo ezingalimaza izinso zakho futhi zithinte impilo yakho iyonke, aqaphe izimo ezikhona, futhi alinganise impumelelo yokwelashwa.

Ngakho-ke, ungalokothi ukhohlwe ukukhuluma ngokukhululekile nangokwethembeka nodokotela wakho ngemiphumela yalolu vivinyo kanye nomthelela wazo empilweni yakho. Ukunakekelwa kwezinso zakho kusezandleni zakho!

Izinso , Ukuhlolwa Komchamo, i-UPCR, Amaprotheni, i-Creatinine, Isifo Sezinso, i-Proteinuria, Impilo, Umsebenzi Wezinso, Amaprotheni Omchamo