So wo ba no wɔ saa sɛnkyerɛnne ahorow yi? Momma yensua Hypothalamic Hamartoma (HH), amemene mu akisikuru a ɛntaa nsi ho ade

So ɛtɔ mmere bi a wo ba kumaa no fi ase serew denneennen mpofirim a ntease biara nnim? So saa serew no yɛ nea wontumi nsiw ano, te sɛ akisikuru? Anaasɛ wo babea anaa wo babarima reda sɛnkyerɛnne ahorow adi sɛ wanyin ntɛm? Ɛyɛ ade a ɛfata sɛ wo, sɛ ɔwofo, sɛ wuhu saa nneɛma yi a, wobɛte ehu ne dadwen pii nka. Ɛnnɛ yɛreka amemene tebea bi a ɛntaa nsi koraa, nanso akyinnye biara nni ho sɛ ɛho hia sɛ yehu, a ebetumi de saa sɛnkyerɛnne ahorow yi aba ho asɛm.

Dɛn ankasa ne Hypothalamic Hamartoma (HH)?

Sɛ yɛbɛka no tiawa a, ɛyɛ onyin a ɛte sɛ akisikuru a ɛnyɛ kokoram a ɛkɔ yɛn amemene no mu tɔnn, wɔ ɔfã bi a ɛho hia yiye a wɔfrɛ no hypothalamus, a ne kɛse bɛyɛ sɛ almond.

Susuw hypothalamus ho sɛ ade titiriw a ɛhwɛ yɛn nipadua so. Ɛdi dwuma titiriw ma biribiara kari pɛ (homeostasis), na ɛka hormone nhyehyɛe ne ntini a ɛwɔ yɛn nipadua mu no nyinaa bom.

Nneɛma a hypothalamus no di so no bi ne:

• Mogya mmoroso
• Nipadua mu hyew
• Adwennwen, dadwen ho nkate
• Ɔkɔm ne sukɔm
• Nnuru a ɛma nipadua no nya ahoɔden fi pituitary gland no mu
• Dae ne nyane kyinhyia ahorow

Saa HH akisikuru yi fi ase nyin bere a abofra da so ara wɔ awotwaa mu no . Bere a abofra no amemene nyin no, saa akisikuru yi nyin nkakrankakra. Nanso mma ɛnhaw wo, ɛntrɛw nkɔ amemene no afã afoforo anaa nipadua no akwaa afoforo. Mpɛn pii no, akisikuru biako pɛ na ɛwɔ hɔ, nanso ɛntaa mma sɛ pii betumi aba.

Nea eye sen biara ne sɛ mprempren ayaresa pa wɔ hɔ a wɔde siw sɛnkyerɛnne ahorow a tebea yi de ba no so.

Dɛn ne tebea yi ho sɛnkyerɛnne?

Saa sɛnkyerɛnne ahorow yi nyɛ pɛ wɔ abofra biara fam na ebetumi ayɛ soronko wɔ abofra biara mu. Nanso, sɛnkyerɛnne ahorow akuw atitiriw abiɛsa na wotumi hu.

1. Mmabun a Ɛba Ntɛm

Eyi yɛ yare yi ho sɛnkyerɛnne atitiriw no mu biako. Sɛ yɛbɛka no tiawa a, abofra no nipadua fi ase nyin wɔ nna mu ntɛm koraa sen mfe a ɛsɛ sɛ odi. Wɔfrɛ eyi ``Central Precocious Puberty''. Eyi ba efisɛ amemene no de nsɛnkyerɛnne kɔma ma ɛyɛ nna mu nkwaadɔm ntɛm pa ara.

Mpɛn pii no, sɛ abeawa bi da ne babunbere ho sɛnkyerɛnne adi ansa na wadi mfe 8 na abarimaa bi nso adi mfe 9 a, ɛsɛ sɛ ɛhaw yɛn.

2. Akisikuru a ɛma obi ho kyere no

Akisikuru nso abu so wɔ saa yare yi mu. Afei nso, akisikuru soronko bi a ɛtaa ba wɔ saa yare yi mu. Wɔfrɛ no Gelastic seizure .

Saa serew yi nyɛ anigyesɛm a esisi. Ebia ɛbɛkyɛ sikani kakraa bi pɛ, nanso ebetumi aba mpɛn pii da biara, na wɔ tebea horow bi a emu yɛ den mu no, mpɛn pii dɔnhwerew biara. Mpɛn pii no, saa akisikuru yi fi ase ansa na abofra no adi afe biako . Nanso ɛso tew nkakrankakra bere a wadi mfe 10 akyi.

Nea ɛka ho no, wotumi hu akisikuru ahorow afoforo nso.

• Atonic seizures (drop attacks): Nipadua a ɛyera mpofirim, ntini a ɛyɛ mmerɛw, na ɛtɔ fam.
• Dacrystic seizures: Su a wontumi nni so, ɛkɔ so su a ntease biara nnim, te sɛ serew.
• Tonic-clonic seizures: Sɛnea yɛn nyinaa nim no, akisikuru kɛse a ɛma obi ntumi nhu hwee na nipadua no wosow.

3. Ntini mu Nsɛnkyerɛnne ne Suban mu Nsakrae

Esiane sɛ hypothalamus yɛ amemene no fã bi a ɛboa ma yedi yɛn nkate ne yɛn nneyɛe so nti, HH betumi aka abofra nneyɛe, ne nkate, ne sɛnea osua ade. Ɔhaw ahorow a ebetumi aba no bi ne:

• Ɛyɛ den sɛ wobɛma w’adwene akɔ so ne dwumadi a ɛtra so (Attention-deficit/hyperactivity disorder - ADHD) .
• Suban bɔne, atirimɔdensɛm `(Abrabɔ mu basabasayɛ)`
• Adwene mu dɛmdi
• Adwene mu haw ahorow
• Ɔsɔretia-a wɔsɔre tia ɔhaw
• Suban a wɔde yɛ ade
• Bere tiaa mu ɔhaw ahorow a ɛma obi kae ade

So hypothalamic hematomas ahorow bi wɔ hɔ?

Yiw, wobetumi akyekyɛ akisikuru yi mu abien titiriw a egyina beae a ɛwɔ wɔ hypothalamus no mu ne sɛnkyerɛnne ahorow a ɛde ba no so.

1. Intrahypothalamic lesion: Wɔ saa su yi mu no, akisikuru no wɔ hypothalamus no akyi. Eyi sɛe amemene no anyinam ahoɔden dwumadi, na ɛde asiane kɛse ba sɛ obenya akisikuru ne nneyɛe mu haw ahorow .

2. Parahypothalamic lesion (pedunculated lesion): Ɛha na akisikuru no wɔ hypothalamus no anim. Eyi ne sɛnkyerɛnne titiriw a wohu esiane mmerantebere ne mmabaabere ntɛm nti .

Ebia mmofra binom bɛbom anya ahorow abien no nyinaa.

Dɛn na ɛde tebea yi ba?

Biribiara nni hɔ pɔtee biara a ɛde eyi bae de besi nnɛ . Na ɔkwan biara nni hɔ a wɔbɛfa so asiw ano. Mpɛn pii no, ɛba kwa. Ɛno kyerɛ sɛ ɛnyɛ awosu mu mpɛn pii. Hokwan a ɛwɔ hɔ sɛ wo ba benya bi no sua koraa efisɛ obi wɔ w’abusua mu.

Nanso nnansa yi nhwehwɛmu ada no adi sɛ nsakrae bi aba awosu mu abɔde `GLI3` mu wɔ saa akisikuru yi ntini mu. Nhwehwɛmu da so ara kɔ so wɔ eyi ho.

Wɔahu nso sɛ awosu mu tebea bi a wɔfrɛ no ``Pallister-Hall syndrome (PHS)'' betumi ne HH wɔ abusuabɔ bi.

Ɔkwan bɛn so na wobetumi ahu yare yi pɛpɛɛpɛ?

Ɛda adi sɛ wo duruyɛfo bɛkra sɛ wɔnyɛ w’amemene no MRI (Magnetic Resonance Imaging) scan mfa nkyerɛ sɛ woahu sɛ wowɔ wo yare no. MRI tumi ma amemene no ho mfonini a emu da hɔ yiye na ɛkɔ akyiri.

Sɛ wo ba no nya akisikuru a, wɔkamfo kyerɛ sɛ wɔnyɛ EEG (Electroencephalogram) nhwehwɛmu nso. Eyi sɔ anyinam ahoɔden dwumadi a ɛwɔ amemene no mu hwɛ.

Nea ɛka ho no, wobetumi ayɛ ntini mu nhwehwɛmu de ahwɛ sɛnea abofra no susuw nneɛma ho, sɛnea osua ade, ne sɛnea ɔkae ade no, na wobetumi ayɛ mogya mu nhwehwɛmu de ahwɛ sɛnea hormone dodow te. Nsɛm a efi nhwehwɛmu ahorow yi mu no betumi aboa kɛse wɔ ayaresa ho nhyehyɛe a wɔbɛyɛ mu.

Ɔkwan bɛn so na wɔsa?

Botae atitiriw abien na ɛwɔ HH ayaresa mu. Biako ne sɛ wobedi mmerantebere ne mmabaabere a ɛba ntɛm so, na biako nso ne sɛ wobedi akisikuru so.

• Wɔ mmerantebere ne mmabaabere mfiase ho: Wɔde nnuru di dwuma ma eyi. Wɔde nnuru a ɛma hormone agonists a ɛma gonadotropin ma no ma sɛ aduru a wɔde twitwiw nipadua no mu ɔsram biara. Eyi na ɛma nkwaadɔm a ɛma nipadua no yɛ adwuma no fi nipadua no mu na ɛhwɛ mmabunbere ho sɛnkyerɛnne ahorow so. Sɛ abofra no du mfe a ɛsɛ sɛ ɔbabunbere mpɛn pii no a, oduruyɛfo no begyae aduru no.
• Wɔ akisikuru ho: ‘Gelastic seizures’ a yɛadi kan aka ho asɛm no ntumi nyɛ wɔn ade yiye wɔ nnuru a wɔde ko tia akisikuru a wɔtaa de di dwuma no ho. Enti , mpɛn pii no, ɛho hia sɛ wɔyɛ oprehyɛn anaa akwan titiriw afoforo .

Akwan titiriw a wɔfa so yi mogya mu ntini no anaasɛ wɔsɛe no de siw akisikuru ano no bi wɔ ase ha.

Bio nso, wobetumi de nhomasua mmoa titiriw, suban ho ayaresa, ne nnuru ama wɔ sukuu mu de adi abofra no suban ne adesua mu haw ahorow ho dwuma.

Bere bɛn na ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn?

Sɛ́ ɛna anaa agya no, wunim wo ba no yiye. Enti, sɛ wuhu nsakrae anaa sɛnkyerɛnne ahorow bi a ɛyɛ soronko wɔ wo ba no ho a, mmu w’ani ngu so . Sɛ wo ba no wɔ sɛnkyerɛnne ahorow a edidi so yi mu biara a, hwehwɛ aduruyɛfo afotu ntɛm ara.

• Akisikuru: Titiriw no, serew a ɛyɛ hu a ntease biara nnim.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anyin ntɛm: Sɛnea yɛadi kan aka ho asɛm no, nneɛma te sɛ nhwi nyin ne ne nne sesa.
• Adesua mu haw ahorow: wontumi mfa n’adwene nsi biribi so, nsakrae a ɛba wɔ nkae mu.
• Suban mu nsakrae: Nneɛma nketenkete ho a wo bo fuw, ɔyɛ basabasa.
• Nkwammoaa a ɛnkari pɛ: sukɔm a ɛtra so, ɔkɔm mu nsakrae, adwene a ɛsakra mpofirim.

Ebia wobɛte ehu nka kɛse bere a wuhu sɛ wo ba no wɔ HH no. Nanso kae sɛ mprempren ayaresa a etu mpɔn yiye wɔ hɔ a wɔde sa eyi. Wo ne wo duruyɛfo nkasa na paw ayaresa a eye ma wo ba no.