Momma yensua ACTH Stimulation Test no ho ade wɔ ɔkwan a ɛnyɛ den so.

So wotaa te nka sɛ woabrɛ, wo ho ayɛ wo hyew, anaasɛ wo mu duru so tew? Sɛ wokɔ oduruyɛfo nkyɛn a, ebia obesi gyinae sɛ ɔbɛhwɛ wo hormone ahorow. Ne titiriw no, hormone a wɔfrɛ no cortisol. Enti, sɔhwɛ titiriw a wɔyɛ de hwɛ sɛ wo cortisol dodow yɛ nea ɛfata ne ACTH Stimulation Test. Ɛwom sɛ ebia edin no bɛyɛ te sɛ nea ɛyɛ den kakra de, nanso nokwarem no, ɛyɛ mmerɛw koraa. Momma yɛnka ne nyinaa ho asɛm nnɛ.

Sɛ yɛbɛka no tiawa a, dɛn ne saa ACTH Stimulation Test yi?

Eyi yɛ aduruyɛ mu sɔhwɛ. Sɛ yɛbɛka no pɛpɛɛpɛ a, ɛhwɛ sɛnea w’akwaa abien a wɔfrɛ no adrenal glands no yɛ wɔn ade wɔ hormone bi a wɔfrɛ no ACTH (Adrenocorticotropic hormone) a efi yɛn amemene mu ba no ho. So eyi te sɛ nea ɛyɛ basaa kakra? Okay, momma yensusuw ho saa kwan yi so.

Fa no sɛ pituitary gland a ɛwɔ w’amemene mu no te sɛ adwumakuw kɛse bi sohwɛfo. Adrenal gland nketewa abien a ɛwɔ w’asaabo atifi no te sɛ adwumayɛfo baanu a wɔreyɛ adwuma wɔ saa adwumakuw no mu.

Sɛ ɔhwɛfoɔ (pituitary gland) pɛ sɛ ɔyɛ biribi a, ɛde nkrasɛm bi a wɔfrɛ no ‘ACTH’ kɔma adwumayɛfoɔ (adrenal glands). Sɛ wonya saa nkrasɛm yi a, adwumayɛfo (adrenal glands) no yɛ hormone bi a wɔfrɛ no ‘cortisol’ na woyi no kɔ nipadua no mu. Saa cortisol yi yɛ hormone a ɛho hia yiye ma yɛn nipadua. Ɛboa wɔ nneɛma pii mu te sɛ adwennwen a wodi so, asikre dodow a ɛwɔ mogya mu a wodi so, ne mogya mmoroso a wodi so.

Enti, nea ACTH Stimulation Test yɛ ne sɛ yɛde ACTH hormone a wɔayɛ no akyi (a wɔfrɛ no cosyntropin) gu wo nipadua mu na yɛhwɛ sɛ wo adrenal glands (adwumayɛfo) yɛ ho biribi na ɛyɛ cortisol yiye anaa.

Wɔde sɔhwɛ yi di dwuma titiriw de hu tebea bi a wɔfrɛ no ‘adrenal insufficiency’ . Eyi kyerɛ sɛ adrenal ntini no ntumi nyɛ cortisol a ɛdɔɔso. Wɔakyekyɛ eyi mu abiɛsa.

Tebea bɛn mu na oduruyɛfo no ka kyerɛ wo sɛ yɛ nhwehwɛmu yi?

Ebia nneɛma pii nti na wo duruyɛfo betumi akamfo nhwehwɛmu yi akyerɛ.

• Sɛ mogya mu nhwehwɛmu bi a atwam kyerɛ sɛ cortisol dodow sua a: Sɛ woayɛ mogya mu nhwehwɛmu esiane biribi foforo nti a ɛkyerɛ sɛ cortisol dodow sua a, wobetumi aka akyerɛ wo sɛ yɛ nhwehwɛmu yi de si so dua.
• Sɛ wowɔ sɛnkyerɛnne ahorow a ɛkyerɛ sɛ adrenal insufficiency: Sɛnea yɛadi kan aka ho asɛm no, sɛ wowɔ sɛnkyerɛnne ahorow te sɛ ɔbrɛ bere nyinaa, wo mu duru a ɛso tew, yafunu mu yaw, akisikuru, adwenemhaw, ne mogya mmoroso a ɛba fam a, wɔyɛ nhwehwɛmu yi de hu sɛ ebia tebea yi na ɛde ba anaa.
• Sɛ woanom steroid bere tenten a: Sɛ wode nnuru a ɛma glucocorticoid te sɛ prednisone di dwuma bere tenten a, ebia wo pituitary ne adrenal glands no begyae adwumayɛ bere tiaa bi. Enti, sɛ wugyae aduru no nom wie a, wɔyɛ nhwehwɛmu yi nso de hwɛ sɛ ntini no reyɛ adwuma yiye bio anaa.

Ɔkwan bɛn so na ɛsɛ sɛ wusiesie wo ho ansa na woayɛ sɔhwɛ?

Eyi ho hia paa. Ɛsɛ sɛ wudi wo duruyɛfo akwankyerɛ akyi pɛpɛɛpɛ. Mpɛn pii no, wubetumi aka nsɛm a ɛte sɛɛ.

• Mmuadadi: Ebia wɔbɛka akyerɛ wo sɛ nnidi anaa nnom biribiara bɛyɛ nnɔnhwerew 6 ansa na wɔayɛ sɔhwɛ no. Nsu nkutoo na wɔma ho kwan.
• Dwumadi anohyeto: Wobetumi aka akyerɛ wo sɛ kwati dwumadi ahorow te sɛ apɔw-mu-teɛteɛ a emu yɛ den nnɔnhwerew 12-24 ansa na wɔayɛ sɔhwɛ no.
• Aduan: Ɛtɔ mmere bi a, wobetumi aka akyerɛ wo sɛ di nnuan a carbohydrates pii wom.
• Nnuru a wubegyae: Nnuru bi a wonom (titiriw steroid cream, nnuru a wɔde home, anaa nnuru a wɔde home) betumi aka nea efi nhwehwɛmu no mu ba no. Enti, ebia wo duruyɛfo bɛka akyerɛ wo sɛ gyae nom bere tiaa bi. Nnyae w’aduru nom da a wunni kan mmisa wo duruyɛfo.

Okay, afei momma yɛnhwɛ nea ɛbɛba da a wɔbɛyɛ sɔhwɛ no.

Eyi nyɛ hu sɛnea ebia wubesusuw no. Wɔtaa yɛ wɔ ayaresabea anaa ayaresabea a oduruyɛfo a ɔhwɛ ntini mu yare so. Nea ɛkɔ so anammɔn biara ni.

1. Mogya a edi kan a wobɛfa: Nea edi kan no, ɔyarehwɛfo bi begye mogya afi ntini bi a ɛwɔ wo basa mu mu. Eyi bɛhwɛ wo mfitiase cortisol dodow ansa na wɔafi nhwehwɛmu no ase.

2. Injection a wɔde bɛma wo: Afei, ɔyarehwɛfo bi bɛma wo injection a synthetic ACTH (cosyntropin) wom. Wɔtaa de eyi kɔ wo nsa ntini mu. Ɛbɛyɛ te sɛ ntɛtea ketewaa bi a ɔrebɔ wo, nanso ebefi hɔ wɔ sikɔne kakraa bi mu.

3. Mogya a ɛto so abien ne abiɛsa: Wɔbɛma wɔafa mogya foforo wɔ simma 30 akyi wɔ aduru no akyi . Afei wɔbɛfa mogya foforo wɔ simma 60 akyi . Eyi bɛkyerɛ cortisol dodow a wo adrenal ntini ahorow no ayɛ fi bere a wɔde aduru no guu wo mu no.

4. Wɔde kɔ aduruyɛdan mu: Wɔde mogya a wɔfa no kɔ aduruyɛdan mu.

Sɛ wotwe wo mogya a, wote nka sɛ worebɔ wo kakra. Ɛno kɔ bere tiaa bi akyi. Ebia wobɛte akuru ketewaa bi nka wɔ baabi a wɔtwee mogya no, na ɛno yɛ ade a ɛfata.

Bere bɛn na nea ebefi mu aba no bɛba na dɛn na wɔbɛka?

Ebetumi adi bɛyɛ dapɛn biako ansa na nea efi sɔhwɛ yi mu aba no asan aba. Nea enti a ɛte saa ne sɛ, sɛ wo nsa ka nea efi mu ba no wie a, wo duruyɛfo no besua ho ade yiye na ɔde atoto wo yare no ho sɛnkyerɛnne ahorow ho de aka asɛm bi.

Dɛn ne nea efi mu ba a ɛfata?

Wɔ obi a ɔwɔ apɔwmuden mu no, bere a wɔde ACTH ahyɛ no akyi no, ɛsɛ sɛ wɔkanyan adrenal ntini no yiye na ɛsɛ sɛ cortisol dodow a ɛwɔ mogya no mu no kɔ soro kɛse. Wo duruyɛfo bɛkyerɛkyerɛ gyinapɛn ahorow a ɛwɔ wo lab amanneɛbɔ mu ne nea ɛfata mu akyerɛ wo.

Dɛn ne Nea Efi Mu Ba a Ɛnyɛ Ne kwan so?

• Adrenal Insufficiency Titiriw (sɛ ɔhaw bi wɔ adrenal glands no ho a): Wɔ obi a ɔwɔ saa tebea yi mu no, sɛ wɔma no ACTH injection mpo a, cortisol dodow no nkɔ soro koraa anaasɛ ɛkɔ soro kakraa bi pɛ. Nea enti a ɛte saa ne sɛ ɔhaw no wɔ adrenal glands no mu, na ɛmfa ho sɛnea wɔde nkanyan kɛse ma fi abɔnten no, entumi nyɛ cortisol.
• Adrenal Insufficiency a Ɛto so Abien (sɛ ɔhaw bi wɔ pituitary gland no ho a): Sɛ pituitary gland no nnyi ACTH bere tenten a, adrenal glands no twetwe nkakrankakra na efi ase nyɛ adwuma (atrophy). Sɛ wɔde ACTH aduru ma onipa a ɔte saa a, adrenal ntini a ɛnyɛ adwuma no ntumi nyɛ ho hwee ntɛm ara. Enti, wɔn cortisol dodow kɔ soro kakraa bi anaasɛ ɛnkɔ soro koraa.

Ɛtɔ mmere bi a, sɛ pituitary gland haw no yɛ nnansa yi ara anaasɛ ɛka no fã bi pɛ a, ebia cortisol dodow bɛkɔ soro kakra. Wo duruyɛfo ne onipa a oye sen biara a obesi eyinom nyinaa ho gyinae.