Ðe wò ʋu le ɣiea? Mina míasrɔ̃ nu tso Hyperviscosity Syndrome ŋu le nya bɔbɔewo me!

Èse ʋu ƒe sisi ŋu nya kpɔa? Esia ate ŋu anye nu yeye na wò. Ʋu si le míaƒe ŋutilã me menye tsi abe tsi ene o, ke boŋ enye nusi me tsi le vie. Gake ne ʋeʋẽ sia va lolo wu alesi wòhiã ya ɖe? Ɣemaɣie míekpɔa nɔnɔme si ŋu míele nu ƒom tsoe si woyɔna be ``Hyperviscosity Syndrome''. Esiae nye esime wò ʋu va nɔa ʋeʋẽm ŋutɔ eye mete ŋu toa wò ʋukawo me nyuie o.

Nukae Nye Hyperviscosity Syndrome ƒe Dɔléle? Mina míase egɔme bɔbɔe.

Kpuie ko la, `(Hyperviscosity Syndrome)` fia be wò ʋu va ƒoa ke ɖe to ŋutɔ . Bu eŋu abe anyitsi ene. Anyi le ʋeʋẽm wu tsi, eye nenemae wòdzɔna le afisia hã. Nuwo abe ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo ene le míaƒe ʋu me. Ne esiawo dometɔ ɖeka alo esi wu nenema ƒe agbɔsɔsɔ dzi ɖe edzi alo ne ʋumenugbagbevi dzĩawo ƒe nɔnɔme mesɔ o la, ʋua ate ŋu aƒo ŋutɔ. Ele abe ɖe wotsɔ wɔ vi aɖe kpe ɖe nuɖuɖu si woɖa ŋu eye wòƒona ene.

Ne ʋu le ƒoƒom alea la, metoa ʋuka tsɛ siwo le míaƒe ŋutilã katã me bɔbɔe o. Ɣemaɣie kuxiwo dzea dodo gɔme.

Ðe nɔnɔme sia ate ŋu anye afɔkua?

Ẽ, Hyperviscosity Syndrome nye dɔléle sesẽ aɖe . Ènya nusi wònyea? Ne ʋu mele sisim nyuie o la, míaƒe ŋutinu veviwo (abe ahɔhɔ̃, dzi, kple ayiku ene) mekpɔa ɔksidzin kple nunyiame siwo wohiã o. Esia ate ŋu ana ʋukawo naxe eye ŋutinuwo nawɔ dɔ nyuie o.

Ne nɔnɔme sia dze ɖevi sue aɖe dzi la, ate ŋu akpɔ ŋusẽ ɖe woƒe tsitsi kple tsitsi dzi tẽ . Elabena le ɣeyiɣi si me woƒe ahɔhɔ̃ kple ŋutilã le tsitsim kabakaba me la, ʋu ƒe sisi ƒe gbegblẽ nye kuxi gã aɖe. Eyata ele vevie ŋutɔ be míanya esia.

Amekae ate ŋu axɔ Hyperviscosity Syndrome wu?

Togbɔ be nɔnɔme sia ate ŋu adze ame sia ame dzi hã la, ame aɖewo le afɔku me wu. Amesiwo ŋu dɔléle aɖe si mebɔ o si woyɔna be Waldenstrom macroglobulinemia le koŋue le afɔku me be woaxɔ Hyperviscosity Syndrome. Esiae nye ne protein ƒomevi tɔxɛ aɖe si woyɔna be macroglobulin le míaƒe ʋu me va sɔ gbɔ akpa. Le akɔntabubuwo nu la, amesiwo ŋu Waldenstrom macroglobulinemia le ƒe 30% kple edzivɔ axɔ Hyperviscosity Syndrome le woƒe agbemeɣeyiɣi aɖe me.

Nukae nye Hyperviscosity Syndrome ƒe dzesiwo? Mina míanɔ ŋudzɔ!

Nɔnɔme sia ƒe dzesiwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ, gake míate ŋu ama wo ɖe ƒomevi siwo bɔ kple esiwo mebɔ o me.

Dzesi siwo bɔ:

• Taɖuame: Taɖuame enuenu, ɣeaɖewoɣi la, esẽna ŋutɔ.
• Alɔ̃madɔmadɔ: Ame aɖewo ate ŋu akpɔ nɔnɔme siwo ɖi alɔ̃madɔmadɔ.
• Ŋutilã ƒe amadede biã: Ɣeaɖewoɣi la, teƒewo abe mo kple asiwo ene ate ŋu adze abi.

Dzesi siwo mebɔ o, gake wole vevie:

• Akɔtave: Akɔtave ate ŋu adzɔ, abe dzidɔ ene.
• Azɔlizɔzɔ sesẽ: Azɔlizɔzɔ ate ŋu asesẽ, abe ɖe mègada asɔ o ene.
• Tosese ƒe kuxiwo: Ðewohĩ àse le ɖokuiwò me be yeƒe to megale to ɖom o, alo àte ŋu ase gbeɖiɖi vovovowo le wò to me.
• Ʋu si dona edziedzi: Le kpɔɖeŋu me, ʋu si dona le aɖuwo me kple ʋu si dona le ŋɔti me enuenu.
• Yagbɔgbɔ sesẽ (Dyspnea): Àte ŋu ase le ɖokuiwò me be gbɔgbɔ le sesẽm na ye ne èle atrakpui liam alo le dɔ si me kɔ gɔ̃ hã wɔm.
• Vertigo: Àte ŋu ase le ɖokuiwò me be yeƒe ta le ʋuʋum, abe ɖe wò ta le tsatsam ene, eye màte ŋu anɔ tsitre o.
• Nukpɔkpɔ ƒe tɔtrɔ: Nukpɔkpɔ si me kɔ o kple nukpɔkpɔ eve ate ŋu adzɔ.

Ne dzesi siawo dometɔ ɖeka alo esi wu nenema gakpɔtɔ le ŋuwò la, anyo wu godoo be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo. Mègatsi dzodzodzoe o, gake mègaŋe aɖaba ƒu wo hã dzi o.

Nukae hea Hyperviscosity Syndrome vɛ le vidzĩ suewo me?

Susu tɔxɛ geɖe li siwo tae nɔnɔme sia ate ŋu adzɔ ɖe vidzĩ si wodzi yeyee dzi:

• Domenyiŋusẽfianu ƒe dɔlélewo: Le kpɔɖeŋu me, nɔnɔmewo abe ``Down syndrome``.
• Suklidɔ le fufɔfɔ me: Ne suklidɔ nɔ vidadaa ŋu le fufɔɣi la, ate ŋu adze vidzĩa dzi.
• Domenyiŋusẽ ƒe dɔléle: Ne dɔléle siawo nɔ ame aɖe ŋu le ƒomea me kpɔ.
• Vidzidɔ ƒe ka ƒe ƒoƒo megbe: Esia hã ate ŋu anye nusi gbɔ wòtso le go aɖewo me.
• Ʋudodo na venɔvi kple venɔvi: Esia ate ŋu adzɔ ne ʋuka siwo mesɔ o le venɔvi siwo ɖi wo nɔewo dome le vidzidɔa me le wo dome.

Nukawoe hea nɔnɔme sia vɛ le ame tsitsiwo me?

Le ame tsitsiwo gome la, abe alesi míegblɔe va yi ene la, `(Waldenstrom macroglobulinemia)` ye nye nusi koŋ gbɔ wòtsona. To vovo na ema la, ate ŋu anye nu bubu geɖe siwo gbɔ wòtsona:

• Ʋumenugbagbeviɣidɔ ƒomeviwo: Le kpɔɖeŋu me, `(Acute myeloid leukemia - AML)` kple `(Leukemia)` ƒomevi bubuwo.
• Ya si mebɔ o si nɔa anyi didi: Esia ate ŋu atso nusiwo le abe gbɔgbɔmedɔléle aɖewo ene gbɔ.
• Kadodo ƒe dɔlélewo: Le kpɔɖeŋu me, dɔlélewo abe `(Rheumatoid arthritis)` kple `(Lupus)`.
• Cryoglobulinemia: Nɔnɔme si me protein siwo mesɔ o dzɔna le ʋua me.
• Essential thrombocythemia: Ʋumenugbagbeviɣidɔ ƒe dzidziɖedzi ɖedzesi aɖe.
• Multiple myeloma: Kansa si le ƒumeŋuɖui me.
• (Paraneoplastic syndromes ƒe dɔlélewo):Dzesi siwo kansa hena vɛ le ŋutilã ƒe akpa bubuwo ƒe ƒuƒoƒo.
• (Polycythemia vera): Ʋumenugbagbevi dzĩwo ƒe dzidziɖedzi fũ akpa.
• (Sjögren ƒe dɔléle): Nɔnɔme aɖe si gblẽa nu le lãkusi siwo naa tsi nɔa ŋutilãa me ŋu.
• Myelodysplastic syndrome: Kuxi si le lãmenugbagbeviwo ƒe wɔwɔme le ƒumeŋuɖui me ŋu.

Ŋkɔ siawo ate ŋu adze na wò be woatɔtɔ vie. Nu vevitɔ si dzi wòle be míaɖo ŋkui enye be menye nɔnɔme siawo katãe hea Hyperviscosity Syndrome vɛ o, gake be nɔnɔme si le ete abe esia ene ate ŋu ana ʋu naƒo.

Aleke woawɔ anya Hyperviscosity Syndrome? (Dɔléle ƒe dzesi) .

Zi geɖe la, ɖɔktawo dea dzesi dɔléle sia to ʋudodokpɔ geɖe wɔwɔ me , eye wo dometɔ aɖewoe nye:

• Ʋuka me gas dodokpɔ: Eléa ŋku ɖe oxygen kple carbon dioxide ƒe agbɔsɔsɔ si le ʋua me ŋu.
• Bilirubin dodokpɔ: Eléa ŋku ɖe bilirubin, si nye nu ɣi aɖe si dona ne ʋumenugbagbevi dzĩwo gblẽ la ƒe agbɔsɔsɔ ŋu.
• Suklidɔ dodokpɔ le ʋu me: Kpɔ sukli (glucose) ƒe agbɔsɔsɔ le ʋu me ɖa.
• Ʋu ƒe xexlẽme blibo (CBC): Edzidzea ʋua ƒe akpa vovovoawo katã ƒe agbɔsɔsɔ, siwo dometɔ aɖewoe nye ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple proteinwo.
• Creatinine dodokpɔ: Eléa ŋku ɖe alesi ayikuawo le dɔ wɔm nyuie ŋu.
• Aklã ƒe dɔwɔwɔ dodokpɔ: Eléa ŋku ɖe aklã me proteinwo ŋu.
• Serum viscosity alo ʋu bliboa ƒe ʋeʋẽ dodokpɔ: Dodokpɔ siwo dzidzea ʋua ƒe ʋeʋẽ pɛpɛpɛ.
• Protein dodokpɔ: Dzidze protein vovovo siwo le ʋua me ƒe agbɔsɔsɔ.

Wonɔ te ɖe dodokpɔ siawo me tsonu dzi be ɖɔktaa ate ŋu anya nenye be Hyperviscosity Syndrome le ŋuwò alo mele ŋuwò o.

Nukawoe nye atike siwo wozãna na esia? (Atikewɔwɔ ƒe mɔnuwo) .

Atikewɔwɔ na ``Hyperviscosity Syndrome'' ateŋu ato vovo le nusi gbɔ wòtso nu . Esi wònye be tsikuɖiɖi ate ŋu agblẽ ɖe edzi le nɔnɔme sia me ta la, ɖɔkta ate ŋu aɖo aɖaŋu be woade tsi le ʋuka me (IV) .

Le dɔléle sesẽ aɖewo me la, ɖɔktawo ate ŋu azã atikewɔmɔnuwo abe:

• Dodo na ame ƒe akpa aɖe: Esia bia be woaɖe ʋu sue aɖe ɖa eye woatsɔ dzetsi aɖo eteƒe. Esia ate ŋu akpe ɖe ʋua ƒe ʋeʋẽ ŋu dzi akpɔtɔ.
• Plasmapheresis: Esia bia be woaɖe ʋumenugbagbeviɣi sue aɖe, si nye ʋua ƒe akpa si nye tsi la ɖa, eye woatsɔ ʋumenugbagbeviɣitike aɖo eteƒe. Esia kpena ɖe ame ŋu wòɖea protein siwo gblẽa nu le ame ŋu ɖa le ʋua me eye wòɖea eƒe ʋeʋẽ dzi kpɔtɔna.

Wò ɖɔktae ɖoa atikewɔwɔ siawo, le wò nɔnɔme kple nusi gbɔ wòtso nu.

Ðe mɔ aɖewo li siwo dzi woato axe mɔ ɖe Hyperviscosity Syndrome nua?

Le nyateƒe me la, mɔ aɖeke meli si dzi woato axe mɔ ɖe `(Hyperviscosity Syndrome)` nu keŋkeŋ o. Gake ne èfɔ fu la, nu aɖewo li nàte ŋu awɔ atsɔ aɖe afɔku si le viwòa ƒe dɔléle sia xɔxɔ me dzi akpɔtɔ :

• Na woado domenyiŋusẽfianu kpɔ: Esia akpe ɖe ŋuwò nàse mɔnukpɔkpɔ siwo li be nàdzi vi si ŋu domenyiŋusẽfianu ƒe dɔléle aɖe le la gɔme.
• Ðu nuɖuɖu si me nunyiame le eye nàde kame edziedzi : Esia ate ŋu aɖe fufɔfɔ ƒe suklidɔ xɔxɔ ƒe afɔkua dzi akpɔtɔ.
• Yi atikewɔƒewo eye nàdoe kpɔ abe alesi nèɖoe ene: Ele vevie ŋutɔ be nàwɔ ɖe atikewɔlawo ƒe aɖaŋuɖoɖowo dzi le wò fufɔɣi katã.

Nukae dzɔna ɖe amesi ŋu Hyperviscosity Syndrome le dzi? (Do afɔ)

Hyperviscosity Syndrome nye dɔléle si hiã be woawɔ atike nɛ enumake . Ne womewɔ atike nɛ o la, ate ŋu ahe kuxi siwo ate ŋu ade ame ƒe agbe afɔku me kple ŋutinuwo ƒe dɔmawɔmawɔ nyuie vɛ.

Nya nyuiae nye be zi geɖe la , vidzĩwo kple ame tsitsi siwo wowɔ atike na ɖe game dzi la hayana keŋkeŋ tso nɔnɔme sia me . Gake ne dɔléle aɖe si nɔa anyi didi si gbɔ wòtso gbɔe hyperviscosity syndrome la tso la, ahiã be nàyi atikewɔwɔ dzi be wòagadzɔ ake o.

Aleke Hyperviscosity Syndrome sena le eɖokui me?

Esia ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ. Ne ʋu le ƒoƒom la, ʋu ƒe sisi yi ahɔhɔ̃a me dzi ɖena kpɔtɔna, si ate ŋu ana ta naɖu ame, taɖuame, alo alɔ̃dɔdɔ gɔ̃ hã . Ame aɖewo hã ate ŋu asesẽ na gbɔgbɔ alo woƒe ŋkuwo megakpɔa nu nyuie o .

Nu bubu kawoe kpɔa ŋusẽ ɖe ʋu ƒe sisi dzi?

Susu geɖewo li siwo tae wò ʋu ate ŋu aƒo ƒu ɖo. Wò ʋu ate ŋu aƒo ne wò ʋumenugbagbevi dzĩwo ƒe nɔnɔme mesɔ o . Ate ŋu azu ʋeʋẽ hã ne wò ʋumenu aɖewo abe ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, alo protein siwo le wò ʋu me ene ƒe agbɔsɔsɔ sɔ gbɔ ɖe wò ʋu me le mɔ si mesɔ o nu .

Mlɔeba la, nusiwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Enyo, eyata fifia èse nusi ŋu míeƒo nu tsoe gɔme nyuie wu, ``Hyperviscosity Syndrome.`` Ðo ŋku edzi be, ɣeyiɣi sia mee ʋua ƒoa ke eye mete ŋu sina nyuie le ŋutilã bliboa me o.

Esia ate ŋu adzɔ le amesiwo ŋu ʋudɔléle aɖewo le, kpakple vidzĩ siwo wodzi yeyee siwo ŋu domenyiŋusẽfianu alo domenyiŋusẽfianu ƒe dɔléle aɖewo le hã dzi.

Togbɔ be esia nye dɔléle sesẽ aɖe hã la, ne wokpɔe dze sii hedae kaba la, ame akpa gãtɔ hayana keŋkeŋ. Eyata ne dzimaɖitsitsi alo dzesi aɖe le mia alo viwòa ŋu la, yi ɖɔkta gbɔ enumake hena aɖaŋuɖoɖo. Mègatsi dzodzodzoe o, nu vevitɔ kekeakee nye be woana nyanya wò.

Ne nya bubu aɖewo gale asiwò la, mègahe ɖe megbe le wò ɖɔkta biabia me o:

• Nukae nye nusi ate ŋu ahe `(Hyperviscosity Syndrome)` sia vɛ wu?
• Dodokpɔ kawoe wowɔna tsɔ dea dzesi esia?
• Aleke wowɔa atike nɛ?
• Ðe wòahiã be mayi atikewɔwɔa dzia?
• Ne vi bubu le asinye la, ɖe wòanya wɔ be nɔnɔme sia nadze eya hã dzia?

Bia nya siawo tɔgbe eye nàkpɔ kuxi siwo katã le susu me na wò la gbɔ.

` Hyperviscosity syndrome, ʋu ƒe sisi, ʋu ƒe dɔléle, dzesiwo, atikewɔwɔ, ɖeviwo ƒe lãmesẽ, ame tsitsiwo ƒe lãmesẽ