So worehyia srade a ɛwɔ wo nipadua no afã horow? Momma yensua Lipodystrophy ho ade!

So woahu, anaasɛ woanya osuahu sɛ srade a ɛso tew mpofirim wɔ wo nipadua no afã horow bi, anaasɛ srade a ɛkɔ soro a wompɛ wɔ mmeae afoforo? Ɛtɔ mmere bi a eyi betumi ayɛ nea wontumi nsusuw ho. Ɛnnɛ yɛrebɛka tebea yi ara ho asɛm. Wɔ aduruyɛ mu no, wɔfrɛ eyi Lipodystrophy . Mma ɛnhaw wo, ɛwom mpo sɛ ebia edin no bɛyɛ te sɛ nea ɛyɛ nwonwa de, nanso momma yɛnka ho asɛm tiawa.

Dɛn ne Lipodystrophy?

Sɛ yɛbɛka no tiawa a, Lipodystrophy yɛ srade ntini a ɛyera koraa anaa ne fã bi, nea yɛtaa frɛ no "srade," wɔ mmeae bi, anaasɛ srade a ɛboaboa ano wɔ nipadua no mmeae ahorow wɔ ɔkwan a ɛnteɛ so.

Fa no sɛ wo mu duru so retew wɔ wo nipadua no mmeae bi, te sɛ wo nsa ne wo nan, bere a worenya srade a ɛboro so wɔ mmeae te sɛ w’anim ne wo kɔn mu. Eyi ne nea ɛkɔ so wɔ Lipodystrophy mu. Saa tebea yi ahorow wɔ hɔ, ebinom fi awosu mu (i.e., biribi a wɔde awo yɛn), bere a afoforo nso nya akyiri yi esiane aduruyɛ mu tebea afoforo nti. Ɛsono sɛnea emu biara ka nnipa na ɛsono ne sɛnkyerɛnne ahorow.

Dɛn nti na srade (adipose tissue) ho hia yɛn nipadua saa?

Afei ebia woresusuw sɛ, "Dodow a srade sua no, dodow no ara na eye." Nanso nokwarem no, srade ntini yɛ nnwuma a ɛho hia pii wɔ yɛn nipadua mu. Hwɛ:

• Ahoɔden a yɛde sie: Ɛyɛ saa srade ntini yi mu na wɔkora calories a ɛboro so a yenya fi aduan a yedi mu no so sɛ ahoɔden.
• Ahobammɔ a yɛde ma: Ɛma akwaa ahorow a ɛwɔ yɛn nipadua mu no bɔ yɛn ho ban te sɛ cushion.
• Ɔhyew a yɛbɛkɔ so akura mu: Ɛma nipadua mu hyew kɔ so tra hɔ na ɛbɔ yɛn ho ban fi nneɛma a atwa yɛn ho ahyia a awɔw wom ho.
• Nkwammoaa a ɛma nipadua no yɛ adwuma: Wɔyɛ hormone ahorow pii a ɛho hia te sɛ Leptin na woyi gu mogya no mu.
• Ɔfe a wosiw ano: Ɛboa nso ma wodi ɔfe a ɛwɔ nipadua no mu no so.

Enti, sɛ srade ntini yi yera anaasɛ ɛkɔ hɔ wɔ ɔkwan a ɛnteɛ so esiane lipodystrophy nti a, ɛnyɛ sɛ yɛn honam ani hwɛbea sesa nko, na mmom nipadua no mu nneɛma a ɛho hia a ɛma nipadua no yɛ adwuma no nso sɛe. Nnipa pii a wɔwɔ lipodystrophy no wɔ asiane mu sɛ wobenya nyarewa te sɛ asikreyare ne mogya mu srade dodow a ɛnteɛ.

So lipodystrophy ahorow bi wɔ hɔ?

Yiw, wobetumi akyekyɛ Lipodystrophy mu ayɛ no ahorow abien: awosu ne nea wonya.

Awosu mu Lipodystrophy Ahorow

Eyinom yɛ nea wonya fi awo mu, kyerɛ sɛ, ahorow a ɛba esiane awosu mu nsakrae nti.

• Congenital Generalized Lipodystrophy (CGL): Eyi yɛ Berardinelli-Seip yare.Wɔsan frɛ no. Eyi yɛ tebea a ɛntaa nsi koraa. Wɔ eyi mu no, ɛkame ayɛ sɛ nipadua no mu srade yera koraa anaasɛ ɛyera kɛse. Eyi fi awosu mu dɛmdi bi a ɛwɔ hɔ wɔ awo mu. Mpɛn pii no, wobetumi ahu saa tebea yi wɔ nkwa afe a edi kan no mu.
• Abusua mu Lipodystrophy (FPLD): Eyi nso yɛ awosu mu tebea. Nanso, wɔtaa hu no akyiri yi wɔ asetra mu. Wɔ saa tebea yi mu no, abofra no hwere srade titiriw wɔ ne nan ne ne nsa mu, na ɔboaboa srade pii ano wɔ n’anim ne ne kɔn mu.

Lipodystrophy a Wonya Ahorow

Eyinom yɛ ahorow a ɛsɔre bere a wɔawo yɛn akyi ne yɛn nkwa nna mu esiane nneɛma ahorow nti.

• Acquired Generalized Lipodystrophy (AGL): Wɔsan frɛ no Lawrence syndrome , tebea yi ma srade so tew, mpɛn pii no wɔ anim, kɔn, nsa, ne nan mu. Saa srade a wɔhwere yi betumi asi ntɛmntɛm, wɔ adapɛn kakraa bi mu, anaasɛ nkakrankakra wɔ asram anaa mfe pii mu. Ɛtaa fi ase wɔ mmofraase anaa mmerantebere ne mmabaabere mu, nanso ebetumi aba wɔ mfe biara mu. Nneɛma pii wɔ hɔ a ebetumi de AGL aba.
• Acquired Partial Lipodystrophy (APL): Wɔsan frɛ no Barraquer-Simons syndrome , na saa tebea yi ma srade a ɛwɔ anim, kɔn, abasa, ne moma so no so tew nkakrankakra wɔ mmofraase. Nnipa binom nso betumi anya srade a ɛboro so wɔ mmeae te sɛ yafunu, nan, ne akyi. APL is often associated with autoimmune conditions .
• Highly active antiretroviral therapy (HAART)-induced lipodystrophy (LD-HIV): Saa lipodystrophy yi ba nnipa a wɔanya human immunodeficiency virus (HIV) bere a wɔanya nnuru a ekum ɔyare mmoawa a ɛyɛ adwuma kɛse (HAART) a HIV-1 protease inhibitors ka ho akyi Sɛnea tebea yi ba no gyina sɛnea ayaresa no mu yɛ den ne bere tenten a wɔde yɛ no so. Nnipa a wɔwɔ LD-HIV taa nya srade a ɛyera nkakrankakra fi wɔn nsa, wɔn nan, ne wɔn anim. Nnipa binom nso betumi anya srade a ɛboro so wɔ wɔn anim, wɔn kɔn, wɔn akyi atifi, ne wɔn asen mu.
• Localized Lipodystrophy: Eyi ne bere a srade yera wɔ nipadua no fã ketewaa bi pɛ. Sɛ nhwɛso no, tebea yi betumi aba bere a wɔde nnuru (te sɛ insulin) gu baabi koro no ara mpɛn pii no. Ɛte sɛ abon ketewaa bi, nanso mpɛn pii no, ɛnka honam ani hwɛbea a ɛkata so no.

So Lipodystrophy ne Lipoatrophy yɛ ade koro?

Lipodystrophy yɛ asɛmfua a wɔde gyina hɔ ma srade a wɔkyekyɛ wɔ ɔkwan a ɛnteɛ so. Ɛne Lipoatrophy , a ɛkyerɛ sɛ srade a wɔhwere no nso wɔ abusuabɔ. Nyansahufo ne nnuruyɛfo binom de nsɛmfua abien no nyinaa di dwuma de kyerɛkyerɛ tebea koro no ara mu. Sɛ yɛbɛka no tiawa a, Lipoatrophy yɛ Lipodystrophy no fã ketewaa bi.

Henanom na tebea yi ka no kɛse? Ɛtaa ba dɛn?

Lipodystrophy ahorow dodow no ara fi ase wɔ mmofraase, nanso ahorow a wonya no nso betumi anya nkɔso wɔ mpanyimfo mu.

Sɛ HAART-induced lipodystrophy (LD-HIV) , nkutoo nka ho a, srade mu srade ahorow afoforo a wonya no taa ka mmea. Esiane sɛ HIV yareɛ no abu so wɔ mmarima mu nti, LD-HIV nso abu so wɔ mmarima mu.

Mpɛn pii no, lipodystrophy ho yɛ na koraa . Nanso, lipodystrophy ahorow a wonya (nkwa nna nyinaa) no reyɛ nea abu so esiane nnuru bi mu nsunsuanso bɔne nti.

Ɔkwan bɛn so na lipodystrophy ka me nipadua?

Ɛsono sɛnea lipodystrophy biara ka nipadua no, nanso nneɛma atitiriw abien na ɛtaa ba: srade a ɛyera ne hormone leptin a enni hɔ.

Nkɛntɛnso a srade a wɔhwere nya wɔ nipadua no so

Nkwammoaa a wɔfrɛ no adipocytes na ɛyɛ yɛn srade ntini no . Adipocyte nkwammoaa biara kura bɛyɛ 90% lipid droplets. Saa srade nkwammoaa yi sie srade (triglycerides). Sɛ srade nkwammoaa yi sɛe esiane lipodystrophy nti a, wontumi nkora srade so yiye.

Wɔ Lipodystrophy tebea horow bi mu no, srade a ayera yi kɔ yɛn nipadua no ntini afoforo mu wɔ ɔkwan a ɛnteɛ so, sɛ nhwɛso no, mmerɛbo, dwensɔtwaa, anaa ntini mu ntini mu. Eyi betumi de akwahosan ho haw ahorow te sɛ:

• Srade mmerɛbo mu yare / mmerɛbo mu steatosis
• Insulin a ɛko tia ne insulin dodow a ɛkɔ soro wɔ mogya mu (hyperinsulinemia) .
• Asikreyare (Asikreyare) .
• Triglycerides dodow a ɛkɔ soro wɔ mogya mu (hypertriglyceridemia) .
• Pancreatitis a ɛyɛ yare
• Nkwammoaa mu nkwaadɔm mu yare
• Coronary ntini mu yare

Nanso kae sɛ ɛnyɛ obiara a ɔwɔ lipodystrophy na obenya saa tebea horow yi. Ebia ebinom wɔ tebea a emu nyɛ den, bere a afoforo nso betumi anya nea emu yɛ den kɛse.

Nkɛntɛnso a Leptin a Wonnya No Nya wɔ Nipadua no So

Bere a nnipa a wɔwɔ srade mu srade hwere srade no, wɔhwere nkwaadɔm bi nso, titiriw hormone leptin .

Leptin yɛ hormone a yɛn srade ntini na ɛyɛ. Ɛboa ma yɛma yɛn nipadua mu duru yɛ nea ɛfata bere tenten. Wunim ɔkwan a wɔfa so yɛ saa? Ɛdenam ma yɛte nka sɛ yɛayɛ ma na yɛadi yɛn kɔm so. Nyansahufo da so ara reyɛ nhwehwɛmu wɔ leptin ho. Wogye di sɛ leptin ka yɛn nipadua mu nneɛma a ɛsakra , endocrine system dwumadi, ne nipadua no mu tumi a ɛko tia nyarewa no dwumadi.

Ebia nnipa a wɔwɔ lipodystrophy no behu sɛ leptin dodow so atew, na ebetumi ama ɔkɔm de wɔn dodo, insulin a wɔko tia, ne akwahosan ho haw afoforo.

Dɛn ne lipodystrophy ho sɛnkyerɛnne ahorow?

Esiane sɛ lipodystrophy ahorow pii wɔ hɔ nti, sɛnkyerɛnne ahorow no nso gu ahorow yiye.

Nsɛnkyerɛnne a ɛtaa ba ne srade a ɛyera pefee na ɛkɔ so wɔ nipadua no mmeae bi, bere a bere koro no ara mu no, srade a ɛboaboa ano wɔ nipadua no mmeae afoforo wɔ ɔkwan a ɛnteɛ so anaasɛ wɔmpɛ.

For example, people with acquired partial lipodystrophy (APL) gradually lose fat in their face, neck, arms, and chest during childhood. Ebia nnipa binom a wɔwɔ APL nso benya srade a ɛboro so wɔ mmeae te sɛ yafunu, wɔn nan, ne wɔn akyi.

Ebia worenhu akwahosan ho haw titiriw biara mfe pii a, egyina srade a ɛyɛ mmerɛw a wowɔ ne mfe a woadi so. Nanso, lipodystrophy ahorow pii ma mogya mu srade, triglycerides, ne asikre (glucose) dodow kɔ soro. Wo duruyɛfo betumi de mogya mu nhwehwɛmu a wɔyɛ no daa te sɛ lipid panel ne basic metabolic panel ahu eyinom .

Lipodystrophy ahorow bi, titiriw lipodystrophy fã bi, betumi ayɛ den sɛ wobehu. Enti, ɛho hia sɛ wokɔ oduruyɛfo nkyɛn sɛ wo anaa wo ba nya yare no ho sɛnkyerɛnne foforo anaasɛ sɛ sɛnkyerɛnne bi a ɛwɔ hɔ dedaw no mu yɛ den a, ɛmfa ho nea ɛde ba.

Dɛn na ɛde lipodystrophy ba?

Nea ɛde lipodystrophy ba no gu ahorow gyina sɛ ebia efi awosu mu anaasɛ wonyae so.

Nneɛma a Ɛde Awosu mu Lipodystrophy Ba

Awosu mu srade a ɛma mogya tu – a ɛne awosu mu srade a ɛkɔ nipadua no mu nyinaa (CGL) ne abusua mu srade a ɛyɛ fã bi (FPLD) – fi awosu mu nsakrae ahorow bi mu .

Awosu mu nsakrae yɛ nsakrae a ɛba yɛn DNA nhyehyɛe mu. Yɛn DNA nnidiso nnidiso ne nea ɛma yɛn nkwammoaa no nya nsɛm a wohia na ama wɔatumi ayɛ wɔn nnwuma. Enti, sɛ DNA nnidiso nnidiso yi fã bi nni mũ anaasɛ asɛe a, yebetumi anya awosu mu yare bi ho sɛnkyerɛnne.

• Causes of congenital generalized lipodystrophy (CGL): CGL types 1 to 4 are caused by mutations in the genes AGPAT2, BSCL2, CAV1 , and CAVIN1 . Saa awosu mu nkwaadɔm yi ho hia ma nkwammoaa a ɛkora srade (adipocytes) a ɛwɔ yɛn srade ntini mu no nyin na ɛyɛ adwuma. Nsakrae a ɛba saa awosu mu nkwaadɔm yi mu no ka srade nkwammoaa no nhyehyɛe ne ne dwumadi. Abofra a ɔwɔ CGL nya saa awosu mu nkwaadɔm mu nsakrae yi fi wɔn awofo hɔ. Sɛ awofo baanu no nyinaa wɔ awosu mu nkwaadɔm a wɔayɛ no foforo no biako mpo a, mpɛn pii no wonhu yare no ho sɛnkyerɛnne biara.
• Nea Ɛde Abusua mu Lipodystrophy (FPLD) Ba: Nsakrae a ɛba awosu mu nkwaadɔm pii mu no betumi ama FPLD aba. Nea ɛtaa ba ne LMNA.Nsakrae bi a ɛba awosu mu abɔde bi a wɔfrɛ no LMNA mu. LMNA awosu mu abɔde ne awosu mu nkwaadɔm afoforo a ɛka FPLD ho no kyerɛ srade nkwammoaa ma wɔkora srade so na wɔnyɛ protein ahorow a ɛho hia ma srade a wɔkora so. Sɛ nkwaadɔm mu nsakrae bi ba saa awosu mu nkwaadɔm yi mu biara mu a, ɛka srade nkwammoaa no nyin, ne nhyehyɛe, anaa ne dwumadi wɔ ɔkwan a enye so. FPLD dodow no ara fi awo mu wɔ autosomal dominant nhyehyɛe mu . Eyi kyerɛ sɛ awosu mu nkwaadɔm a wɔayɛ no foforo no biako a wobenya wɔ nkwammoaa biara mu no dɔɔso sɛ ɛde yare no bɛba. Ɛtɔ mmere bi a, obi a ɔwɔ FPLD nya nkwaadɔm mu nsakrae no fi wɔn awofo a wɔanya bi no mu biako hɔ. Wɔ tebea afoforo mu no, nkwaadɔm mu nsakrae foforo a ɛba kwa wɔ awosu mu nkwaadɔm no mu na ɛde ba, na sɛ abusua no mu biara nni hɔ a wanya yare no pɛn mpo a, ebetumi aba.

Nneɛma a Ɛde Acquired Lipodystrophy Ba

Lipodystrophy a wonya no betumi afi nnuru, nipadua no mu tumi a ɛko tia nyarewa , anaasɛ nea ɛde ba a ɛyɛ idiopathic . Ɛwom sɛ awosu mu nnyinaso biara nni hɔ tẽẽ a ɛma obi nya srade a ɛma mogya tu de, nanso nhwehwɛmufo binom gye di sɛ ebia nnipa binom wɔ awosu mu su a ɛma wonya srade a ɛma obi nya srade a ɛyɛ mmerɛw.

• Nea Ɛde Acquired Generalized Lipodystrophy (AGL) Ba: AGL betumi aba bere a obi anya ɔyare bi akyi anaasɛ bere a nipadua no mu tumi a ɛko tia nyarewa no anya yare akyi. Nyarewa a wɔakyerɛ sɛ ɛne AGL wɔ abusuabɔ no bi ne:
• Akokɔsrade (Akokɔsrade / varicella) .
• Akisikuru
• Ɔfe a ɛyɛ hu (pertussis) .
• Diphtheria a ɛma obi ho kyere no
• Ahurututu mu yare
• Nnompe mu yare
• Mononucleosis (Nneɛma biako / mono) .

Ɛnyɛ nea ɛyɛ nokware sɛ wubenya AGL esiane sɛ wowɔ saa nyarewa yi ara kwa nti.

Tebea horow a nipadua no tumi ko tia nyarewa a ɛbata AGL ho no bi ne:

• Thyroiditis a nipadua no tumi ko tia nyarewa
• Hepatitis a nipadua no tumi ko tia nyarewa
• Mmofra honam ani yare
• Ntini mu yare a ɛma ntini mu yare
• Sjogren yare a ɛma obi nya ɔyare no
• mogya a ɛtɔ kɔ mogya mu a ɛma nipadua no tumi ko tia nyarewa

Sɛ wowɔ saa nyarewa a ɛko tia nyarewa yi a, wontumi nka sɛ akyinnye biara nni ho sɛ wubenya AGL.

Mpɛn pii no, wontumi nhu nea ɛde AGL ba (idiopathic).

• Nea Ɛde Acquired Partial Lipodystrophy (APL) Ba: Nyansahufo gye di sɛ yɛn nipadua mu tumi a ɛko tia nyarewa no di mfomso sɛe srade nkwammoaa no na ɛde APL ba. Nnipa a wɔwɔ APL bɛboro 80% wɔ Complement 3 wɔ wɔn mogya mu.Protein bi a wɔfrɛ no complement factor no sua. Mpɛn pii no, saa protein yi ka yɛn nipadua mu tumi a ɛko tia nyarewa no ho. Nnipa a wɔwɔ APL taa nya autoantibody a wɔfrɛ no complement 3-nephritic factor wɔ wɔn mogya mu. Autoantibody yɛ protein bi a ɛwɔ nipadua no mu tumi a ɛko tia nyarewa no mu a edi mfomso tow hyɛ ntini a ɛte apɔw so na ɛsɛe no.

• Nea ɛde srade a ɛma mogya tu (LD-HIV) a ɛyɛ adwuma kɛse a wɔde sa yare a ekum ɔyare mmoawa (HAART) ba: Nyansahufo da so ara ntumi nhu nea enti a HAART a nnuru a esiw HIV-1 protease ano wom no ma srade a ɛyɛ mmerɛw ba.

Asɛmpa no ne sɛ nnipa dodow no ara a wofi ase sa HIV ayaresa mprempren no, ɛnsɛ sɛ wɔhaw wɔn ho pii wɔ srade a ɛma mogya tu ho, efisɛ HIV nnuru foforo ma tebea no nyɛ den.

Wobɛyɛ dɛn ahu sɛ wowɔ lipodystrophy?

Sɛ wowɔ lipodystrophy ho sɛnkyerɛnne a, wo duruyɛfo no bɛyɛ wo nipadua mu nhwehwɛmu, abisa w’ayaresa ho abakɔsɛm ne w’abusua aduruyɛ ho abakɔsɛm, na afei ahyɛ sɛ wɔnyɛ nhwehwɛmu bi mfa nkyerɛ sɛ woahu yare no na wahwɛ sɛ ebia nneɛma afoforo bi wɔ hɔ a ɛde wo sɛnkyerɛnne ahorow no ba anaa.

Nhwehwɛmu bɛn na wɔde hu sɛ obi anya srade a ɛma mogya tu?

Ebia wo duruyɛfo bɛhyɛ sɛ wɔnyɛ nhwehwɛmu pii mfa nhu sɛ wowɔ lipodystrophy ne/anaasɛ sɛ ebia nneɛma afoforo bi wɔ hɔ a ɛde wo sɛnkyerɛnne ahorow no ba anaa. Eyinom bi ne:

• Full-body MRI (Magnetic Resonance Imaging) scan: MRI de magnet kɛse, radio asorɔkye, ne kɔmputa yɛ akwaa ne nneɛma afoforo a ɛwɔ wo nipadua mu no ho mfonini kɔ akyiri. Ebia wo duruyɛfo bɛhyɛ nhwehwɛmu yi de ahwɛ sɛnea srade a ɛwɔ wo nipadua mu no te ne sɛnea ɛkyekyɛ.
• Comprehensive Metabolic Panel: Eyi yɛ mogya mu nhwehwɛmu a wɔde susuw nneɛma ahorow 14 a ɛwɔ wo mogya mu. Ɛde nsɛm a ɛho hia ma wɔ wo nipadua mu nnuru a ɛkari pɛ ne sɛnea ɛsakra no ho. Oduruyɛfo no bɛhwɛ asikre (glucose) dodow a ɛwɔ wo mogya mu ne mmerɛbo mu enzymes pɔtee .
• Lipid Panel: Eyi nso yɛ mogya mu nhwehwɛmu. Ɛkyerɛ srade nketenkete a wɔfrɛ no lipids dodow a ɛwɔ wo mogya mu. Mpɛn pii no, nea ɛka sɔhwɛ yi ho ne srade anan a wɔde susuw ne triglyceride susuw. Mpɛn pii no, srade a ɛwɔ nipadua mu no ma mogya mu srade dodow a ɛnteɛ ba.
• Leptin Sɔhwɛ: Eyi kyerɛ sɛnea leptin dodow a ɛwɔ wo mogya mu no te. Sɛ wowɔ lipodystrophy na wo leptin dodow sua sen sɛnea ɛte daa a, eyi betumi ama woanya sɛnea wo nipadua bɛyɛ n’ade wɔ leptin a wɔde besi ananmu ho adwene bi.
• Awosu mu Nhwehwɛmu: Sɛ wo duruyɛfo susuw sɛ wowɔ Lipodystrophy a wonya fi awo mu (awosu mu) a, ebia ɔbɛkamfo akyerɛ sɛ wɔnyɛ awosu mu nhwehwɛmu de si so dua sɛ woahu.
• Asaabo mu nhwehwɛmu:Nea ɛka eyi ho ne oprehyɛn a wɔde yi asaabo mu ntini bi na wɔde afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ mu. Ebia wo duruyɛfo bɛhyɛ nhwehwɛmu yi de ahwɛ sɛ ebia srade a ɛwɔ w’asaabo mu no aka wo anaa.

Dɛn ne ayaresa ahorow a wɔde sa lipodystrophy?

Lipodystrophy ayaresa ne sɛnea wodi ho dwuma no gyina ɔkwan pɔtee a wowɔ so, ne sɛ ebia wowɔ tebea afoforo a ɛbata ho, te sɛ asikreyare anaa srade dodow a ɛnteɛ.

Ayaresa a wɔtaa de di dwuma de di srade a ɛyɛ mmerɛw ho dwuma ne:

• Nnuru a wɔde besi leptin ananmu: Ebia wo duruyɛfo bɛkyerɛw hormone leptin a wɔayɛ a wɔfrɛ no metreleptin . Nnipa a wɔwɔ lipodystrophy taa nya leptin a enni nipadua no mu. Saa hormone yi boa ma nipadua no mu nneɛma a ɛsakra no yɛ adwuma yiye na ebetumi nso atew srade ne triglyceride dodow a ɛkɔ soro no so.
• Asikreyare ne insulin a ɛko tia ayaresa: Sɛ wowɔ insulin a ɛko tia ne/anaasɛ asikreyare esiane srade a ɛma mogya tu nti a, wo duruyɛfo betumi akyerɛw wo nnuru a wɔnom te sɛ pioglitazone, metformin, sulfonylureas , anaa thiazolidinediones de asa. Ebia ɛho behia sɛ nnipa binom a wɔwɔ lipodystrophy nso nom insulin a wɔayɛ de sa wɔn asikreyare. Ebia ɛho behia nso sɛ wode glucometer hwɛ asikre dodow a ɛwɔ wo mogya mu daa wɔ fie .
• Triglyceride ne srade dodow a wɔbɛhyɛ so: Nnuru a wɔnom a yɛadi kan aka ho asɛm a ɛboa ma wɔsa asikreyare no taa boa ma wɔhyɛ srade dodow so. Ebia wo duruyɛfo nso bɛkyerɛw nnuru a wɔfrɛ no statins te sɛ rosuvastatin ne pravastatin . Ebia ɛho behia sɛ nnipa a triglyceride dɔɔso no fa fibric acid a efi mu ba anaa n-3 polyunsaturated fatty acids , te sɛ nea ɛwɔ mpataa ngo mu a wɔde ka ho.
• Oprehyɛn a wɔde siesie wɔn ho ne akwan a wɔfa so yɛ wɔn ho: Ebia nnipa a srade a ɛwɔ mmeae a ɛyɛ fɛ te sɛ anim, koko, ne awotwaa mu no bɛyɛ oprehyɛn a wɔde siesie wɔn ho na ama wɔn ho yɛ fɛ na wɔanya wɔn ho mu ahotoso. Nnuruyɛfo a wɔyɛ oprehyɛn a wɔde yɛ oprehyɛn betumi ayɛ autologous adipose tissue transplantation, wɔde anim a wɔde ayɛ anim a wɔmfa hwee nka ho, ne silicone anaa nneɛma afoforo a wɔde hyɛ nipadua mu. They may also use liposuction or surgical removal techniques to remove unwanted fat deposits in areas such as the chin or back of the neck (often called the "buffalo hump" ).

Nyansahufo da so ara wɔ pii a ɛsɛ sɛ wosua fa sɛnea wɔbɛsa srade a ɛma mogya tu na wɔadi ho dwuma ho. Bere a wohu sɛnea nipadua no mu nneɛma a ɛsakra no yɛ den no ho nsɛm pii no, ebia ayaresa pii bɛba.

So wobetumi asiw lipodystrophy ano?

Mpɛn pii no, wontumi nsiw Lipodystrophy ano.

Wontumi nsiw awosu mu srade a ɛma mogya tu no ano, efisɛ efi awosu mu nkwaadɔm mu nsakrae a wonya fi awo mu mu. Sɛ woreyɛ nhyehyɛe sɛ wobɛwo mma a, te asiane a ɛwɔ sɛ wobɛwo abofra a ɔwɔ awosu mu yare bi ase na wo ne wo duruyɛfo nkasa mfa awosu mu nhwehwɛmu ho.

Mpɛn pii no, ɔyare mmoawa anaa nipadua no mu tumi a ɛko tia nyarewa na ɛde lipodystrophy a wonya no ba. Bere a wobetumi asiw nyarewa bi te sɛ akokɔsrade ne ɔfe a ɛyɛ hu ano denam nnuru a wɔde bɔ nkurɔfo ho ban so no, wontumi nsiw nyarewa afoforo ne nipadua mu ahoɔden a ɛko tia nyarewa a ɛbata srade a ɛma obi nya srade ho no ano.

Dɛn ne nkɔmhyɛ a ɛfa lipodystrophy ho?

Lipodystrophy ho anidaso gyina lipodystrophy ko a wowɔ so kɛse, ne sɛ ebia wowɔ tebea anaa nsɛnnennen afoforo a ɛbata ho, te sɛ asikreyare, mmerɛbo anaa asaabo mu haw ahorow.

Nneɛma a wɔde yɛ ahosiesie a wɔde teɛteɛ mmeae a srade sua ne mmeae a srade boro so no boa ma nnipa a wɔwɔ lipodystrophy no asetra tu mpɔn.

Sɛ wohu sɛ wo anaa wo ba no anya lipodystrophy a, wo ne wo duruyɛfo nkasa mfa nea wobɛhwɛ kwan ne ɔkwan a wobɛfa so adi tebea no ho dwuma yiye ho.

Bere bɛn na ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn wɔ lipodystrophy ho?

Sɛ wuhu sɛ wo anaa wo ba no nipadua mu srade kɔ so so tew wɔ mmeae pɔtee bi, anaasɛ srade rekɔ soro wɔ mmeae bi a, wo ne wo duruyɛfo nkasa.

Sɛ wo anaa wo ba no nya Lipodystrophy a, ɛsɛ sɛ wo ne w’aduruyɛfo kuw no hyia daa hwɛ sɛ w’ayaresa no reyɛ adwuma yiye ama wo.

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

Lipodystrophy yɛ tebea a ɛntaa nsi nanso emu yɛ den. Bere a wonni aduru biara no, ayaresa ahorow bi betumi aboa ma wɔadi ne sɛnkyerɛnne ne tebea horow a ɛbata ho, te sɛ asikreyare ne srade dodow a ɛnteɛ ho dwuma.

Ɛsono ayaresa a wɔde ma no kɛse wɔ onipa biara mu. Enti, w’aduruyɛ kuw no ne wo bɛyɛ adwuma de ayɛ nhyehyɛe a eye ma wo. Nsuro sɛ wubebisa wo duruyɛfo nsɛm. Wɔwɔ hɔ sɛ wɔbɛboa wo. Akyinnye biara nni ho sɛ saa nimdeɛ yi bɛboa wo ma woanya asetra a ahoɔden wom!

` lipodystrophy, srade ntini, leptin, awosu, a wonya, asikreyare, srade, triglyceride, HIV, nipadua mu nkwaadɔm mu nyarewa