Mina míasrɔ̃ nu tso megbeƒu ƒe lãkusi ŋu ko.

Èbu míaƒe ŋutilã ƒe akpa sue nenie wɔa dɔ geɖe alea ŋu kpɔa? Egbea míele nu ƒom tso lãkusi sue aɖe ŋutɔ si wɔa nu wɔnuku geɖe ŋu. Woyɔa esia be pituitary gland. Vevietɔ la, míele míaƒe susu hem yi lãkusi ma ƒe megbekpa si nye ``Posterior Pituitary`` dzi.

Nukae nye pituitary gland sia? Nukae le etɔxɛ le megbekpa dzi?

Kpuie ko la, lãkusi nye lãkusi sue aɖe si lolo abe pea ene si le míaƒe ahɔhɔ̃ ƒe gɔme, le hypothalamus te. Enye míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe akpa vevi aɖe ŋutɔ. Bu eŋu kpɔ, togbɔ be ele sue hã la, ekpɔa ŋusẽ ɖe lãmetsi vevi geɖe siwo le míaƒe ŋutilã me dzi.

Pituitary gland sia ƒe akpa vevi eve li:

1. Ŋgɔgbe ƒe Lobe

2. Posterior Lobe - Esiae nye nusi ŋu míele nu ƒom tsoe egbea, ``Posterior Pituitary``.

Pituitary gland la wɔa lãmetsiŋusẽ geɖe eye wòɖea wo ɖe go. Gake megbeƒu si woyɔna be pituitary la le etɔxɛ. Lãmetsiŋusẽ siwo pituitary gland wɔna la dometɔ eve koe wòdzrana ɖo heɖea wo ɖe go ne ehiã. Lãmetsiŋusẽ eve siawoe nye:

• Oxytocin ƒe atike
• Lãmetsiŋusẽ si tsia tsinyegoe me (ADH), si woyɔna hã be Vasopressin.

Fifia ɖewohĩ ànɔ eŋu bum be, "Ekema nukae nye hypothalamus sia?" Hypothalamus hã nye míaƒe ahɔhɔ̃ ƒe akpa aɖe. Ekpɔa ŋusẽ ɖe nu geɖe dzi, siwo dometɔ aɖewoe nye ʋu ƒe sisi, dzi ƒe tsotso, ŋutilã ƒe dzoxɔxɔ, kple nuɖuɖumeŋusẽ. Nukutɔe la, atikutsetse sue aɖe do ƒome kple lãkusi si woyɔna be pituitary gland kple hypothalamus. Woyɔa esia be pituitary stalk. To atikutsetse sia dzie hypothalamus gblɔna na pituitary gland be, "Enyo, ɖe asi le lãmetsi ma ŋu fifia."

Nukae Nye Dɔlékuiwutikewo ƒe Dɔwɔɖoɖo? Taflatse ɖe eme vie.

Nyabiase nyui aɖe! Dɔlékuiwutikewo nye lãkusi siwo le míaƒe ŋutilã me siwo wɔa atike siwo woyɔna be lãmetsiŋusẽwo eye woɖea wo ɖe ʋukawo me tẽ.

Lãmetsiŋusẽwo le abe dɔla siwo tsɔa gbedasiwo yia míaƒe ŋutilã me ene. Wozɔa mɔ to ʋukawo me hegblɔa nusi wòle be míawɔ kple ɣeyiɣi si míawɔe na míaƒe ŋutinuwo, ŋutigbalẽ, lãmekawo, kple lãmenugbagbevi bubuwo.

Lãmetsiŋusẽ kple ŋutinu vevi siwo wɔ míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔe nye:

• Hypothalamus ƒe ʋuʋudedi
• Pituitary Gland ƒe Ʋuka
• Lãmetsiŋusẽ ƒe lãkusi `(Thyroid)`
• Parathyroid lãkusiwo
• Adrenal ƒe lãkusiwo
• Pineal ƒe lãkusi
• Dɔgbo ƒe dɔléle
• Ovaries (le nyɔnuwo me) .
• Vidzidɔ (vidzidɔ) (ŋutsu) .

Lãmetsi kawoe dona le megbeƒu ƒe lãkusi me? Nukae wowɔna?

Abe alesi míegblɔe va yi ene la, megbeƒu ƒe lãkusi dzraa lãmetsiŋusẽ ƒomevi vevi eve ɖo heɖea wo ɖe go. Le nyateƒe me la, hypothalamus ye wɔa lãmetsi siawo. Gake wodzraa wo ɖo heɖea asi le wo ŋu ne megbe lãkusia hiã.

1. Lãmetsiŋusẽ si tsia tsinyegoe me (ADH) alo Vasopressin:

• Lãmetsiŋusẽ sia le vevie ŋutɔ. Lãmetsiŋusẽ siae kpena ɖe ŋutilãa ŋu wòxɔa tsi agbɔsɔsɔme si hiã ne míaƒe ayikuwo le ʋua ƒom. Kpuie ko la, ADH kpena ɖe mía ŋu míeɖua tsi ƒe dadasɔ le míaƒe ŋutilã me dzi.

2. Oxytocin ƒe dɔlékuiwo:

• Le nyɔnuwo gome la, ekpena ɖe vidzidzi ŋu to vidzidɔa ƒe ʋuʋu le vidzidzi me me. Eʋãa nowo hã be woawɔ notsi. Oxytocin kpɔa ŋusẽ ɖe kadodo si le vidada kple vi dome hã dzi.
• Le ŋutsuwo gome la, lãmetsi sia ate ŋu akpɔ ŋusẽ ɖe kadodo si le dzilawo kple ɖeviwo dome hã dzi. Menye ema ɖeɖeko o, ke oxytocin hã kpena ɖe ame ŋu wòtutua tsinyenye kple tsinyenye ƒe tsi yia ŋgɔ le tsinyenye me.

Eyata nukae nye dɔ vevitɔ si megbe ʋuka si woyɔna be pituitary wɔna?

Nu vevitɔe nye be woadzra oxytocin kple antidiuretic hormone (ADH) ɖo eye woaɖe wo ɖa ne dzesi aɖe tso hypothalamus gbɔ. Hypothalamus ɖoa dzesi siawo to lãmeka ƒe dzesi siwo toa pituitary stalk si ŋu míeƒo nu tsoe va yi dzi.

Aleke Posterior Pituitary do ƒome kple ŋutinu bubuwoe?

Esia nye ŋutinya dodzidzɔname aɖe ŋutɔ. Megbe lãkusia do ƒome kple hypothalamus tẽ. Elabena hypothalamus wɔa oxytocin kple ADH eye wògblɔa ɣeyiɣi si woaɖe asi le wo ŋu na wo.

Kpeɖe eŋu la:

• Oxytocin wɔa dɔ kple vidzidɔ, no me lãkusiwo (nowo), kple ʋuka siwo me ʋu sina tona le ŋutsuwo me.
• Míaƒe ayikuwo koŋue wɔa dɔ kple ADH (antidiuretic hormone) .

Afikae megbeƒu si woyɔna be pituitary le? Aleke gbegbee wòloloe?

Pituitary gland le míaƒe ahɔhɔ̃a ƒe gɔme, le míaƒe ŋɔti ƒe tɔdzisasrã megbe, le hypothalamus te tẽ. Enɔa teƒe sue aɖe si le ƒu si woyɔna be sphenoid la me. Woyɔa esia be Sella Turcica.

Pituitary gland bliboa ƒe lolome anɔ abe pea ene, anɔ abe sentimeta 1/3 ene. Posterior pituitary nye lãkusia ƒe akpa si dze ŋgɔ megbe. Ele sue wu ŋgɔgbe lãkusi. Anterior pituitary xɔa abe 80% le pituitary gland bliboa ƒe kpekpeme me.

Dɔléle kple nɔnɔme kawoe bɔ siwo do ƒome kple Posterior Pituitary?

Kuxi vevi siwo ate ŋu ado mo ɖa le megbeƒu ŋue nye oxytocin alo antidiuretic hormone (ADH) ƒe dodo fũ alo eƒe dodo fũu akpa.

Nɔnɔme siawo ƒe akpa gãtɔ mebɔ o. Azɔ hã, dɔdzẽ ate ŋu agblẽ nu le megbeƒu ƒe lãkusi ŋu, gake ƒã hã. Pituitary tumors dona zi geɖe le pituitary gland si le ŋgɔgbe me.

Lãmetsiŋusẽ si tsia tsinyegoe me (ADH) ƒe dodo fũu akpa .

Esia tsoa ADH ƒe wɔwɔme dzi ɖeɖe kpɔtɔ le hypothalamus me alo ADH ƒe dodo tso pituitary gland me dzi ɖeɖe kpɔtɔ gbɔ. Zi geɖe la, nusi gblẽna le hypothalamus alo megbe lãkusi ŋu gbɔe esia tsona. Ɣeaɖewoɣi la, domenyiŋusẽfianu ƒe tɔtrɔ hã ate ŋu atsoe. Le go aɖewo me la, womenya nusi gbɔ wòtso o.

Ne ADH ƒe agbɔsɔsɔ ɖiɖi wu alesi wòle dzɔdzɔmee la, ayikuawo mete ŋu gbugbɔa tsi agbɔsɔsɔme si wòhiã o. Esia wɔnɛ be tsi geɖe dona le aɖuɖɔ me (aɖuɖɔa va nɔa ʋeʋẽm), si wɔnɛ be tsi si le ʋua me dzi ɖena kpɔtɔna eye wòdzia ​​eƒe agbɔsɔsɔ ɖe edzi.

ADH ƒe anyimanɔmanɔ ateŋu ahe tsi ƒe asitɔtrɔ ƒe dɔléle si mebɔ o si woyɔna be ``Central Diabetes Insipidus - CDI'' vɛ. Mele be woatɔtɔ esia kple ``Suklidɔ'' o, elabena wo ame evea to vovo kura. CDI ate ŋu ade ame ƒe agbe afɔku me ne womewɔ atike nɛ nyuie o.

CDI ƒe dzesiwoe nye:

• Aɖuɖɔtoe enuenu `(Polyuria)`
• Tsikɔwuame si gbɔ eme (Polydipsia) .
• Ðeɖiteameŋu (ele be nàfɔ zi geɖe le zã me hafi aɖu aɖuɖɔ) .
• Tsikuɖiɖi

Lãmetsiŋusẽ si tsia tsinyegoe me (ADH) ƒe dodo fũ akpa .

Esia tsoa ADH wɔwɔ ƒe dzidziɖedzi le hypothalamus me alo ADH ƒe dodo tso megbe lãkusi me ƒe dzidziɖedzi gbɔ. Woyɔa nɔnɔme sia be `(Syndrome of Inappropriate Antidiuretic Hormone secretion - SIADH)`. Ne ADH ƒe agbɔsɔsɔ dzi ɖe edzi la, tsi geɖe nɔa ŋutilãa me. Emegbe aɖuɖɔa va ƒoa ƒu ŋutɔ, eye ʋua va zua tsi eye wòtsina.

Susu geɖewo li siwo tae SIADH kple ADH ƒe agbɔsɔsɔ ate ŋu adzi ɖe edzi ɖo. Nusiwo gbɔ wòtsona zi geɖe dometɔ aɖewoe nye:

• Atike aɖewo (e.g., suklidɔ ƒomevi eve ƒe atike aɖewo, atike siwo wozãna na asrãdɔ) .
• Amekoko siwo wowɔna le atike si naa alɔ̃dɔdɔ ame katã me
• Ahɔhɔ̃ me dɔlélewo (abi, dɔlékuiwo, ʋusɔgbɔdɔ) .
• Ahɔhɔ̃mekoko siwo me ahɔhɔ̃mekawo ƒe dɔwɔwɔ le

Zi geɖe la , sodium ƒe agbɔsɔsɔ si le ʋu me gbɔe ADH ƒe agbɔsɔsɔ si dzina ɖe edzi ƒe dzesiwo tsona. Dzesi siwo fia be sodium mesɔ gbɔ ɖe ʋu me o dometɔ aɖewoe nye:

• Aɖuɖɔtoe kple ʋuʋudedi
• Taɖuame (taɖuame) .
• Dadasɔ ƒe bu (ɖewohĩ eƒe anyidzedze) .
• Susu me tɔtrɔ (tɔtɔ, ŋkuɖoɖonudzi ƒe gbɔdzɔgbɔdzɔ) .

Oxytocin ƒe dodo le lãme na ame

Esia nye nɔnɔme si mebɔ kura o.Ne oxytocin ƒe agbɔsɔsɔ ɖiɖi wu alesi wòle be wòanɔ la, vidzidɔa dzudzɔa ƒoƒo eye notsi la tsia dzodzodzoe le vidzidzi me. Togbɔ be ƒã hã la, nusi gbɔ esia tsona wue nye nɔnɔme si woyɔna be ``Panhypopituitarism.'' Esia nye esime lãmetsiŋusẽ siwo katã le lãkusi me ƒe agbɔsɔsɔ le sue wu alesi wòle.

Oxytocin ƒe dodo fũu akpa

Esia hã mebɔ kura o. Woyɔa esia be aɖi si nye oxytocin. Ne oxytocin ƒe agbɔsɔsɔ sɔ gbɔ wu alesi wòle dzɔdzɔmee la, vidzidɔa va wɔa dɔ akpa. Vidzidɔa ƒe lãmekawo dzina ɖe edzi (hypertrophy), eye teƒe mesɔ gbɔ na fugboea le vidzidɔa me o, si ate ŋu axe mɔ ɖe fufɔfɔ nu.

Ðe dodokpɔ aɖewo li siwo ate ŋu alé ŋku ɖe nye megbeƒu ƒe lãmesẽ ŋua?

Ne dzesi siwo do ƒome kple kuxi siwo le megbeƒu ƒe lãkusi ŋu le ŋuwò la, wò ɖɔkta ate ŋu aɖe gbe be woado ADH kple/alo oxytocin ƒe agbɔsɔsɔ kpɔ.

• ADH ƒe ʋudodokpɔ ate ŋu akpe ɖe ame ŋu woade dzesi ADH ƒe anyimanɔmanɔ alo esi gbɔ eme eye woake ɖe nusi gbɔ wòtso ŋu.
• Woate ŋu ado wò oxytocin ƒe agbɔsɔsɔ kpɔ le tsi vovovowo abe aɖuɖɔ, ʋu, ʋumenugbagbeviɣi, aɖuɖɔ, kple ahɔhɔ̃metsi ene me.

Ne dodokpɔa me tsonu mesɔ o la, wò ɖɔkta ate ŋu ado susu ɖa be nàwɔ nɔnɔmetatawo ƒe dodokpɔ, abe MRI (Magnetic Resonance Imaging) ene, be woatsɔ alé ŋku ɖe wò lãkusi si le ʋuka me ŋu.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne dzesiwo le ŋuwò be `(Central Diabetes Insipidus - CDI)` alo `(Syndrome of Inappropriate Antidiuretic Hormone secretion - SIADH)` la, kpɔ egbɔ be yeyi ɖɔkta gbɔ.

Ðo ŋku edzi be lãmesẽkuxi akpa gãtɔ siwo do ƒome kple megbeƒu ƒe dɔlélewo mebɔ o. Gake ne dzesi yeyewo alo dzimaɖitsitsi le ŋuwò la, anyo wu be nàƒo nu kple ɖɔkta. Woate ŋu awɔ dodokpɔ bɔbɔe ʋɛ aɖewo atsɔ akpɔ wò lãmesẽ.

Nu vevitɔ kekeake siwo dzi wòle be míaɖo ŋkui tso nusiwo ŋu míeƒo nu tsoe me (Take-Home Message) .

Enyo, eyata mele mɔ kpɔm be fifia miese akpa sue sia si le vevie ŋutɔ si woyɔna be ``Posterior Pituitary'' si ŋu míeƒo nu tsoe egbea la gɔme nyuie. Kpuie ko la:

• Megbe lãkusi nye lãkusi si le míaƒe ahɔhɔ̃ me ƒe megbekpa.
• Lãmetsiŋusẽ eve siwo woyɔna be oxytocin kple antidiuretic hormone (ADH) koŋue wòdzrana ɖo heɖea wo ɖe go. Hypothalamus ye wɔa lãmetsiŋusẽ siawo.
• ADH kpena ɖe mía ŋu míeɖua tsi ƒe dadasɔ le míaƒe ŋutilã me dzi .
• Oxytocin le vevie na vidzidzi, no nana, kple amegbetɔ ƒe kadodo .
• Lãmetsiŋusẽ siawo ƒe tɔtrɔ ateŋu ahe lãmesẽkuxiwo vɛ (togbɔ be ƒã hã) abe ``Central Diabetes Insipidus - CDI'' kple ``SIADH'' ene.
• Ne dzesi aɖewo siwo mebɔ o le ŋuwò la, nunya anɔ eme be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Míaƒe ŋutilã wɔ nuku ŋutɔŋutɔ, alo? Ewɔ nuku ŋutɔ be nàbu dɔ geɖe si woate ŋu awɔ kple akpa sue ma gbegbe ŋu!

` Pituitary gland, megbe pituitary, lãmetsiwo, oxytocin, antidiuretic hormone, ADH, lãmenugbagbeviwo ƒe dɔwɔwɔ