Koma mu haw? Momma yensua BNP (B-type Natriuretic Peptide) sɔhwɛ no ho ade.

So woate BNP sɔhwɛ ho asɛm pɛn? Ebia wo duruyɛfo aka akyerɛ wo sɛ yɛ, anaasɛ woahwɛ mu bere a wowɔ komayare no. Ɛnnɛ, yɛbɛka nea BNP mogya mu nhwehwɛmu yi yɛ, nea ebetumi aka akyerɛ wo, bere a wɔayɛ, ne sɛnea wɔbɛkyerɛ nea efi mu ba no ase ho asɛm.

Dɛn ne BNP sɔhwɛ yi?

Sɛ yɛbɛka no tiawa a, saa BNP nhwehwɛmu yi kyerɛ sɛnea hormone titiriw bi a ɛwɔ wo mogya mu no te. Wɔfrɛ saa hormone yi B-type natriuretic peptide , anaasɛ `(BNP)` tiawa. Eyi betumi ama wo duruyɛfo anya sɛnea wo koma reyɛ adwuma no ho adwene pa.

Sɛ `(BNP)` dodow a ɛwɔ wo mogya mu no boro sɛnea ɛte daa a, ebetumi akyerɛ sɛ wo koma no ntumi nyɛ adwuma yiye, a ɛkyerɛ sɛ ɛnyɛ mogya a ɛdɔɔso wɔ wo nipadua nyinaa mu. Ɛtɔ da bi a, saa `(BNP)` yi na asaabo no yi fi nipadua no mu, enti sɛ ɔhaw bi wɔ asaabo no mu mpo a, `(BNP)` dodow betumi ayɛ kɛse.

Ade foforo nso ne sɛ, labs binom yɛ sɔhwɛ a ɛte saa ara a wɔfrɛ no ‘aminoterminal pro B-type natriuretic peptide’. Wɔatwa no tiawa sɛ `(NT-proBNP)`. `(BNP)` ne `(NT-proBNP)` sɔhwɛ nyinaa ma nsɛm koro. Nanso, `(NT-proBNP)` botae ahorow betumi ayɛ nea ɛboro `(BNP)` so mpɛn anum kosi du.

Nnuruyɛfo de nhwehwɛmu yi di dwuma de hu sɛ ebia wowɔ tebea bi a wɔfrɛ no komayare anaa . Sɛ wowɔ bi dedaw a, wo duruyɛfo de sɔhwɛ yi bedi dwuma de ahwɛ sɛnea emu yɛ den ne sɛ ebia w’ayaresa no reyɛ adwuma anaa. Ɛtɔ mmere bi a, sɛ wosusuw sɛ wowɔ asiane kɛse mu sɛ wubenya komayare a, ebia wɔbɛyɛ nhwehwɛmu yi nso.

Enti dɛn ne BNP yi?

BNP yɛ protein ahorow pii a ɛboa ma mogya kɔ yɛn nipadua mu no mu biako. Ɛwom sɛ koma na ɛyɛ de, nanso ɛtɔ mmere bi a wɔfrɛ no ‘amemene’ natriuretic peptide efisɛ wodii kan huu no wɔ amemene no mu ntini mu. Susuw ho hwɛ, ɛyɛ nwonwa yiye, ɛnte saa?

Wunim, yɛn koma ne yɛn mogya ntini bom yɛ adwuma de mogya a oxygen pii wom kɔ nipadua no mu nyinaa. Benkum so ahurututu a ɛyɛ adan anan a ɛwɔ koma no mu no mu biako ne nea ɛma mogya no fã kɛse no ara fa koma no mu na ɛde kɔ nipadua no mu. Eyi te sɛ koma no dan titiriw a wɔde pɔmpɔ gu mu no.

Saa benkum ventricle yi ne beae titiriw a wɔyɛ `(BNP)`. Sɛ adesoa a ɛwɔ koma no so no kɔ soro, anaasɛ sɛ koma no wɔ nhyɛso ase esiane ɔhaw bi nti a, `(BNP)` dodow kɔ soro. Koma mu ntini nkwammoaa no yɛ saa nhyɛso yi ho biribi denam `(BNP) a wɔde sie no so.` Afei eyi ma adesoa a ɛwɔ koma no so no so tew na ɛma asaabo no kyerɛ sɛ eyi nkyene ne nsu mfi nipadua no mu. Ɛno ne nea asɛmfua ``Natriuretic`` kyerɛ – ɛkyerɛ biribi a ɛma sodium (nkyene) ne nsuo fi nipadua no mu ntɛmntɛm.

Bere bɛn na wɔyɛ saa BNP sɔhwɛ yi?

Ebia wo duruyɛfo bɛhyɛ nhwehwɛmu yi de ahwɛ sɛ BNP pii wɔ wo mogya mu, a ebetumi akyerɛ sɛ wowɔ koma ne ntini mu yare .Sɛ komayare ho sɛnkyerɛnne bi wɔ hɔ a, akyinnye biara nni ho sɛ wɔbɛyɛ BNP anaa NT-proBNP nhwehwɛmu no.

Ma yɛnhwɛ nea komayare ho sɛnkyerɛnne yɛ.

• Ɛte sɛ ɔfe a ɛyɛ kusuu a sɛ woda a, ɛyɛ den. Ɛtɔ da bi a, ebia wubesusuw sɛ ɛyɛ atiridiinini ara kwa, nanso ɛsono.
• Ɔhome a ɛyɛ den, ahome a ɛyɛ tiaa (Dyspnea), anaa ahome a ɛyɛ tiaa. Sɛ wote nka sɛ wo home yɛ wo yaw bere a woayɛ adwuma ketewaa bi mpo a, ɛsɛ sɛ wohaw wo ho.
• Delirium, tebea a ɛma obi adwene tu fra na ɔyera. Eyi betumi aba wɔn a wɔn mfe akɔ anim titiriw.
• Adwene a ɛyɛ basaa, akisikuru (Syncope). Sɛ wote nka sɛ woatɔ piti te sɛ bere a wosɔre mpofirim a, hwɛ eyi nso yiye.
• Ɔbrɛ paa, na ɔte nka sɛ nkwa nnim. Sɛ ɔbrɛ yi amfi hɔ bere a woada yiye mpo a, ɛno yɛ ɔhaw.
• Koma a ɛbɔ yɛ koma a ɛbɔ ntɛmntɛm a ɛnyɛ ne kwan so. Sɛ wo koma bɔ ntɛmntɛm anaasɛ wote nka sɛ ɛrehuruw abɔ.
• Akisikuru, ɔfe, aduan ho akɔnnɔ a ɛyera.
• Yafunu, nan, nansoaa, ne nan a ɛho ahonhon (edema). Sɛ saa ɔfe yi yɛ kurukuruwa bere a wohwɛ no a, ɛno yɛ sɛnkyerɛnne titiriw.
• Ɛho hia sɛ wɔtaa tow nsu anadwo (Nocturia).

Nea ɛho hia: Sɛ wowɔ saa sɛnkyerɛnne ahorow yi bi a, ɛho hia yiye sɛ wohwehwɛ aduruyɛfo afotu ntɛm ara. Koma a entumi nyɛ adwuma yiye yɛ tebea a ɛde ne nkwa to asiane mu a ehia sɛ wɔsa no ntɛm ara. Yɛsrɛ sɛ mmu w’ani ngu saa sɛnkyerɛnne ahorow yi so.

Koma a entumi nyɛ adwuma yiye kyerɛ sɛ wo koma ntumi nkɔ mogya yiye, ɛnyɛ sɛ wo koma agyae koraa. Kae sɛ sɛ oduruyɛfo bi aka akyerɛ wo dedaw sɛ wowɔ komayare a, wo duruyɛfo no bɛda so ara de sɔhwɛ yi adi dwuma de ahwɛ sɛnea w’ayaresa no reyɛ adwuma yiye.

Ɔkwan bɛn so na saa BNP (anaa NT-proBNP) nhwehwɛmu yi hu koma mu haw ahorow?

Saa `(BNP)` sɔhwɛ anaa `(NT-proBNP)` sɔhwɛ yi susuw `(BNP)` hormone (anaasɛ `(NT-proBNP)`) dodow a ɛwɔ wo mogya mu. Sɛ saa hormone yi dɔɔso wɔ mogya no mu a, ɛkyerɛ sɛ ɛsɛ sɛ koma no yɛ adwumaden kɛse na ama mogya no akɔ. Sɛ yɛbɛka no tiawa a, ɛsɛ sɛ koma no yɛ adwumaden kɛse. Eyi kyerɛ sɛ koma ntini no atrɛw na wɔahyɛ no den.

Dɛn na ɛsɛ sɛ wohwɛ kwan bere a woreyɛ sɔhwɛ no?

Biribi titiriw biara nni hɔ a ɛsɛ sɛ woyɛ de siesie wo ho ma saa `(BNP)` anaa `(NT-proBNP)` sɔhwɛ yi. Ɛho nhia sɛ wudi mmuada, na wubetumi anom nsu. Wo duruyɛfo anaa ɔyarehwɛfo bɛhohoro baabi a ɛfata wɔ wo basa mu na ɔde ade ahyɛ mu. Enti, wobeyi mogya kakra afi ntini bi mu. Ebia wobɛte ɛyaw kakra, te sɛ akuturuku, bere a wɔde ade no hyɛ mu no. Nanso ɛnyɛ yaw kɛse.

Afei, lab no bɛsɔ wo mogya ahwɛ ahwɛ sɛnea wo `(BNP)` (anaasɛ `(NT-proBNP)`) dodow yɛ. Wo duruyɛfo bɛka ho asɛm akyerɛ wo bere a nea afi mu aba no asan aba no.

Bere a woayɛ sɔhwɛ no akyi?

Sɛ wɔtwe mogya no wie a, oduruyɛfo anaa ɔyarehwɛfo de aduru ketewaa bi bɛbɔ wo basa. Ebia wobɛte yaw kakra nka wɔ baabi a wɔde ade no hyɛɛ mu no. Ebia wobɛte nka sɛ woapirapira kakra, na ɛno yɛ ade a ɛfata. Sɛ nea efi mu ba no san ba a, wo duruyɛfo no bɛka ho asɛm akyerɛ wo na wasusuw nea ɛsɛ sɛ woyɛ akyi.

Mfaso bɛn na ɛwɔ sɔhwɛ yi a wobɛyɛ so?

Hwɛ, nhwehwɛmu yi a egye mogya kakraa bi pɛ no betumi ama wo duruyɛfo ahu wo koma akwahosan ho nsɛm a ɛho hia pii. Sɔhwɛ bi a wɔfrɛ no `(BNP)` anaa `(NT-proBNP)` betumi aboa wo duruyɛfo ma wahu sɛ ebia wowɔ komayare anaa . Ebetumi nso ayi nyarewa afoforo a ɛwɔ sɛnkyerɛnne a ɛte saa ara afi hɔ. Sɛ nhwɛso no, ahome a ɛyɛ tiaa betumi afi ahurututu mu haw bi. Saa sɔhwɛ yi betumi aboa wo ma woahu nsonsonoe a ɛda tebea abien yi ntam. Nea ebefi sɔhwɛ yi mu aba no bɛboa wo duruyɛfo no ma wayɛ w’ayaresa no ho nhyehyɛe na wahu sɛnea ayaresa no tu mpɔn.

So asiane ahorow bi wɔ BNP sɔhwɛ yi mu?

Mogya mu nhwehwɛmu abu so yiye na asiane biara nni ho. Mogya kakraa bi pɛ na oduruyɛfo no hia ma nhwehwɛmu yi. Sɛ woyɛ nhwehwɛmu wie a, wo nipadua no befi ase ayɛ mogya bio. Ebia nnipa binom bɛte nka sɛ wɔn adwene mu yɛ wɔn naa kakra anaasɛ wɔn tirim yɛ hare bere a wɔanya mogya awie no. Eyi yɛ ade a ɛfata. Mpɛn pii no, saa nkate yi fi hɔ wɔ simma kakraa bi mu.

Bere tenten ahe na egye ansa na wɔanya BNP sɔhwɛ no mu aba?

Nnuruyɛfo taa yɛ nhwehwɛmu yi bere a wowɔ komayare ho sɛnkyerɛnne ahorow, wɔ baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu anaa ayaresabea. Ɛho hia sɛ wohu komayare (na wopow tebea afoforo) na wofi ase sa yare ntɛm ara sɛnea wubetumi.

Eyi kyerɛ sɛ ɛda adi kɛse sɛ wubenya sɔhwɛ no mu aba ntɛm ara, mpɛn pii no wɔ simma 15 ntam. Eyi yɛ sɔhwɛ a ɛyɛ ntɛm paa. Wo duruyɛfo bɛkyerɛ wo bere a nea ebefi mu aba ne nea ɛbɛkyerɛ.

Dɛn na BNP dodow a ɛnteɛ kyerɛ?

`(BNP)` dodow a ɛfata wɔ obi a onni komayare mu no nnu picogram 100 wɔ mililita biara mu (`pg/mL`). Sɛ `(BNP)` dodow no boro 100 `pg/mL` a, ebetumi ayɛ komayare ho sɛnkyerɛnne.

NT-proBNP dodow a ɛfata no nnu 125 pg/mL wɔ nnipa a wonnii mfe 75 mu na ennu 450 pg/mL wɔ nnipa a wɔadi boro mfe 75 mu. Sɛ NT-proBNP dodow boro 900 pg/mL a, ebetumi nso ayɛ komayare ho sɛnkyerɛnne.

Nanso ma ɛntra w’adwenem sɛ BNP anaa NT-proBNP dodow a ɛfata no betumi ayɛ soronko wɔ onipa biara ho. Ɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa afa wo sɔhwɛ gyinapɛn pɔtee ho, efisɛ wo duruyɛfo no nso besusuw nneɛma te sɛ wo mfe a woadi ne ayaresa tebea afoforo ho.

Worenom beta blockers, ACE inhibitors, ne diuretics (nnuru a ɛma wofa nsu pii) sɛ ayaresa a wɔde sa komayare.Sɛ wonom nneɛma a ɛte sɛɛ a, ebia wo BNP anaa NT-proBNP dodow bɛba fam asen obi a ɔnnom saa nnuru no de. Afei nso, sɛ woyɛ kɛse mmoroso (srade a ɛboro so wɔ nipadua mu) anaasɛ w’asaabo ntumi nyɛ adwuma yiye a, ebia saa dodow yi nso bɛba fam asen sɛnea ɛte daa.

Ɛdenam nea ebefi BNP nhwehwɛmu no mu aba so no, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ nhwehwɛmu afoforo te sɛ electrocardiogram (EKG anaa ECG) . Nea ɛka eyi ho ne sɛ wode sensor ahorow bɛhyɛ wo honam ani de ahwɛ sɛnea anyinam ahoɔden a ɛwɔ wo koma mu no yɛ adwuma, a wɔfrɛ no wo koma bɔ. Eyi betumi aboa wo duruyɛfo ma wahu anaa wasusuw komayare anaa komayare afoforo ho.

Bere bɛn na ɛsɛ sɛ me ne me duruyɛfo kasa fa BNP (anaa NT-proBNP) nhwehwɛmu no ho?

Sɛ wowɔ nsɛmmisa bi fa wo BNP mogya mu nhwehwɛmu aba ho a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa. Nsuro sɛ wobɛbisa sɛ, "Oduruyɛfoɔ, dɛn na saa boɔ a ɛwɔ me BNP amanneɛbɔ so yi kyerɛ?" Wo duruyɛfo bɛkyerɛkyerɛ nea ebefi mu aba no mu akyerɛ wo. Wɔbɛkamfo nhwehwɛmu anaa ayaresa foforo biara a ebia ɛho behia nso akyerɛ.

Enti, nneɛma bɛn na ɛho hia paa a ɛsɛ sɛ yɛkae fi asɛm yi mu?

B-type natriuretic peptide (BNP) sɔhwɛ a wɔsan frɛ no aminoterminal pro B-type natriuretic peptide (NT-proBNP) sɔhwɛ no yɛ sɔhwɛ a ɛma wo duruyɛfo nya wo koma akwahosan ho nsɛm a ɛho hia yiye. Ebetumi aboa ma wɔahu tebea horow te sɛ komayare , ayɛ ayaresa ho nhyehyɛe sɛnea ɛfata, na wɔahu sɛnea saa ayaresa ahorow no tu mpɔn.

Sɛ wowɔ nsɛmmisa bi fa wo nhwehwɛmu no mu aba ho a, ntwentwɛn wo nan ase sɛ wo ne wo duruyɛfo bɛkasa. Sɛ wohu sɛ wowɔ komayare a, nneɛma bi wɔ hɔ a wubetumi ayɛ de atra ase. Eyinom bi ne asetra mu nsakrae, aduan mu nsakrae (te sɛ nkyene ne nsu a wobɛtew so), apɔw-mu-teɛteɛ, ne nnuru a wobɛnom sɛnea wɔakyerɛw ama wo no .

Enti, ɛho hia paa sɛ wohwɛ wo koma so. Sɔhwɛ ahorow a ɛtete saa a wubehu no nso so bɛba wo mfaso kɛse. Ɛmmra sɛ wubenya ahoɔden a wode bɛma wo koma atra apɔw!

` BNP, NT-proBNP, komayare, komayare, mogya mu nhwehwɛmu, komayare ho sɛnkyerɛnne, koma akwahosan