Momma yensua hormone Leptin a ɛboa wo ma wohwɛ wo mu duru so no ho ade pii.

So woasusuw nea enti a ɔkɔm de yɛn, sɛnea yɛte nka sɛ yɛmemee bere a yɛadi aduan awie, ne nea enti a ɛnyɛ den mma ebinom sɛ wɔn mu duru bɛkɔ soro bere a ɛyɛ den ma afoforo sɛ wɔbɛtew wɔn mu duru so no ho pɛn? Ɛnnɛ yɛbɛka nnuru abɔfoɔ ketewa bi a wɔyɛ wɔ yɛn nipadua mu a ɛne yeinom nyinaa wɔ abusuabɔ ho asɛm. Wɔfrɛ no Leptin. Sɛ yɛbɛka no pɛpɛɛpɛ a, leptin yɛ hormone bi a yɛn srade nkwammoaa (adipose tissue) yi fi mu ba a ɛboa yɛn ma yɛkɔ so yɛ yɛn nipadua mu duru bere tenten.

Dɛn ne Leptin? Momma yɛnhwɛ no tiawa.

Fa no sɛ wo nipadua mu srade ma wonya hormone bi a wɔfrɛ no Leptin. Enti, Leptin adwuma titiriw ne sɛ ɛbɛhyɛ yɛn kɔm so na ama yɛanya atenka sɛ "ɛdɔɔso, mayɛ ma" (satiety) bere a yɛadi awie no. Ɛte sɛ ɔpanyin ketewaa bi a ɔhwɛ yɛn nipadua mu duru so.

Nyansahufo huu hormone leptin wɔ 1994. Ɛno kyerɛ sɛ pii da so ara wɔ hɔ a ɛsɛ sɛ wohu fa ho. Wɔreyɛ nhwehwɛmu dedaw sɛ ebia wobetumi de leptin adi dwuma de asa mu duru a wɔde siw ano, Alzheimer yare, awo akwahosan, ne awo a wontumi nwo anaa.

"Ah... sɛ leptin di mu duru so a, ɛnsɛ sɛ yɛn nso yetumi di leptin so?" ebia wubesusuw sɛ. Nanso, nokwasɛm ne sɛ, ɛnyɛ mmerɛw sɛ yebedi saa hormone yi so sɛnea yɛpɛ.

Dɛn na leptin yɛ ma yɛn nipadua?

Leptin adwuma titiriw ne sɛ ɛbɛboa ma yɛn nipadua mu duru akɔ so ayɛ nea ɛyɛ den. Nea ɛkɔ akyiri no, ɛboa ma yɛkari pɛ bere tenten wɔ aduan dodow a yedi ne ɔkwan a yɛn nipadua fa so de ahoɔden di dwuma no ntam. Ɛne sɛ, ɛboa ma yɛnte ɔkɔm nka bere a yɛn nipadua nhia ahoɔden (calories) no.

Leptin yɛ adwuma titiriw wɔ hypothalamus, yɛn amemene no fã bi a ɛhwɛ ɔkɔm ne yɛn ahoɔden a ɛkari pɛ so. Nanso, wohu nneɛma a ɛma wotumi te leptin nka nso wɔ yɛn nipadua no afã afoforo.

Nanso biribi a ɛsɛ sɛ yɛte ase ni. Leptin nyɛ hormone a ɛma ɔkɔm de yɛn bere a yɛadi aduan biako akyi. Mmom no, ɛboa yɛn ma yɛkɔ so tra yɛn mu duru so denam aduan dodow a yedi a ɛsakra bere kɔ so , a ɛhwɛ sɛnea yɛde ahoɔden di dwuma so, na ɛboa ma yɛhwɛ yɛn mu duru so.

Wote leptin nkɛntɛnso nka titiriw bere a worebɔ mmɔden sɛ wobɛtew wo mu duru so no. Susuw ho hwɛ, sɛ wo nipadua mu srade so tew a, wo leptin dodow nso so tew. Afei amemene no nya sɛnkyerɛnne bi a ɛka sɛ, "Oh, nipadua no nni aduan a ɛdɔɔso, ɛte sɛ nea yɛredi mmuada." Eyi nti na ɛtɔ mmere bi a ɔkɔm de wo kɛse na w’ani bere nnuan ahorow no. Afei wɔsɔ wo hwɛ sɛ wubedidi pii. Eyi betumi ama ayɛ den mpo sɛ wobɛtew wo mu duru so.

Nyansahufo da so ara reyɛ nhwehwɛmu wɔ Leptin ho. Wogye di sɛ Leptin nso ka yɛn:

• Nkwammoaa mu nneɛma a ɛsakra
• Endocrine nhyehyɛe - a ɛne sɛ, yɛn hormone nhyehyɛe
• Immune system - nhyehyɛe a ɛbɔ ho ban fi nyarewa ho

Ɔkwan bɛn so na wɔhwɛ leptin dodow so?

Leptin yɛ nea srade fitaa a ɛwɔ yɛn nipadua mu na ɛma ɛba. Saa srade fitaa yi ne srade titiriw a ɛwɔ yɛn nipadua mu. Sɛ yɛbɛka no tiawa a, ɛyɛ srade a ɛwɔ wo nipadua mu no.

Esiane sɛ srade nkwammoaa na ɛyɛ Leptin nti, Leptin dodow a ɛwɔ wo mogya mu no ne srade dodow a ɛwɔ wo nipadua mu no wɔ abusuabɔ tẽẽ. Ɛno kyerɛ sɛ, sɛ wo nipadua mu srade sua a, ɛnde na Leptin sua. Sɛ wowɔ nipadua mu srade pii a, ɛnde na wowɔ Leptin pii. Ɛyɛ mmerɛw, ɛnte saa?

Sɛ wo nipadua mu srade kɔ soro bere tenten a, wo leptin dodow bɛkɔ soro. Nea ɛne eyi bɔ abira no, sɛ wo nipadua mu srade so tew a, wo leptin dodow so bɛtew.

Sɛ leptin kɔ soro a, dɛn na ɛba?

Mpɛn pii no, leptin dodow kɔ soro wɔ nnipa a wɔayɛ kɛse mmoroso mu. Wɔfrɛ eyi hyperleptinemia. Sɛ leptin dodow kɔ soro bere nyinaa a, ebia yɛn amemene no rentumi nyɛ leptin ho biribi yiye. Wɔfrɛ eyi leptin a wɔko tia .

Tebea afoforo pii wɔ hɔ a ebia ɛne hyperleptinemia wɔ abusuabɔ:

• Hahaahayɔ
• Aduan a ɛma obi yɛ ade tra so
• Ntini mu yare a ɛma nipadua no yɛ adwuma yiye
• mmerɛbo mu yare a srade wom a ɛnyɛ nsa
• Rabson-Mendenhall syndrome - Eyi yɛ awosu mu tebea a ɛntaa nsi koraa.

Dɛn ne Leptin a Ɛko Tia?

Sɛ wowɔ Leptin Resistance a, w’amemene no ntumi nyɛ Leptin ho biribi sɛnea ɛsɛ. Fa no sɛ, Leptin kɔ so de nsɛnkyerɛnne kɔ amemene no so sɛ "Madi aduan a ɛdɔɔso, mayɛ me ma," nanso ɛte sɛ nea amemene no mfa ho. Enti, wonte nka sɛ wo ho ayɛ wo ma. Esiane eyi nti, wokɔ so didi, ɛwom mpo sɛ wowɔ srade pii a wode asie wo nipadua mu de.

Ɛnyɛ ɛno nko, na mmom esiane sɛ Leptin ntumi nyɛ adwuma yiye nti, amemene no susuw sɛ ɔkɔm de nipadua no na ɔkɔm de no. Afei, sɛnea ɛbɛyɛ na amemene no akora ahoɔden so no, ɛtew yɛn ahoɔden so, na ɛtew calories dodow a yɛde di dwuma bere a yɛregye yɛn ahome no nso so. Sɛ yɛbɛka no tiawa a, yɛn Basal Metabolic Rate (BMR) no so tew.

Enti wuhu sɛ leptin a ɛko tia no ma ɔkɔm de wo bere nyinaa, na ɛma wo BMR nso brɛ ase. Sɛ nneɛma abien yi bom a, mu duru a ɛkɔ soro no mu yɛ den kɛse mpo.

Mprempren nyansahufo reyɛ nnuru a ebetumi asa leptin a ɛko tia no ho nhwehwɛmu.

Dɛn ne Leptin Resistance ho sɛnkyerɛnne ahorow?

Leptin a ɛko tia ho sɛnkyerɛnne atitiriw ne ɔkɔm a ɛboro so a wɔte nka bere nyinaa (hyperphagia) ne adidi boro so. Saa sɛnkyerɛnne ahorow yi ba bere mpo a srade pii akora so wɔ nipadua no mu no.

Nanso, nneɛma ne tebea afoforo wɔ hɔ a ebetumi de saa sɛnkyerɛnne ahorow yi aba. Ɛnyɛ leptin a ɛko tia no nkutoo. Bere a nyansahufo da so ara resua leptin ho ade no, ebetumi aba sɛ wobehu leptin ho sɛnkyerɛnne pii daakye.

Sɛ leptin so tew a, dɛn na ɛba?

Leptin a enni nipadua no mu yɛ tebea a ɛntaa nsi koraa. Yare titiriw a ɛbata ho ne leptin a wonnya fi awo mu. Eyi yɛ awosu mu tebea a ɛwɔ hɔ bere a wɔawo no. Nnipa a wɔwɔ saa tebea yi no nnya leptin mfi wɔn srade ntini mu.

Sɛ leptin nni hɔ a, nipadua no susuw sɛ srade biara nni nipadua no mu. Eyi ma ɔkɔm ne adidi ho akɔnnɔ a wontumi nni so, ɛboro so. Esiane eyi nti, mmofra a wɔwoo wɔn a wonni leptin no nya kɛseyɛ mmoroso kɛse (kɛse mmoroso a ɛto so III) wɔ wɔn mmofraase pɛɛ, na wɔtwentwɛn wɔn mmabunbere ase.

Nyarewa afoforo a ebia ɛne tebea yi wɔ abusuabɔ:

• Dyslipidemia - srade a enni kari pɛ te sɛ cholesterol ne triglycerides
• Mmerɛbo mu yare a srade wom
• Mmoawa a wɔtaa de nyarewa ba
• Hyperinsulinemia - a ekyere se wobeye insulin dodoo
• Hypogonadotropic hypogonadism - kyerɛ sɛ, ɔbarima ne ɔbea nna mu hormone dodow a ɛba fam

Sɔhwɛ bɛn na wɔyɛ de hwɛ sɛnea leptin dodow te?

Wobetumi de mogya mu nhwehwɛmu asusuw leptin dodow. Nanso, nnuruyɛfo ntaa nsɔ obiara leptin dodow nhwɛ. Wɔkamfo kyerɛ sɛ wɔnyɛ leptin nhwehwɛmu wɔ nsɛm a edidi so yi mu:

• Sɛ wo ba kumaa wɔ kɛseyɛ mmoroso a ɛto so III a .
• Sɛ woyɛ kɛse mmoroso na ɔkɔm de wo bere nyinaa a .

Ɛsɛ sɛ leptin dodow a ɛfata yɛ dɛn?

Mpɛn pii no, leptin dodow betumi afi:

• Wɔ mmea fam no: Nanogram 0.5 kosi 15.2 wɔ mililita biara mu (ng/mL) .
• Wɔ mmarima fam no: Nanogram 0.5 kosi 12.5 wɔ mililita biara mu (ng/mL) .

Nanso kae sɛ saa mmeae a ɛfata yi betumi ayɛ soronko kakra wɔ aduruyɛdan ahorow mu. Enti, ɛyɛ papa sɛ wobɛhwɛ sɛnea ɛyɛ daa wɔ w’amanneɛbɔ no so. Anaasɛ, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo no ho asɛm.

Mɛyɛ dɛn atumi ama me leptin dodow akɔ soro?

Sɛ yɛbɛka nokware a, kakraa bi pɛ na yebetumi ayɛ de ama yɛn leptin dodow akɔ soro na ama ɔkɔm ne aduan ho akɔnnɔ so atew. Efisɛ sɛnea yɛadi kan aka no, wo leptin dodow ne srade dodow a wowɔ wɔ wo nipadua mu no wɔ abusuabɔ tẽẽ.

Nhwehwɛmu bi daa no adi sɛ nnipa a wɔnna pii no wɔ ɔkɔm hormone ghrelin dodow a ɛdɔɔso na hormone leptin nso sua. Enti, nna pa a wubenya no betumi aboa ma wo hormone ahorow no ayɛ adwuma yiye.

Nyansahufo nso reyɛ abusuabɔ a ɛda leptin ne srade bi a wɔfrɛ no triglycerides ntam no mu nhwehwɛmu. Nhwehwɛmu bi ada no adi sɛ triglyceride dodow a ɛkɔ soro no nya ɔkwan a leptin fa so yɛ adwuma no so nkɛntɛnso. Nanso adwene ahorow da so ara wɔ eyi ho. Nyansahufo binom susuw sɛ adidi nhyehyɛe a ɛtew triglycerides so no betumi aboa ma leptin dodow atu mpɔn. Nanso afoforo ne wɔn adwene nhyia.

Nnuan bɛn na Leptin dɔɔso wom?

Ɛha na nnipa pii di mfomso. Leptin yɛ hormone a wɔyɛ wɔ yɛn nipadua mu, ɛnyɛ aduannuru a yebetumi anya afi aduan te sɛ vitamin C anaa protein mu. Enti, biribiara nni hɔ a wɔfrɛ no nnuan a leptin wom.

Nea etwa to no, nneɛma a ɛho hia paa a ɛsɛ sɛ yɛkae no bi

Leptin yɛ ade foforo koraa a wɔahu ankasa, enti nyansahufo da so ara resua ho ade pii, titiriw sɛnea ɛka kɛseyɛ mmoroso ne mu duru a ɛso tew. Sɛnea wubetumi ahu no, bere a wo nipadua mu srade so tew no, leptin dodow so tew, na ɛkyerɛ sɛ wo nipadua no "redi mmuada," na ɛma ɛyɛ den sɛ wobɛtew wo mu duru so.

Sɛ wo mu duru ho asɛm haw wo anaasɛ wuhia akwankyerɛ wɔ sɛnea wobɛtew wo mu duru so yiye ho a, ɛbɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa. Wubetumi nso ne endocrinologist akasa afa nhyehyɛe ahorow a wɔde siw wo mu duru so ho.

Kae sɛ eyinom nyinaa yɛ nea ɛbɛboa wo ma woanya apɔwmuden. Ɛho hia sɛ wohwɛ wo nipadua no yiye.

` Leptin, mu duru a wɔde siw ano, hormone, ɔkɔm, kɛseyɛ mmoroso, srade, nipadua mu nneɛma a ɛsakra