So wowɔ ‘Blast Cells’ wɔ wo Mogya Amanneɛbɔ mu? Momma yɛnka eyi ho asɛm kɛkɛ (Blast Cells) .

So woahu asɛmfua ‘Blasts’ pɛn bere a worehwɛ wo mogya ho amanneɛbɔ no? Ɛyɛ ade a ɛfata sɛ wobɛte ehu nka kakra na wopɛ sɛ wuhu bere a wuhu no. Efisɛ asɛmfua a yennim yi ka yɛn akwahosan ho nsɛm pii ankasa. Enti ɛnnɛ, momma yɛnka nea saa Blast Cells yi yɛ, sɛnea ɛho hia ma yɛn nipadua, ne nea wɔn dodow a ɛkɔ soro no kyerɛ ho asɛm. Mma ɛnhaw wo, momma yɛnte eyi ase kɛkɛ.

Dɛn ne Blast Cells wɔ nsɛm a ɛnyɛ den mu?

Sɛ yɛbɛka no tiawa a, blast cells yɛ "nkokoaa nkwammoaa" anaa nkwammoaa a ennyinii. Te sɛ akokoaa. Eyinom ne nkwammoaa a akyiri yi enyin, kyerɛ sɛ, enyin, na ɛbɛyɛ nkwammoaa ahorow a yɛn nipadua hia no. Nanso sɛ wo lab amanneɛbɔ no ka “blasts” ho asɛm a, ɛda adi kɛse sɛ ɛkyerɛ mogya mu nkwammoaa a ennyinii . Mogya ho animdefo ne kokoram ho animdefo hwɛ nkwammoaa a ɛpae yi dodow a ɛwɔ wo mogya mu de nya nsɛm a ɛfa nyarewa ahorow a efi mogya mu ho.

Nsonsonoe bɛn na ɛda Stem Cells ne Blast Cells ntam?

Eyi nso yɛ biribi a ɛma nnipa pii adwene tu fra. Susuw stem cells ho sɛ "mfitiase nkwammoaa" a efi biribiara ase. Ɛte sɛ dɔte a ɛyɛ kurukuruwa. Yebetumi de saa dɔte a ɛyɛ kurukuruwa no ayɛ biribiara, te sɛ kuku, kuruwa, biribiara. Saa na stem cells te. Wobetumi abɛyɛ nkwammoaa biara.

Nkwammoaa a ɛpae ne ade a edi hɔ a ɛma saa ntini mu nkwammoaa yi nyin. Seesei yɛafi ase de saa dɔteɛ a ɛyɛ kurukuruwa no ayɛ kukuo, na ɛrenya nsusuiɛ. Afei yɛrentumi nyɛ no kuruwa bio. Enti, blast cell yɛ nkwammoaa a afi ase retu kwan pɔtee bi. Ɛne sɛ, asi gyinae sɛ ɛbɛyɛ mogya mu nkwammoaa kɔkɔɔ, mogya mu nkwammoaa fitaa, anaa mogya mu nkwammoaa kɔkɔɔ. Ɛno nti na wɔsan frɛ blast cells "precursor cells."

Nkwammoaa a ɛpae a ɛwɔ yɛn nipadua mu no dwumadi ne baabi a wɔyɛ

Nkwammoaa a ɛpae yɛ ade biako pɛ wɔ mogya a ɛba yɛn nipadua mu no mu. Yɛfrɛ saa mogya a ɛba yi `Hematopoiesis`. Eyi si wɔ yɛn nnompe mu ntini mu titiriw . Nnompe mu ntini te sɛ yɛn nipadua mu adwumayɛbea a wɔyɛ mogya.

Wɔ saa adwumayɛbea yi mu no, ntini mu nkwammoaa titiriw a wɔfrɛ no `Hematopoietic Stem Cell (HSC)` no ma wonya nkwammoaa a ɛpae ahorow atitiriw abien:

• Myeloblast: Akyiri yi saa nkwammoaa a ɛpae yi nyin bɛyɛ mogya mu nkwammoaa kɔkɔɔ (a ɛde oxygen kɔ), mogya mu nkwammoaa fitaa ahorow bi (granulocytes - a ɛko tia ɔyare mmoawa), ne mogya nkwammoaa (a ɛboa ma mogya no tu).
• Lymphoblast: Akyiri yi saa nkwammoaa a ɛpae yi nyin bɛyɛ lymphocytes, mogya mu nkwammoaa fitaa foforo a ɛho hia (a ɛyɛ nipadua no mu tumi a ɛko tia nyarewa no fã titiriw).

Dɛn na ɛma nkwammoaa a ɛpae no kɔ soro?

Ɛsɛ sɛ nkwammoaa a ɛpae no nnu nkwammoaa dodow a ɛwɔ obi a ɔwɔ apɔwmuden nnompe mu ntini mu nyinaa mu 5%. Afei nso, ɛnsɛ sɛ nkwammoaa a ɛpae wɔ obi a ɔwɔ apɔwmuden mogya mu.

Sɛ wowɔ nkwammoaa a ɛpae dodow a ɛkɔ soro wɔ wo nnompe mu anaa wo mogya mu a, ebetumi ayɛ mogya mu kokoram te sɛ mogya mu kokoram ho sɛnkyerɛnne, titiriw sɛ nkwammoaa yi te sɛ nea ɛnteɛ bere a wɔde afiri a wɔde hwɛ nneɛma nketenkete hwɛ no a.

Wubetumi anya eyi ho ntease pa afi pon a ɛwɔ ase ha no so.

So nkwammoaa a ɛpaapae betumi adɔɔso a ɛremma kokoram mma?

Yiw, wubetumi. Eyi ho hia paa. Ɛnyɛ bere nyinaa na nkwammoaa a ɛpae a ɛkɔ soro no kyerɛ kokoram. Tebea ne ayaresa ahorow bi a ɛnyɛ kokoram nso betumi ama nkwammoaa a ɛpae akɔ mogya no mu bere tiaa bi.

• Nyarewa a Ɛyɛ Aniberesɛm: Sɛ nipadua no nya ɔyare mmoawa a emu yɛ den te sɛ `Sepsis` a, yɛn nipadua no fi ase yɛ mogya mu nkwammoaa fitaa dodow a ɛboro so de ko tia ɔyare mmoawa no. Saa bere yi de, ebia nkwammoaa a ɛpae a ennyinii no bi nso fi nnompe mu ntini mu kɔ mogya no mu.
• G-CSF ayaresa: Sɛ wɔyɛ kokoram ayaresa te sɛ nnuru a wɔde sa yare a, mogya mu nkwammoaa fitaa no so tew. Saa bere no, wɔde aduru bi a wɔfrɛ no `Granulocyte-colony stimulating factor (G-CSF)` ma de kanyan mogya mu nkwammoaa fitaa a wɔyɛ. Saa aduru a wɔde twitwiw nipadua no mu yi nso betumi ama nkwammoaa a ɛpae a ɛwɔ mogya no mu no dodow akɔ soro bere tiaa bi.
• Nkwammoaa a wɔde si ananmu: Sɛ wɔde ntini mu nkwammoaa si ananmu ma tebea pɔtee bi wie a, ebia nkwammoaa a ɛpae no dodow bɛkɔ soro bere a mogya foforo reyɛ no.

Nanso nea ɛho hia ne sɛ saa nkwammoaa a ɛpae a ɛnyɛ kokoram yi taa hwɛ sɛ wɔwɔ apɔwmuden wɔ afiri a wɔde hwɛ nneɛma nketenkete mu. Wobetumi ayɛ wɔn adwuma bere a wɔanyin no. Wɔ kokoram mu no, yehu nkwammoaa a ɛpae a ɛnyɛ ne kwan so a ɛnteɛ.

Wobɛyɛ dɛn ahwɛ sɛnea nkwammoaa a ɛpae no dodow te?

Nnuruyɛfo de nhwehwɛmu atitiriw pii di dwuma de sua nkwammoaa a ɛpae ho ade.

• Mogya a Wɔde Hyɛ Nneɛma a Ɛwɔ Akyi (PBS): .Nea ɛka eyi ho ne sɛ wode wo mogya a ɛtɔ gu fam bɛpete ahwehwɛ a wɔde twetwe nneɛma so na wode afiri a wɔde hwɛ nneɛma nketenkete ahwɛ. Eyi ma wunya adwene a ɛyɛ den sɛ ebia nkwammoaa a ɛpae wɔ mogya no mu, sɛnea ɛte, ne ɔha biara mu nkyem a ɛyɛ.
• Nnompe mu ntini mu nhwehwɛmu: Eyi ne ɔkwan a eye sen biara a wobɛfa so anya nkwammoaa a ɛpae ho nsɛm a edi mũ na edi mũ sen biara. Nnompe mu ntini mu nhwehwɛmu anaa aspiration hwehwɛ sɛ woyi ade ketewaa bi fi dompe kɛse bi te sɛ asen dompe mu, na wɔfa nnompe mu ntini no bi. Afei wɔsɔ hwɛ wɔ afiri a wɔde yɛ nhwehwɛmu mu de hu nkwammoaa a ɛpae ɔha biara mu nkyem 100 ne sɛnea ɛte ankasa.
• Mogya Dodow a Edi Mu (CBC): Eyi hwɛ wo mogya mu nkwammoaa kɔkɔɔ, mogya mu nkwammoaa fitaa, ne mogya mu nkwammoaa dodow. Sɛ nkwammoaa a ɛpae no dɔɔso a, nkwammoaa a ɛte apɔw yi dodow betumi atew.

Enti sɛ wuhu ‘blasts’ wɔ w’amanneɛbɔ no so a, mma wo ho nnpopo. Ebetumi ayɛ biribi a anibere wom ho sɛnkyerɛnne, na ɛtɔ mmere bi a ebetumi ayɛ bere tiaa mu tebea. Nea ɛho hia sen biara ne sɛ wo ne wo duruyɛfo bɛkasa afa ho na woadi n’afotu akyi. Sɛ ɛho hia a, ɔde wo bɛkɔ mogya ho ɔbenfo nkyɛn.