Mmɛn yɛ adwumayɛfo a wɔyɛ komm na wonni adagyew sen biara wɔ yɛn nipadua mu no mu biako. Ɛyɛ adwuma pii a yennim mpo. Efi sɛnea ɛboa ma wɔyam aduan so kosi awuduru a eyi fi nipadua no mu so no, n’asɛyɛde ahorow a wɔahyehyɛ no ware. Enti ɛtɔ da bi a, ɛsɛ sɛ yɛhwɛ sɛ biribi asɛe wɔ mmerɛbo a ɛyɛ adwumaden yi ho, sɛ wabrɛ, na ɛreyɛ n’adwuma yiye anaa. Nea eye ne sɛ, yebetumi ahu eyi ho pii denam mogya mu nhwehwɛmu a ɛnyɛ den so. Ɛnnɛ yɛreka ‘Liver Function Tests’, a obiara nim no sɛ LFTs ho asɛm.
Sɛ yɛbɛka no tiawa a, dɛn ne saa Mmerɛbo Dwumadi Ho Nhwehwɛmu (LFT) yi?
Ɛyɛ mmerɛw yiye. LFT yɛ nhwehwɛmu ahorow a wɔde mogya ketewaa bi a wogye fii ntini bi a ɛwɔ wo basa mu mu di dwuma . Wɔsusuw nneɛma ahorow (te sɛ enzymes ne protein) dodow a wo mmerɛbo yɛ anaasɛ ɛboaboa ano wɔ wo mogya mu bere a wo mmerɛbo asɛe no.
Fa no sɛ wode wo kar no bɛkɔ akɔyɛ adwuma. Mfiridwumayɛfo no susuw nneɛma te sɛ engine mu ngo ne coolant na ama wanya adwene wɔ engine no tebea ho, ɛnte saa? Saa ara nso na oduruyɛfo hwɛ nneɛma yi dodow a ɛwɔ wo mogya mu na ama wanya wo mmerɛbo no akwahosan ne sɛnea ɛyɛ adwuma ho adwene a ɛho hia.
Dɛn nti na oduruyɛfo bi bɛka akyerɛ wo sɛ yɛ saa LFT yi?
Ebia nneɛma pii nti na wo duruyɛfo betumi akamfo nhwehwɛmu yi akyerɛ.
- Hwɛ sɛ wususuw sɛ wowɔ mmerɛbo mu yare: Sɛ wowɔ sɛnkyerɛnne ahorow a ɛte sɛ jaundice, w’ani yɛ kɔkɔɔ, ɛyaw wɔ wo yafunu nifa so, anaasɛ wote nka sɛ wo ho ayɛ wo hyew a, ebia wɔbɛka akyerɛ wo sɛ yɛ nhwehwɛmu yi efisɛ wususuw sɛ hepatitis anaa yare foforo bi.
- Hwɛ mmerɛbo mu yare a ɛwɔ hɔ dedaw no so: Sɛ wowɔ mmerɛbo mu yare dedaw (sɛ nhwɛso no, akisikuru) a, wɔyɛ nhwehwɛmu yi daa de hwɛ sɛnea ɛrekɔ so, sɛ ebia yare no mu reyɛ den, anaasɛ wobetumi adi so.
- Hwɛ sɛ ayaresa no yɛ yiye anaa: Saa sɔhwɛ yi nso boa ma wohu sɛ ebia nnuru a wɔde ma mmerɛbo mu yare no reyɛ adwuma anaa, na sɛ yare no renya nkɔso anaa.
- Hwɛ nsunsuanso bɔne a nnuru a wonom no de ba: Nnuru bi te sɛ nnuru a ɛma mogya mu srade so tew ne nnuru a wɔde kum ɛyaw bere tenten betumi aka mmerɛbo no. Enti, sɛ wode nnuru a ɛtete saa di dwuma a, nnuruyɛfo nso yɛ saa LFT yi de hwɛ sɛ ebia nkɛntɛnso bi wɔ mmerɛbo no so anaa.
Nneɛma titiriw bɛn na wɔhwɛ wɔ LFT mu?
Sɛ wohwɛ LFT amanneɛbɔ bi a, wobɛhunu Borɔfo nkyerɛwdeɛ ne nɔma ahodoɔ bi. Sɛ wohwɛ a, ebia ɛbɛyɛ te sɛ nea ɛyɛ den kakra, nanso akontaahyɛde yi mu biara ka mmerɛbo dwumadi afã horow ho asɛm kyerɛ wo. Momma yɛnhwɛ nea nneɛma atitiriw yi yɛ.
| Sɔhwɛ Edin | Dɛn na eyi kyerɛ? |
|---|---|
| Mmerɛbo mu Enzymes ALT, AST, ALP, GGT, ne wɔn a wɔka wɔn ho no | Eyinom ne nea wonim no yiye sen biara. Sɛ mmerɛbo mu nkwammoaa sɛe, epirapira, anaa ɛyɛ hyew a, saa enzymes yi fi mogya no mu. Enti sɛ wɔn dodow kɔ soro wɔ mogya no mu a, ɛkyerɛ sɛ mmerɛbo no wɔ adwennwen bi mu. |
| Protein ne Albumin nyinaa | Mmɛn na ɛma protein a yɛn nipadua hia no pii. Albumin yɛ protein atitiriw a ɛte saa no mu biako. Sɛ mmerɛbo no ntumi nyɛ adwuma yiye a, protein yi a wɔyɛ no so tew. Eyi betumi ama protein dodow a ɛwɔ mogya no mu no so atew. |
| Bilirubin a wɔde di dwuma | Eyi yɛ nwura kɔkɔɔ a ɛba bere a mogya mu nkwammoaa kɔkɔɔ asɛe no. Mmɛn a ɛwɔ apɔwmuden no fa saa bilirubin yi, de ka bile ho, na eyi fi nipadua no mu. Sɛ mmerɛbo no nya ɔhaw bi a, saa dwumadi yi ntumi nyɛ adwuma yiye. Afei bilirubin boaboa ano wɔ mogya no mu, na ɛma aniwa ne honam ani yɛ kɔkɔɔ. Yɛsan frɛ eyi sɛ ‘atiridii kɔkɔɔ’. |
| Prothrombin Bere (PT) . | Mmɛn no nso yɛ protein soronko (clotting factors) a ɛboa ma mogya tu. PT nhwehwɛmu no kyerɛ bere tenten a egye ansa na wo mogya no ayɛ mmerɛw. Sɛ mmerɛbo no sɛe a, protein ahorow yi a wɔyɛ no so tew. Eyi ma bere a egye ansa na mogya atɔ no yɛ kɛse. |
So mogya mu nhwehwɛmu yi yɛ den sɛ wɔbɛyɛ?
Nte saa koraa. Eyi yɛ mmerɛw yiye na wobetumi ayɛ wɔ simma kakraa bi mu.
Sɛ wokɔ ayaresabea anaa lab a, ɔyarehwɛfo anaa mfiridwumayɛfo bi behu ntini bi wɔ wo basa mu a ɛbɛn wo nsateaa na wasiesie beae no. Afei, wɔde ade ketewaa bi bedi dwuma de aboaboa mogya kakraa bi ano agu toa mu. Ebia wobɛte nka sɛ wo ho yɛ wo yaw kakra, nanso ebefi hɔ ntɛm. Sɛ wɔtwe mogya no wie a, wɔde nhwɛsode no kɔ aduruyɛdan bi mu. Ebia ebegye nnɔnhwerew kakraa bi anaa da koro anaa abien ansa na nea efi mu ba no asan aba.
Ade a ɛho hia sen biara ne sɛ wubebisa wo duruyɛfo sɛ ebia ɛsɛ sɛ wudi mmuada ansa na wɔayɛ nhwehwɛmu yi anaa. Ɛtɔ da bi a, ebia wɔbɛka akyerɛ wo sɛ di mmuada efisɛ wɔyɛ no ka sɔhwɛ afoforo ho.
Ɔkwan bɛn so na yɛbɛte gyinapɛn ahorow a ɛwɔ amanneɛbɔ no mu ase? (Normal Ranges) .
Sɛ wo nsa ka w’amanneɛbɔ a, wobɛhunu wo nkontabuo wɔ sɔhwɛ biara mu, ne ‘Normal Range’. Nanso ade biako wɔ hɔ a ɛho hia paa a ɛsɛ sɛ yɛkae wɔ ha.
Mma wo ho nnpopo anaasɛ nsi gyinae sɛ wowɔ yare bi bere a wuhu gyinapɛn ahorow a ɛwɔ amanneɛbɔ yi mu no. Wo duruyɛfo nkutoo na obetumi ate eyi ase pɛpɛɛpɛ na wayɛ nea ɛfata wo tebea no.
Efisɛ sɛnea gyinapɛn ahorow a ɛfata no betumi ayɛ soronko kakra wɔ lab biara mu. Saa gyinapɛn ahorow yi nso betumi ayɛ soronko a egyina nneɛma te sɛ mfe a obi adi ne ɔbarima anaa ɔbea so.
Botae ahorow bi a wɔtaa de di dwuma ni:
| Sɔhwɛ | Normal Range a Ɛyɛ Fɛ |
|---|---|
| Alanine transaminase (ALT) a wɔde di dwuma wɔ ɔkwan a ɛyɛ hu so. | 0 kosi 45 IU/L |
| Aspartate transaminase (AST) a wɔde hyɛ nipadua mu no . | 0 kosi 35 IU/L |
| Alkaline phosphatase (ALP) a wɔde yɛ aduru a wɔfrɛ no phosphatase (ALP) . | 30 kosi 120 IU/L |
| Bilirubin a wɔde di dwuma | 2 kosi 17 micromoles/L |
| Prothrombin bere (PT) . | 10.9 kosi 12.5 sikɔne |
| Albumin a wɔde yɛ adwuma | 40 kosi 60 g/L |
Dɛn na ALT ne AST dodow a ɛkɔ soro no kyerɛ?
Adeɛ a ɛdi kan a nnipa dodoɔ no ara de wɔn adwene si so wɔ LFT amanneɛbɔ mu ne enzyme dodoɔ mmienu, ALT ne AST. Sɛ eyinom kɔ soro a, ɛkyerɛ sɛ mmerɛbo mu nkwammoaa no asɛe kakra.
Nanso, nnuruyɛfo nso hwɛ sɛnea saa gyinapɛn abien yi yɛ pɛ. Sɛ nhwɛso no, sɛ AST dodow no boro ALT dodow no so bɛyɛ mmɔho abien a, ɛtaa kyerɛ sɛ mmerɛbo no asɛe esiane nsa a wɔnom nti. Sɛ gyinapɛn abien no nyinaa bɛyɛ pɛ a, ebetumi aba sɛ efi biribi foforo a ɛde ba (sɛ nhwɛso no, ɔyare mmoawa bi).
Nyarewa bɛn na LFT kyerɛ?
Eyi yɛ biribi a ɛsɛ sɛ yɛte ase. LFT sɔhwɛ no yɛ anammɔn a edi kan ara kwa wɔ akwantu a wɔde hwehwɛ yare no mu. Ɛte sɛ nsɛnkyerɛnne a edi kan a ɔsraani a ɔhwehwɛ nkurɔfo ho nsɛm mu nya. Nea afi sɔhwɛ yi mu aba nkutoo ntumi nsi yare bi so dua koraa. Nanso, ɛma oduruyɛfo no nya akwankyerɛ pa wɔ baabi a ɔhaw no da ne nea ɛsɛ sɛ ɔyɛ akyi.
Sɛ nea efi LFT mu ba no nyɛ nea ɛfata a, ebia ɛho behia sɛ wɔyɛ nhwehwɛmu foforo te sɛ ultrasound scan, mogya mu nhwehwɛmu titiriw afoforo, ne ebia mmerɛbo mu nhwehwɛmu.
Tebea horow a LFT sɔhwɛ ahorow betumi akyerɛ no bi ne:
- Srade Mmerɛbo Yare
- Mmerɛbo a ɛsɛe esiane awuduru nti (Toxic Hepatitis) .
- Mmerɛbo mu yare a ɔyare mmoawa (Viral Hepatitis A, B, anaa C) .
- Nipadua no ankasa nipadua mu ahoɔden a ɛko tia nyarewa no tow hyɛ mmerɛbo no so (Autoimmune Hepatitis) .
- Cirrhosis - akisikuru ne mmerɛbo no a ɛtwetwe
- Bile duct ho haw ahorow
- Mmɛn mu Kokoram
- Nyarewa a wonya fi awo mu te sɛ hemochromatosis
Nkrasɛm a Wɔde Kɔ Fie
- Liver Function Test (LFT) yɛ mogya mu nhwehwɛmu a ɛnyɛ den yiye na ahobammɔ wom a ɛma wunya nsɛm pii fa wo mmerɛbo akwahosan ho.
- Sɛ wo nsa ka sɔhwɛ yi mu aba wie a, nhuruw nkɔ nsɛm a egyina nsɛm a ɛwɔ intanɛt so so. Ɛno bɛma wɔanya ehu a ɛho nhia ara kwa.
- Wo duruyɛfo nkutoo na obetumi ama wo nkyerɛase a edi mu denam gyinapɛn ahorow a ɛwɔ w’amanneɛbɔ no mu a ɔde bɛtoto wo yare no ho sɛnkyerɛnne ne aduruyɛ ho nsɛm afoforo ho no so.
- Ɛnyɛ bere biara a wɔbɛma LFT gyinapɛn ahorow akɔ soro no, ɛkyerɛ sɛ yare a emu yɛ den bi wɔ hɔ. Ɛtɔ da bi a, ebetumi ayɛ ade ketewaa bi a ɛde ba, te sɛ aduru bi a worenom anaa bere tiaa mu ɔyare mmoawa. Nanso ɛho hia sɛ yɛhwehwɛ mu.
- Mmɛn yɛ akwaa a ɛsom bo a ɛyɛ adwuma komm. Enti, sɛ oduruyɛfo kamfo kyerɛ a, ɛho hia yiye sɛ wobɛyɛ nhwehwɛmu a ɛte sɛɛ de ahwɛ sɛnea mmerɛbo no te.
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