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How to cleanse your colon for a colonoscopy with CLENPIQ: What you need to know!

MBBS
Medically Reviewed by MBBS ✓ Medically Reviewed
📅 Updated: Aug 20, 2026 • ⏱ 3 min read • Editorial policy
How to cleanse your colon for a colonoscopy with CLENPIQ: What you need to know!
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Are you having a colonoscopy soon? If so, your doctor may have told you to cleanse your colon beforehand. Most often, a medicine called CLENPIQ is used for this. This is to explain to you in simple terms exactly how to do this. Don't worry, we'll talk about everything in detail.

How to cleanse your colon for a colonoscopy with CLENPIQ: What you need to know! Infographic
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What is CLENPIQ? Why is it important?

Simply put, CLENPIQ is a medicine that cleanses your large intestine, or colon, completely. It contains sodium picosulfate, magnesium oxide, and citric acid. These ingredients work together to cleanse your colon thoroughly.

So, why is this bowel prep so important? Think about it, a colonoscopy is when the doctor puts a camera inside your colon and looks at it. If there are any food particles or waste in the colon, it won't be possible to examine it properly, right? It's like driving a car on a muddy road on a rainy day. You can't see anything clearly.

But if the bowel is well cleansed, the doctor can clearly see even small polyps that could lead to cancer. It's like driving on a sunny day on a good road. That's why this bowel preparation step is so important. If it's not done properly, you may have to do a colonoscopy again at some point.

How to use CLENPIQ?

CLENPIQ usually comes in a drinkable liquid form, in a small bottle. You will need to take two bottles of this. One the day before the test, and the other the morning of the test. The most important thing is to follow the instructions your doctor gives you exactly as instructed. If you don't do this exactly, the test may be invalidated.

❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

ukat juk’ampinaka ¿Kunjamsa CLENPIQ ukax lurasiñapa?

ukat juk’ampinaka Ukax pä dosis split) ukanw churasi. Nayrïr dosis ukax jayp’uruw janïr yant’äw lurañkamax apsutäñapa, payïr dosis ukax alwaw 5-9 horanak janïr yant’äw lurañkamax apsutäñapa, ukxarusti sapa mayniw 5 tasa umamp yapxatatäñapa.

ukat juk’ampinaka ¿Qhawqha pachas CLENPIQ uk umasax intestinonakax sarnaqapxi?

ukat juk’ampinaka Jilapachax 1-3 horanak qulla umañ tukuyatatx purakax ch’amakt’iwa ukat sapa kutiw heces uñstayañ qalltaraki.

¿Kunjamatsa uka qulla apnaqañkamax jan deshidratación ukar puriñax wakisispa?

ukat juk’ampinaka Uka qulla umañat sipansa, sapa horaw mä taza uma, coco uma, jan ukax q’uma uma umañama.

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PubMed / WHO

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  1. Your bowel needs to be completely empty so the doctor can see clearly.
  2. Follow the instructions given by your gastroenterologist exactly.
  3. Do not eat any solid foods the day before your colonoscopy. Only drink clear liquids. Continue drinking these clear liquids until 3 hours before the test.
  4. Get your bowel preparation kit from the pharmacy at least five days before your colonoscopy.
  5. Blood thinners: If you are taking these medications, talk to your doctor about them at least two weeks before the test. Examples include: clopidogrel (Plavix®), warfarin (Coumadin®), ticlopidine hydrochloride (Ticlid®), anagrelide (Agrylin®), rivaroxaban (Xarelto®), dabigatran (Pradaxa®), apixaban (Eliquis®), and prasugrel (Effient®).
  6. Insulin and diabetes medication: Always talk to your doctor about adjusting your dose in the days before your colonoscopy. Do not take your diabetes medication after midnight on the day of your test. If you take insulin (such as insulin glargine injection (Lantus®), insulin lispro (Humalog®), long-acting insulin such as insulin isophane (HumulinN®, NovolinN®, ReliOn®), or 70/30 insulin), you should take only half of your usual dose the day before your test.
  7. Weight management medication: If you are taking weight management medication, you may need to adjust the dose or stop taking it a few days/weeks before the test. Ask your doctor for more information. Some medications that you may need to stop taking include: canagliflozin (Invokana®), dapagliflozin (Farxiga®, Forxiga®), dulaglutide (Trulicity®), empagliflozin (Jardiance®), ertugliflozin (Steglatro®), exenatide (Byetta®, Bydureon®), liraglutide (Victoza®, Saxenda®), lixisenatide (Adylyxin®), semaglutide (Ozempic®, Wegovy®, Rybelsus®), and tirzepatide (Mounjaro®, Zepbound®).
  8. Iron pills: Stop taking these a week before your colonoscopy.
  9. Popcorn
  10. Beans
  11. Nuts (e.g. flax seeds, sunflower seeds, quinoa)
  12. Multigrain bread
  13. Nuts (like cashews, peanuts)
  14. Lettuce/vegetables (eaten raw)
  15. Fresh and dried fruits
  16. Things you can drink: water, salted porridge (well filtered), clear soup (no oil, no chunks), fruit juice (no fiber, e.g. apple juice, grape juice - no red), tea/coffee (no milk, cream), jelly (no red, purple, orange), sweet drinks (clear ones like soda).
  17. Things not to drink: Milk and dairy products, cream, fruit juices with fiber, red, purple, orange colored liquids (as these can look like blood in the intestines), alcohol.
  18. Drink one bottle of CLENPIQ completely.
  19. Over the next three hours, drink at least five additional 8-ounce (240 ml) glasses of clear liquids (that means water, broth, etc.).
  20. Drink the second bottle of CLENPIQ completely.
  21. Within the next hour, drink at least four additional 8-ounce (about 240 ml) glasses of clear liquids.
  22. You can drink clear liquids up to three hours before the test.
  23. If you have a medical condition that requires special care.
  24. If the colon cleansing was not done properly during a previous colonoscopy, or if it was unsuccessful.
  25. If you had any discomfort with anesthesia during a previous examination.
  26. NHS: Bowel Prep Instructions
  27. Mayo Clinic: Colonoscopy Prep Options
  28. Cleveland Clinic: Clenpiq Bowel Prep Guidelines
  29. FDA: Clenpiq Prescribing Information
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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.