Ðe nèle nuƒoƒo ƒe ŋutete bum vivivia? Esia ate ŋu anye Primary Progressive Aphasia (PPA) .

Ðe nèsena le ɖokuiwò me ɣeaɖewoɣi be yemate ŋu akpɔ nya siwo sɔ agblɔ oa? Alo ɖe wòsesẽna na wò be nàse nya si gblɔm ame aɖe le la gɔmea? Ðewohĩ ènya ame aɖe le wò ƒomea me, vidada alo vifofo, si ŋu kuxi sia ƒomevi le? Togbɔ be nu siawo adze abe nu dzɔdzɔe siwo dzɔna ne èle tsitsim ene hã la, ɣeaɖewoɣi la, woate ŋu anye nane si de to wu ƒe dzesi. Egbea míele nu ƒom tso nɔnɔme mawo dometɔ ɖeka ŋu, si nye Primary Progressive Aphasia (PPA).

Nuka tututue nye PPA?

Kpuie ko la, Primary Progressive Aphasia (PPA) nye ahɔhɔ̃medɔléle. Enye ahɔhɔ̃mekawo ƒe dɔmawɔmawɔ nyuie si nana lãmekawo ƒe dɔwɔwɔ gbɔdzɔna vivivi eye wògblẽna ɖe edzi vivivi le ɣeyiɣi aɖe megbe. Etɔxɛe la, egblẽa nu le ahɔhɔ̃a ƒe akpa siwo kpɔa gome le míaƒe nuƒoƒo, nuxexlẽ, nuŋɔŋlɔ, kple gbegɔmese ŋutete me.

Tsɔe be míaƒe ahɔhɔ̃ le abe agbalẽdzraɖoƒe gã aɖe ene. Wodzra agbalẽwo, nyawo, kple gɔmesese siwo katã ku ɖe gbegbɔgblɔ ŋu ɖo ɖe agbalẽdzraɖoƒe ma ƒe akpa tɔxɛ aɖe. PPA nye nusi tututu dzɔna ne agbalẽ siwo le akpa sia me vivivi, ɖekaɖeka, gblẽ eye womate ŋu azã wo o.

Wobua PPA be enye Frontotemporal Dementia (FTD) alo Alzheimer ƒe Tagbɔdɔléle ƒomevi aɖe . Dɔléle siawo nana míaƒe ahɔhɔ̃ ƒe ŋgɔgbe kple megbeƒuwo megawɔa dɔ o vivivi. Akpa siawo koŋue kpɔa ŋusẽ ɖe míaƒe gbegbɔgblɔ ƒe ŋutetewo dzi.

Nukawoe nye PPA ƒomevi veviwo?

PPA koŋue woma ɖe hatsotso etɔ̃ me. Nɔnɔme siwo le ƒomevi ɖesiaɖe ŋu to vovo vie. Mina míase egɔme nyuie tso kplɔ̃ sia dzi.

Nukawoe ate ŋu anye dɔléle sia ƒe dzesiwo?

Dzesiawo toa vovo le ƒomevi si ŋu míeƒo nu tsoe va yi nu. Zi geɖe la, dzesi siawo ate ŋu adze dzedze gɔme tso ƒe 50 va ɖo ƒe 70. Vivivi la, wova nɔa sesẽm ɖe edzi le ɣeyiɣi aɖe megbe.

Lopenic variant PPA ƒe nɔnɔmewo

• Esesẽ be woakpɔ nya si sɔ agblɔ.
• Nyagbe didi alo nyagbe sesẽwo gɔmesese sesẽ.
• Esesẽna be woagblɔ nyagbe didiwo wu kpuiwo.
• Tɔtɔ enuenu ne èle nu ƒom.
• Nyawo yɔyɔ vodadatɔe.
• Nya bubuwo zazã ɖe nya aɖewo teƒe (e.g. gbɔgblɔ be "avũ" ɖe "avũ" teƒe).

PPA ƒe nɔnɔme siwo me mekɔ o (agrammatic) ƒe tɔtrɔ

• Nuyiwo kple aɖe zazã sesẽ be woaɖe gbeɖiɖiwo nyuie (apraxia).
• Nu mimi sesẽ.
• Kuxi siwo le azɔlizɔzɔ kple ʋuʋu me (ʋuʋu blewu kple sesẽ, dadasɔ ƒe anyimanɔmanɔ, anyidzedze enuenu).
• Nyawo ɖeɖeɖa le nyagbewo me kple nuƒoƒo bɔbɔe (e.g., "Dada le fiẽnuɖu ge" tsɔ wu be "Maɖu fiẽnu kple Dada").
• Nyagbe didi alo nyagbe sesẽwo gɔmesese sesẽ.
• Ðewohĩ asesẽ na ame aɖewo kura be woaƒo nu eye woate ŋu ava zu mumu gɔ̃ hã .

Gɔmesese ƒe vovototo PPA ƒe nɔnɔmewo

• Nusiwo ame nyanyɛwo nye kple nusi woawɔ kpli wo ŋɔŋlɔ be.
• Gɔmesese si le nyawo ŋu dzi maɖomaɖo.
• Esesẽ be woakpɔ nya si sɔ agblɔ.
• Nuxexlẽ kple nuŋɔŋlɔ ƒe kuxiwo.

Nukae hea PPA vɛ? Ðe afɔku aɖewo lia?

Nɔnɔme sia dzɔna elabena lãmenugbagbevi siwo le míaƒe ahɔhɔ̃ ƒe akpa siwo kpɔa gbegbɔgblɔ dzi la kuna vivivi. Esia nana ahɔhɔ̃mekawo dzi ɖena kpɔtɔna. Le atikewɔwɔ me la, míeyɔa esia be atrophy .Wogblɔna be dzi ɖeɖe kpɔtɔ sia tae gbegbɔgblɔ ŋuti ŋutetewo buna ɖo.

Togbɔ be nɔnɔme sia ate ŋu adze ame sia ame dzi hã la, ame aɖewo le afɔku me wu.

• Ne ame aɖe si le ƒomea me xɔ PPA kpɔ.
• Domenyiŋusẽfianu ƒe vovototo aɖewo ƒe amesinɔnɔ , abe `(C9orf72, MAPT alo GRN)` ene.
• Ne nusɔsrɔ̃ ƒe kuxi aɖe nɔ ŋuwò le wò ɖevime.
• Alzheimer-dɔléle si le ame ŋu.

Gake ɣeaɖewoɣi la, nɔnɔme sia ate ŋu adzɔ susu aɖeke si dze ƒã manɔmee.

Aleke ɖɔkta awɔ ake ɖe esia ŋu?

Ne gbegbɔgblɔ me kuxiwo le ŋuwò la, ele be nàyi ɖɔkta gbɔ godoo. Ðɔktaa abia nya wò tso wò dzesiwo kple wò ƒomea ƒe atikewɔwɔ ŋutinya ŋu. Emegbe, woate ŋu awɔ dodokpɔ aɖewo atsɔ aɖo kpe dɔlélea dzi.

• Ahɔhɔ̃mekadodokpɔ: Woléa ŋku ɖe wò dadasɔ, wò susu ƒe dɔwɔwɔ, kple wò lãmekawo ƒe dɔwɔwɔ ŋu.
• Sidzedze dodokpɔwo: Dodokpɔ siwo dzidzea ŋkuɖoɖonudzi, tamebubu ŋutete, kple gbegbɔgblɔ ƒe ŋutetewo.
• Ahɔhɔ̃ me fotoɖeɖe: Woate ŋu awɔ MRI (Magnetic Resonance Imaging) alo CT (Computed Tomography) scan atsɔ akpɔe ɖa be ahɔhɔ̃a ƒe ʋuʋu alo tɔtrɔ bubu aɖewo le eŋu hã.

PPA dɔlélea ƒe afɔɖeɖewo

Esi dɔléle sia nu sẽna ɖe edzi vivivi le ɣeyiɣi aɖe megbe ta la, wode dzesi akpa vovovowo.

1. Akpa 1 (si fa ŋutɔ): Gbegbɔgblɔ ƒe kuxi suesuesuewo ŋutɔ dzena. Woate ŋu abui be tsitsi alo nuteɖeamedzi gbɔe wòtso. Ƒã hafi woakpɔ dɔlélea le ɣeyiɣi sia me.

2. Akpa 2 lia (si mesẽ o): Gbegbɔgblɔ ƒe kuxiwo doa mo ɖa enuenu. Wò ƒomea me tɔwo hã tea dzesidede vovototo sia. Esia dzea ŋusẽkpɔkpɔ ɖe gbesiagbedɔwo dzi gɔme.

3. Akpa 3 lia (Ele titina): Gbesiagbedɔwo va sesẽna ŋutɔ be nàwɔ le ɖokuiwò si. Nuƒoƒo na ame bubuwo kple hadede kple amewo ate ŋu ate ɖe ame dzi ŋutɔ.

4. Akpa 4 lia (Esesẽ): Esesẽna ŋutɔ be woaƒo nu ahase gbe. Kpekpeɖeŋu le gbesiagbedɔwo wɔwɔ me hiã. Ame ɖeka ƒe agbenɔnɔ ate ŋu anye afɔku.

5. Afɔɖeɖe 5 lia (si nu sẽ ŋutɔ): Nuƒoƒo kple gbegbɔgblɔ gɔmesese ƒe akpa gãtɔ bu. Nuwɔna kple tamebubu ƒe tɔtrɔwo dzɔna. Wohiã beléle gaƒoƒo 24 sɔŋ.

6. Afɔɖeɖe 6 (mlɔetɔ): Mete ŋu doa gbe alo sea gbea gɔme o. Ate ŋu agblɔ gbeɖiɖi siwo menye nyagbɔgblɔ o. Ðewohĩ ŋutete maganɔ eŋu be wòaʋuʋu o.

Ðe atike aɖe li na esia?

Nublanuitɔe la, womekpɔ atike aɖeke si ate ŋu ada PPA keŋkeŋ haɖe o.Eye manya wɔ be woaxe mɔ na dɔlélea be wòagagblẽ ɖe edzi o. Gake atikewɔmɔnu aɖewo li siwo ate ŋu akpe ɖe ame ŋu wòaɖu dzesiawo dzi, ana dɔlélea ƒe ŋgɔyiyi nagbɔdzɔ, eye wòana agbea nanɔ bɔbɔe.

Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàzã atikewɔmɔnuwo abe:

• Nuƒoƒo ƒe atikewɔwɔ: Esia kpena ɖe ame ŋu be gbegbɔgblɔ ƒe ŋutete nanɔ anyi ɣeyiɣi didi si wòanya wɔ eye wòsrɔ̃a kadodomɔnu yeyewo.
• Dzeɖoɖomɔnu yeyewo sɔsrɔ̃: Nuwo abe tokunɔgbe alo nɔnɔmetata gbalẽviwo zazã zu numame na wo.
• Atikewo: Woate ŋu aŋlɔ atikewo abe Selective Serotonin Reuptake Inhibitors (SSRI) ene be woatsɔ aɖu nuwɔna ƒe tɔtrɔ, blanuiléle, alo dzimaɖitsitsi dzi.
• Alzheimer ƒe atikewo: Ne Alzheimer ƒe dɔlélee nye nusi gbɔ PPA tso la, woate ŋu aŋlɔ atikewo abe donepezil alo rivastigmine si wozãna na nɔnɔme ma ene na ame.

Aleke agbea anɔ kple dɔléle sia?

PPA nye nɔnɔme si nu sẽna ɖe edzi le ɣeyiɣi aɖe megbe. Mlɔeba la, gbegbɔgblɔ kple dzeɖoɖo ƒe ŋutete ate ŋu abu keŋkeŋ. Ne dɔlélea le kakam ɖe ahɔhɔ̃a ƒe akpa bubuwo la, ekpɔa ŋusẽ ɖe tamebubu kple nuwɔna hã dzi.

Zi geɖe la, ƒe atɔ̃ va ɖo adre ƒe agbenɔƒe le mama dedie nu le dzesiawo ƒe gɔmedzedze megbe, gake esia toa vovo ŋutɔ tso ame ɖeka gbɔ yi bubu gbɔ. Eyata mègavɔ̃ na akɔntabubuwo o. Wò ɖɔkta koe ate ŋu ana nyatakaka nyuitɔ kekeake wò tso wò nɔnɔmea ŋu.