Mina míasrɔ̃ nu tso phosphate binder siwo ayikudɔlélawo nona ŋu ko.

Ðe wò ɖɔkta gblɔ na wò be nàno atike aɖe si woyɔna be ‘Phosphate Binders’a? Alo ède dzesii be phosphate si le wò ʋu me sɔ gbɔa? Ŋkɔ sia ate ŋu aɖi nusi wɔ nuku vie na wò. Gake mègatsi dzi o. Esia nye atike si woŋlɔna na amesiwo ŋu ayikudɔ le zi geɖe. Egbea, míaƒo nu tso eŋu le mɔ bɔbɔe aɖe ŋutɔ si gɔme nàte ŋu ase nu.

Kpuie ko la, nukae nye phosphate-blanu siawo?

Ele bɔbɔe ŋutɔ. Phosphate binders nye atike ƒomevi aɖe si wonana be wòaɖe phosphate ƒe agbɔsɔsɔ dzi akpɔtɔ le wò ŋutilã me. Phosphate nye mineral si míaƒe ŋutilã hiã. Gake abe nusianu ene la, eƒe agbɔsɔsɔ fũ ate ŋu ahe kuxiwo vɛ. Ɣemaɣie ɖɔkta aɖe aŋlɔ atike sia na wò.

Togbɔ be woate ŋu aƒle atike siawo dometɔ aɖewo le atikedzraƒe hã la, mele be nàzã wo gbeɖe ne mèƒo nu kple wò ɖɔkta o. Esia le vevie ŋutɔ.

Nukatae míaƒe ŋutilã hiã phosphate?

Phosphate nye elektrikŋusẽ si le míaƒe ŋutilã me. Kpuie ko la, enye tomenu si hiã vevie be míaƒe ŋutilã nate ŋu awɔ dɔ. Bu eŋu kpɔ, phosphate kpena ɖe mía ŋu be míaƒe ƒuwo kple aɖuwo sẽna. Menye ema ɖeɖeko o, ke phosphate hã le vevie na míaƒe ŋutilã ƒe lãmenugbagbeviwo ƒe ŋusẽ wɔwɔ, lãmenugbagbeviwo ƒe lãkusiwo wɔwɔ, kple DNA (Deoxyribonucleic acid), si me míaƒe domenyiŋusẽfianu ŋuti nyatakakawo le la wɔwɔ.

Míekpɔa phosphate sia tso nuɖuɖu siwo míeɖuna kple esiwo míenona me. Ame si le lãmesẽ me ƒe ŋutilã xɔa agbɔsɔsɔ si wòhiã la ko, eye susɔea dona le aɖuɖɔ kple aɖuɖɔ me. Gake le susu aɖewo ta, vevietɔ ne ayikuawo mele dɔ wɔm nyuie o la, ŋutilãa mete ŋu ɖea phosphate si sɔ gbɔ wu la doa goe le mɔ sia nu o. Ɣemaɣie phosphate ƒoa ƒu ɖe ʋua me eye wòhea kuxiwo vɛ.

Amekae hiã phosphate-blanu sia?

Zi geɖe la, ɖɔkta aŋlɔ atike sia na wò ne phosphate si le wò ʋu me sɔ gbɔ sã wu alesi wòle dzɔdzɔmee. Woyɔa nɔnɔme sia le atikewɔwɔ me be hyperphosphatemia .

Nɔnɔme sia ate ŋu adzɔ wu le amesiwo ŋu ayikudɔléle si nɔa anyi didi (CKD) le kple amesiwo ƒe ayiku me gblẽ keŋkeŋ eye wole ʋumenugbagbeviɣidɔ wɔm.

Nukatae wonaa atike sia dɔnɔ siwo woɖea ʋu le?

Esɔ be phosphate naƒo ƒu ɖe ʋua me ne ayikuawo le dɔ wɔm. Ne phosphate ƒe agbɔsɔsɔ dzi ɖe edzi la, edzea calcium hehe tso ƒuwo me gɔme. Le ɣeyiɣi aɖe megbe la, esia nana ƒuawo gbɔdzɔna eye wònaa ƒuwo ƒe gbagbã ƒe afɔkua dzina ɖe edzi. Wotsɔa phosphate binders naa dɔnɔ siwo woɖea tsi le lãme na ame be woatsɔ axe mɔ ɖe dɔléle siwo do ƒome kple ƒuwo nu.

Nukae nye phosphate ƒe agbɔsɔsɔ si sɔ nyuie le ʋua me?

Fosfate ƒe agbɔsɔsɔ si sɔ le ʋu me na ame tsitsi si le lãmesẽ me le miligram 2.8 va ɖo 4.5 le desilita ɖeka me (mg/dL) . Le ɖevi suewo gome la, xexlẽme sia lolo vie, le 4.0 va ɖo 7.0 mg/dL dome.

Nuɖuɖu kple nunono kawoe me phosphate sɔ gbɔ ɖo wu?

Ne ayikudɔ le ŋuwò la, ele be nàɖɔ ŋu ɖo vevietɔ le nusiwo nèɖuna kple nusiwo nènona ŋu, elabena abe alesi wòle le atikewo nono gome ene la, nuɖuɖu dzi ɖuɖu hã le vevie ŋutɔ.

Aleke atike sia si woyɔna be phosphate binder wɔa dɔe?

Alesi esia wɔa dɔe la wɔ nuku ŋutɔ. Ne míeɖu nu la, phosphate si le nuɖuɖu ma me la toa dɔgbo suea ƒe titina, si míeyɔna be jejunum , la me gena ɖe míaƒe ŋutilã me.

Ne èno phosphate binder sia kpe ɖe nuɖuɖu ŋu la, atike la gena ɖe wò dɔgbo me eye "blaa" kple phosphate si sɔ gbɔ ɖe wò nuɖuɖu me. Ele abe magnet ene. Ne elé ɖe eŋu la, mate ŋu age ɖe wò ʋukawo me o. Emegbe, phosphate si sɔ gbɔ wu la dona le wò ŋutilã me le wò aɖuɖɔ me. Ele bɔbɔe ŋutɔ, alo?

Phosphate binder ƒomeviwo kple alesi woawɔ akpɔ woe?

Fosfate-blanu ƒomevi vovovowo li. Le wò nɔnɔmea nu la, wò ɖɔkta atia ƒomevi si sɔ na wò wu.

• Calcium carbonate - (le kpɔɖeŋu me, Tums®, Alka-Seltzer®) .
• Sevelamer - (le kpɔɖeŋu me, Renvela®, Renagel®) .
• Lanthanum carbonate - (le kpɔɖeŋu me, Fosrenol®) .
• Kalsium acetate - (le kpɔɖeŋu me, PhosLo®, Phoslyra®) .
• Sukroferric oxyhydroxide - (e.g. Velphoro®) ƒe ʋuʋudedi.

Ka ƒomevie nye nyuitɔ kekeake?

Zi geɖe la, woŋlɔa atike siwo me calcium le (abe calcium carbonate ene) na amewo. Gake numekuku aɖewo ɖee fia be ne wozã atike siawo siwo me calcium le ɣeyiɣi didi la, calcium si sɔ gbɔ wu ate ŋu aƒo ƒu ɖe ʋukawo me. Woyɔa esia be ʋukawo me calcification . Esia ate ŋu ana ʋu ƒe sisi alo ʋusɔgbɔdɔ ƒe afɔkua nadzi ɖe edzi. Le susu sia ta la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò ɣeaɖewoɣi be nàzã atike si me calcium mele o (abe Sevelamer ene).

Aleke wòle be mano atike sia?

Esiae nye nu vevitɔ kekeake. Be atike sia nawɔ dɔ nyuie la, ɣeyiɣi si nànoe le vevie ŋutɔ. Wɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi pɛpɛpɛ.

• Gblɔ atike bubu ɖesiaɖe si zãm nèle (vitamin kple gbetikewo hã le eme) na wò ɖɔkta, elabena atike aɖewo ate ŋu awɔ dɔ kple esiawo.
• Le atike ƒomevi si woazã nu la, mɔ si dzi wòle be woanoe ate ŋu ato vovo:
• Ele be woaɖu wo dometɔ aɖewo ahami wo miniti 10-15 hafi aɖu wo .
• Ele be nàɖu wo dometɔ aɖewo ahami ne ènya dze nuɖuɖu gɔme ko .
• Ele be woami wo dometɔ aɖewo bliboe , kple nuɖuɖua ƒe nu eve alo etɔ̃ gbãtɔwo .
• Wo dometɔ aɖewo va le atikekui ƒe nɔnɔme me. Ele be woatsɔ wo alɔ tsi me eye woano wo kple nuɖuɖu ƒe nu eve alo etɔ̃ gbãtɔwo .
• Ele be woaɖu wo dometɔ aɖewo ahami wo enumake ne woɖu wo vɔ .

Ðe atike sia ƒe nugbegblẽ le ame ŋu aɖewoa?

Abe atike ɖesiaɖe ene la, atike sia ƒomevi ate ŋu ahe nugbegblẽ suesuesuewo vɛ, gake menye amesiamee xɔa wo o.

Ne dzesi siawo ɖea fu na wò la, ƒo nu kple wò ɖɔkta. Ðewohĩ woate ŋu atrɔ wò atikewo.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Ne èkpɔ nugbegblẽ sesẽwo la, kpɔ egbɔ be yegblɔe na wò ɖɔkta. Azɔ hã, ɣeaɖewoɣi la, phosphate ƒe dzidziɖedzi le ʋua me ate ŋu ana calcium ƒe agbɔsɔsɔ dzi naɖe akpɔtɔ le ŋutilãa me. Woyɔa esia be hypocalcemia . Ne èkpɔ dzesi siwo gbɔna la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake.

• Lãmetsiwo ƒe ʋuʋu
• Ŋkuɖodzinyawo ƒe kuxiwo
• Dzikudodo susu aɖeke manɔmee
• Nuyiwo, aɖe, asibidɛwo, alo afɔwo ƒe ʋuʋu
• Alɔ̃madɔmadɔ
• Dzi ƒe tsotso ƒe dɔmawɔmawɔ nyuie (Arrhythmia) .

Nya siwo wòle be nàbia wò ɖɔkta

Ne èyi wò ɖɔkta gbɔ la, biabia siawo nenɔ susu me na wò. Wo biabia ate ŋu akpe ɖe ŋuwò nàse wò nɔnɔmea gɔme nyuie wu.

• "Fosfate binder ka ƒomevie nèkafu nam?"
• "Nukae nye nugbegblẽ le ame ŋu siwo ate ŋu ado tso eme?"
• "Aleke wòle be mano atike sia? Do ŋgɔ na nuɖuɖu alo le nuɖuɖu vɔ megbe?"
• "Zi nenie wòle be manoe gbesiagbe?"
• "Atikekui nenie wòle be mano na nuɖuɖu vevitɔ? Atikekui nenie wòle be mano na numeɖenu?"
• "Ðe atike bubu aɖewo li siwo wòle be madzudzɔ nono esime mele atike sia nom?"
• "Ɣeyiɣi didi kae wòahiã be mano atike sia?"
• "Dodokpɔ ka ƒomevie wole wɔwɔm be woakpɔe ɖa be atike sia wɔa dɔ hã?"
• "Ðe wòhiã be makpɔ nuɖuɖuŋutinunyala aɖea?"