Sɛ wo anaa w’abusua mu obi fi ase sa kokoram a, ɛyɛ ade a ɛfata sɛ wobɛte ehu kakra nka na wopɛ sɛ wuhu nnuru a wo duruyɛfo akyerɛw ama wo no. Ɛho hia sɛ wonya nsɛm a edi mũ bere a worefi aduru foforo ase no. Enti ɛnnɛ yɛbɛka aduru pɔtee bi a ɛte saa a ɛko tia kokoram, Lorlatinib ho asɛm. Momma yɛnka ho asɛm tiawa, te sɛ nea yɛn adamfo bi rekyerɛkyerɛ mu akyerɛ wo.
Dɛn ne Lorlatinib?
Sɛ yɛbɛka no tiawa a, lorlatinib nyɛ nnuru a wɔde sa yare a wɔtaa de sa yare. Ɛyɛ adwuma sɛ "ayaresa a wɔde asi wɔn ani so." Eyi kyerɛ sɛ ɛde n’ani si protein pɔtee bi a ɛboa ma kokoram nkwammoaa nyin so tẽẽ. Ɛdenam saayɛ so ma kokoram nkwammoaa no nnyin.
Wɔtaa de sa tebea bi a wɔfrɛ no "ahurututu mu kokoram a ɛnyɛ nkwammoaa nketenkete." Ebia wo duruyɛfo nso bɛkyerɛw saa aduru yi ama tebea afoforo. Sɛ wowɔ nsɛmmisa bi fa ho a, bisa wo duruyɛfo.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru
Ansa na wo duruyɛfo bɛkyerɛw saa aduru yi ama wo no, ɛho hia sɛ wuhu aduruyɛ mu tebea foforo biara a ebia wowɔ no yiye. Ebia saa aduru yi ne saa tebea horow no bedi nkitaho. Enti, sɛ wowɔ tebea horow a edidi so yi mu biara a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo.
- Asikreyare (asikre a ɛwɔ mogya mu) .
- Mogya mmoroso
- Cholesterol a ɛdɔɔso
- Koma mu nnyigyei a ɛnkɔ so pɛpɛɛpɛ anaa komayare
- Asaabo mu yare
- Ahurututu mu yare anaa ahurututu mu akuru
- Adwene mu yare biara
- Tebea horow te sɛ akisikuru
- Adwene a ɛne sɛ wobɛpira wo ho, adwene a ɛne sɛ wubekum wo ho, woabɔ mmɔden sɛ wobɛyɛ saa, anaasɛ wobɛma w’abusua muni bi ayɛ saa
- Mmɔden a wɔbɔ sɛ wobenyinsɛn anaasɛ mprempren wɔrenyinsɛn
- Akokoaa a wɔma no nufu
- Wɔadi kan anya lorlatinib anaa aduru foforo biara, aduan, anaa ade a wɔde yɛ nneɛma a ɛma obi ho yɛ no hyew
Ɔkwan bɛn so ankasa na wode saa aduru yi di dwuma?
Akwankyerɛ pɔtee a wɔde bedi dwuma wɔ aduru yi a wɔde bedi dwuma ho no ho hia yiye ma nea efi mu ba.
- Nom saa aduru yi sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, bere koro no ara mu da biara .
- Mma nntwitwiw, nbubu, anaa nwe tablet no. Fa nsu mene no nyinaa.
- Wubetumi anom ansa na woadi anaa bere a woadi awie, nanso sɛ wo yafunu mu yɛ wo yaw a, ɛbɛyɛ papa sɛ wode ka aduan ho.
- Kɔ so de saa aduru yi di dwuma kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.
- Nea ɛho hia paa:Kwati sɛ wobɛnom bobe nsu koraa bere a worenom aduru yi no.
Na sɛ dodow a wɔde ma no dɔɔso dodo nso ɛ? (Nnuru a wɔde ma boro so) .
Sɛ wususuw sɛ woanom nnuru pii a, kɔ Emergency Department (ETU) a ɛbɛn wo ntɛm ara . Anaasɛ frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ no na woanya afotu.
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wo werɛ fi sɛ wobɛnom dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ennu nnɔnhwerew 4 kosi sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so. Fa dodow a edi hɔ no ara wɔ bere a wɔahyɛ da ayɛ no mu. Mfa nnuru a wɔde di dwuma mmɔho abien da .
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Lorlatinib yɛ aduru a ɛwɔ tumi kɛse sɛ ɛne nnuru afoforo di nkitaho. Enti, ɛsɛ sɛ woka nnuru a wonom nyinaa (a vitamin, nhabannuru, ne nhabannuru tii ka ho) kyerɛ wo duruyɛfo. Ebia ɛne nnuru a edidi so yi bedi nkitaho:
| Mfa eyinom nka lorlatinib ho da. | |
|---|---|
| apalutamide, enzalutamide, mitotane, ranolazine a wɔde yɛ aduru | Nnuru a wɔde ma kokoram ne komayare ahorow |
| Nnuru a ekum akisikuru te sɛ carbamazepine, phenytoin, phenobarbital | Nnuru a wɔde sa akisikuru |
| rifampin, rifapentine, a woagye atom | Nnuru a ekum ɔyare mmoawa a wɔde sa ɔyare mmoawa te sɛ nsamanwaw |
| Ɔhotefo Yohane Wort | Nnuru a wɔde ma a wɔde sa adwenemhaw |
| lumacaftor a wɔde hyɛ nipadua mu; ivacaftor a wɔde di dwuma | Nnuru a Wɔde Sa Cystic Fibrosis |
| Ebia wo ne weinom bɛyɛ w’ade - bisa wo duruyɛfoɔ. | |
| Nnuru a ekum ɔyare mmoawa | Sɛ nhwɛso no: clarithromycin |
| Nnuru a ɛko tia fungal | Sɛ nhwɛso no: ketoconazole, itraconazole, fluconazole |
| HIV ne mmerɛbo mu yare nnuru | Sɛ nhwɛso no: ritonavir, boceprevir |
| Hormone ne awo ano aduru | Nneɛma te sɛ awo ano aduru, aduru a wɔde hyɛ nipadua mu, nnuru a wɔde twitwiw nipadua mu, ne nea ɛkeka ho. |
| Nnuru afoforo | bosentan, modafinil, aduru a wɔde hyɛ nipadua mu |
Nneɛma a ɛsɛ sɛ ɛtra w’adwenem bere a worenom nnuru no
Ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo ho nyɛ wo dɛ kakra bere a wɔreyɛ kokoram ayaresa no, efisɛ ɛka kokoram nkwammoaa ne nkwammoaa a wɔwɔ apɔwmuden nyinaa. Nanso nnyae ayaresa no kosi sɛ wo duruyɛfo bɛka akyerɛ wo. Ka nneɛma bɔne biara a ɛbɛba wo duruyɛfo amanneɛ.
Nyinsɛn, nufu a wɔde ma ne mmarima afotu
Saa ɔfa yi ho hia paa. Yɛsrɛ sɛ monhwɛ yiye.
- Wɔ mmea fam no: Kwati sɛ wubenyinsɛn koraa bere a worenom aduru yi no. Afei nso, kwati sɛ wubenyinsɛn asram 6 bere a woagyae aduru no akyi . Fa ɔkwan a ɛnyɛ hormone a wɔfa so siw awo ano di dwuma (e.g., kɔndɔm, kɔbere T). Sɛ wowɔ adwenem naayɛ bi sɛ woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Kwati sɛ wobɛma nufu bere a worenom aduru no ne nnafua 7 bere a woagyae aduru no akyi.
- Wɔ mmarima fam no:Ɛsɛ sɛ mmarima a wɔnom saa aduru yi de kɔndɔm di dwuma bere a wɔne ɔbea a obetumi anyinsɛn reda no. Ɛsɛ sɛ wɔtoa saa kwan a wɔfa so siw nyinsɛn ano yi so asram 3 bere a wɔagyae aduru no akyi . Sɛ wususuw sɛ wo hokafo no anyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara.
Nyarewa ne atiridiinini
Saa aduru yi betumi ama wo nipadua no tumi a ɛko tia nyarewa no so atew na ama asiane a ɛwɔ hɔ sɛ wubenya nyarewa no ayɛ kɛse. Enti, sɛ wuhu yare no ho sɛnkyerɛnne te sɛ atiridiinini, atiridiinini, menewa mu yaw, anaa ɔfe a, nnyɛ wo ho aduru na frɛ wo duruyɛfo ntɛm ara ma ɔmfa afotu mma wo. Bɔ mmɔden sɛ wobɛtwe wo ho afi ayarefo ho.
Cholesterol ne asikre dodow a ɛwɔ nipadua no mu
Lorlatinib betumi ama mogya mu srade (titiriw triglycerides) ne asikre dodow a ɛwɔ mogya mu no akɔ soro. Ebetumi nso atew srade pa (HDL) so. Wo duruyɛfo bɛhwɛ eyinom daa. Sɛ ɛho hia a, ebia wɔbɛkamfo akyerɛ sɛ wɔnsakra wɔn aduan anaa nnuru foforo.
Nsakrae a ɛba adwenemyare mu
Saa aduru yi betumi aka nnipa binom adwene mu. Sɛ wo anaa w’abusua muni hu nsakrae a edidi so yi bi a, ka kyerɛ wo duruyɛfo ntɛm ara:
- Adwenemhaw foforo anaa nea ɛreyɛ kɛse
- Adwene a ɛne sɛ wobɛpira wo ho
- Brɛ
- Nkae a ɛyera
- Suban anaa nsusuwii ahorow a ɛyɛ soronko, a ɛhaw adwene
Nneɛma bɔne bɛn na wobetumi ahu?
Te sɛ aduru biara no, lorlatinib betumi anya nkɛntɛnso bɔne. Eyinom bi betumi ayɛ aniberesɛm na ɛsɛ sɛ wɔbɔ ho amanneɛ ntɛm ara.
| Nsunsuanso bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara | |
|---|---|
| Nneɛma a ɛma obi ho yɛ no hyew | Honam ani akisikuru, ɛyaw, anim, ano, anaa tɛkrɛma a ɛho ahonhon |
| Koko mu yaw anaasɛ ɛyɛ den | Ebetumi ayɛ komayare ho sɛnkyerɛnne |
| Ɔfe, ahome a ɛyɛ den, nipadua a ɛho ahonhon (edema) . | Mu duru a ɛkɔ soro mpofirim, nansoaa, nsa ne anan a ɛho ahonhon |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo asɛe | Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum, aniwa/honam ani yɛ kɔkɔɔ, ɛyaw wɔ yafunu no atifi nifa so |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare mmoawa | Atiridiinini, awɔw, menewam a ɛyɛ yaw |
| Mogya mu nkwammoaa dodow a ɛba fam ho sɛnkyerɛnne | Ɔhome a ɛyɛ den, ɔbrɛ a ɛtra so, adwenemhaw, ti a ɛyɛ hare |
| Adwene mu nsakrae anaasɛ akisikuru | Atifi hɔ adwene mu sɛnkyerɛnne ahorow, adwene mu naayɛ, akisikuru |
| Sɛ ɛkɔ so anaasɛ ɛhaw wo a, ka kyerɛ wo duruyɛfo. | |
| Akisikuru, ɔfe | Mogya mmoroso a ɛkɔ soro |
| Anisoadehu sesa, anisoadehu a ɛyɛ kusuu | Cholesterol dodow a ɛkɔ soro |
| Dae a wontumi nna anaasɛ nna a ɛso tew | Nkae a ɛyera, abufuw |
Nkrasɛm a Wɔde Kɔ Fie
- Fa aduru no sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, wɔ bere a ɛfata mu, ne dodow a ɛfata mu. Mmu anaasɛ nbubu aduru no da.
- Ka nnuru afoforo, vitamin, ne nhabannuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo. Titiriw kwati sɛ wobɛnom bobe aba mu nsu.
- Kwati sɛ wubenyinsɛn bere a worenom aduru yi ne bere tenten a wo duruyɛfo kamfo kyerɛ no. Ɛsɛ sɛ mmea ne mmarima nyinaa hu eyi.
- Sɛ wunya ɔhaw biara a emu yɛ den te sɛ ahome a ɛyɛ den, wo koko mu yaw, wo ho wosow kɛse, anaasɛ nsakrae kɛse bi ba wo adwene mu a, hwehwɛ aduruyɛfo afotu ntɛm ara.
- Saa aduru yi yɛ wo nkutoo dea. Mfa biribiara nnkyɛ nkyerɛ afoforo.
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