Yala aw ka dɔgɔtɔrɔ ye ‘Antimetabolite’ fura dɔ sɛbɛn aw ye walima aw gɛrɛfɛ mɔgɔ dɔ ye walasa ka kansɛri bana furakɛ wa? N’o don, aw bɛ se ka fɛn bɛɛ dɔn fura suguya in kan, a nafa n’a dɛsɛ, ani a baara cogo. Banakisɛfagalanw ye fura suguya dɔ ye min bɛ kɛ chimiothérapie la walasa ka kansɛri faga. Tiɲɛ na, u ye fura suguya kɔrɔlenba ye min bɛ kɛ ka caya kansɛri furakɛli la, a bɛ kɛ kabini san 1940.
Nin farikolojɔlifɛn ninnu ye mun ye? U bɛ baara kɛ cogo di?
N’an y’a fɔ cogo nɔgɔman na, farikolojɔli dumuniw ye fura sugu dɔ ye min bɛ farikolokisɛw tiɲɛ (cytotoxic) . U ka wale bɛ kɛ cogo nɔgɔlen na kosɛbɛ.
Miiri k’a filɛ, an farikolo kɔnɔ selilu dɔ, kɛrɛnkɛrɛnnenya la kansɛri banakisɛ, mago bɛ a yɛrɛ ka ‘fɛn’ dɔw la walasa ka bonya, ka tila, ka caya. Nin fura in bɛ min kɛ, o ye ka kɛ ‘fɛn nkalonma’ ye min bɛ i n’a fɔ o fɛnw tigitigi. O la, kansɛribanakisɛw bɛ lafili ani u mago bɛ fɛn lakikaw nɔ na walasa u ka bonya, u bɛ nin fɛn nkalonma ninnu dun, n’o ye an ka fura ye.
Kɔnɔnatumu dɔ ka jamu kunnafoniw, o kɔrɔ ye ko o selilu ka jatebɔsɛbɛn dafalen bɛ sɔrɔ fɛnw na minnu bɛ wele ko ADN ni ARN . Ni nin farikolojɔli fura in donna kansɛribanakisɛ la, o farikolokisɛ tɛ se k’a ka ADN kopiw dilan. A bɛ i n’a fɔ ka karitɔn jugu bila sɛbɛnnikɛlan kɔnɔ, a tɛ se ka kopiw dilan.
Ni ADN tɛ se ka kopi kɛ, o selilɛri tɛ se ka tila ka kɛ selilu kura ye. Kansɛribanakisɛw bɛ caya dabila ka sa.
Ikomi nin fura sugu bɛ kɛrɛnkɛrɛnnenya la farikolokisɛw de laɲini minnu bɛ tila teliya la , u bɛ se kosɛbɛ kansɛriw kɛlɛli la minnu bɛ bonya joona.
Ninnu ye farikolojɔlifɛn dɔw ye minnu bɛ kɛ ka caya kansɛri furakɛli la.
| Banakisɛfagalan dɔw bɛ kɛ ka caya |
|---|
| 6-mɛrikaptopurini (mercaptopurine) ye |
| Fludarabine (Fludarabine) ye |
| 5-fluorouracil (fluorouracil) ye |
| Jemcitabine (Jɛmisitabini). |
| Sitarabini (Sitarabini). |
| Pemetrexed (Pemetrexed) bɛ sɔrɔ a la |
| Metɔtiriksati (méthotrexate) (méthotrexate). |
Nin fura in bɛ kɛ kansɛri suguya jumɛnw na?
farikolo tangalanw bɛ kɛ ka joli kansɛriw furakɛ ka caya i n' a fɔ jolidɛsɛ , sinji kansɛri , kɔnɔbara kansɛri , ani banakɔtaa kansɛri .
Nka ikomi o furaw bɛ se ka farikolokisɛ suguya o suguya falen teliya la, dɔgɔtɔrɔw fana b’u fɔ kansɛri suguya wɛrɛw la.
Ne bɛ se ka fura in sɔrɔ cogo di?
Farikoloɲɛnajɛ furaw dicogo bɛ se ka ɲɔgɔn ta ka kɛɲɛ ni fura min kofɔlen don ani kansɛri suguya min bɛ furakɛ.
- Kisɛw walima jilamaw: Farikoloɲɛnajɛ fura dɔw bɛ sɔrɔ furakisɛw walima jilamaw ye minnu bɛ se ka ta da la don o don.
- jolisira fɛ (IV): Pikiri suguya wɛrɛw bɛ yen minnu bɛ kɛ jolisira dɔ la. A ka ca a la, olu bɛ di i n’a fɔ kɔgɔjila jolisira fɛ. Mɔgɔ minnu bɛ furakɛli kuntaalajan na, o fura ninnu bɛ di tuma dɔw la tubabufura kɛrɛnkɛrɛnnen dɔ fɛ (mediport) min bɛ bila jolisira belebeleba dɔ la min bɛ cɛmancɛ la.
- Kɛrɛmuw : Farikolofagalan minnu bɛ kɛ fari kansɛri la, olu fana bɛ sɔrɔ kiribiw ye minnu bɛ kɛ fari la. Olu bɛ kɛ fari yɔrɔ min bananen don siɲɛ kelen walima siɲɛ fila tile kɔnɔ.
Nin furakɛli in nafa ni a farati jumɛnw bɛ a la?
Nin fura suguya in nafa ka bon kosɛbɛ, o ye ko a bɛ kansɛribanakisɛw tiɲɛ, ka kansɛri falenni jɔ walima k’a dɔgɔya. O bɛ banabagatɔ dɛmɛ a ka kɛnɛya ani ka a si janya.
Nka, farati dɔ b’o la. Nin fura ninnu tɛ baara kɛ kelen ye bɛɛ la. Tuma dɔw la, hali dɔgɔtɔrɔw bɛ gɛlɛya sɔrɔ k’a dɔn tigitigi fura in bɛnnen don kansɛri min ma.
Fɛn wɛrɛ min nafa ka bon, o ye ko tuma dɔw la, hali ni a bɛ baara kɛ ka ɲɛ a daminɛ na, waati tɛmɛnen kɔfɛ, kansɛribanakisɛw bɛ deli fura in na. An b’o Weele ko ‘resistant’. O kɔ, fura tɛ se ka baara kɛ tuguni.
Farikoloɲɛnajɛ furaw kɔlɔlɔ jumɛnw bɛ yen?
Ikomi farikolo tangalanw ye fura suguya dɔ ye, fura kelen tɛ, a kɔlɔlɔw bɛ se ka ɲɔgɔn ta. O la, ni farikolojɔli fura kɛrɛnkɛrɛnnen dɔ sɛbɛnna aw ye, a nafa ka bon aw ka kuma dɔgɔtɔrɔ fɛ kɔlɔlɔ kɛrɛnkɛrɛnnenw kan minnu bɛ sɔrɔ a la.
Nka a ka ca a la, kɔlɔlɔ damadɔ bɛ yen minnu ka teli ka ye farikolojɔli fura fanba la.
| Kɔnɔnafili | Cogojirali |
|---|---|
| Dumunikɛcogo gɛlɛyaw | Dusukunnata, fɔɔnɔ, dumunikɛbaliya, kɔnɔboli, walima kɔnɔboli. |
| Farikolo lafiyabaliya | Sɛgɛn, barikantanya, farikolodimi, kungolodimi ani ɲɛnamini. |
| Yɛlɛma donna da ni dawolo la | Joli walima funu da ni dawolo la. |
| A bɛ nɔ bila sugunɛ na | Sugunɛbilenni (enzymes) caman sɔrɔli (o bɛ se ka kɛ sababu ye ka sugunɛ tiɲɛ walima ka funu). |
| Fari ni kunsigi | Kunsigi bɔli, fari kurulenw, fari jalen ni karilen. |
| Yɛlɛma donna ɲɛw la | Yeli bɛ Changé walima ka yeelen dɔn. |
| A bɛ nɔ bila joli kuruw la | Joli kuru finmanw hakɛ dɔgɔyali, o bɛ dɔ fara banakisɛ sɔrɔli kan. |
Take-Home cikan
- Banakisɛfagalanw ye chimiothérapie fura sugu dɔ ye min bɛ kansɛribanakisɛw lafili walasa u ka bonya ani k’u bali ka o kɛ.
- Olu ka teli ka kɛ kansɛriw la minnu bɛ bonya joona i n’a fɔ jolidɛsɛ, sin, kɔnɔbara ani kɔnɔbara kansɛri.
- Hali ni nafa bɛ nin furakɛli ninnu na ka kansɛribanakisɛw tiɲɛ, faratiw fana bɛ u la i n’a fɔ fura tali ni kɔlɔlɔw.
- Ikomi kɔlɔlɔw tɛ kelen ye furaw ni furaw cɛ, a nafa ka bon aw ka fura minnu ta ani a nɔfɛkow dɔn.
- Min nafa ka bon kosɛbɛ: Aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ k’a sɔrɔ aw ma sigasiga fura minnu dira aw ma, a kɔlɔlɔw, ani ɲininkali walima haminanko minnu bɛ se ka kɛ aw la. Ale kelenpe de bɛ se ka laadilikanw di i ma minnu bɛnnen don kosɛbɛ.
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