So wunim Renal Medullary Carcinoma (RMC), kokoram a ɛntaa nsi nanso emu yɛ den a ɛba asaabo mu?

So woate kokoram bi a ɛntaa nsi na ɛyɛ hu a ɛba asaabo mu, titiriw wɔ mmerante ne mmabaa mu ho asɛm pɛn? Ebia ɛnte saa. Eyi ne Renal Medullary Carcinoma, anaasɛ RMC tiawa. Ɛwom sɛ ɛnyɛ nea abu so kɛse de, nanso ebetumi ayɛ nea ɛho hia kɛse sɛ wobɛma w’ani ada hɔ, titiriw wɔ nnipa binom fam. Ɛwom sɛ eyi yɛ asɛmti a anibere wom kakra de, nanso nsuro. Momma yɛnka ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw na ntease wom so nnɛ.

Dɛn ankasa ne RMC?

Sɛ yɛbɛka no tiawa a, Renal Medullary Carcinoma (RMC) yɛ asaabo mu kokoram bi. Nanso ɛntaa nsi koraa, ɛyɛ basabasa paa, na ɛtrɛw ntɛmntɛm. Ɛtaa ba mmerante ne mmabaa mu, titiriw wɔn a wɔwɔ mogya tebea bi a wɔfrɛ no sickle cell disease anaa sickle cell trait.

Sɛ yɛka asaabo mu kokoram ho asɛm a, nea ɛtaa ba ne renal cell carcinoma. RMC nso yɛ renal cell carcinoma no fã ketewaa bi. Nanso asaabo mu kokoram ayarefo 100 biara mu biako mpo nnya RMC tebea yi. Ɛyɛ nea ɛntaa nsi saa.

Dɛn na ɛde kokoram yi ba?

Nyansahufo ne nnuruyɛfo nnya nhuu nea ɛde eyi ba ankasa 100%, nanso ade titiriw biako wɔ hɔ a wɔahu.

Yɛn asaabo wɔ ɔfã bi a wɔfrɛ no renal medulla. Ɛtɔ da bi a obi a ɔwɔ sickle cell tebea no wɔ mogya mu nkwammoaa kɔkɔɔ a ɛsakra yɛ sickle nsusuwii. Sɛ eyi ba a, nkwammoaa no tumi bata ho na esiw mogya ntini a ɛwɔ renal medulla fã a ɛwɔ asaabo no mu no ano.

Saa mogya a esiw kwan yi sɛe nkwammoaa a ɛwɔ saa beae no. Titiriw no, awosu mu abɔde bi a wɔfrɛ no INI1 (a wɔsan frɛ no SMARCB1) a ɛwɔ saa nkwammoaa no mu no sɛe. Saa INI1 awosu mu abɔde yi yɛ adwuma sɛ ɔwɛmfo a esiw nkwammoaa kwan sɛ ɛbɛyɛ kokoram. Sɛ wɔhwehwɛ RMC kokoram nkwammoaa mu a, wonhu saa INI1 awosu mu abɔde yi wɔ wɔn mu. Enti nnuruyɛfo hwɛ sɛ saa INI1 awosu mu abɔde yi wɔ hɔ de si so dua sɛ ebia akisikuru bi yɛ RMC anaasɛ ɛnte saa.

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So me nso mewɔ asiane mu sɛ menya RMC?

Ɛyɛ den sɛ yɛbɛka onii pɔtee a obenya eyi. Sɛ wowɔ obi a ɔwɔ RMC wɔ w’abusua mu a, ɛmma asiane a ɛwɔ hɔ sɛ wubenya bi no nkɔ soro. Ɛno kyerɛ sɛ ɛnyɛ biribi a ɛkɔ so wɔ mmusua mu.

Asiane titiriw ne mogya mu yare a wɔfrɛ no sickle hemoglobinopathy. Ɛne sɛ, sɛ wowɔ sickle cell yare anaa sickle cell su. But very rarely , nnipa a wonni saa tebea horow yi nso betumi anya RMC. Wɔfrɛ no “renal cell carcinoma, a wɔmfa medullary phenotype nkyekyɛ mu” (RCCU-MP).

Sɛ wohwɛ akontaabu no a:

• Ɛtaa ba mmarima so sen mmea.
• Ɛtaa ka asaabo nifa no kɛse.
• Mpɛn pii no, wohu yare no wɔ wɔn mmofraase, a wɔadi fi mfe 11 kosi 39.

Ɛho hia sɛ mmerante ne mmabaa, titiriw wɔn a wɔwɔ sickle cell yare anaa sickle cell su no, hu saa sɛnkyerɛnne ahorow yi, efisɛ sɛ wohu ntɛm a, ebetumi ama ayaresa ayɛ mmerɛw. Sɛ yare no ho sɛnkyerɛnne bi ba a, kɔ oduruyɛfo nkyɛn ntɛm ara.

Dɛn ne RMC ho sɛnkyerɛnne ahorow?

Yare yi ho sɛnkyerɛnne ahorow pii wɔ hɔ a ɛtaa ba. Sɛ wowɔ eyinom mu biako anaa nea ɛboro saa a, ɛbɛyɛ papa sɛ wobɛhwehwɛ aduruyɛfo afotu ntɛm ara sɛnea wubetumi.

Ɔkwan bɛn so na oduruyɛfo hu eyi?

Sɛ woka wo yare no ho sɛnkyerɛnne kyerɛ yɛn a, ade a edi kan a oduruyɛfo no bɛyɛ ne sɛ ɔbɛhwehwɛ wo mu. Afei wubetumi adi anammɔn yi akyi.

1. 1. Nnipa a wɔte saa.Ultrasound scan: Eyi betumi ama woahu sɛ ebia biribi te sɛ akisikuru wɔ asaabo no mu anaa.

2. CT anaa MRI scan: Sɛ wosusuw sɛ akisikuru bi wɔ hɔ a, wobetumi ahyɛ sɛ wɔnyɛ CT scan anaa MRI na ama wɔahu akisikuru no ho mfonini pefee. Oduruyɛfo no gyina mfonini ahorow yi so betumi ahu sɛnea ɛbɛyɛ yiye sɛ obi benya kokoram.

3. Biopsy: Sɛ wosusuw denneennen sɛ kokoram a, wɔyɛ nhwehwɛmu yi de si so dua. Nea ɛka eyi ho ne sɛ wɔde ade fɛfɛ bi bɛhyɛ baabi a asaabo no mu akisikuru no wɔ, agye ntini ketewaa bi na wɔde afiri a wɔde hwɛ nneɛma nketenkete ahwɛ mu.

4. Awosu mu nhwehwɛmu: Wɔhwɛ nkwammoaa a wogye fii biopsy no mu sɛ ebia INI1 awosu mu abɔde a ɛko tia kokoram a yɛadi kan aka ho asɛm no wɔ hɔ anaa.

• Sɛ INI1 gene no nni hɔ a , wɔkyerɛ sɛ ɛyɛ RMC.
• Sɛ INI1 gene no nni hɔ na ɔyarefo no nni sickle cell tebea a, wohu sɛ ɛyɛ RCCU-MP.
• Sɛ INI1 gene no wɔ hɔ a , ɛnyɛ RMC, na mmom ɛyɛ akisikuru soronko.

Dɛn ne ayaresa ahorow a wɔde sa eyi?

Esiane sɛ RMC yɛ kokoram a ɛtrɛw ntɛmntɛm na ɛyɛ hu nti, ɛsɛ sɛ ayaresa no yɛ ntɛmntɛm na ɛyɛ den saa ara.

• Nnuru a wɔde sa yare: Eyi ne ayaresa a edi kan a wɔtaa yɛ. Nea ɛka ho ne nnuru a ekum kokoram nkwammoaa a wɔde ma nipadua no.
• Oprehyɛn: Woyi kokoram akisikuru no ne ebia asaabo a ayɛ no yaw no fi hɔ.
• Radiation Therapy: Wɔde mframa a ano yɛ den sɛe kokoram nkwammoaa.

Esiane sɛ saa yare yi ho yɛ na nti, nhwehwɛmu da so ara kɔ so. Nyansahufo hwehwɛ ayaresa foforo a etu mpɔn kɛse ma RMC bere nyinaa.

So ɔkwan bi wɔ hɔ a wɔbɛfa so asiw RMC ano?

Nea ɛyɛ awerɛhow no, mprempren ɔkwan biara nni hɔ a wonim a wɔbɛfa so asiw RMC ano, na nhwehwɛmu biara nni hɔ a wɔde behu ansa na sɛnkyerɛnne ahorow no ada adi.

Ade a eye sen biara a wubetumi ayɛ ne sɛ wubehu . Sɛ wunim sɛ wowɔ sickle cell yare anaa sickle cell su a, hwɛ yiye wɔ sɛnkyerɛnne ahorow a yɛaka ho asɛm wɔ atifi hɔ no ho. Sɛ wowɔ biribi a ɛhaw wo a, kɔ wo duruyɛfo nkyɛn ntɛm ara.

Mpɛn pii no, bere a wobehu yare yi no, na kokoram no atrɛw akɔ ntini a ɛma mogya tu anaa akwaa afoforo te sɛ ahurututu, mmerɛbo, ne nnompe mu dedaw. Enti, sɛ wohu ntɛm a, ɛno ne ɔkwan a eye sen biara a wobɛfa so anya nea eye sen biara.