Sometimes we develop various diseases related to the lungs . Among them, one that is not often heard of, but is important, is lung disease caused by a deficiency of the enzyme alpha-1 antitrypsin. This is a genetic condition. So today we are talking about a special treatment for this condition. Let us simply talk about everything you need to know about this treatment.
What is this Alpha-1-proteinase Inhibitor?
Simply put, this is a treatment that restores an important enzyme that is lacking in your body. Our body has an enzyme called Alpha-1 Antitrypsin (ATA) that protects our lungs. Some people have very low levels of this enzyme in their bodies. This can easily damage their lungs.
Imagine that your body has lost this important enzyme that protects your lungs. What this `Alpha-1-proteinase Inhibitor` vaccine does is to restore that lost enzyme to your body. It's like putting some oil in a car that's low.
But one thing must be kept in mind. This is not a cure for the disease. But it does help to control further damage to the lungs caused by the disease. We call this replacement therapy.
Things to tell your doctor before using this medicine
Before you begin this treatment, it is very important to give your doctor a complete description of your health condition. In particular, you should definitely tell him about the following things.
- If you have a condition called IgA deficiency (Immunoglobulin A deficiency) .
- If you have allergies to this medicine called `Alpha-1-proteinase Inhibitor` or any other medicine, food, or dye.
- If you are pregnant or trying to get pregnant .
- If you are a breastfeeding mother .
Based on this information, your doctor will be able to decide whether this treatment is right for you or not.
How do you use this medicine?
This medicine is given as an infusion into a vein. This is usually given once a week.
Initially, this vaccine is given in a hospital or clinic. However, sometimes, after you have received the necessary training, your doctor may allow you to receive this vaccine at home. In this case, you should follow the instructions given by the doctor or nursing staff exactly. Do not use more than the prescribed dose.
What do you do with used needles?
This is very important. It is not a good idea to throw used needles and syringes in the trash. They should be put in a special sharps container. If you don't have one, ask your doctor for one.
What if I take too much medicine?
If you think you have overdosed on this medicine, do not panic. Immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the ETU (Emergency Treatment Unit) of the nearest hospital.
What do you do if you miss a medication appointment?
This is a treatment that is usually given once a week, so it is very important to take it on time. If you miss a dose, don't panic and call your doctor for advice. If you are taking your medication at home, take it as soon as you remember and go back to your regular weekly schedule. However, it is best to talk to your doctor about this as well.
Things to be careful about when taking medicine
Keep an eye on your symptoms while taking this medicine. If your symptoms do not improve or seem to get worse, tell your doctor.
- Allergies: This medication can sometimes cause severe allergic reactions. Therefore, ask your doctor if you need to keep something like an epinephrine pen handy in case of an allergic reaction.
- Risk of infection: Because this medicine is made from human blood plasma, there is a small risk of it containing viruses or bacteria. But don't worry, special methods are used to kill such germs when making these products. If you have any questions about this, feel free to talk to your doctor.
What are the possible side effects?
Like any medication, this one can have some side effects . Let's take a look at what they are.
| Side effect | Description |
|---|---|
| Severe allergies | Skin rash, itching, swelling of the face, lips or tongue. |
| Difficulty breathing | Difficulty breathing, shortness of breath. |
| Chest pain or tightness | Chest tightness, pain. |
| Dizziness or fainting | Dizziness , fainting, falling. |
| Signs of infection | Fever, chills, cough, sore throat. |
| Leg swelling | Swelling of the ankles or legs. |
| Unusual fatigue | Excessive fatigue in the body. |
| Common side effects | Diarrhea, dizziness, headache, feeling hot, joint or muscle pain, nausea, pain or redness at the injection site, runny nose. |
This list does not include all side effects. If you experience anything different, talk to your doctor about it.
How should you store your medicine?
- Do not leave this medicine within the reach of children .
- Store unopened vials in the refrigerator at 2-8 °C. Do not freeze .
- It can be stored at room temperature (below 25 degrees Celsius) for up to a month. However, do not refrigerate it again after it has been stored at room temperature.
- Do not shake the medicine bottle.
- Discard expired medication without using it.
If you have any further questions about this medication, don't hesitate to talk to your doctor and resolve them.
Take-Home Message
- This medicine is a treatment for lung diseases caused by `Alpha-1 Antitrypsin` deficiency, but it is not a medicine that completely cures the disease.
- Before using the medicine, tell your doctor about all your medical conditions and allergies.
- If you experience severe allergic symptoms ( difficulty breathing , swelling , chest pain ), seek medical advice immediately.
- Dispose of used needles safely in a sharps container only.
- If you miss a dose or take too much, call your doctor immediately.
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