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Did the doctor prescribe Amitriptyline pills for you too? Let's learn more about this medicine (Amitriptyline)

MBBS
Medically Reviewed by MBBS ✓ Medically Reviewed
📅 Updated: Jul 14, 2026 • ⏱ 7 min read • Editorial policy
Did the doctor prescribe Amitriptyline pills for you too? Let's learn more about this medicine (Amitriptyline)
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Your doctor may have prescribed you a medication called Amitriptyline for depression, some nerve pain, or some other medical condition. It's normal to feel a little curious, and maybe even nervous, when starting a new medication. That's why we thought we'd talk about this medication today, what it does, and what to be careful about when using it. Being well-informed about your medication is one of the best steps to getting well soon.

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What exactly is Amitriptyline?

Simply put, Amitriptyline is a medication that is mainly used to treat mental health conditions like depression. Our brains have natural chemicals that control things like happiness and calmness. We call these neurotransmitters. Serotonin and Norepinephrine are two such important neurotransmitters.

In conditions like depression, these chemicals can become less effective. So this medication works by restoring the levels of these chemicals in the brain and helping to improve your mood. It belongs to a class of drugs called tricyclic antidepressants (TCAs) . In addition to depression, doctors also prescribe this medication for other conditions, such as chronic pain related to certain nerves and migraine prevention.

Things you need to tell your doctor before starting this medication

This is a very important point. For your safety, you should tell your doctor about any medical conditions you have before starting this medication. If you have any of the conditions listed in the table below, be sure to tell them about it.

Do you have these conditions? Why is it important to tell the doctor?
Heart disease, an irregular heartbeat, or a previous heart attack. Because this medicine can affect the heartbeat.
Glaucoma condition. It can increase eye pressure and worsen glaucoma.
Liver disease. The process of removing the medicine from the body may be affected.
Prostate problems or difficulty urinating. Difficulty urinating may increase.
Seizures or convulsions. The risk of seizures may increase.
Overactive thyroid. The risk of heart rate-related side effects may increase.
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How should I use the medicine?

Just as the doctor told you, it is very important to take the correct dosage at the correct time.

  • It's okay to take the pill with a glass of water.
  • There is no problem taking it before or after meals.
  • The most important thing is, even if you feel better, do not stop taking the medication suddenly without your doctor's advice. If you do, your symptoms may return or you may experience withdrawal symptoms. If you do stop, do so according to your doctor's advice, gradually reducing the dose.

Let's say I forget to take my pill. It's okay to take it as soon as I remember. But if it's almost time for the next dose, skip the missed dose and take the next one at the scheduled time. Never take two pills at once just to make up for a forgotten dose.

What to do if you take too much medicine?

If you think you have accidentally taken more than the prescribed dose, do not take it lightly. Go to the nearest hospital Emergency Department (ETU) immediately . Or call the National Poisons Information Centre at the Colombo National Hospital (telephone number 0112686143) for advice.

What are the things to be careful about when taking medication?

To get the most out of the medicine, pay attention to these points as well.

  • It takes time to see results: It can take several weeks for this medicine to have its full effect. So, don't stop taking it because you think, "There's no difference yet." Keep taking it as long as your doctor tells you to.
  • Watch for mood changes: This is very important. Especially when you first start taking the medication, if you or your family members notice that you are feeling increasingly sad, anxious, or have suicidal thoughts , please let your doctor know right away. Also, watch for sudden changes such as agitation, irritability, or hyperactivity.
  • Drowsiness and dizziness: This medication may cause drowsiness and dizziness. So , avoid driving or operating machinery until you know how it affects you. Be careful when getting up from a sitting position, especially if you are elderly.
  • Avoid alcohol: Avoid drinking alcohol completely. Alcohol can increase the side effects of the medication, especially drowsiness.
  • Dry mouth: You may feel like your mouth is dry. This can be controlled by chewing sugar-free gum, sucking on sugar-free candy, and drinking plenty of water throughout the day.
  • Constipation: Some people may experience constipation. Eating foods high in fiber (fruits, vegetables), drinking water, and exercising can help. If you have not had a bowel movement for more than 3 days, tell your doctor.
  • Be careful with the sun: This medication can make your skin sensitive to the sun. Therefore, if you are going to be in the sun, it is a good idea to use an umbrella, wear clothing that covers your body, and apply sunscreen.

Side effects that may occur due to medication

Like any medicine, Amitriptyline can cause side effects in some people. While most of these are not serious, there are some symptoms that we should be especially concerned about.

🚨 Symptoms that should be reported to the doctor immediately
Allergic reactions Skin rash, itching, swelling of the face, lips, tongue, difficulty breathing.
Changes in heart rate Feeling like your heart is beating fast, irregular heartbeat, dizziness, chest pain.
Serotonin Syndrome Restlessness, confusion, muscle stiffness, tremors, excessive sweating, fever, vomiting, diarrhea.
Changes in eyesight Sudden eye pain, blurred vision, and seeing rings around lights.
Worsening of mental state Increased depression, suicidal thoughts.
🙂 Symptoms that are usually not serious, but should be reported to the doctor if they persist
  • Drowsiness
  • Dry mouth
  • Obstruction
  • Dizziness
  • Changes in appetite or body weight
  • Change in sexual desire or activity

How should you store your medicine?

Keep this medicine out of reach of children and pets.Store at room temperature, away from sunlight, in a dry place. Do not use expired medicine.

💡 Take-Home Message

  • Amitriptyline is a medication that should be used only under the advice of a doctor.
  • Be sure to tell your doctor about any other illnesses you have or any other medications you are taking.
  • Do not stop taking the medication on your own or change the dosage.
  • Be careful when driving or doing other tasks that require concentration, as drowsiness and dizziness may occur. Avoid drinking alcohol.
  • If you experience increased anxiety, suicidal thoughts, or severe side effects, seek medical advice immediately.
❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

What to do if you take too much medicine?

If you think you have accidentally taken more than the prescribed dose, do not take it lightly. Go to the nearest hospital Emergency Department (ETU) immediately . Or call the National Poisons Information Centre at the Colombo National Hospital (telephone number 0112686143) for advice.

How should you store your medicine?

Keep this medicine out of reach of children and pets.Store at room temperature, away from sunlight, in a dry place. Do not use expired medicine.

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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.