Ðe nèsena le ɖokuiwò me zi geɖe be yegbɔdzɔ eye yeƒe ƒuwo le veve sema? Alo ɖe wò ɖɔkta lé ŋku ɖe ʋu ƒe nyatakaka aɖe ŋu hegblɔ be, "Wò calcium ƒe agbɔsɔsɔ sɔ gbɔ vie"? Ðewohĩ susu si tae esia dzɔ ɖoe nye nɔnɔme aɖe si ŋu míeƒoa nu tsoe fũ o, gake ele vevie ŋutɔ. Egbea, mina míaƒo nu tso nɔnɔme sia si woyɔna be hyperparathyroidism ŋu le mɔ bɔbɔe aɖe si gɔme nàte ŋu ase nu.
Nukae nye hyperparathyroidism?
Kpuie ko la, hyperparathyroidism nye ne wò parathyroid gland ɖeka alo esi wu nenema va le dɔ wɔm akpa eye wòwɔ parathyroid hormone (PTH) fũ akpa. Esia wɔnɛ be calcium ƒe agbɔsɔsɔ si le wò ʋu me dzina ɖe edzi. Míeyɔa esia le atikewɔwɔ me be hypercalcemia .
Bu eŋu kpɔ, le lãkusi si le míaƒe kɔ me megbe la, lãkusi sue ene siwo lolo abe bliku ɖeka ene. Woyɔa esiawo be parathyroid glands. Abe alesi bɔl si kpɔa tsi ƒe agbɔsɔsɔ dzi le míaƒe tsigoe me le aƒeme ene la, dɔ vevitɔ si lãkusi siawo wɔnae nye be woakpɔ calcium kple phosphate ƒe agbɔsɔsɔ si le míaƒe ʋu me dzi le agbɔsɔsɔ si sɔ me.
Aleae wòwɔa dɔe nye esi:
- Ne calcium ƒe agbɔsɔsɔ le ʋua me ɖiɖi la, lãkusi siawo wɔa lãmetsi si nye PTH.
- PTH lãmetsi sia ɖoa dzesi ɖe míaƒe ƒuwo be "woaɖe calcium aɖewo ɖe ʋua me."
- Egblɔna na ayikuwo hã be "woaɖe calcium si dona le aɖuɖɔ me dzi akpɔtɔ eye wòana wòanɔ ŋutilãa me."
- Emegbe, ayikuawo naa vitamin D wɔa dɔ eye woɖonɛ ɖe míaƒe dɔgbowo me . Emegbe, dɔgboa xɔa calcium si le nuɖuɖu si míeɖuna me nyuie.
Esia nye ɖoɖo si da sɔ ŋutɔ. Gake le hyperparathyroidism me la, wowɔa PTH lãmetsiŋusẽa wògbɔa eme, si wɔnɛ be ƒuwo nɔa calcium dona ɖa atraɖii, si wɔnɛ be ƒuwo nɔa sue eye wogbãna. Tsɔ kpe ɖe eŋu la, calcium si sɔ gbɔ wu si ƒo ƒu ɖe ʋua me ate ŋu aƒu gbe ɖe ayiku (si ate ŋu awɔ kpe), ʋukawo, dzitodzito, kple ŋutinu bubuwo me, si ahe lãmesẽkuxi vovovowo vɛ.
Nukawoe nye nɔnɔme sia ƒomevi veviwo?
Woate ŋu ama hyperparathyroidism ɖe hatsotso vevi etɔ̃ me, eye woda wo ɖe hatsotsowo me le alesi wòdzɔnae nu.
| Ƒomevi | Kpuie ko la,... |
|---|---|
| Gbãtɔ ƒe hyperparathyroidism | Kuxia le go sia me ku ɖe parathyroid gland ŋutɔ ŋu. Dɔdzẽ (zi geɖe la, menye kansa o) le lãkusia me alo lãkusia ƒe lolome nana ŋutilãa wɔa PTH lãmetsiŋusẽ ne mehiãe o gɔ̃ hã. |
| Parathyroidism si nye hyperparathyroidism evelia | Menye lãkusiawo ƒe vodadae le afisia o. Atikewɔwɔ ƒe nɔnɔme bubu (zi geɖe la, Ayikudɔ si nɔa anyi didi) nana be calcium ƒe agbɔsɔsɔ si le ŋutilãa me dzi ɖena kpɔtɔna. Le esia ta la, parathyroid lãkusiwo dzea dɔwɔwɔ gɔme gaƒoƒo geɖe be woatsɔ axe fe si mehiã o. |
| Tertiary hyperparathyroidism ƒe dɔléle si nye hyperparathyroidism | Esia dzɔna ne womekpɔ dɔléle evelia gbɔ o ɣeyiɣi didi aɖe. Lãmetsiawo yi edzi le dɔ wɔm sesĩe akpa, wova lolona eye wowɔa PTH lãmetsiŋusẽ si dzi womate ŋu aɖu o. |
Nukawoe nye dzesiawo?
Dzesi aɖeke mele ame akpa gãtɔ siwo ŋu dɔléle sia le la ŋu o . Zi geɖe la, wokpɔa calcium ƒe agbɔsɔsɔ si sɔ gbɔ ɖe ʋu me le vo me le ʋudodokpɔ si wowɔna le susu bubu aɖe ta me. Gake ame aɖewo, vevietɔ ne woƒe calcium sɔ gbɔ ŋutɔ la, ate ŋu akpɔ dzesi siwo gbɔna:
- Ƒu kple ƒunukpeƒewo ƒe vevesese
- Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ
- Ðeɖiteameŋu kple ɖeɖiteameŋu ɣesiaɣi
- Teteɖeanyi
- Esesẽna be wò susu nanɔ nu ɖeka ŋu
- Nudzroame
- Aɖuɖɔtoe kple ʋuʋudedi
- Tɔtɔ, nuwo ŋlɔɖi be
- Tsikɔwuame si gbɔ eme kple ehiã be wòaɖe aɖuɖɔ enuenu
- Miléle
Ðo ŋku edzi be dzesi siawo bɔ ŋutɔ. Menye amesiame si ŋu wo le lae ŋu hyperparathyroidism le o. Gake ne dzesi siawo gakpɔtɔ li la, anyo wu be nàyi ɖɔkta gbɔ.
Nukae hea esia vɛ?
Mina míalé ŋku ɖe susu siwo tae ƒomevi etɔ̃ siwo ŋu míeƒo nu tsoe va yi la ŋu ɖe vovo.
Nusiwo Hea Primary Hyperparathyroidism vɛ
- Adenoma: Esia nye dɔdzẽ si menye kansa o si dzɔna le parathyroid gland me. Esiae nye nusi gbɔ parathyroidism gbãtɔ si gbɔ eme tsona wu.
- Hyperplasia: Esiae nye esime parathyroid lãkusiwo dometɔ ɖeka lolona.
- Kansa:Kansa si le parathyroid glands me nye nusi mebɔ kura o .
Nusiwo Hea Secondary Hyperparathyroidism vɛ
Nusi koŋ gbɔ esia tsonae nye Ayikudɔléle si Nɔa Anyi Didi (CKD) . Ne ayikuawo mele dɔ wɔm nyuie o la, phosphate ƒe agbɔsɔsɔ si le ŋutilãa me dzina ɖe edzi eye vitamin D ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna. Esia wɔnɛ be calcium ƒe agbɔsɔsɔ si le ʋua me dzi ɖena kpɔtɔna. Eyata be woatsɔ axe calcium ƒe anyimanɔmanɔ sia ta la, parathyroid lãkusiwo wɔa PTH lãmetsi si sɔ gbɔ akpa.
Tsɔ kpe ɖe eŋu la, vitamin D ƒe anyimanɔmanɔ vevie (le ɣe ƒe keklẽ ƒe anyimanɔmanɔ alo nunyiame ƒe veve ta) hã ate ŋu ahe esia vɛ.
Aleke woawɔ ade dzesi nɔnɔme sia?
Wò ɖɔkta aɖo to wò dzesiwo, ado wò kpɔ, eye wòaɖo wò ɖe dodokpɔ aɖewo wɔwɔ me ne wosusu be nɔnɔme sia le ŋuwò.
| Dodokpɔ | Nuka kpɔm nèle? |
|---|---|
| Ʋudodokpɔwo | Woléa ŋku ɖe calcium, PTH lãmetsi, vitamin D, phosphate, kple ayiku ƒe dɔwɔwɔ (Creatinine) ƒe agbɔsɔsɔ le ʋu me ŋu. |
| Gaƒoƒo 24 ƒe Aɖuɖɔ Dodokpɔ | Wodzidzea calcium agbɔsɔsɔme si le aɖuɖɔ si woƒo ƒu le gaƒoƒo 24 me. |
| Parathyroid ƒe Dɔwɔɖoɖo | Esia ate ŋu akpe ɖe ŋuwò nànya lãkusi si le dɔ wɔm akpa. Esia le vevie ŋutɔ hafi woawɔ dɔ nɛ. |
| Ultrasound Scan ƒe Dɔwɔnu | Wozãnɛ tsɔ léa ŋku ɖe lãkusi kple ayiku siwo le kɔ me ƒe nɔnɔme ŋu. |
| Ƒuwo ƒe Ʋuʋudedi Ŋuti Numekuku | Wowɔa dodokpɔ sia be woakpɔe ɖa be calcium bu le ƒuawo me eye wova le sue hã (Osteoporosis). |
Aleke wowɔa atike nɛ?
Atikewɔwɔ ƒe mɔnuwo nɔ te ɖe ne dɔlélea ƒe ƒomevi gbãtɔ alo evelia le ŋuwò kple alesi dɔlélea nu sẽe dzi.
Atikewɔwɔ na hyperparathyroidism gbãtɔ
Esia gbɔ kpɔnu nyuitɔ kekeake si anɔ anyi ɖaa wue nye be woawɔ dɔ (parathyroidectomy) atsɔ aɖe lãkusi alo lãkusi siwo wɔa dɔ fũu akpa la ɖa. Le amekoko sia megbe la, ame siwo wu 90% trɔna yia ʋu me calcium ƒe agbɔsɔsɔ si sɔ gbɔ.
Ne mexɔ ƒe 50 haɖe o, dzesiwo le ŋuwò, calcium sɔ gbɔ ŋutɔ, ayiku me kpewo le ŋuwò, alo ƒu tsɛwo le ŋuwò la, wò ɖɔkta aɖo aɖaŋu na wò godoo be nàwɔ dɔ na wò.
Le nɔnɔme siwo mesẽ o eye mehiã be woawɔ dɔ na wò o me la, wò ɖɔkta alé ŋku ɖe wò nɔnɔmea ŋu edziedzi. Eye ɣeaɖewoɣi la:
- Bisphosphonates: Atike siawo xea mɔ na calcium ƒe dodo le ƒuwo me eye wodoa ŋusẽ wo.
- Calcimimetics: Atike siawo "blea" parathyroid glands be woaɖe lãmetsi si nye PTH ƒe wɔwɔ dzi akpɔtɔ.
- Agbenɔnɔ ƒe tɔtrɔ: Woate ŋu aɖo aɖaŋu na wò be nàdzudzɔ atike aɖewo nono (e.g., thiazide diuretics, lithium) eye nàwɔ tɔtrɔ le nuɖuɖu ŋu.
Atikewɔwɔ na hyperparathyroidism evelia
Nu vevitɔ le afisiae nye be woada nusi gbɔ wòtso , abe ayikudɔléle dzi ɖuɖu kple vitamin D ƒe anyimanɔmanɔ dada ene.
- Ame si ŋu ayikudɔ le ate ŋu ahiã be woado ayiku alo ayiku dodo nɛ.
- Wona atikewo abe phosphate binders ene be woatsɔ aɖe phosphate ƒe agbɔsɔsɔ dzi akpɔtɔ le ʋua me.
- Wozãa vitamin D kple calcimimetic atikewo hã hena esia wɔwɔ.
Ne atikewɔwɔ siawo mete ŋu ɖu nɔnɔmea dzi o la, ate ŋu ahiã be woawɔ dɔ nɛ.
Nu vevitɔe nye be, mègano vitamin D alo calcium-tikewo le ɖokuiwò si ko o. Kpɔ wò ɖɔkta gbɔ ɣesiaɣi eye nàzã wo abe alesi wogblɔe ene ko. Ɣeaɖewoɣi la, nusiawo ate ŋu ana nuwo nagagblẽ ɖe edzi.
Gbedasi si Wotsɔ Yi Aƒeme
- Hyperparathyroidism nye nɔnɔme si me calcium ƒe agbɔsɔsɔ le ʋu me dzina ɖe edzi le lãmetsi si nye PTH si parathyroid glandwo wɔ fũu akpa ta.
- Zi geɖe la, dzesi aɖeke koŋ menɔa eŋu o. Àte ŋu akpɔ dzesi siwo bɔ abe ɖeɖiteameŋu kple ƒu ƒe vevesese ene.
- Kuxi aɖe si le lãkusia ŋutɔ me gbɔe ƒomevi gbãtɔa tsona, gake nusi koŋ gbɔ ƒomevi evelia tsonae nye ayikudɔ si nɔa anyi didi.
- Wotoa ʋu, aɖuɖɔtoe dodokpɔ, kple scan dzi dea dzesi dɔlélea.
- Atike nyuitɔ kekeake na ƒomevi gbãtɔe nye amekoko be woaɖe lãkusi si ŋu dɔlélea le la ɖa.
- Kpɔ wò ɖɔkta ɣesiaɣi hafi nàzã atike alo vitamin ɖesiaɖe.
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