Yala ‘Sulfa’ furaw dira aw ma wa? An ka kunnafoni wɛrɛw sɔrɔ o Sulfonamides ninnu kan!

Yala dɔgɔtɔrɔ dɔ delila ka fura suguya dɔ sɛbɛn aw ye aw ka ɲɛnamaya kɔnɔ wa? N’a sɔrɔ i hakili b’a la, walima n’a sɔrɔ i yɛrɛ y’o mɛn. Ni mɔgɔ fanba ye "sulfa" daɲɛ mɛn, u b’a miiri ko fura kelen de don. Nka tiɲɛ na, a ye fura kuluba dɔ tɔgɔ ye min bɛ wele ko generic. O la bi, an ka kuma nin sulfonamide ninnu ye mun ye, u bɛ min kɛ, ani fɛn minnu nafa ka bon kosɛbɛ aw ka kan ka minnu dɔn u ko la.

Nin sulfonamide ninnu ye mun ye tigitigi?

N’an y’a fɔ cogo nɔgɔman na, sulfonamides ye fura kulu ye minnu bɛ dilan laboratuwari kɔnɔ hadamadenw fɛ (synthétique). U tɛ sɔrɔ u yɛrɛ la. N’aw ye fura ninnu ka kemikaliya cogoya lajɛ, u bɛɛ yɔrɔ kelen bɛ yen min kɔnɔ, kisɛkisɛ fɛnɲɛnamafagalan bɛ sɔrɔ. O yɔrɔ de la "sulfonamide" tɔgɔ bɔra.

O la sa, fura ninnu bɛ baara kɛ cogo di? Aw ye miiri a la, banakisɛ minnu bɛ don an fari la, olu mago bɛ dumuni na walasa ka ɲɛnamaya ani ka jɛnsɛn. Nin banakisɛ ninnu mago bɛ balofɛn minnu na, olu dɔ ye folate ye, walima witamini B9 . Nin sulfafura ninnu bɛ min kɛ, o ye ka banakisɛw ka se ka foli in dilan. A bɛ iko kɔngɔ bɛ mɔgɔ la ni dumuni tɛ. Ni banakisɛw bɔnɛna folate la, u tɛ se ka tila walima ka bonya ka sa dɔɔni dɔɔni.

Sisan, i bɛ se ka miiri ko: “An fana mago bɛ folate la, o la, yala a tɛna kojugu kɛ an na wa?” O ye ɲininkali ɲuman ye dɛ! Nka anw, n’o ye hadamadenw ye, an mago bɛ folate min na, an bɛ o sɔrɔ an bɛ dumuni minnu dun. An tɛ folate dilan an farikolo la. O la, o furaw tɛ nɔ bila an ka farikolokisɛw la k’a ɲɛsin an ma o cogo la. O de kama u ye banakisɛfagalanw fagacogo ɲumanba ye.

Sulfa furaw nafa ka bon bi i n’a fɔ a tun bɛ cogo min na o waati la.

Sulfonamides tun tɛ banakisɛfagalan fɔlɔ ye min sɔrɔla. Nka u sɔrɔli kɔfɛ san 1930 waatiw la, u tun ye banakisɛfagalan suguya bɛɛ la ɲuman ni fangatigi ye min tun bɛ sɔrɔ san tan ɲɔgɔn kɔnɔ. Sani penisilini ka diya mɔgɔw ye, o sulfa furaw ye dɛmɛba lase mɔgɔ ma ka dɔ bɔ banakisɛfagalanw ka saya la.

Nka bi, sulfonamides tɛ kɛ ka banakisɛw dɔrɔn de furakɛ. Nin fura suguya in bɛ kɛ ka bana suguya caman furakɛ, i n’a fɔ sukarodunbana, tansiyɔn jiginni, sidabanakisɛ, ani kansɛri suguya dɔw.

Fura wɛrɛ jumɛnw bɛ sulfonamide kulu la?

Nin lisi in ka jan dɔɔni, nka a bɛna hakilina di aw ma fura ninnu nafa hakɛ la. An ka nin tila tila fila ye.

Yala ‘sulfa allergie’ maana ye tiɲɛ ye wa?

Ɔwɔ, faritanabana bɛ se ka kɛ sulfonamide furaw la. Diɲɛ kɔnɔ, mɔgɔ 3 ni mɔgɔ 8 cɛ, mɔgɔ 100 o 100, faritanabana bɛ olu la ni sulfa fura ye. Nka o bɛ tali kɛ faritanabana hakɛ la banakisɛfagalan wɛrɛw la minnu ka ca, i n’a fɔ penisilini.

Nka min nafa ka bon yan, o ye ko k’a sababu kɛ i fari tɛ sɔn sulfa fura kelen ma, i tɛna faritanabana sɔrɔ sulfa fura tɔw bɛɛ la . Misali la, mɔgɔ min fari tɛ sɔn banakisɛfagalan Bactrim ma, a ka ca a la kosɛbɛ ko a fari tɛ dimimadafura Celebrex ma. Sabula fura fila ninnu ka kemikaliya cogoya tɛ kelen ye.

O la, ni aw delila ka faritanabana sɔrɔ sulfa fura dɔ la, aw ye aw jija ka o fɔ aw ka dɔgɔtɔrɔ ye walasa a ka se ka fura wɛrɛ sɛbɛn min tɛ mɔgɔ tɔɔrɔ.

Yala kɔlɔlɔ walima farati dɔw bɛ fura in na wa?

I n’a fɔ fura tɔw bɛɛ, sulfonamides bɛ se ka kɛ ni nafa ni farati dɔw ye.

• Banakisɛw kunbɛncogo : Waati tɛmɛnen kɔfɛ, banakisɛ dɔw bɛ se ka kɛ fura ninnu ‘dɔlɔminna’ ye, ka u kɛlɛ. O kɔfɛ, fura bɛ baara dabila o banakisɛ in kan.
• Kɔnɔnatumu jugumanw : A man teli kosɛbɛ, mɔgɔ dɔw bɛ se ka faritanabana jugumanba sɔrɔ. Stevens-Johnson ka bana ni farikolojidɛsɛ toxic (toxic epidermal necrolysis) ye o bana jugu sugu fila ye, nka u man teli kosɛbɛ. Sani aw ka siran nin ɲɔgɔnna fɛn in na, a ka fisa aw ka kuma dɔgɔtɔrɔ fɛ aw bɛ fura min ta.

Yala Bactrim ye sulfonamide ye wa?

Ɔwɔ, a yɔrɔ dɔ la. Fura BactrimTM kɔnɔ, sulfamethoxazole bɛ sɔrɔ, sulfonamide dɔ, ani fura wɛrɛ min bɛ wele ko trimethoprim, o fana bɛ baara kɛ o cogo kelen na.

Yala Celebrex fana ye sulfa fura ye wa?

Awɔ. Celecoxib (Celebrex®) ye dimimadafura ye min bɛ sulfonamide suguya la.

Nin fura in bɛ se ka kɛ sababu ye ka kirisiw sɔrɔ sugunɛ na wa?

Sulufa fura dɔw bɛ se ka kɛ sababu ye ka kirisitaw sɔrɔ sugunɛ na. Nin tɛ kɔlɔlɔ ye min ka teli ka sɔrɔ. Ni dɔgɔtɔrɔ ye dɔ sɛbɛn aw ye, a bɛna a fɔ aw ye aw ka kan ka min kɛ walasa ka o bali (misali la, aw bɛ ji caman min). O la sa, kana hami o la.

Sulfonamides ye fura suguya ye min sɛgɛsɛgɛra kosɛbɛ ani min sɛgɛsɛgɛra, a tariku bɛ san 90 ni kɔ bɔ. A daminɛ na, u tun bɛ kɛ banakisɛw dɔrɔn de kama, sisan u bɛ kɛ ka bana suguya caman furakɛ k’a ta kunkolo la ka taa a bila senkɔniw na.