Mina míasrɔ̃ nu sia nu tso thyroid hormone si kpɔa wò ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi ŋu!

Ðe nèsena le ɖokuiwò me ɣeaɖewoɣi be ɖeko wò ŋutilã mele dɔ wɔm nyuie o, alo ɖeɖi te ye ŋu veviea? Alo ɖe nèsena le ɖokuiwò me ɣeaɖewoɣi abe ɖe wò ŋutilã le du dzi le ŋgɔ na wò susu ene, eye nètsia dzimaɖi veviea? Susu ɖeka si ta nusiawo tso ate ŋu anye nu sue aɖe ŋutɔ, gake le vevie ŋutɔ le wò ŋutilã me. Emae nye lãmetsi si woyɔna be thyroid hormone. Egbea, mina míaƒo nu tso nusi thyroid hormone sia nye, nusi wòwɔna ɖe míaƒe ŋutilã ŋu, kple kuxi siwo dona tso eƒe tɔtrɔ me ŋu.

Nukae Nye Thyroid Lãmetsiŋusẽ? Kpuie ko la,...

Bu wò ŋutilã abe mɔ̃ gã aɖe ene. Lãmetsiŋusẽ si woyɔna be thyroid hormone nye tɔtrɔ vevi aɖe si kpɔa mɔ̃ sia ƒe dɔwɔwɔ kabakaba dzi, si nye lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe agbɔsɔsɔme . Lãmetsiŋusẽ sia le vevie na vidzĩ sue ƒe ahɔhɔ̃ ƒe tsitsi.

Ènya amesi wɔa lãmetsi sia? Enye lãkusi sue aɖe si le abe kpakpaluʋui ene le ŋutigbalẽa te le wò kɔ ƒe ŋgɔgbe. Míeyɔnae be lãkusi si woyɔna be thyroid gland . Enye míaƒe ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe akpa aɖe .

Lãmetsiŋusẽwo le abe dɔla siwo le du dzi to míaƒe ŋutilã me ene. Wozɔa mɔ to ʋua me hegblɔa nusi woawɔ kple ɣeyiɣi si woawɔe na ŋutinu vovovowo, lãmekawo, kple lãmeka bubuwo.

Fifia míele nu ƒom tso lãmenugbagbeviwo ƒe dɔwɔwɔ ŋu . Kpuie ko la, enye nuwɔna sesẽ si trɔa nuɖuɖu si míeɖuna wòzua ŋusẽ. Lãmenugbagbevi ɖesiaɖe si le míaƒe ŋutilã me hiã ŋusẽ hafi wòate ŋu awɔ dɔ.

Le nyateƒe me la, ne míegblɔ be "thyroid hormone" la, míele nu ƒom tso lãmetsi vevi eve ŋu. Woawoe nye thyroxine (Thyroxine - T4) kple triiodothyronine (Triiodothyronine - T3) . Zi geɖe la, míeyɔa eve siawo ɖekae be "thyroid hormone". Ènya nusi? Zi geɖe la, lãmetsi si nye T4 mewɔa dɔ boo o, si fia be mekpɔa ŋusẽ boo aɖeke ɖe lãmenugbagbeviwo dzi o. Gake lãmetsi si nye T3 ye wɔa dɔ wu. Ne T4 do le lãkusi me la, míaƒe ŋutilã ƒe ŋutinu aɖewo trɔnɛ wòzua T3. Ema ko hafi wòate ŋu akpɔ ŋusẽ ɖe lãmenugbagbeviwo kple míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi.

Nu bubue nye be lãkusia hã ɖea lãmetsi aɖe si woyɔna be calcitonin . Ekpɔa calcium ƒe agbɔsɔsɔ si le ʋua me dzi eye wòɖea edzi kpɔtɔna. Ke hã, calcitonin mele ŋkɔ "thyroid hormone" me o, eye mekpɔa ŋusẽ ɖe míaƒe ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi abe T3 kple T4 ene o.

Aleke wokpɔa thyroid lãmetsi siawo ƒe agbɔsɔsɔ dzii? Enye mɔ̃ wɔnuku aɖe ŋutɔ!

Wokpɔa T4 kple T3 lãmetsi siawo ƒe wɔwɔ kple woƒe dodo dzi le mɔ si sesẽ ŋutɔ nu, gake wònya kpɔ ŋutɔ. Míeyɔa esia be nyaŋuɖoɖo ƒe mɔnu . Esia lɔ:

• Hypothalamus : Esia le wò ahɔhɔ̃ me. Ekpɔa nuwo abe ʋu ƒe sisi, dzi ƒe tsotso, ŋutilã ƒe dzoxɔxɔ, kple nuɖuɖumeŋusẽ dzi.
• Pituitary gland : Esia hã nye lãkusi sue aɖe si le ahɔhɔ̃a te, le hypothalamus te. Eƒe lolome anɔ abe pea ene. Ewɔa lãmetsiŋusẽ ƒomevi siwo ade enyi eye wòɖea wo ɖe go.
• Thyroid gland : Kpakpaluʋui si ŋu míeƒo nu tsoe va yi.
• Lãmetsiŋusẽ ʋɛ aɖewo bubuwo.

Tsɔe be esia le abe dɔwɔwɔ le dɔwɔƒe gã aɖe me ene.

1. Gbã la, hypothalamus (abe dɔdzikpɔla gã aɖe ene) si le ahɔhɔ̃a me ɖea lãmetsi aɖe si woyɔna be Thyroid-Releasing Hormone (TRH) si ɖea lãmetsi si doa ŋusẽ lãkusi .

2. TRH sia yia lãkusi si me ʋu sina tona me (abe dɔdzikpɔla ƒe kpeɖeŋutɔ ene) eye wògblɔna nɛ be wòawɔ lãmetsi si doa ŋusẽ lãkusi (TSH) eye wòaɖee ɖa .

3. Emegbe TSH sia yia lãkusi me (abe dɔwɔla ene) eye wògblɔna nɛ be wòawɔ T4 kple T3. Lãmetsiŋusẽ siwo wowɔ to mɔ sia dzi ƒe 80% lɔƒo nye T4, eye 20% mamlɛawo nye T3. Be lãkusia nawɔ T4 kple T3 siawo la, ehiã nunyiame aɖe hã si woyɔna be iodine . Míekpɔnɛ tso nuɖuɖu siwo míeɖuna me.

Fifia nusi woyɔna be ``feedback loop'' ye kpɔa lãmetsiŋusẽ ƒe kɔsɔkɔsɔ sia dzi. Eyae nye be ne T3 kple T4 ƒe agbɔsɔsɔ le ʋua me dzi ɖe edzi la, eyia hypothalamus kple pituitary gbɔ hegblɔna be, "Enyo, esɔ gbɔ, dzudzɔ TRH kple TSH wɔwɔ." Ne T3 kple T4 ƒe agbɔsɔsɔ dzi ɖe kpɔtɔ la, dɔ sia gadzea egɔme ake. Aleae míate ŋu ana thyroid hormone ƒe agbɔsɔsɔ si le míaƒe ŋutilã me nanɔ agbɔsɔsɔ aɖe me.

Bu eŋu abe AC ​​si le wò aƒeme ene. Ne vuvɔ le xɔa me la, AC la tsina, eye ne xɔa me xɔ dzo la, eʋuna.

Gake ne kuxi aɖe le hypothalamus, pituitary gland, alo thyroid gland ŋu la, lãmetsiŋusẽ siwo dome T3 kple T4 hã le ƒe dadasɔ ate ŋu agblẽ.

Nukae thyroid lãmetsiwo wɔna ɖe míaƒe ŋutilã ŋu? Alo, woƒe akpa si wowɔna!

Ne T4 do le ʋuka me vɔ la, lãmenugbagbevi aɖewo siwo le míaƒe ŋutilã me trɔnɛ wòzua T3. Woyɔa nuwɔna sia be de-iodination (iodine ɖeɖeɖa). Esia le alea elabena lãmenugbagbevi siwo dzi lãkusi me lãmetsiŋusẽwo gblẽa nu le la ate ŋu azã T3 nyuie wu T4. Esia tae míebua T4 be enye lãmetsi si mewɔa dɔ o eye T3 be enye lãmetsi si wɔa dɔ ɖo.

Lãmetsiwo, lãkusiwo, ŋutinuwo, kple ɖoɖo siwo ate ŋu atrɔ T4 wòazu T3e nye:

• Aklã
• Ayikuwo
• Lãmetsiwo
• Lãmetsiŋusẽ ƒe lãkusi `(Thyroid)`
• Pituitary gland ƒe lãkusi
• Brown adipose tissue (ami sia kpena ɖe ame ƒe ŋutilã ƒe dzoxɔxɔ ŋu le vuvɔ me)
• Titina lãmekawo ƒe dɔwɔwɔ

Eyata, T3 kple T4 lãmetsi siawo kpɔa ŋusẽ ɖe lãmenugbagbevi kple ŋutinu ɖesiaɖe si le míaƒe ŋutilã me dzi. Aleke wokpɔa ŋusẽ ɖe edzii?

• Wò ŋutilã kpɔa ŋusẽ ɖe alesi wòzãa nuɖuɖumeŋusẽ (ŋusẽ) dzi. Woyɔa esia be wò lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe tsɔtsɔme . Esia kpɔa ŋusẽ ɖe wò lolo dzi ɖeɖe kpɔtɔ alo dzi ɖeɖe kpɔtɔ dzi. Ame aɖewo gblɔna be aleke kee yewoɖaɖu nu o, yewomelolona o, gake ame bubuwo hã gblɔna be yewoƒe lolome dzina ɖe edzi ne yewoɖu nu vi aɖe gɔ̃ hã. Esia ate ŋu anye susuawo dometɔ ɖeka.
• Wò dzi ƒe tsotso dzi ɖena kpɔtɔna eye wòdzina ɖe edzi.
• Eɖea ŋutilã ƒe dzoxɔxɔ dzi kpɔtɔna eye wòdoa dzi. Ðeko ame aɖewo sena le wo ɖokui me be vuvɔ le yewo ŋu, gake ɖeko ame bubuwo sena le wo ɖokui me be fifia le yewo ƒom.
• Ekpɔa ŋusẽ ɖe alesi nuɖuɖu zɔna kabakaba to nuɖuɖumeŋusẽ me dzi.
• Ekpɔa ŋusẽ ɖe ahɔhɔ̃ ƒe tsitsi dzi (vevietɔ le ɖevime).
• Ekpɔa alesi lãmekawo ƒoa ƒui dzi.
• Eléa ŋutigbalẽ kple ƒuwo ɖe te. Eyae nye be ekpɔa alesi wowɔa lãmenugbagbevi yeyewoe be woatsɔ axɔ ɖe lãmenugbagbevi kukuwo teƒe dzi (esia sɔ).

Dodokpɔ kawoe wowɔna tsɔ léa ŋku ɖe ʋumenugbagbeviɣidɔ ƒe agbɔsɔsɔ ŋu?

Ʋudodokpɔ geɖe li siwo woate ŋu awɔ atsɔ akpɔ wò lãkusi ƒe agbɔsɔsɔ akpɔe ɖa be wò lãkusi le dɔ wɔm nyuie hã. Woyɔa esiawo zi geɖe be lãkusi ƒe dɔwɔwɔ dodokpɔ . Wo dometɔ vevitɔwoe nye:

• T4 dodokpɔ bliboa `(T4 dodokpɔ bliboa)`
• T4 (FT4) dodokpɔ femaxee
• T3 dodokpɔ bliboa `(T3 dodokpɔ bliboa)`
• T3 (Ft3) dodokpɔ femaxee
• Thyroid stimulating hormone dodokpɔ `(TSH dodokpɔ)`

Wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo hã, le kpɔɖeŋu me:

• Thyroid antibodies : Esiawo kpena ɖe ame ŋu wòkpɔa ʋumenugbagbeviɣidɔ vovovo siwo dɔlélenutsiŋutete hena vɛ.
• Thyroglobulin : Wozãa dodokpɔ sia tsɔ dea dzesi ʋumenugbagbeviɣidɔ eye woléa ŋku ɖe ʋumenugbagbeviɣidɔ ƒe atikewɔwɔ ŋu.

Dɔléle kawoe dzɔna ne thyroid lãmetsiwo mesɔ o?

Nɔnɔme geɖe li siwo tsoa thyroid lãmetsiwo ƒe agbɔsɔsɔ si mesɔ o gbɔ, alo wowɔa akpa aɖe le wo me. Thyroid dɔléle bɔ ŋutɔ. Wogblɔ be nyɔnuwo ate ŋu axɔ lãkusidɔ zi gbɔ zi atɔ̃ va ɖo enyi wu ŋutsuwo .

Lãmetsiŋusẽ ƒe dɔléle vevitɔwoe nye:

• Hypothyroidism (underactive thyroid) : Esia nye esime ŋutilãa mewɔa thyroid lãmetsi siwo sɔ o. Nusianu si le ŋutilãa me dzea dɔwɔwɔ gɔme vivivi.
• Hashimoto ƒe dɔléle : Esia nye dɔléle si ame ŋutɔ ƒe dɔlélenutsiŋutete wɔna. Esia fia be míaƒe ŋutilã ŋutɔ ƒe dɔlélenutsiŋutete dzea thyroid gland dzi. Esia hea ʋumenugbagbeviɣidɔ vɛ.
• Hyperthyroidism (overactive thyroid gland) : Esia nye esime thyroid gland la wɔa thyroid hormone geɖe akpa, si wɔnɛ be nusianu si le ŋutilãa me wɔa dɔ kabakaba akpa.
• Graves ƒe dɔléle : Esia hã nye dɔléle si tsoa dɔlélenutsiŋutete gbɔ si hea ʋumenugbagbeviɣidɔ si gbɔ eme vɛ.
• Thyroiditis (ʋumenugbagbeviɣidɔ/ʋuʋudedi) .
• Thyroid ƒe lãkusiwo .
• Goiter (thyroid gland ƒe lolome/kɔ ƒe vuvu).
• Lãmetsiŋusẽ me dɔdzẽ .

Èɖo ŋku esime míeƒo nu tso hypothalamus kple pituitary gland ŋua? Kuxi siwo le lãkusi mawo ŋu hã ate ŋu ana lãkusi me lãmetsiŋusẽ ƒe agbɔsɔsɔ natrɔ, elabena wokpena ɖe lãkusi me lãmetsiwo ŋu wòɖɔa ŋu ɖo.

Ɣekaɣie wòle be makpɔ ɖɔkta tso thyroid lãmetsiwo ŋu?

Zi geɖe la, ne thyroid hormone ƒe agbɔsɔsɔ mesɔ o la, edzena le dzesi siwo míekpɔna me. Thyroid lãmetsiwo kpɔa ŋusẽ ɖe míaƒe ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ kabakaba dzi. Eyata ne thyroid lãmetsiwo dzi ɖe edzi la, duƒuƒu dzina ɖe edzi wu alesi wòle, eye ne dzi ɖe kpɔtɔ , duƒuƒu dzi ɖena kpɔtɔna. Masɔmasɔ siawo ate ŋu ahe dzesiwo abe:

• Kpekpeme dzi ɖeɖe kpɔtɔ alo edzi ɖeɖe kpɔtɔ le susu aɖeke manɔmee.
• Dzi ƒe tsotso dzi ɖe kpɔtɔ alo dzi ɖe edzi.
• Vuvɔ alo dzoxɔxɔ ƒe ŋutete manɔamesi. (Le dukɔ abe Sri Lanka ene gɔ̃ hã me la, ne èse le ɖokuiwò me be vuvɔ/xɔ dzo etɔxɛe wu bubuwo.)
• Ŋutilã si ƒu alo tsi ƒe dzidziɖedzi.
• Dzinukpɔkpɔ si mebɔ o le nyɔnuwo me.
• Ðeɖi te eŋu ŋutɔ, alo dzimaɖitsitsi ko.
• Nɔnɔmewo abe dɔmeɖui alo aɖuɖɔtoe ene.
• Nuŋlɔɖi be, esesẽ be nàna wò susu nanɔ teƒe ɖeka.

Ne dzesi siawo le ŋuwò la, anyo wu be nàyi ɖɔkta gbɔ. Woate ŋu awɔ ʋudodokpɔ bɔbɔe aɖewo akpɔe ɖa be wò lãkusi me lãmetsiŋusẽ ƒe agbɔsɔsɔ megale dɔ wɔm nyuie o hã.

Mlɔeba la, nu ʋɛ aɖewo siwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Thyroid hormone nye lãmetsi vevi aɖe ŋutɔ si kpɔa ŋusẽ ɖe nu geɖe dzi le míaƒe ŋutilã me. Ɣeaɖewoɣi la, ate ŋu aɖiɖi akpa alo akɔ akpa le míaƒe ŋutilã me. Nya nyuiae nye be woate ŋu ada lãkusidɔ geɖe dzidzedzetɔe.

Ne dzesi siwo do ƒome kple lãkusi me lãmetsiwo le ŋuwò, alo ne èdi be yeanya ne afɔku aɖewo le ye ŋu si ana ʋumenugbagbeviɣidɔ aɖe nadze ye dzi la, mègavɔ̃ be yeaƒo nu kple yeƒe ɖɔkta o. Wole afima be yewoakpe ɖe ŋuwò. Beléle na wò ŋutilã kple enyanya ne kuxi aɖe li kabae nye mɔ nyuitɔ si dzi nàto anɔ agbe le lãmesẽ me.

` thyroid lãmetsi, thyroid lãmetsi, lãmenugbagbeviwo ƒe dɔwɔwɔ, hypothyroidism, hyperthyroidism, TSH, T3, T4