Numeɖeɖe bɔbɔe si ku ɖe ƒunukpeƒetetedɔ wɔnuku siwo le afɔwo kple abɔwo ŋu ŋu: Mina míasrɔ̃ nu tso Clear Cell Sarcoma ŋu.

Ðe ƒunukpeƒetetedɔ alo tsitsi aɖe si mebɔ o va le wò afɔ alo alɔnu ƒe ŋutigbalẽ te si madzo o kpɔa? Ðewohĩ mavee gɔ̃ hã ne èzi edzi o. Gake ne ese le eɖokui me be ele gã dom ɖe edzi la, ate ŋu anye nusi ŋu wòle be woatsi dzi ɖo. Egbea míele nu ƒom tso kansa si mebɔ o si ate ŋu ahe dzesi mawo tɔgbe vɛ ŋu, gake enyo be míanya. Woyɔe be Clear Cell Sarcoma .

Nukae Nye Clear Cell Sarcoma?

Kpuie ko la, lãmenugbagbevi siwo me kɔ ƒe sarcoma nye kansa ƒomevi aɖe si mebɔ kura o, si dzɔna le lãmeka falɛfalɛwo me . Edze le hatsotso aɖe si woyɔna be sarcoma me . Zi geɖe la, kansa siawo dzea egɔme tso lãkusiwo me , siwo nye lãkusi siwo doa ka kple lãmekawo kple ƒuwo, kple lãkusi falɛfalɛ siwo ƒo xlã lãmekawo, le wò afɔwo me, vevietɔ le wò afɔwo me.

Abe kansa ƒomevi bubuwo ene la, lãmenugbagbevi siwo me kɔ ƒe sarcoma dada le bɔbɔe wu ne wokpɔe hafi wòkaka ɖe ŋutilã ƒe akpa bubuwo. Ðɔktawo daa dɔléle sia koŋ to amekoko me , eye ne ehiã la , wozãa keklẽŋusẽdɔdamɔnu kple ɣeaɖewoɣi atikewɔmɔnu . Nublanuitɔe la, le atikewɔwɔ vɔ megbe gɔ̃ hã la, mɔnukpɔkpɔ geɖe li be dɔlélea nagadzɔ ake. Esia tae atikewɔwɔ ŋuti numekulawo le mɔnu yeye siwo dzi woato ada lãmenugbagbevi siwo me kɔ ƒe sarcoma dim ɣesiaɣi ɖo.

Aleke lãmenugbagbevi siwo me kɔ ƒe sarcoma kpɔa ŋusẽ ɖe nye ŋutilã dzii?

Zi geɖe la, lãmenugbagbevi siwo me kɔ ƒe sarcoma dzea egɔme tso lãkusi falɛfalɛ goglo siwo ƒo xlã wò lãkusiwo kple lãmekawo me, alo le lãkusi aɖe si woyɔna be fascia me. Fascia le abe haƒonu si xatsa ɖe míaƒe ŋutilã ƒe wɔwɔme ɖesiaɖe ŋu ene.

Gbã la, ɖewohĩ màde dzesi naneke o. Gake àde dzesii ne kansa la tsi eye wòzu ƒuƒu si woate ŋu ase le wò afɔ alo afɔ ƒe ŋutigbalẽ te. Kpe sia adze abe ƒunukpeƒetetedɔ si dona ne èƒo wò afɔ alo afɔ sesĩe ene, gake vovototo vevitɔe nye be ƒunukpeƒe sia metsina le ɣeyiɣi aɖe megbe o . Lãmenugbagbevi siwo me kɔ ƒe sarcoma tsina blewu ŋutɔ. Gake kaka wòakaka tso wò lãmeka falɛfalɛ goglo siwo le ŋutigbalẽa te me la, ɖewohĩ edze kaka ɖe wò ŋutilã ƒe akpa bubuwo xoxo.

Bu eŋu kpɔ, èxɔ ƒoƒo sue aɖe le wò afɔ ŋu eye nèŋe aɖaba ƒu edzi, henɔ susum be, "Oo, ɖeko esia anya dzɔ teti koe nye ema." Kwasiɖa alo ɣleti aɖewo megbe la, egakpɔtɔ li, ɖewohĩ elolo vie gɔ̃ hã. Le nɔnɔme ma me la, anyo wu godoo be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Afikae lãmenugbagbevi siwo me kɔ ƒe sarcoma kaka ɖo?

Lãmenugbagbevi siwo me kɔ ƒe sarcoma ate ŋu akaka ɖe ŋutilã ƒe akpa bubuwo, vevietɔ:

• Wò nuɖuɖumeŋusẽ (dɔgbome) .
• Wò tɔeNa lãkusiwo
• Wò ʋukawo , si nye ʋuka siwo me ʋu sina tona kple ʋuka siwo le wò ŋutilã me.

Ðe esia nye nɔnɔme si bɔa?

Ao, menye nenema kura o. Esia nye kansa ƒomevi sue aɖe si mebɔ kura o. Le nyateƒe me la, sarcoma hã nye kansa ƒomevi aɖe si mebɔ o. Le kpɔɖeŋu me, le United States la, wokpɔa sarcoma le ame siwo ade 1,600 ŋu ƒe sia ƒe. Ema nye xexlẽme sue aɖe, si ade 1% le kansa siwo katã le ame tsitsiwo me la me. Clear cell sarcoma, ema nye 1% ko le sarcoma katã me. Eyata àte ŋu akpɔ alesi gbegbe esia mebɔ o la le susu me.

Amekae ate ŋu axɔ lãmenugbagbeviwo ƒe sarcoma si me kɔ wu?

Togbɔ be lãmenugbagbeviwo ƒe sarcoma si me kɔ ate ŋu adze le ƒe ɖesiaɖe me hã la, sɔhɛ siwo xɔ tso ƒe 15 va ɖo ƒe 40 , vevietɔ esiwo xɔ ƒe 20 va ɖo ƒe 30 ye wokpɔnɛ zi geɖe.

Nukae nye lãmenugbagbevi siwo me kɔ ƒe sarcoma ƒe dzesiwo?

Abe alesi míeƒo nu tso eŋu va yi ene la, dzesi si bɔ wue nye ƒu si medzona le wò afɔ alo afɔ ƒe ŋutigbalẽ te o . Kpe sia ate ŋu ave ame alo mavee o. Gake ne ele afima eye wòse le eɖokui me be ele gã dom ɖe edzi la, ke dzesi vevi aɖee nye ema.

Tsɔ kpe ɖe eŋu la, dzesi siwo gbɔna ate ŋu adze emegbe:

• Ðeɖiteameŋu si gbɔ eme le susu aɖeke manɔmee
• Kpekpeme dzi ɖeɖe kpɔtɔ si womeɖe o
• Zã me fifia

Nukae hea lãmenugbagbevi siwo me kɔ ƒe sarcoma vɛ?

Esia sesẽ vie. Atikewɔwɔ ŋuti numekulawo kpɔe be lãmenugbagbevi siwo me kɔ ƒe sarcoma tsoa domenyiŋusẽfianu eve siwo le míaƒe ŋutilã me lãmenugbagbeviwo me ƒe akpa aɖewo ƒe teƒewo ɖɔliɖɔli, si wɔnɛ be domenyiŋusẽfianu yeye si wotsɔ tsaka vɛ .

Kpuie ko la, nusi dzɔnae nye esi:

Ne míaƒe ŋutilã ƒe lãmenugbagbeviwo ma la, ɣeaɖewoɣi la, domenyiŋusẽfianu eve gbãna eye kakɛ siwo gbã la ɖɔlia wo nɔewo. Le go sia me la, domenyiŋusẽfianu siwo woyɔna be EWSR1 kple ATF1 le domenyiŋusẽfianu ƒe akpa siwo woɖɔlia wo nɔewo me. Edze abe protein si EWSR1 domenyiŋusẽfianu wɔna la le vevie na lãmenugbagbeviwo ƒe dɔwɔwɔ ene. ATF1 domenyiŋusẽfianu kpena ɖe ame ŋu wòkpɔa lãmenugbagbeviwo ƒe tsitsi dzi. Ne domenyiŋusẽfianu siawo gaƒo ƒu la, domenyiŋusẽfianu ƒe akpa siwo woɖɔli la va wu enu ɖe ​​teƒe siwo mesɔ o. Ðɔktawo yɔa esia be tɔtrɔ ɖe wo nɔewo ŋu . Womenya susu si tututu tae esia dzɔna ɖo haɖe o.

Ne wonya tsɔe yi domenyiŋusẽfianu yeye aɖe me ko la, domenyiŋusẽfianu siwo woɖɔli la va ƒoa ƒu wɔa domenyiŋusẽfianu si wotsɔ tsaka si woyɔna be EWSR1/ATF1 . Numekulawo xɔe se be domenyiŋusẽfianu sia si wotsɔ tsakae koŋue hea lãmenugbagbevi siwo me kɔ ƒe sarcoma vɛ.

Aleke ɖɔktawo wɔa dea dzesi lãmenugbagbevi siwo me kɔ ƒe sarcoma?

Ne èyi ɖɔkta si ŋu ƒunukpeƒetetedɔ ma tɔgbe le gbɔ la, ado wò kpɔ gbã eye wòalé ŋku ɖe afi si ƒunukpeƒea le, eƒe lolome, kple nu bubuwo ŋu. Emegbe ɖewohĩ ahiã be woawɔ MRI-dɔdamɔnu (Magnetic Resonance Imaging - MRI).Ate ŋu adzɔ.

Gake woɖo kpe lãmenugbagbevi siwo me kɔ ƒe sarcoma ƒe dzesi dzi to ŋutilã ƒe akpa aɖe ɖeɖeɖa me, si bia be woaɖe lãkusi sue aɖe tso ƒunukpeƒea me . Ne wodo lãmenugbagbeviwo ƒe kpɔɖeŋu sia kpɔ le nusuekpɔmɔ̃ me la, dɔléleŋutinunyalawo, siwo nye eŋutinunyala bibi siwo doa lãmenugbagbeviwo kpɔ le dodokpɔxɔ me la, dia domenyiŋusẽfianu si wotsɔ tsaka si nye EWSR1/ATF1 si ŋu míeƒo nu tsoe va yi la ƒe anyinɔnɔ.

Aleke wodaa lãmenugbagbevi siwo me kɔ ƒe sarcoma?

Ðɔktawo ƒe taɖodzinu vevitɔe nye be yewoaxe mɔ na lãmenugbagbevi siwo me kɔ ƒe sarcoma be wòagakaka ɖe ŋutilã ƒe akpa bubuwo o. Zi geɖe la, afɔɖeɖe gbãtɔe nye be woawɔ dɔ nɛ be woaɖe dɔdzẽa ɖa keŋkeŋ . Ne kansa la kaka ɖe ʋukawo me la, woɖea ʋuka mawo hã ɖa. Esia kplɔe ɖo kple atikewɔwɔ si kpena ɖe ame ŋu . Zi geɖe la, esia bia be woatsɔ keklẽŋusẽ awɔ dɔe be woatsɔ awu kansadɔlékui ɖesiaɖe si susɔ.

Atikewɔwɔ ŋuti numekulawo le numekuku wɔm tso atikewɔmɔnu bubuwo ŋu fifia. Le kpɔɖeŋu me, wole ŋku lém ɖe alesi dɔlélenutsiŋutete ƒe atikewɔwɔ wɔa dɔ nyuie le lãmenugbagbevi siwo me kɔ ƒe sarcoma dzi ɖuɖu me ŋu. Wole edom kpɔ hã be atike siwo wozãna fifia tsɔ daa kansa ƒomevi bubuwo ate ŋu akpe ɖe ame ŋu wòatɔ te lãmenugbagbevi siwo me kɔ ƒe sarcoma ƒe kaka hã.

Nu vevitɔe nye be lãmenugbagbevi siwo me kɔ ƒe sarcoma nye nɔnɔme si ate ŋu agadzɔ zi geɖe. Ne edzɔ alea la, ɖewohĩ ahiã be woawɔ dɔ na wò geɖe wu eye woawɔ keklẽŋusẽdɔdamɔnu geɖe na wò. Eye esi wònye be ate ŋu akaka kabakaba ŋutɔ ta la, ɖɔktawo alé ŋku ɖe ŋuwò edziedzi akpɔe ɖa be dɔdzẽ yeyewo do mo ɖa hã.

Ðe mate ŋu aɖe afɔku si le lãmenugbagbevi siwo me kɔ ƒe sarcoma xɔxɔ me dzi akpɔtɔa?

Nublanuitɔe la, naneke meli nàte ŋu awɔ atsɔ aɖe dɔléle sia xɔxɔ ƒe afɔkua dzi akpɔtɔ o. Elabena atikewɔwɔ ŋuti numekulawo mekpɔ de dzesi afɔku aɖeke koŋ si ana woaxɔ lãmenugbagbevi siwo me kɔ ƒe sarcoma o. Afɔku nye nuwɔna alo nɔnɔme aɖe si nana dɔléle aɖe xɔxɔ ƒe mɔnukpɔkpɔ dzina ɖe edzi.

Ðe woate ŋu ada lãmenugbagbevi siwo me kɔ ƒe sarcoma keŋkeŋa?

Ðɔktawo ate ŋu ada clear cell sarcoma, si fia be woate ŋu aɖe dɔdzẽa ɖa ahadze agbagba be yewoaɖu eƒe kaka dzi. Gake menye nɔnɔme si woate ŋu ada keŋkeŋ o . Zi geɖe la, lãmenugbagbevi siwo me kɔ ƒe sarcoma ate ŋu akaka ɖe ŋutilã ƒe akpa bubuwo hafi woakpɔe. Esia wɔnɛ be edada sesẽna ɖe edzi. Anɔ eme hã be wòagatrɔ ava le atikewɔwɔ vɔ megbe.

Nukae nye agbenɔƒe si amesi ŋu lãmenugbagbevi siwo me kɔ ƒe sarcoma le?

Agbenɔƒe nye ɣeyiɣi didi si nànɔ agbe ƒe akɔntabubu si wotu ɖe wò lãmesẽ bliboa kple wò ŋutɔ wò nɔnɔmewo dzi. United States Dukɔa ƒe Kansa Ŋuti Nyatakakadzraɖoƒe ƒe numekuku aɖe si wowɔ le ƒe 2018 me ɖee fia be le amesiwo ŋu lãmenugbagbevi siwo me kɔ nyuie ƒe sarcoma le dome la, .Egblɔ hã be 50% gakpɔtɔ le agbe ƒe atɔ̃ le dɔlélea kpɔkpɔ vɔ megbe, eye 38% gakpɔtɔ nɔ agbe ƒe ewo le dɔlélea kpɔkpɔ vɔ megbe .

Míeɖaƒo nu tso agbenɔƒe alo agbetsitsi ƒe agbɔsɔsɔme ŋu o, ele vevie be míaɖo ŋku edzi be akɔntabubuwo koe esiawo nye, ke menye nyagblɔɖiwo o. Agbenɔƒe ƒe didime nye akɔntabubu si wotu ɖe amewo katã dzi. Wonɔa te ɖe ɣeyiɣi didi si amewo nɔa agbe le kansa ƒomevi aɖe koŋ dada vɔ megbe dzi. Nu geɖe li siwo ate ŋu akpɔ ŋusẽ ɖe ame ƒe agbenɔƒe alo mɔnukpɔkpɔ si li be wòatsi agbe le kansa me dzi. Ne lãmenugbagbeviwo ƒe sarcoma si me kɔ le ŋuwò la, wò ɖɔkta ate ŋu ana nyatakaka nyuitɔ kekeake wò tso nusi nàkpɔ mɔ na ŋu.

Ðe lãmenugbagbevi siwo me kɔ ƒe sarcoma ate ŋu awu amea?

Ẽ, ate ŋu awu ame. Le goawo katã me la, amesiwo ƒe lãmenugbagbevi siwo me kɔ nyuie ƒe sarcoma kaka ɖe ŋutilã ƒe akpa bubuwo la kuna kaba wu amesiwo wowɔ atike na hafi kansa la kaka.

Ɣekaɣie wòle be makpɔ nye ɖɔkta?

Esi wònye be lãmenugbagbevi siwo me kɔ ƒe sarcoma ate ŋu agadzɔ le atikewɔwɔ vɔ megbe ta la, wò ɖɔkta adi be yeakpɔ wò ɣleti etɔ̃ ɖesiaɖe le ƒe eve gbãtɔ siwo le atikewɔwɔ vɔ megbe, le wò nɔnɔmea nu. Ele vevie be woado wo kpɔ edziedzi le ɣeyiɣi aɖewo megbe le ema megbe.

Nya kawoe wòle be mabia nye ɖɔkta?

Clear cell sarcoma nye dɔléle si mebɔ kura o. Ate ŋu ade ame ƒe agbe afɔku me. Ne wokpɔ dɔléle sia le ŋuwò la, àte ŋu abia nya siawo wò ɖɔkta:

• Afikae dɔdzẽa le? Aleke gbegbee wòloloe?
• Ðe dɔdzẽa kaka ɖe nye ŋutilã ƒe teƒe bubu aɖea?
• Atikewɔwɔ kawoe nèkafu?
• Nukawoe nye atikewɔwɔa ƒe nugbegblẽ le ame ŋu?
• Ne wowɔ dɔ nam la, mɔnukpɔkpɔ kawoe li be dɔdzẽa nagatrɔ ava?
• Ðe dɔdamɔnu dodokpɔ aɖewo li siwo ŋu mate ŋu abua?

Kpuie Kpuie Kple Gbedasi si Wotsɔ Yi Aƒeme

Clear Cell Sarcoma nye dɔléle sesẽ ŋutɔŋutɔ. Ƒã ŋutɔ. Ame ʋɛ aɖewo koe wògblẽa nu le le ƒe ɖeka me. Eye wòtsina blewu ŋutɔ. Sarcoma ate ŋu akaka eye wòawu ame hafi ame akpa gãtɔ nade dzesi tɔtrɔwo le woƒe ŋutilã me.

Gake ɖo ŋku edzi be ɖɔktawo ate ŋu ada lãmenugbagbevi siwo me kɔ ƒe sarcoma. Woate ŋu aɖe dɔdzẽa ɖa to amekoko me, eye woate ŋu ana atike wò hã be nàwu kansadɔlékui ɖesiaɖe si susɔ. Nublanuitɔe la, zi geɖe la, lãmenugbagbevi siwo me kɔ ƒe sarcoma ate ŋu atrɔ ava. Eyata ele vevie be nàdo wò ŋutilã kpɔ edziedzi eye nànya tɔtrɔ ɖesiaɖe si ava wò ŋutilã me.

Atikewɔwɔ ŋuti numekulawo le mɔ yeye siwo dzi woato ada lãmenugbagbevi siwo me kɔ ƒe sarcoma dim. Ne lãmenugbagbeviwo ƒe sarcoma si me kɔ le ŋuwò la, woate ŋu awɔ dɔdamɔnu dodokpɔ yeyewo.Ne èdi be yeanya nu geɖe tso eŋu la, bia wò ɖɔkta tso eŋu eye nàxɔ aɖaŋuɖoɖo. Mègana mɔkpɔkpɔ gbeɖe o. Ne èna atikewɔlawo ƒe aɖaŋuɖoɖo kple kpekpeɖeŋu nyuitɔ la, àte ŋu adze ŋgɔ kuxi sia.

` clear cell sarcoma, falɛfalɛ ƒe kansa, afɔ ƒe dɔdzẽ, afɔ ƒe dɔdzẽ, sarcoma, kansa ƒe dzesiwo, kansa dada