Ðe aɖuɖɔtoe le viwò suea ŋu ŋkeke ʋɛ aɖewoe nye esia? Vidada kple vifofo ɖesiaɖe avɔ̃ ne wokpɔ ʋu vi aɖe le woƒe aɖuɖɔ mea? Zi geɖe la, wosusuna be enye dɔgbo ƒe vevesese dzro aɖe ko, gake ɣeaɖewoɣi la, ate ŋu anye nɔnɔme si nu sẽ wu ƒe dzesi gbãtɔ. Emae nye nusi ŋu míele nu ƒom tsoe egbea, Hemolytic Uremic Syndrome, alo HUS kpuie, si nye nɔnɔme sesẽ aɖe si ate ŋu adzɔ, vevietɔ le dɔlékui si nye E. coli ƒe dɔlékui xɔxɔ vɔ megbe. Mina míasrɔ̃ nu tso esia ŋu bɔbɔe eye wòade pɛpɛpɛ.
Kpuie ko la, nukae nye HUS?
Bu ʋuka siwo le míaƒe ŋutilã katã me be wonye mɔdodowo ƒe ƒuƒoƒo. Mɔ siawo dzie míaƒe ʋumenugbagbevi dzĩwo tsɔa ɔksidzin yia ŋutilã bliboa me le. Le nɔnɔme aɖe si woyɔna be HUS me la, ʋukawo dzɔna eye woxena ɖe ʋuka suesuesuewo (capillaries) me, vevietɔ le ayikuwo me . Ele abe tsi ƒe pɔmpi si me ɖi kple tsi xɔ aƒe ɖo ene.
Ne ʋukawo xe mɔ sia la, nu vevi etɔ̃ dzɔna:
1. Hemolytic Anemia: Ʋumenugbagbevi dzĩ siwo dzea agbagba be yewoato ʋuka siwo xe me la tsia, wogbãna, eye wogbãna. Esia wɔnɛ be ʋu ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna le ŋutilãa me, si fia be ʋusɔgbɔdɔ.
2. Ʋumenugbagbevi dzĩwo ƒe xexlẽme dzi ɖena kpɔtɔna (Thrombocytopenia): Lãmenugbagbevi sue siawo siwo kpena ɖe ʋu ƒe sisi ŋu la zãna le ʋumenugbagbeviɣi siwo dzɔna le ʋukawo me la me. Esia wɔnɛ be ʋumenugbagbevi dzĩ siwo le ʋua me ƒe xexlẽme si sɔ dzi ɖena kpɔtɔna.
3. Ayikuwo ƒe Dɔmawɔmawɔ nyuie: Esi ayikuwo mexɔa ʋu si sɔ o eye ʋukawo hã gblẽ ta la, ayikuawo mete ŋu ɖea gbeɖuɖɔwo ɖa le míaƒe ŋutilã me nyuie heɖea wo ɖa abe aɖuɖɔ ene o. Esia ate ŋu ana ayiku nawɔ dɔ kpata.
Togbɔ be nɔnɔme sia ate ŋu adzɔ le ƒe ɖesiaɖe me hã la, ɖevi siwo mexɔ ƒe 5 haɖe o ŋue wòbɔ ɖo wu. Eyata ne viwòa le ʋu ɖum la, mègaŋe aɖaba ƒu edzi gbeɖe o.
Nuka koŋue hea HUS vɛ?
Zi geɖe la, abe ɣeyiɣi 90% ene la, dɔlékui aɖe si woyɔna be E. coli (Escherichia coli) ye hea HUS vɛ, si wɔa aɖi aɖe si woyɔna be Shiga toxin . Dɔlékui sia toa nuɖuɖu ƒoɖi siwo meɖa nyuie o alo tsi si me dɔlékui le me gena ɖe míaƒe ŋutilã me.
Bu nɔnɔme sia ŋu kpɔ. Èle nu ɖum le nuɖuɖudzraƒe aɖe kple wò ƒomea. Ne èɖu nyilã si womeɖa nyuie o (vevietɔ nyilã si wotu), notsi alo cheese si wometsɔ dɔlékuiwutike wɔe o, alo sabala alo amagbe siwo womeklɔ o la, E. coli dɔlékui ate ŋu anɔ eme.
Ne dɔlékui sia ge ɖe ŋutilãa me la, enaa dɔgbo vea ame eye wònana ame ƒe aɖuɖɔtoe si me tsi le le ŋkeke ʋɛ aɖewo ko me. Le ŋkeke ɖeka alo eve me la, esia va zua aɖuɖɔtoe si me ʋu le.Shiga aɖi siwo dɔlékuiawo wɔna gblẽa nu le míaƒe dɔgbo ƒe gliwo ŋu eye wònana ʋu dona. Emegbe aɖi siawo gena ɖe ʋukawo me hezɔna toa ŋutilã bliboa me, eye wogblẽa nu le ʋuka sue siwo le ayikuawo me ŋu. Aleae HUS dzea egɔmee.
Ðe HUS ƒomevi vevi aɖewo lia?
Ẽ, woate ŋu ama HUS ɖe hatsotso vevi geɖe me.
- "Typical" HUS: Esia nye ƒomevi si ŋu míeƒo nu tsoe vaseɖe fifia, si tso dɔlékui ƒe dɔléle abe E. coli ene gbɔ wu.
- Atypical HUS (aHUS): Esia nye ƒomevi si mebɔ o. Domenyiŋusẽfianu ƒe gbɔdzɔgbɔdzɔ aɖe gbɔe wòtsona. Esia fia be woate ŋu anyie ƒe dome tso dzilawo gbɔ na ɖeviwo. Ame siawo ate ŋu axɔ HUS kpata, ne nane abe dzamezã alo dzamezã ene le wo ŋu gɔ̃ hã.
- HUS evelia: Esia dzɔna abe atikewɔwɔ ƒe nɔnɔme bubu (e.g. kansa) alo atike aɖewo (e.g. atike siwo tsia kansa nu, dɔlélenutsiŋutete ƒe atikewo) ƒe nugbegblẽ le ame ŋu ene.
Nukae nye HUS ƒe dzesiwo? Aleke wokpɔa dɔlélea dzea sii?
Zi geɖe la, HUS ƒe dzesiwo dzena le akpa eve me. Gbã la, dzesi siwo do ƒome kple dɔgbo ƒe dɔlélea dzena. Emegbe, dzesi siwo nu sẽ wu siwo do ƒome kple HUS la dzena.
| Dzesi siwo dzena le gɔmedzedzea me (siwo do ƒome kple dɔlékuiwo xɔxɔ) . | Dzesi siwo dzena le eƒe nuwuwu (si do ƒome kple HUS) . |
|---|---|
| Dɔgbo ƒe vevesese sesẽ | Paleness (le ʋusɔgbɔdɔ ta) . |
| Aɖuɖɔtoe kple ʋuʋudedi | Ðeɖiteameŋu si gbɔ eme kple alɔ̃dɔdɔ |
| Aɖuɖɔtoe si me tsi le, emegbe aɖuɖɔtoe si me ʋu le | Abi bɔbɔe (teƒe siwo le blɔ) . |
| Asrã kple vuvɔ | Aɖuɖɔ si dona le lãme na ame dzi ɖe kpɔtɔ ŋutɔ alo megale dodom o |
| Taɖuame | Ʋu si le aɖuɖɔ me (amadede dzĩ/blɔ) . |
| Afɔ, afɔkpodzi, kple mo ƒe vuvu (edema). | |
| Ʋu ƒe Ʋuʋudedi | |
| Alɔ̃madɔmadɔ alo ame ƒe susu ƒe dɔwɔwɔ |
Ɣekaɣie wòle be nàyi ɖɔkta gbɔ enumake?
Ne dzesi siawo le ŋuwò alo viwòa ŋu la, ele be nàyi kɔdzi ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU) kaba .
- Aɖuɖɔtoe si nɔa anyi wu ŋkeke etɔ̃.
- Aɖuɖɔtoe si me ʋu le.
- Ne aɖuɖɔ si nètona dzi ɖe kpɔtɔ ŋutɔ.
- Ne ɖevia ƒe mo biã eye ɖeɖi te eŋu akpa.
- Ne ŋutilãa vuvu.
Aleke ɖɔktawo ɖoa kpe HUS ƒe nɔnɔme dzi?
Ðɔkta si ado wò kpɔ la aɖo to wò dzesiwo nyuie eye emegbe wòaɖe gbe be woawɔ dodokpɔ geɖe atsɔ aɖo kpe edzi be HUS le ŋuwò.
- Ʋudodokpɔ: Esiawo ate ŋu akpɔe ɖa be ʋumenugbagbevi dzĩwo kple ʋumenugbagbevi dzĩwo ƒe xexlẽme le ʋɛ hã, eye ayiku ƒe dɔwɔwɔ (creatinine, urea, kple bubuawo).
- Aɖuɖɔtoe me dzodzro: Eléa ŋku ɖe ʋu alo protein si le aɖuɖɔ me ŋu.
- Aɖuɖɔ dodokpɔ: Eléa ŋku ɖe dɔlékuiwo abe E. coli O157 ene le aɖuɖɔ me ŋu.
- Ayiku me Dzodzro: Ɣeaɖewoɣi la, ahiã be woaɖe ayiku ƒe akpa sue aɖe ŋutɔ eye woadoe kpɔ atsɔ aɖo kpe dɔlélea dzi.
Nukawoe nye atike siwo wozãna na HUS?
HUS nye dɔléle si hiã be woaxɔ ame ɖe kɔdzi . Womate ŋu adae le aƒeme o. Esiawoe nye atike vevi siwo wowɔna le kɔdzi.
1. Na dze kple nunyiame: Aɖuɖɔtoe kple ʋuʋudedi ate ŋu ana tsi nagbɔdzɔ to tsi kple dze ɖeɖeɖa le ŋutilãa me me. Be woaxe mɔ ɖe esia nu la, wonaa saline (IV tsiwo) to ʋuka aɖe me. Ne mète ŋu ɖua nu o la, wotsɔa nunyiame naa wò to mɔ̃ aɖe dzi.
2. Ʋu kple ʋumenugbagbevi dzĩwo dodo:Wodoa ʋu ne ʋumenugbagbevi dzĩwo ƒe xexlẽme le sue akpa (ʋusɔgbɔdɔ). Wonaa ʋumenugbagbevi dzĩwo hã ne ʋumenugbagbevi dzĩwo ƒe xexlẽme le sue akpa eye ʋu ƒe dodo ƒe afɔku le eme.
3. Dialysis: Ne ayikuawo gbɔdzɔ akpa be woate ŋu aɖe gbeɖuɖɔwo ɖa le ŋutilãa me la, ehiã be woawɔ dialysis, si nye mɔ̃ si kɔa ʋua ŋu. Zi geɖe la, esia nyea ɣeyiɣi kpui aɖe ƒe dɔwɔwɔ. Woate ŋu atɔ te ʋumenugbagbeviɣidɔ ne ayikuawo gadze dɔwɔwɔ gɔme ake.
4. Atike tɔxɛwo: Le atike ƒomevi siwo mebɔ o abe atypical HUS (aHUS) ene gome la, wozãa atike tɔxɛwo abe eculizumab alo ravulizumab ene.
Vevietɔ la, numekuku aɖewo ɖee fia be dɔlékuiwutikewo alo atike siwo wua aɖuɖɔtoe nana aɖuɖɔtoe si E. coli dɔlékui hena vɛ ate ŋu ana HUS xɔxɔ ƒe afɔkua nadzi ɖe edzi . Eyata mègawɔ atike na ɖokuiwò gbeɖe ne mèyi ɖɔkta gbɔ o.
Nukae wòle be míawɔ be míaƒo asa na HUS?
Mɔ nyuitɔ si dzi míato axe mɔ ɖe HUS nu enye be míalé be na nu suesuesue siwo le míaƒe gbesiagbegbenɔnɔ me.
- Kpɔ egbɔ be yetsɔ adzalẽ klɔ asi nyuie hafi nàɖa nuɖuɖu kple le nugododeƒe zazã vɔ megbe.
- Miɖa lã, tɔmelã, kple azi nyuie. Miɖa lã ƒuƒu, vevietɔ lã ƒuƒu, vaseɖe esime wòaɖa nyuie le eme.
- Klɔ amagbe ƒuƒu, atikutsetse, kple sabala nyuie kple tsi dzadzɛ.
- Ƒo asa na notsi si wometsɔ dɔlékuiwutike o/notsi ƒuƒu, nyinotsibabla, kple atikutsetsewo nono.
- Mègazã lãtsonu, hɛ, alo nu bubu siwo wozãna tsɔ wɔa lã ƒuƒu alo tɔmelã tsɔ wɔa nuɖuɖu si woɖa o. Klɔ wo eye nàkɔ wo ŋu nyuie le wo zazã vɔ megbe.
- Ƒo asa na tsiƒuƒu le tsita ƒoɖiwo, tɔsisiwo, kple tɔʋuwo me.
- Ne aɖuɖɔtoe le ŋuwò la, ƒo asa na tsiƒuƒewo yiyi.
HUS nye nɔnɔme dziŋɔ aɖe. Gake ne wokpɔ dɔlélea kaba, wodae eye wodae kaba la, ame siwo wu 85% hayana keŋkeŋ . Zi geɖe la, nusiwo gblẽna le ayikuwo ŋu nyea ɣeyiɣi kpui aɖe ko. Eyata nu vevitɔ kekeakee nye be nànya dzesiawo eye nàdi atikewɔlawo ƒe aɖaŋuɖoɖo kaba ale si nàte ŋui.
Gbedasi si Wotsɔ Yi Aƒeme
- Hemolytic Uremic Syndrome (HUS) nye dɔléle sesẽ aɖe si gblẽa nu le ayikuwo ŋu koŋ.
- Zi geɖe la, nɔnɔme sia dzɔna le aɖuɖɔtoe si dɔlékui aɖe si woyɔna be E. coli hena vɛ megbe.
- Aɖuɖɔtoe si me ʋu le, ɣie si gbɔ eme, aɖuɖɔ si dona le lãme na ame dzi ɖena kpɔtɔna, eye wòvuvuHUS ƒe nuxlɔ̃amedzesi veviwoe nye:
- Ne dzesi siawo do mo ɖa la, kplɔ ɖevia alo dɔnɔa yi kɔdzi enumake heheɖemegbe manɔmee.
- Ne wowɔ atike na ame geɖe le kɔdzi le ɣeyiɣi nyuitɔ dzi la, wohayana bliboe.
- Nuɖuɖu kple ame ŋutɔ ƒe dzadzɛnyenye dzi kpɔkpɔ ate ŋu akpe ɖe ame ŋu be woaxe mɔ ɖe E. coli dɔlékui si hea HUS vɛ nu.
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