Sɛ wohu sɛ wo anaa wo dɔfo bi anya kokoram a, ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wopɛ sɛ wuhu ayaresa a wɔde bɛma wo no kɛse, na ebia wo ho yeraw wo mpo. Titiriw sɛ wɔkyerɛw wo aduru pɔtee bi te sɛ Ivosidenib (Tibsovo) a, ɛho hia yiye sɛ wuhu nea ɛyɛ ankasa. Enti ɛnnɛ, momma yɛnka saa aduru yi a wɔfrɛ no Ivosidenib ho asɛm, tiawa koraa, wɔ kasa a wubetumi ate ase mu.
Aduru bɛn na Ivosidenib yɛ?
Sɛ yɛbɛka no tiawa a, eyi yɛ "ayaresa a wɔde wɔn ani asi so" bi. Ɛde n’ani si protein pɔtee bi a ɛwɔ kokoram nkwammoaa mu so na esiw wɔn kwan. Wɔde saa aduru yi sa tebea abien titiriw.
1. Acute Myelogenous Leukemia (AML): Eyi yɛ kokoram a ɛba mogya ne nnompe mu ntini mu.
2. Cholangiocarcinoma: Eyi yɛ kokoram a ɛba yɛn nipadua no bile duct nhyehyɛe mu.
Ebia wo duruyɛfo nso bɛkyerɛw saa aduru yi ama tebea afoforo. Sɛ wowɔ nsɛmmisa bi fa eyi ho a, bisa wo duruyɛfo.
Dɛn na ɛsɛ sɛ meka kyerɛ oduruyɛfo no ansa na mafi saa aduru yi ase?
Ansa na wo duruyɛfo bɛkyerɛw saa aduru yi no, ɛsɛ sɛ woka kyerɛ wɔn ampa sɛ wowɔ saa tebea horow yi bi a. Saa nsɛm yi ho hia paa ma w’ahobammɔ.
- Sɛ wowɔ ntini mu yare bi a wɔfrɛ no Guillain-Barre syndrome a .
- Sɛ wowɔ abakɔsɛm a ɛkyerɛ sɛ wowɔ komayare anaa koma a ɛbɔ daa a.
- Sɛ wowɔ asaabo mu yare anaa mmerɛbo mu yare a.
- Sɛ wɔaka akyerɛ wo sɛ sodium, potassium, anaa magnesium dodow a ɛwɔ wo mogya mu no sua a.
- Sɛ woanya akisikuru wɔ ivosidenib anaa aduru foforo biara, aduan, anaa aduru a wɔde yɛ ade ho a.
- Sɛ woanyinsɛn anaasɛ worebɔ mmɔden sɛ wubenyinsɛn a. (Eyi ho hia yiye)
- Sɛ woyɛ ɛna a worema nufu a.
Ɔkwan bɛn so na wɔde aduru no bedi dwuma yiye?
Akwankyerɛ pɔtee a wɔde bedi dwuma wɔ aduru yi a wɔde bedi dwuma ho no ho hia na ama ayaresa no ayɛ yiye.
- Eyi yɛ aduru a wode fa w’ano nom. Fa no sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, bere koro no ara mu da biara .
- Mmu, nbubu, anaa nwe tablet no. Fa nsu mene tablet no nyinaa.
- Wubetumi anom eyi ansa na woadi anaa bere a woadi awie, nanso sɛ wo yafunu mu yɛ wo yaw a, ɛbɛyɛ papa sɛ wode ka aduan ho.
- Kae! Mfa saa aduru yi nka aduan a srade pii wom ho.
- Ade foforo a ɛho hia! Mfa saa aduru yi nka bobe nsuo ho da.
- Kɔ so nom aduru no kosi sɛ oduruyɛfo no bɛka akyerɛ wo sɛ gyae.
Sɛ wonom nnuru pii a, dɛn na woyɛ?
Sɛ wususuw sɛ woanom nnuru pii a, ntwentwɛn wo nan ase. Ntɛm ara frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea , anaa kɔ ayaresabea a ɛbɛn wo no Ayaresa a Ɛho Hia Ntɛmntɛm (ETU) .
Na sɛ mepa nnuru dodow bi nso ɛ?
Sɛ wo werɛ fi sɛ wobɛnom dodow bi a, fa no bere a wokae ara pɛ, sɛ ɛboro nnɔnhwerew 12 kosi wo dodow a edi hɔ a wobɛnom nkutoo a. Sɛ ɛkame ayɛ sɛ bere aso sɛ wobɛma wo dodow a edi hɔ (a ennu nnɔnhwerew 12) a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru abien bere koro mu da.
Sɛ wofe bere a woanom aduru no awie a, nnom aduru foforo. Fa wo dodow a edi hɔ no wɔ bere a wɔahyɛ da ayɛ no mu.
Nnuru afoforo a ebetumi ne saa aduru yi adi nkitaho (Drug Interactions) .
Ivosidenib yɛ aduru a ɛtumi ne nnuru foforɔ di nkitaho, enti ka nnuru a worenom nyinaa (a vitamin ne nhabannuru ka ho) kyerɛ wo duruyɛfoɔ.
| Nnuru ahorow a wɔde di dwuma | Nsɛm a wɔakyerɛw ne nhwɛso ahorow |
|---|---|
| Nnuru a ɛnsɛ sɛ wɔnom da | Cisapride, Dronedarone, Pimozide, Thioridazine a wɔde yɛ nnuru a wɔde sa yare |
| Nnuru bi a wɔde ko tia HIV anaa Hepatitis | Eyinom betumi asesa Ivosidenib nkɛntɛnso. |
| Nnuru a wɔde sa fungal yare mmoawa | Sɛ nhwɛso no: Fluconazole, Itraconazole, Ketoconazole a wɔde di dwuma |
| Nnuru a wɔde sa koma bɔ a ɛnbɔ daa | Sɛ nhwɛso no: Amiodarone, Quinidine, Propafenone a wɔde di dwuma |
| Nnuru a wɔde sa akisikuru/ akisikuru | Sɛ nhwɛso no: Carbamazepine, Phenobarbital, Phenytoin a wɔde yɛ aduru |
| Mmea hormone ne nnuru a wɔde siw awo ano | Ebia nnuru a wɔde siw awo ano a etu mpɔn no so bɛtew. |
| Ɔhotefo Yohane a ɔyɛ ɔkraman | Ɛwom sɛ eyi yɛ nhabannuru de, nanso ebetumi ne nnuru adi nkitaho. |
| Nnuru afoforo a ɛma koma no bɔ QT ntam kwan kyɛ | Eyi betumi ama koma no nnyigyei mu nsakrae a asiane wom aba. |
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom aduru no
- Nsunsuanso bɔne a ɛtaa ba: Ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo ti ayɛ wo yaw kakra anaasɛ w’adwene mu yɛ wo naa bere a worenom aduru yi no. Nea enti a ɛte saa ne sɛ kokoram ayaresa betumi aka kokoram nkwammoaa ne nkwammoaa a wɔwɔ apɔwmuden nyinaa. Sɛ wunya ɔhaw biara a, ka kyerɛ wo duruyɛfo. Kɔ so nom aduru no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.
- Mogya mu nhwehwɛmu: Wo duruyɛfo bɛhyɛ sɛ wɔnyɛ wo mogya mu nhwehwɛmu daa bere a worenom aduru yi. Ɛho hia sɛ worentwa wɔn so.
- Nyinsɛn ne awo: Eyi yɛ asɛm a ɛho hia paa.
Ɛsɛ sɛ wokwati sɛ wubenyinsɛn bere a worenom aduru yi no. Sɛ woyɛ ɔbea, worebɔ mmɔden sɛ wubenyinsɛn, anaa wususuw sɛ woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Sɛ woyɛ ɔbarima a, ɛsɛ sɛ wokwati sɛ wobɛwo abofra bere a worenom aduru yi. Eyi betumi apira akokoaa a ɔhyɛ yafunu mu no kɛse.
- Awo ano aduru: Ebia awo ano aduru rentumi nyɛ adwuma yiye bere a worenom saa aduru yi, enti hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa afa awo ano aduru foforo a wode bedi dwuma ho (sɛ nhwɛso no, kɔndɔm).
- Nufu a Woma: Kwati sɛ wobɛma wo ba no nufu bere a worenom saa aduru yi ne ɔsram biako wɔ dodow a etwa to no akyi.
Dɛn ne nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, Ivosidenib betumi de ɔhaw ahorow aba. Ebi yɛ nketewa, bere a afoforo nso hwehwɛ sɛ wodi ho dwuma ntɛm ara.
| Nneɛma bɔne a efi mu ba no mu nkyekyɛmu | |
|---|---|
| Nsunsuanso bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara | |
| Nneɛma a ɛma obi ho yɛ no hyew | Wora mu akisikuru, ɛyaw, anim, ano anaa tɛkrɛma a ɛho ahonhon. |
| Edema a ɛma obi ho yɛ hyew | Mu duru a ɛkɔ soro mpofirim; nansoaa, anan, nsa a ɛho ahonhon; ɛyɛ den sɛ wobɛhome. |
| Nsakrae a ɛba koma a ɛbɔ mu | Ɔhome a ɛyɛ den, koko mu yaw, adwenemhaw, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, ɔtopae. |
| Nsɛnkyerɛnne afoforo a anibere wom | Atiridiinini, aniwa a ɛsakra, ɛyɛ den sɛ wobɛtow nsu, ano a ɛyɛ kuru, ɛyaw anaa akwaa a ɛyɛ mmerɛw, ɔbrɛ a ɛtra so. |
| Nneɛma bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo sɛ ɛkɔ so anaasɛ ɛhaw adwene a | |
| Nnuan a wɔyam no mu haw ahorow | Akisikuru, akisikuru, akisikuru, ɔfe, yafunu mu yaw. |
| Nneɛma nketenkete afoforo | Aduan ho akɔnnɔ a ɛyera, nkwaa mu yaw, ntini mu yaw. |
Wobɛyɛ dɛn akora w’aduru no so yiye?
- Fa sie baabi a mmofra ne afieboa ntumi nkɔ hɔ.
- Fa sie wɔ dan mu hyew (a ɛwɔ digrii Celsius 20-25 ntam).
- Tow nnuru a ne bere atwam gu. Bisa wo duruyɛfo no ɔkwan pa a wobɛfa so atow agu. Ebia wubetumi ahu nhyehyɛe ahorow a wɔde san fa nnuru ho asɛm.
Nkrasɛm a Wɔde Kɔ Fie
- Mene Ivosidenib aduru no nyinaa, a wunbubu, nbubu, anaa nwe. Fa no bere koro mu da biara da.
- Kwati sɛ wobɛnom aduru yi ne bobe nsu ne nnuan a srade wom koraa.
- Ka nnuru afoforo, vitamin, ne nhabannuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
- Kwati sɛ wubenyinsɛn bere a worenom aduru yi. Fa awo ano aduru foforo di dwuma.
- Sɛ wunya ɔhaw ahorow a emu yɛ den te sɛ wo koko mu yaw, ɛyɛ den sɛ wobɛhome, anaasɛ wo hohoro a, hwehwɛ ayaresa ntɛm ara.
- Saa aduru yi yɛ wo nkutoo dea. Mfa nkyerɛ afoforo da.
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