So obi wɔ w'abusua mu a ɔwɔ "Sickle Cell Disease"? Momma yɛnhwehwɛ mu yiye!

Ɛnnɛ yɛrebɛka tebea bi a ɛyɛ foforo kakra ma nnipa dodow no ara, nanso ebetumi abɛn mmusua binom yiye ho asɛm. Wɔfrɛ no Sickle Cell Disease (SCD). Ebia woate din yi pɛn. Nokwarem no, ɛyɛ yare a ɛne yɛn mogya wɔ abusuabɔ, kyerɛ sɛ, ɛne mogya no wɔ abusuabɔ, na efi awosu mu. Ma yɛnhwɛ nea ɛyɛ ankasa, nea enti a ɛba, ne nea wobetumi ayɛ bio wɔ ho.

Dɛn ne Sickle Cell Yare? Momma yɛnte ase kɛkɛ!

Sɛ yɛbɛka no tiawa a, sickle cell disease (SCD) yɛ yare a ɛka mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn nipadua mu, a awofo nya fi mmofra hɔ. Eyi yɛ mogya mu nyarewa a wonya fi awo mu a abu so wɔ wiase no mu biako. Afei hwɛ, protein bi a wɔfrɛ no hemoglobin wɔ yɛn mogya mu nkwammoaa kɔkɔɔ no mu . Saa hemoglobin yi ho hia paa. Efisɛ, ɛyɛ saa protein yi na ɛde oxygen kɔ yɛn nipadua nyinaa mu. Ɛte sɛ taksi a mframa pa wom. Mpɛn pii no, obi a ɔwɔ apɔwmuden mogya mu nkwammoaa kɔkɔɔ no yɛ kurukuruwa na ɛyɛ mmerɛw. Te sɛ rɔba bɔɔl nketewa. Esiane eyi nti, ɛnyɛ den sɛ wobetumi awea afa mogya ntini nketenkete a ɛwɔ nipadua no mu (yɛfrɛ no capillaries) mu na wɔama oxygen ama yɛn akwaa ne yɛn ntini nyinaa. Nanso, nea ɛto obi a ɔwɔ sickle cell yare ne sɛ nsakrae kakra ba saa hemoglobin yi mu. Wɔfrɛ saa hemoglobin a ɛnteɛ yi hemoglobin S. Eyi ma mogya mu nkwammoaa kɔkɔɔ no yɛ ɔsram a ɛyɛ ɔsram, anaa ɔsram fã, sen sɛ ɛbɛyɛ kurukuruwa na ɛyɛ mmerɛw. Ɛnyɛ ɛno nko, na mmom saa nkwammoaa yi yɛ den yiye, ɛnkotow ntɛm, na ɛbata ho. Wo de susuw ho hwɛ, dɛn na ɛba bere a saa nkwammoaa a ɛte sɛ nkankyee yi fa saa mogya ntini nketenkete no mu no? Wɔde wɔn ho hyɛ mu! Afei mogya no sɛe. Ɛno kyerɛ sɛ, yɛn akwaa ne yɛn ntini a ɛho hia sen biara no nnya mframa pa a ɛdɔɔso. Eyi nti na ɔhaw ahorow a emu yɛ den te sɛ ɛyaw a emu yɛ den, ɔyare mmoawa ahorow, akwaa a ɛsɛe, ne dwumadi a entumi nyɛ adwuma yiye betumi aba no. Ade foforo nso ne sɛ, saa nkwammoaa a ɛte sɛ sinkyi yi ntra ase nkyɛ te sɛ mogya mu nkwammoaa kɔkɔɔ a ɛteɛ no. Wowuwu ntɛmntɛm. Afei mogya mu nkwammoaa kɔkɔɔ ho yɛ na nipadua no bere nyinaa. Eyi ne nea yɛfrɛ no mogya a ɛtɔ kɔ nipadua mu . Sickle cell yare yɛ tebea a ɛkɔ so wɔ ne nkwa nna nyinaa mu. Nanso mma ɛnhaw wo, ayaresa ahorow wɔ hɔ a wɔde sa eyi. Sɛ wode saa ayaresa ahorow yi di dwuma a, wubetumi atew yare no ho sɛnkyerɛnne no so na woatrɛw wo nkwa nna mu.

So sickle cell yare ahorow wɔ hɔ?

Yiw, sickle cell yare ahorow pii wɔ hɔ. Awosu mu nkwaadɔm a obi nya fi n’awofo hɔ na ɛkyerɛ saa ahorow yi.

Hemoglobin SS (HbSS) a ɛma mogya tu .

Eyi ne sickle cell yare a emu yɛ den sen biara . Nnipa a wɔwɔ SCD no mu bɛyɛ 65% na wɔwɔ saa saa. Saa nkurɔfo yi nya hemoglobin S awosu mu abɔde no fi awofo baanu no nyinaa hɔ. Eyi kyerɛ sɛ wɔn hemoglobin dodow no ara anaa ne nyinaa nyɛ nea ɛfata. Eyi ma wonya mogya a ɛtɔ kɔ nipadua mu a enni sabea.

Hemoglobin SC (HbSC) a ɛma mogya tu .

Eyi yɛ nea emu nyɛ den anaasɛ ɛyɛ nea ɛkɔ fam.Type a ɛwɔ sorosoro. Nnipa a wɔwɔ SCD no mu bɛyɛ 25% na wɔwɔ eyi. Saa nkurɔfo yi nya hemoglobin S awosu mu abɔde no fi ɔwofo biako hɔ na wonya hemoglobin foforo a ɛnyɛ ne kwan so awosu mu abɔde a wɔfrɛ no hemoglobin C no fi ɔwofo foforo no hɔ.

Hemoglobin (HbS) Beta Thalassemia a ɛma mogya tu

Saa nkurɔfo yi nya hemoglobin S awosu mu abɔde bi fi ɔwofo biako hɔ na wonya awosu mu abɔde a ɛnteɛ a wɔfrɛ no beta thalassemia fi ɔwofo foforo no hɔ. Eyi nso yɛ nketewa abien:

• “Plus” (HbS beta +): Eyi yɛ ɔkwan a ɛka nnipa a wɔwɔ SCD bɛyɛ 8% na ɛtaa yɛ mmerɛw.
• “Zero” (HbS beta 0): Eyi yɛ ɔkwan a ɛka nnipa a wɔwɔ SCD bɛyɛ 2% na ebetumi ayɛ kɛse te sɛ hemoglobin SS (HbSS) yare no.

Ahorow afoforo a wɔntaa nhu

Nea ɛka eyi ho no, ahorow afoforo a wɔntaa nhu te sɛ hemoglobin SD (HbSD), hemoglobin SE (HbSE), ne hemoglobin SO (HbSO) . Saa nkurɔfo yi nya hemoglobin S awosu mu abɔde biako ne awosu mu abɔde foforo a ɛnteɛ a wɔfrɛ no D, E, anaa O.

Nsonsonoe bɛn na ɛda Sickle Cell Anemia ne Sickle Cell Yare ntam?

Ɛha na nnipa pii adwene tu fra. Sickle Cell Disease (SCD) yɛ asɛmfua a wɔde frɛ sickle cell yare ahorow a yɛaka ho asɛm wɔ atifi hɔ no nyinaa. Ɛte sɛ nkatanim. Ahorow a aka no nyinaa hyɛ saa nkatanim no ase. Nnuruyɛfo de asɛmfua "Sickle Cell Anemia" di dwuma ma SCD ahorow a emu yɛ den sen biara a ɛde mogya a ɛtɔ kɔ nipadua mu no nkutoo . Ɛne sɛ, ahorow a wɔfrɛ no hemoglobin SS (HbSS) ne hemoglobin beta zero thalassemia. Ate aseɛ?

Nsonsonoe bɛn na ɛda Sickle Cell Trait ne Yare ntam?

Nnipa binom wɔ sickle cell su no nkutoo . Eyi kyerɛ sɛ wonya hemoglobin S awosu mu abɔde no fi ɔwofo biako pɛ hɔ . Ɔwofo foforo no nya awosu mu abɔde a ahoɔden wom. Mpɛn pii no, nnipa a wɔwɔ sickle cell su no nkyerɛ sickle cell yare ho sɛnkyerɛnne. Nanso, wobetumi de saa awosu mu abɔde a ɛnteɛ yi akɔma wɔn mma. Eyi kyerɛ sɛ wɔyɛ awosu mu abɔde yi akurafo . Nanso ɛntaa nsi koraa sɛ nnipa a wɔwɔ sickle cell su mpo betumi anya akwahosan ho haw sɛ wɔn nsu ho tɔ wɔn kɛse anaasɛ wɔde wɔn ho hyɛ apɔw-mu-teɛteɛ a emu yɛ den mu a . Nhwehwɛmu da so ara kɔ so wɔ eyi ho.

Sickle cell yare abu so dɛn?

Nhwehwɛmufo bu akontaa sɛ nnipa bɛyɛ 100,000 wɔ United States nkutoo na wɔwɔ sickle cell yare. Ɛtaa ba nnipa a wofi Afrika mu. Wohu no nso wɔ Hispanic Amerikafo, ne nnipa a wofi Mediterranea, Mfinimfini Apuei, Indiafo, ne Asiafo abusua mu. Nnipa bi nso wɔ hɔ a wɔwɔ saa tebea yi wɔ Sri Lanka.

Dɛn na ɛde sickle cell yare ba?

Sickle cell yare no fi awosu mu nsakrae a ɛba awosu mu nkwaadɔm bi a wɔfrɛ no HBB awosu mu nkwaadɔm mu . Saa HBB awosu mu abɔde yi na ɛyɛ hemoglobin no fã biako. Nnipa a wɔwɔ SCD nya HBB awosu mu nkwaadɔm abien a wɔayɛ no foforo a ɛma hemoglobin a ɛnteɛ – biako fi ɔwofo biara hɔ. Wɔfrɛ eyi sɛ autosomal recessive agyapade. Eyi kyerɛ sɛ abofra a ɔwɔ SCD awofo baanu nyinaa kura awosu mu abɔde a wɔayɛ no foforo no biako (a ɛkyerɛ sɛ wobetumi anya sickle cell su no). Nanso, mpɛn pii no, saa awofo no nkyerɛ yare no ho sɛnkyerɛnne.

Hena na ɔwɔ asiane kɛse sɛ obenya sickle cell disease (SCD)?

Nnipa akuw binom taa nya saa yare yi. Wɔne:

• Nnipa a wofi Afrika (e.g. Amerikafo a wɔyɛ abibifo).
• Hispanic Amerikafo a wɔwɔ Amerika Kesee Fam ne Amerika Mfinimfini fam.
• Nnipa a wofi Mediterranea, Mfinimfini Apuei, India, ne Asia.

Dɛn ne sickle cell yare ho sɛnkyerɛnne?

Mpɛn pii no, sickle cell yare ho sɛnkyerɛnne fi ase da adi bere a abofra adi bɛyɛ asram 5 kosi 6 no. Saa sɛnkyerɛnne ahorow yi betumi ayɛ soronko wɔ onipa biara ho. Nnipa binom nya yare no ho sɛnkyerɛnne a emu nyɛ den, bere a afoforo nso betumi anya ɔhaw ahorow a emu yɛ den. Nsɛnkyerɛnne titiriw a wobetumi ahu ne:

• Ɛyaw a ɛtaa ba.
• Monemia : Eyi betumi ama obi abrɛ kɛse, ne ho ayɛ fitaa, na wayɛ mmerɛw.
• Jaundice : Wora a ɛyɛ kɔkɔɔ ne aniwa fitaa.
• Nsa ne anan a ɛho ahonhon a ɛyɛ yaw.

Dɛn ne nsɛnnennen a ɛwɔ tebea yi mu?

Sickle cell yare betumi aka nipadua no afã horow pii. Nsunsuanso ahorow bi fi ase mpofirim (ɛyɛ den), bere a afoforo nso kyɛ (ɛyɛ nea enni sabea). Saa nsɛnnennen yi betumi afi ase ntɛm na atra hɔ nkwa nna nyinaa.

Yeaw

Eyi ne ɔhaw a ɛtaa de sickle cell yare ba. Ɛyaw no ba bere a nkwammoaa a ɛte sɛ nkankyee no kɔhyɛ mogya ntini no mu na esiw mogya no kwan no. Ebia wobɛte ɛyaw a emu yɛ den mpofirim. Wɔsan frɛ eyi sɛ ɛyaw ho haw, sickle cell ahokyere, ntini a ɛsiw (VOC), anaa ntini a ɛsiw (VOE) . Saa ɛyaw ahorow yi betumi ayɛ nea emu nyɛ den anaasɛ emu yɛ den, na ebetumi afi ase mpofirim na akyɛ bere tenten biara. Ɛyaw no taa ba koko, akyi, nan, ne abasa mu. Ebia nnipa binom benya ɛyaw a enni sabea , a ɛkyerɛ ɛyaw a ɛtra hɔ kyɛ boro asram asia.

Mogya a ɛtɔ kɔ nipadua mu

Sickle cell yare de mogya a ɛtɔ kɔ nipadua mu ba efisɛ mogya mu nkwammoaa kɔkɔɔ wuwu ntɛmntɛm dodo. Mogya a ɛtɔ kɔ nipadua mu ne mogya mu nkwammoaa kɔkɔɔ a ɛte apɔw a ebetumi de mframa pa akɔ nipadua no nyinaa mu a enni hɔ. Eyi nti naƆbrɛ a ɛtra so, jaundice, ahomegye, adwenemhaw, ne ti a ɛyɛ hare betumi aba.

Chest Syndrome a Ɛyɛ Hu a Ɛyɛ Den

Eyi yɛ aduruyɛ mu tebea a egye ntɛmpɛ a ɛde nkwa to asiane mu . Ebetumi asɛe ahurututu no, ama ayɛ den sɛ ɔbɛhome, na ama mframa pa a ɛkɔ nipadua no afã afoforo no so atew. Saa ɔhaw yi ba bere a sickle cells siw mogya ne oxygen a ɛkɔ ahurututu no mu no kwan no.

Mogya a Ɛyɛ Nsuo

Sickle cell anemia ma asiane a ɛwɔ hɔ sɛ mogya bɛtɔ no yɛ kɛse. Eyi ma asiane a ɛwɔ hɔ sɛ mogya a ɛbɛtɔ wɔ ntini a emu dɔ mu (deep vein thrombosis - DVT) no yɛ kɛse. DVT nso betumi abubu na akɔhyɛ ahurututu mu (pulmonary embolism - PE).

Nnwodwoɔ

Sɛ sickle cells kɔhyɛ mogya ntini bi a ɛkɔ amemene no mu mu a, mogya a ɛkɔ amemene no mu no siw. Amemene no nnya mframa pa a ɛdɔɔso na ama ayɛ adwuma. Eyi betumi ama obi anya akisikuru . Nnipa a wɔwɔ SCD no mu bɛyɛ 10% benya ayaresa mu akisikuru. Nnipa a wɔwɔ sickle cell anemia no wɔ asiane kɛse mu sɛ wobenya ɔyare a ɛma obi hwe ase.

Anisoadehu mu Ɔhaw ahorow

Sickle cells tumi siw mogya ntini a ɛwɔ aniwa no mu. Eyi taa ba wɔ retina no mu . Ɛtɔ da bi a, yare no ho sɛnkyerɛnne biara nni hɔ na afei aniwa tumi ayera mpofirim, na ebetumi mpo ama obi ani afura daa.

Priapism a wɔde di dwuma

Priapism yɛ tebea a ɛma nkwammoaa a ɛte sɛ nkankyee a ɛwɔ ɔbarima akyi berɛmo mu no siw, na ɛma ɔsɔre a ɛkɔ so yɛ yaw ( priapism ). Ɛyaw akyi no, priapism betumi asɛe ade daa na ama ɔbarima no atumi ayɛ adwuma yiye . Priapism a ɛkyɛ bɛboro nnɔnhwerew anan no yɛ aduruyɛ mu asɛm a egye ntɛmpɛ.

Akwaa a ɛsɛe ne huammɔdi

Nnipa a wɔwɔ sickle cell yare no wɔ asiane mu sɛ wobenya ɔhaw ahorow wɔ wɔn koma, ahurututu, asaabo, ne akwaa afoforo ho efisɛ wonnya mogya ne mframa pa a ɛdɔɔso. SCD betumi ama akwaa pii adi nkogu .

So sickle cell su anaa yare ka nyinsɛn?

Mmea pii a wɔwɔ sickle cell yare no nyinsɛn a ahoɔden wom. Nanso asiane ahorow no dɔɔso. SCD betumi ama asiane a ɛwɔ hɔ sɛ obi benya mogya mmoroso, mogya a ɛbɛtɔ, nyinsɛn a ɛtɔ, nkokoaa a wɔn mu duru sua, ne awo a wɔawo wɔn ntɛm no ayɛ kɛse . Enti ɛho hia sɛ wudi wo duruyɛfo afotu akyi.

Ɔkwan bɛn so na wohu sɛ obi anya sickle cell yare?

Wɔ Sri Lanka, sɛnea ɛte wɔ aman pii mu wɔ wiase nyinaa no, wɔhwehwɛ akokoaa biara a wɔawo no foforo mu hwɛ sɛ ebia ɔwɔ sickle cell yare sɛ akokoaa a wɔawo no foforo nhwehwɛmu no fã . Nea ɛka eyi ho ne sɛ wobegye mogya ketewaa bi afi akokoaa no nan ase na wɔasɔ ahwɛ. Eyi nso hwɛ sɛ nyarewa afoforo dodow bi wɔ hɔ. Nea ɛbɛyɛ na abofra no duruyɛfo akyerɛ sɛ wɔahu yare no, ɔbɛyɛ hemoglobin electrophoresis nhwehwɛmu. Afei nso, wobetumi ahu sickle cell yare ansa na wɔawo akokoaa no denam nhwehwɛmu a wɔyɛ ansa na wɔawo no so . Saa sɔhwɛ ahorow yi bi ne:Eyinom bi ne chorionic villus nhwɛsode ne amniocentesis .

So aduru bi wɔ hɔ a edi mũ a wɔde sa sickle cell yare?

Yiw, nnompe mu ntini a wɔde si ananmu , a wɔsan frɛ no stem cell transplant no betumi asa sickle cell yare. Nea ɛka eyi ho ne sɛ wobegye nnompe mu ntini a ɛte apɔw afi obi a ɔwɔ apɔwmuden a ne awosu mu nkwaadɔm a ɛne ne ho hyia (te sɛ onua bi) hɔ na wɔde ahyɛ ɔyarefo no mu. Nanso, nnipa a wɔwɔ SCD no mu bɛyɛ 18% pɛ na wotumi nya nea ɛne no hyia a ɛte saa. Asiane ne nsɛnnennen nso wɔ nipadua foforo a wɔde ma yi mu. Wo duruyɛfo no ne wo bɛbɔ eyi ho nkɔmmɔ.

Dɛn ne ayaresa a wɔde sa sickle cell yare?

Nea ɛka sickle cell yare ho ayaresa ho ne nnuru, mogya a wɔde ma, nnompe mu ntini a wɔde si ananmu, ne awosu mu nkwaadɔm a wɔde sa yare . Ebia wobefi ase de nnuru a ekum ɔyare mmoawa adi ayaresa . Wɔma mmofra a wɔawo wɔn foforo a wɔwɔ SCD a emu yɛ den no nnuru a ekum ɔyare mmoawa mprenu da biara kosi mfe 5 de siw ɔyare mmoawa ano.

Nnuru afoforo

Nnipa pii a wɔwɔ SCD no de nnuru di dwuma de tew wɔn yare no mu den so na wɔsa yare no ho sɛnkyerɛnne. Eyinom bi ne:

• Voxelotor: Eyi betumi asiw mogya mu nkwammoaa kɔkɔɔ no kwan sɛ anyɛ te sɛ sinkyi na ɛnbata ho. Eyi betumi atew mogya mu nkwammoaa kɔkɔɔ bi a wɔsɛe no so, ama mogya a ɛkɔ akwaa ahorow no mu atu mpɔn, na ama mogya a ɛtɔ kɔ nipadua no mu no so atew.
• Crizanlizumab: Saa aduru yi boa ma mogya mu nkwammoaa kɔkɔɔ a ɛte sɛ sickle no ntumi nkɔbata mogya ntini no afasu ho . Eyi betumi ama mogya akɔ yiye na atew ɔfe ne ɛyaw so.
• Hydroxyurea : Eyi betumi atew SCD nsɛnnennen pii so anaasɛ asiw ano, te sɛ ɛyaw a ɛtaa ba, koko mu yare a emu yɛ den, ne mogya a ɛtɔ kɔ nipadua mu a emu yɛ den.
• L-glutamine: Eyi yɛ aduru a ɛma ɛyaw ano brɛ ase. Ebetumi aboa ma ɛyaw dodow a wowɔ no so atew. Nnuru afoforo a ɛma ɛyaw ano brɛ ase ne nnuru a ɛnyɛ steroid a ɛko tia ɔyare mmoawa (NSAID) ne opiate .

Mogya a wɔde ma

Ebia wo duruyɛfo bɛkamfo akyerɛ sɛ wɔmfa mogya bi mma na wɔde asa SCD nsɛnnennen na asiw ano.

• Mogya a wɔde ma a emu yɛ den:Eyinom boa ma wɔsa nsɛnnennen a ɛde mogya a ɛtɔ kɔ nipadua mu a emu yɛ den ba. Nnuruyɛfo nso betumi de adi dwuma wɔ ɔhaw ahorow te sɛ ɔyare a ɛma obi hwe ase, koko mu yare a emu yɛ den, ne akwaa a entumi nyɛ adwuma yiye ho.
• Mogya mu nkwammoaa kɔkɔɔ a wɔde ma: Eyinom betumi ama mogya mu nkwammoaa kɔkɔɔ a ɛwɔ nipadua no mu no ayɛ kɛse na ama wɔanya mogya mu nkwammoaa kɔkɔɔ a ɛteɛ a ɛnte sɛ sinkyi.

Stem cell transplant (a wɔsan frɛ no nnompe mu ntini a wɔde si ananmu) .

Wobetumi de ntini mu nkwammoaa a wɔde bɛma obi foforo asa SCD yare. Eyi hwehwɛ sɛ obi a ɔde mmoa ma a ɔfata yiye (te sɛ onua). Wɔreyɛ nhwehwɛmu nso de ama nipadua foforo a wɔde bɛma obi foforo afi awofo anaa anuanom a wɔn fã bi ayɛ pɛ no mu no ayɛ papa. Wo duruyɛfo begyina wo tebea pɔtee so asusuw asiane ne mfaso a ɛwɔ saa ayaresa yi so ho.

Awosu mu Awosu mu Ayaresa

Mprempren nhwehwɛmufo reyɛ nhwehwɛmu wɔ awosu mu ayaresa a wɔde sa SCD ho. Nea ɛka eyi ho ne sɛ wɔbɛteɛteɛ hemoglobin awosu mu abɔde a ɛnteɛ no anaasɛ wɔde hemoglobin awosu mu nkwaadɔm a ɛte apɔw bɛhyɛ obi ntini mu nkwammoaa mu. Eyi ho nsɛm a wodii kan nyae no yɛ nea ɛhyɛ bɔ kɛse. Anidaso no ne sɛ da bi awosu mu ayaresa bɛyɛ SCD ayaresa a wɔtaa yɛ.

So wobetumi asiw eyi ano?

Sickle cell yare yɛ awosu mu tebea, enti wontumi nsiw ano . Sɛ woanyinsɛn a, ɛbɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa afa awosu mu nhwehwɛmu anaa awosu mu afotu ho . Eyi bɛboa wo ne wo hokafo ma woahu sɛ ebia mowɔ awosu mu abɔde no ne asiane a ɛwɔ mu sɛ wode bɛma wo mma no.

Dɛn na obi a ɔwɔ sickle cell yare betumi ahwɛ kwan?

Ebia nnipa a wɔwɔ sickle cell yare no nkwa nna yɛ tiaa kakra sen nnipa dodow no ara. Nanso, ayaresa foforo a wɔde sa SCD no ama nkwa nna ne asetra pa atu mpɔn kɛse . Sɛ wɔhwɛ yare no so yiye a, nnipa a wɔwɔ sickle cell yare no betumi atra ase akodu wɔn mfe 50 mu.

Sɛ ɔwɔ sickle cell yare a, mɛyɛ dɛn ahwɛ me ba?

Sɛ wo ba wɔ sickle cell yare a, nneɛma pii wɔ hɔ a wubetumi ayɛ de adi ne tebea no ho dwuma:

• Fa wo ba no kɔ oduruyɛfo nkyɛn bere nyinaa.
• Ma wo ba no nnuru a wɔkamfo kyerɛ nyinaa wɔ bere ano.
• Boa wo ba ma ɔteɛteɛ n’apɔw mu daa na onni aduan a ɛma koma nya ahoɔden .
• Sɛ ɛyaw ho haw bi ba a, ma wo ba no nsu pii ne aduru a ɛnyɛ steroid a ɛko tia ɔyare mmoawa (NSAID) . Sɛ wuntumi nni ɛyaw no so wɔ fie a, fa wo ba no kɔ ayaresabea ma ɔnom nnuru a ano yɛ den a wɔde kum ɛyaw.

Bere bɛn na ɛsɛ sɛ wokɔ Emergency Treatment Unit (ETU) ?

Sickle cell yare betumi de ɔhaw ahorow a ɛde nkwa to asiane mu aba. Sɛ wo anaa wo ba nya sɛnkyerɛnne a edidi so yi mu biara a, frɛ 911 anaa kɔ baabi a ɛbɛn wo a wɔhwɛ wɔn a wɔwɔ yare a egye ntɛmpɛ (ER) ntɛm ara:

• Ɛyaw a emu yɛ den.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ mogya atɔ no kɛse: ɔbrɛ kɛse, adwenemhaw, ne ahome a ɛyɛ tiaa.
• Atiridiinini a ɛboro digrii Fahrenheit 101.3 (digrii Celsius 38.5).
• Anisoadehu mu haw ahorow.
• Ɔhome a ɛyɛ den.
• Penile erection a ɛkyɛ nnɔnhwerew anan anaa nea ɛboro saa (priapism).
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya koko mu yare a emu yɛ den: koko mu yaw, ɔfe, atiridiinini.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare a ɛma obi hwe ase: Ne nipadua no fã biako yɛ mmerɛw mpofirim, ne ho yɛ no yaw, anaasɛ n’adwene mu yɛ no naa.

Dɛn nti na sickle cell yare ma obi te yaw?

Sɛ yɛbɛka no tiawa a, mogya mu nkwammoaa kɔkɔɔ a ɛte sɛ nkankyee te sɛ nkyerɛwde C, anaa ɔsram a ɛyɛ ɔsram a ɛyɛ ɔsram a ɛyɛ ɔsram a ɛyɛ ɔsram no. Bere a wɔnam wo mogya ntini mu no, ɛkyere na esiw mogya no kwan. Ɛno na ɛyaw no ba. Fa no sɛ kar akwan a akyeakyea wɔ ɔkwan bi so.

So sickle cell yɛ yare a nipadua no tumi ko tia nyarewa?

Dabi Ɛwom sɛ sickle cell yare wɔ nyarewa a nipadua no tumi ko tia nyarewa no su ahorow bi de, nanso nnuruyɛfo mmu SCD sɛ ɛyɛ yare a nipadua no tumi ko tia nyarewa. Wobu SCD sɛ awosu mu tebea .

Sickle cell yare yɛ tebea a ɛkɔ so wɔ ne nkwa nna nyinaa mu. Ɛnyɛ bere nyinaa na wobetumi de ntini mu nkwammoaa a wɔde si ananmu, a ebetumi ama wɔasa no yare koraa, na asiane wom. Nanso, sɛ wohu yare no ntɛm na wɔsa yare a, ebetumi aboa ma yare no ho sɛnkyerɛnne so atew na atew asiane a ɛwɔ hɔ sɛ ɔhaw ahorow bɛba no so. Sɛ wonya ayaresa daa a, wubetumi atra ase a ɛyɛ nnam na ɛyɛ nnam.

Nea etwa to no, nneɛma bi a ɛho hia a ɛsɛ sɛ wokae (Take-Home Message) .

Okay, enti yɛaka sickle cell yare ho asɛm pii. Nneɛma atitiriw bi a ɛsɛ sɛ wokae ni:

• Sickle cell disease (SCD) yɛ mogya mu yare a wonya fi awo mu a mogya mu nkwammoaa kɔkɔɔ no nsusuwii sesa, na ɛde ɔhaw ahorow ba mogya a ɛkɔ so no mu.
• Nea enti titiriw a ɛte saa ne hemoglobin bi a ɛnteɛ a wɔfrɛ no hemoglobin S.
• Ɛyaw, mogya a ɛtɔ kɔ nipadua mu, ɔyare mmoawa, ne akwaa a ɛsɛe abu so.
• Sɛ́ wobehu no ntɛm na wɔasa no yiye no ho hia yiye. Wɔhwehwɛ nkokoaa a wɔawo wɔn foforo mu hwɛ sɛ ebia eyi te anaa.
• Ɛwom sɛ nnompe mu ntini a wɔde ma obi foforo betumi ayɛ aduru de, nanso ɛnyɛ nea ɛfata obiara. Ayaresa afoforo wɔ hɔ, te sɛ nnuru ne mogya a wɔde ma.
• Wubetumi ne yare yi atra ase yiye denam asetra mu nsakrae a wobɛyɛ, nnuruyɛfo afotu a ɛfata a wubedi akyi, ne ade a wobɛyɛ ntɛm wɔ tebea a egye ntɛmpɛ mu no so .

Sɛ wo anaa obi a wunim no wɔ nsɛmmisa bi fa sickle cell yare ho a, hwɛ hu sɛ wobɛkɔ oduruyɛfo nkyɛn akɔhwehwɛ afotu. Biribiara nni hɔ a ɛsɛ sɛ yesuro anaa yɛn ani wu. Nea ɛho hia sen biara ne sɛ wɔbɛbɔ wo amanneɛ! Sickle cell yare, hemoglobin, mogya mu nkwammoaa kɔkɔɔ, mogya a ɛtɔ kɔ nipadua mu, awosu mu nyarewa, ɛyaw ho haw, sickle cell ayaresa