Nusi wòle be nànya tso Adenoid Cystic Carcinoma (ACC) ŋu!

Ne ède dzesi nane si mebɔ o abe ƒunukpeƒetetedɔ ene le wò ŋutilã ƒe teƒe aɖe, ne mevee o hã la, esɔ be vɔvɔ̃ naɖo ŋuwò vie alo nàdi be yeanya nu, alo? Alo ne nane abe wò gbe ƒe tɔtrɔ alo nu mimi sesẽ ene gakpɔtɔ li la, míetsia dzimaɖi vie. Le ɣeyiɣi siawo tɔgbe me la, ele vevie ŋutɔ be míanya kansa ƒomevi sia si mebɔ o si ŋu míele nu ƒom tsoe egbea si woyɔna be adenoid cystic carcinoma, alo ``ACC'' kpuie.

Nukae nye adenoid cystic carcinoma (ACC)? Mina míase egɔme bɔbɔe!

Kpuie ko la, Adenoid Cystic Carcinoma nye kansa ƒomevi si mebɔ kura o, si fia be mebɔ o. Zi geɖe la, edzɔna le míaƒe aɖuɖɔtoewo me alo le teƒewo abe ta kple kɔ ene. Gake ɣeaɖewoɣi la, ate ŋu adze le ŋutilã ƒe akpa bubuwo, le kpɔɖeŋu me, le ŋutigbalẽ, no me lãkusi, vidzidɔ, alo ʋuka me.

``(ACC)`` ƒe dɔdzẽ siawo li, woateŋu anye sesẽ, goglo, do. Woate ŋu akpɔ do ƒe dzedzeme gɔ̃ hã, abe ``Swiss cheese`` ma ene . Bu eŋu kpɔ, kansa lãmenugbagbevi siawo ƒe nuwɔna to vovo vie.

Zi geɖe la , ACC ƒe dɔdzẽ siawo tsina vivivi . Eyae nye be wometsina ŋutɔ zi ɖeka o. Gake le ɣeyiɣi aɖe megbe la, woate ŋu azu adãtɔwo ŋutɔ eye woawɔ nu le mɔ si womate ŋu agblɔ ɖi o nu . Ema fia be ne woɖe kansa la ɖa to amekoko me hã la, anɔ eme be wòagava emegbe. Le nyateƒe me la, ame geɖe siwo ŋu adenoid cystic carcinoma le la gadzena le ƒe atɔ̃ va ɖo ewo me. Esia tae, ne wokpɔ dɔléle sia le ŋuwò la, ele vevie be nàyi edzi awɔ fotowo kple dodokpɔwo be woalé ŋku ɖe wò nɔnɔmea ŋu.

Aleke gbegbee nɔnɔme sia bɔe? Ðe wòle be matsi dzia?

Le nyateƒe me la, adenoid cystic carcinoma nye kansa ƒomevi aɖe si mebɔ kura o . Exɔa ta kple kɔ me dɔdzẽwo katã ƒe 1% lɔƒo. Edzea ame abe 4.5 ene le ame 100,000 ɖesiaɖe me le amewo katã dome. Le kpɔɖeŋu me, le United States la, wokpɔa dɔléle sia le ame siwo ade 1,200 ŋu ƒe sia ƒe.

Zi geɖe la, ACC dzea ame siwo xɔ tso ƒe 40 va ɖo ƒe 60. Nɔnɔme sia bɔ ɖe nyɔnuwo me vie. Eyata abe alesi nàte ŋu akpɔe ene la, mebɔ boo o.

Nukae nye esia ƒe dzesiwo? Ðe esiawo hã le asinyea?

Adenoid cystic carcinoma ƒe dzesiwo toa vovo le dɔdzẽa ƒe lolome kple afisi wòle nu . Àte ŋu ato nu siwo gbɔna la me:

• Ʋuʋudedi si me vevesese aɖeke mele o le ŋutilãa ƒe teƒe aɖe.
• Yagbɔgbɔ sesẽ.
• Nu mimi sesẽ.
• Gbeɖiɖi ƒe ɖiɖi.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.
• No me ʋuʋu.
• Ʋu si dona le ŋɔti me.
• Vevesese (le go aɖewo me).
• Nukpɔkpɔ trɔna.

Gake ɖo ŋku edzi be esi wònye be ACC nye kansa si le tsitsim blewu ta la, meɖea dzesiwo fiana ɣesiaɣi o . Ate ŋu anɔ anyi gɔ̃ hã dzesi aɖeke manɔmee. Esia tae wòle vevie be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo ne ède dzesi nane si mebɔ o.

Nukatae esia dzɔna ɖo? Nukawoe nye susu siwo tae?

Ne míagblɔe tututu la, eŋutinunyalawo meka ɖe nusi tututu hea adenoid cystic carcinoma vɛ dzi haɖe o . Wosusu be ɖewohĩ domenyiŋusẽfianu ƒe tɔtrɔ aɖewo siwo dzɔna le ɣeyiɣi aɖe megbe gbɔe wòtso. Nu vevitɔe nye be ACC menye domenyiŋusẽfianu ƒe nɔnɔme o , eye womenya afɔku siwo ate ŋu ahe vɛ o. Ema fia be mehiã be nàtsi dzi ɖe "Esiae nye nusi mewɔ si he nusia vɛa?"

Nukawoe nye kuxi siwo ate ŋu ado tso ACC me?

Adenoid cystic carcinoma ate ŋu akaka (akaka) ɖe ŋutilã bliboa me le mɔ vevi eve nu. Esia nye nusi ŋu wòle be woatsi dzi ɖo.

1. Perineural invasion: Le ACC ƒe nɔnɔme geɖe me la, kansa lãmenugbagbeviwo gena ɖe lãmeka siwo ƒo xlã dɔdzẽa me. Esia dzɔna le mɔ si menya kpɔna dzea sii bɔbɔe o nu ale gbegbe be ate ŋu asesẽ na ɖɔktawo be woade dzesii, ne woɖe fotoe alo le amekoko me gɔ̃ hã.

2. Kaka to ʋukawo me: Kansa lãmenugbagbevi siwo klã tso dɔdzẽ aɖe gbɔ ate ŋu ato wò ʋukawo me ayi wò ŋutilã ƒe akpa bubuwo.

Adenoid cystic carcinoma sia ƒomevi, si nye afɔɖeɖe 4 lia , kakana ɖe lãkusi kple aklã me zi geɖe . To vovo na kansa ƒomevi bubuwo la, ƒã hafi ACC kaka ɖe ʋukawo me. Ke hã, ate ŋu adzɔ le 5% va ɖo 10% me.

Aleke wokpɔa dɔléle sia dzea sii? (Dɔléle ƒe dzesi) .

Ne wò ɖɔkta susui be adenoid cystic carcinoma ate ŋu anɔ ŋuwò la, anɔ eme be awɔ ŋutilã ƒe akpa aɖewo ɖeɖeɖa . Esia fia be nàɖe wò lãkusi sue aɖe atsɔ aɖoe ɖe dodokpɔxɔ me be woadoe kpɔ. Ðɔktaa ate ŋu awɔ nɔnɔmetatawo dodokpɔ ɖeka alo esi wu nenema hã, abe:

• CT scan (kɔmpiuta dzi tomography scans) .
• MRI (magnetic resonance imaging) ƒe nɔnɔmetata .
• PET-dɔdamɔnu (positron-emission tomography scans) .
• Ultrasound ƒe dɔwɔwɔ

Esi wònye be ACC nye dɔléle si mebɔ o ta la, ate ŋu axɔ ɣeyiɣi aɖe hafi woate ŋu akpɔe . Ate ŋu axɔ dodokpɔ zi geɖe hafi woakpɔ dɔlélea le ŋuwò eye nàdze atikewɔwɔ gɔme. Eyata ele vevie be míagbɔ dzi ɖi eye míagatsi dzodzodzoe o.

Nukawoe nye atike siwo wozãna na ACC?

Adenoid cystic carcinoma dada nɔ te ɖe afisi kansa le kple ne ekaka dzi . Atikewɔwɔ ƒe mɔnu vevi geɖewo li:

• Amekoko:Adenoid cystic carcinoma ƒe atike vevitɔe nye amekoko. Taɖodzinuae nye be woaɖe dɔdzẽa ƒe akpa gãtɔ ɖa alesi woate ŋui. Le go aɖewo me la, ahiã hã be wò amekola naɖe ʋukawo alo lãmeka aɖe ƒe akpa aɖe ɖa.
• Kekeli ƒe atikewɔwɔ: Esia kpena ɖe ame ŋu wòwua kansa lãmenugbagbevi ɖesiaɖe si susɔ le amekoko vɔ megbe. Alo, woate ŋu ana keklẽŋusẽdɔdamɔnu abe atikewɔwɔ ɖeka ene.
• Atikewɔwɔ: Wozãa atikewo abe cisplatin, vinorelbine, paclitaxel, kple carboplatin ene tsɔ daa dɔléle siwo de ŋgɔ alo esiwo kaka ɖe teƒe bubuwo (ACC).
• Atikewɔwɔ si woɖo taɖodzinu na: Atikewo abe lenvatinib kple sunitinib ene xea mɔ na protein siwo kpena ɖe kansa ŋu wòtsina ƒe dɔwɔwɔ. Ðɔktawo zãa atikewɔmɔnu siawo siwo ŋu woɖo taɖodzinu ɖo le ACC si de ŋgɔ alo esi kaka ɖe teƒe geɖe ƒe nɔnɔmewo me.

Ðe mɔ aɖe li si dzi woato axe mɔ ɖe esia nua?

Esi wònye be womenya afɔku siwo ate ŋu ahe (ACC) vɛ o ta la, mɔ aɖeke meli si dzi nàto aɖe wò afɔkua dzi akpɔtɔ fifia o . Azɔ hã, mɔ aɖeke meli si dzi woato axe mɔ na (ACC) be wòagagava o. Esia nye vevesese vie, gake aleae wòle fifia.

Nukae nye mɔkpɔkpɔ na ACC? (Nukpɔsusu) .

Adenoid cystic carcinoma nye kansa si le tsitsim blewu . Le esia ta la, zi geɖe la, ɖɔktawo te ŋu dea dzesii kaba eye wodaa dɔ nɛ dzidzedzetɔe. Ke hã, abe alesi míegblɔe va yi ene la, ebɔ be ACC gadzɔna le ƒe geɖe megbe – ateŋu anɔ teƒe si wònɔ tsã, alo ateŋu anɔ ŋutilã ƒe akpa bubu. Ne ewɔe la, edada ate ŋu asesẽ wu.

Mina míasrɔ̃ nu tso agbetsitsi ƒe agbɔsɔsɔme ŋu.

Ƒe atɔ̃ ƒe agbetsitsi ƒe agbɔsɔsɔ bliboa le amesiwo ŋu adenoid cystic carcinoma le gome nye 80.4% . Esia fia be amesiwo ŋu dɔlélea le ƒe 80.4% gakpɔtɔ le agbe le ƒe atɔ̃ megbe. Ƒe 10 ƒe agbetsitsi ƒe agbɔsɔsɔme nye 61.3% .

Ðo ŋku edzi be akɔntabubuwo koe agbetsitsi ƒe agbɔsɔsɔ siawo nye . Womegblɔa ɣeyiɣi didi si tututu nànɔ agbe alo alesi nàwɔ nui ne wowɔ atike na wò o. Anyo wu be nàƒo nu kple wò ɖɔkta hena nyatakaka bubuwo.

Aleke malé be na ɖokuinye? Susu ƒe lãmesẽ le vevie ŋutɔ!

Esi wònye be ACC nye dɔléle si mebɔ o ta la, ate ŋu axɔ ɣeyiɣi aɖe hafi woakpɔ dɔlélea. Ate ŋu akpɔ ŋusẽ ɖe wò susu kple seselelãme ƒe lãmesẽ dzi ŋutɔŋutɔ . Eyata nuƒoƒo kple aɖaŋuɖola alo atikewɔla ate ŋu akpe ɖe ŋuwò nàwɔ dɔ le seselelãme sesẽ siwo me tom nèle la me. Ame geɖe kpɔnɛ be kpekpeɖeŋunahawo kpena ɖe ame ŋu.Àte ŋu akpɔ gbɔdzɔe tso nuteɖeamedzi me to hadzidzi alo aɖaŋudɔdada ƒe hehexɔxɔ me. Dze agbagba nàɖe nuteɖeamedzi dzi akpɔtɔ to susuŋudɔwɔwɔ ƒe kamededewo, abe ŋugbledede ene, me .

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Ne adenoid cystic carcinoma le ŋuwò la, gblɔe na wò ɖɔkta enumake ne dzesi yeyewo le ŋuwò alo ne wò dzesiawo gagblẽ ɖe edzi . Dzesiwo ƒe tɔtrɔ ate ŋu afia be wò kansa la dzi ɖe edzi. Eya ta, mègaŋe aɖaba ƒu naneke dzi o, sue aɖe gɔ̃ hã.

Nya vevi kawoe wòle be míabia ɖɔktaa?

Nya aɖewo siwo nàte ŋu abia wò ɖɔkta tso ACC ŋue nye esi:

• Afikae kansa ƒe dɔdzẽa le?
• Dzesi kawoe mate ŋu akpɔ?
• Ðe kansa la kaka ɖe nye ŋutilã ƒe akpa bubuwoa?
• Ðe woate ŋu aɖe dɔdzẽa ɖa to amekoko mea?
• Ðe mahiã be woatsɔ keklẽŋusẽ awɔ dɔea?
• Ðe mate ŋu ayi dɔme esime mele kansadɔ dama?
• Ɣeyiɣi didi kae atikewɔwɔa xɔa?

Mègavɔ̃ gbeɖe be yeabia nya siawo tɔgbe o. Ele vevie ŋutɔ be nàƒo nu kple wò ɖɔkta tso nusianu si le susu me na wò ŋu.

Mlɔeba la, nusiwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Adenoid cystic carcinoma ƒe dzesi xɔxɔ nye nudzɔdzɔ si trɔa ame ƒe agbenɔnɔ. Zi geɖe la, atikewɔwɔ kaba kpɔa dzidzedze . Ke hã, kakaɖedzimanɔamesi si dona tso eme la gbɔ kpɔkpɔ ate ŋu asesẽ. Agbenɔnɔ kple adenoid cystic carcinoma sɔsrɔ̃ xɔa ɣeyiɣi.

Nu vevitɔ kekeakee nye be nànya be menye wò ɖeka koe o. Bu eŋu kpɔ be yeage ɖe kpekpeɖeŋunaha aɖe si me nàte ŋu aƒo nu kple ame siwo to nɔnɔme mawo ke me abe wò ene me. Wò ɖɔkta nɔa gbɔwò ɣesiaɣi. Ka ɖe wo dzi eye nàbia nunɔamesiwo kple kpekpeɖeŋu siwo nèhiã. Ne èdoa wò kpɔ edziedzi eye nèwɔna ɖe woƒe aɖaŋuɖoɖowo dzi la, àte ŋu ayi ŋgɔ le nɔnɔme sia me dzidzedzetɔe.

` Adenoid cystic carcinoma, ACC, kansa, ta kple kɔ me kansa, aɖuɖɔtoe me kansa, kansa ƒe dzesiwo, kansa dada