Nu kpata aɖe si vaa kansa dada me: Mina míasrɔ̃ nu tso Tumor Lysis Syndrome ŋu!

Agbenɔnɔ kple kansa nye avuwɔwɔ ŋutɔŋutɔ. Togbɔ be atikewɔmɔnuwo abe atikewɔmɔnu ene ate ŋu akpe ɖe kansadɔlékuiwo ƒe tsɔtsrɔ̃ ŋu hã la, ɣeaɖewoɣi la, dɔdamɔnu mawo ate ŋu ahe kuxi siwo womele mɔ kpɔm na o vɛ. Egbea la, míele nu ƒom tso nɔnɔme kpata aɖe si hiã be woakpɔ egbɔ enumake eye wòate ŋu ade ame ƒe agbe afɔku me gɔ̃ hã ŋu . Woyɔa esia be Tumor Lysis Syndrome.

Nukae nye Tumor Lysis Syndrome? Mina míase egɔme bɔbɔe.

Kpuie ko la, Tumor Lysis Syndrome nye nɔnɔme sesẽwo ƒe ƒuƒoƒo aɖe si dzɔna ne kansa lãmenugbagbevi gbogbo aɖewo ku zi ɖeka eye lãmenugbagbevi mawo me nuwo do ɖe ʋukawo me. Bu eŋu kpɔ, nɔnɔme sia ate ŋu adzɔ le gaƒoƒo ʋɛ aɖewo me tso esime wodze kansa dada gɔme. Ate ŋu adze egɔme kaba ŋutɔ eye wòazu nɔnɔme si hiã be woawɔ atike na ame kpata. Eyata ɖɔktawo le ŋku lém ɖe esia ŋu ɣesiaɣi.

Gake nya nyui aɖe li. Mɔ siwo dzi woato axe mɔ na Tumor Lysis Syndrome ƒe dzɔdzɔ le ɖɔktawo si . Wowɔa esia to dzesidede amesiwo le afɔku gã me kple afɔɖeɖewo wɔwɔ be woaɖe afɔku ma dzi akpɔtɔ me.

Nukae dzɔna ɖe míaƒe ŋutilã dzi le nɔnɔme sia me?

Ne kansa lãmenugbagbeviwo do go nuteɖeamedzi, vevietɔ tso atikewɔwɔ abe atikewɔmɔnu ene me la, wogblẽna. Emegbe, kasia atike kple aɖi siwo le lãmenugbagbevi mawo me la ƒoa ƒu ɖe ʋua me le agbɔsɔsɔ gã aɖe me. Kuxia dzea egɔme ne míaƒe ŋutilã mete ŋu ɖe nusiawo ɖa kaba o. Míaƒe dzi, ayiku, kple lãmekawo koŋ ate ŋu agblẽ nu le tumor lysis syndrome sia ŋu. Na míakpɔ nusiwo gblẽa nu le ame ŋu siawo ɖa:

• Hyperuricemia - Esia fia be uric acid ƒe agbɔsɔsɔ dzina ɖe edzi: Ne uric acid si le ʋu me dzi ɖe edzi la, ate ŋu age ɖe ayiku me, si ana ayiku nawɔ dɔ nyuie o eye ayiku gɔ̃ hã nawɔ dɔ nyuie. Bu eŋu abe tsi ƒe pɔmpi me tsi ene.
• Hyperphosphatemia - si fia be phosphorus ƒe agbɔsɔsɔ si dzi ɖe edzi: Phosphorus ƒe agbɔsɔsɔ si dzi ɖe edzi le ʋu me hã doa kplamatse ayiku ƒe dɔwɔwɔ.
• Hyperkalemia - Esia fia be potassium sɔ gbɔ: Ne potassium sɔ gbɔ la, àte ŋu akpɔ dzesiwo abe ʋuʋudedi, ʋuʋudedi, kple aɖuɖɔtoe ene. Menye ema ɖeɖeko o, ke wò dzi ƒe tsotso ate ŋu atrɔ, si ana be dzi ƒe tsotso natsi dzimaɖi, eye ɖewohĩ dzidɔ gɔ̃ hã nadze dziwò. Esia nye afɔku vie, alo?
• Uremia: Esia dzɔna ne ayikuawo dzudzɔ aɖiwo ɖeɖe le ʋua me. Uremia ate ŋu ahe kuxi sesẽwo vɛ na ƒuwo, lãmekawo, dzitodzitowo, kple ʋukawo.
• Hypocalcemia - Calcium ƒe agbɔsɔsɔ si bɔbɔ: Calcium ƒe agbɔsɔsɔ si bɔbɔ ɖe ʋu me ateŋu ahe tɔtrɔ vɛ le dzi ƒe tsotso me, lãmekawo ƒe ʋuʋu, tɔtɔ, lãmetutudɔ kple abɔ kple afɔwo ƒe ʋuʋu. Ɣeaɖewoɣi la, dzi ƒe dɔmawɔmawɔ nyuie gɔ̃ hã ate ŋu aku.

Nu vevitɔ kekeake: Tumor Lysis Syndrome dzɔna ne nɔnɔme siawo dometɔ ɖeka alo esi wu nenema va kpe ta.

Ðe Tumor Lysis Syndrome nye nusi dzɔ kpataa?

Ẽ, keŋkeŋ! Tumor Lysis Syndrome nye atikewɔwɔ kpata si hiã be woawɔ atike nɛ enumake. Eyata ele vevie ŋutɔ be míanya esia.

Amekae ate ŋu adze nɔnɔme sia me?

Menye amesiame si wodoa kansa na lae xɔa Tumor Lysis Syndrome o. Ne èle kansa ƒe atike wɔm la, anyo be nàbia wò ɖɔkta tso esia ŋu. Le goawo katã me la, amesiwo xɔa atike na kansa ƒomevi siwo gbɔna la ate ŋu axɔ dɔléle sia:

• Ʋumenugbagbeviɣidɔ Sesẽ
• Aggressive Non-Hodgkin’s Lymphoma, abe Burkitt ƒe Ʋumenugbagbeviɣidɔ kple Diffuse Large B-cell Lymphoma ene
• Ʋumenugbagbeviɣidɔ (AML) .
• B-cell Acute Lymphoblastic Leukemia (ALL) ƒe Ʋumenugbagbeviɣidɔ (ALL) .
• Lãmenugbagbevi Suewo ƒe Aklãdɔléle

Azɔ hã, kansa ƒomevi bubu aɖewo li siwo ne woda wo la, afɔku si le wo me be woaxɔ nɔnɔme sia dzi ɖena kpɔtɔna vie. Gake medzo keŋkeŋ o. Kpɔɖeŋuwo:

• Anaplastic Large Cell Lymphoma - Esia nye dɔlélenutsiŋutete ƒe kansa si mebɔ o, si tsina blewu.
• Ʋumenugbagbeviɣidɔ si Nɔa Anyi Didi (CLL) .
• Ahɔhɔ̃mekawo ƒe dɔléle
• No me Dɔdzẽ
• Lãmetsi Falɛfalɛwo ƒe Sarcoma
• Medulloblastoma ƒe dɔléle
• Merkel Lãmenugbagbeviwo ƒe Dɔdzẽ

Nukae nye nu bubu siwo gbɔ Tumor Lysis Syndrome tsona?

Ðɔktawo nya be ame aɖewo le afɔku gã aɖe me be woaxɔ dɔléle sia. Woɖɔa ŋu ɖo etɔxɛe hafi wonaa atikewɔmɔnu ame mawo. Nusiwo nana afɔkua dzina ɖe edzi dometɔ aɖewoe nye esi:

• Ʋumenugbagbevi ɣiwo ƒe xexlẽme si sɔ gbɔ ŋutɔ ƒe amesinɔnɔ.
• Uric acid ƒe agbɔsɔsɔ le ʋua me sɔ gbɔ xoxo.
• Ayikukuxiwo ƒe amesinɔnɔ.
• Tsi si le ŋutilã me dzi ɖe kpɔtɔ (Dehydration).
• Kansa ƒe amesinɔnɔ le eƒe akpa si nu sẽ ŋutɔ (Later-stage Cancer).
• Dɔdzẽ gãwo ƒe amesinɔnɔ.

Ðe nɔnɔme sia ate ŋu adzɔ ne womewɔ atike na ame oa?

Ẽ, gake ƒã hafi wòdzɔna . Ne edzɔ la, ɖɔktawo yɔnɛ be Spontaneous Tumor Lysis Syndrome.

Nukae nye Tumor Lysis Syndrome ƒe dzesiwo?

Zi geɖe la, dzesi siawo dzena le gaƒoƒo 12 va ɖo 72 me tso esime wodze atikewɔmɔnu zazã gɔme. Nusiwo wonye enye si:

• Aɖuɖɔtoe kple ʋuʋudedi.
• Dɔmetɔtrɔ.
• Tɔtrɔ le aɖuɖɔ agbɔsɔsɔme si nèɖena ŋu (ate ŋu adzi ɖe edzi alo aɖiɖi).
• Gbɔdzɔgbɔdzɔ Kple Kuviawɔwɔ.
• Ʋu si le aɖuɖɔ me (Hematuria).
• Asrã ƒe nɔnɔmewo, si fia be alɔ̃madɔmadɔ.
• Lãmetsiwo ƒe Ʋuʋudedi.
• Syncope ƒe dɔléle.
• Dzi ƒe tsotso si mesɔ o.
• Ʋu ƒe sisi le lãme na ame (Hypotension).
• Ƒunukpeƒe Vevesese.

Ne èkpɔ dzesi siawo dometɔ ɖeka alo esi wu nenema esime nèle kansa dam la, ele be nàna ɖɔkta nanya enumake.

Nukatae Tumor Lysis Syndrome dzɔna?

Kpuie ko la, nɔnɔme sia dzɔna ne kansa dada na kansa lãmenugbagbevi gbogbo aɖewo ku kpata kabakaba. Nu siwo le lãmenugbagbevi siwo le kukum la me (abe potassium, phosphorus, kple uric acid ene) ƒoa ƒu ɖe ʋua me zi ɖeka.

Zi geɖe la, míaƒe ayikuwoe ɖea nu siawo siwo míedi o la ɖa. Gake, ne lãmenugbagbevi gbogbo aɖewo ku zi ɖeka la, ayikuawo mate ŋu awɔ dɔ sia o. Ele abe tsidzɔƒe aɖe si xe ne gbeɖuɖɔ gbogbo aɖe ge ɖe eme zi ɖeka ene. Emegbe aɖi siawo tea ƒoƒo ɖe ŋutilãa me.

Aleke ɖɔktawo wɔa dea dzesi dɔléle siae?

Ðɔktawo ƒe susu vevitɔe nye mɔxexe ɖe Tumor Lysis Syndrome nu. Be woate ŋu awɔ esia la, woawɔ ʋu kple aɖuɖɔ dodokpɔ edziedzi be woakpɔe ɖa be wò ayikuwo le dɔ wɔm nyuie eye wole aɖiwo ɖem le wò ŋutilã me hã.

Nukawoe nye Tumor Lysis Syndrome ƒe atikewo?

Agbagba gbãtɔ si ɖɔktawo dzenae nye be yewoaxe mɔ ɖe esia nu. Wowɔa esia to dzesidede amesiwo le afɔku gã me kple afɔɖeɖe tɔxɛwo wɔwɔ ɖe wo ŋu me. Gake, ne nɔnɔmea do mo ɖa la, wodzea atikewɔwɔ gɔme enumake.

Nusiwo woawɔ atsɔ axe mɔ ɖe enu:

• Tsidede ʋuka me (IV): Esia kpena ɖe ame ŋu be tsi nyui nanɔ ame ŋu, edoa aɖuɖɔ ɖe ŋgɔ, eye wòkpena ɖe ame ŋu wòɖea aɖinuwo ɖa le ŋutilãa me kaba.
• Atike siwo xea mɔ na uric acid ƒe kristalo ƒe gege ɖe ayiku me nana: Atike aɖewo li siwo kpena ɖe ame ŋu be woaɖu uric acid ƒe agbɔsɔsɔ dzi.

Atikewɔwɔ ne nɔnɔmea do mo ɖa:

• Aɖuɖɔtoemetikewo nana: Esia kpena ɖe ame ŋu wòɖea aɖinuwo ɖa le ŋutilãa me kabakaba.
• GLISH: Atike siwo ɖea potassium kple phosphorus si sɔ gbɔ la nana.
• Atike siwo nana uric acid kristalo siwo ƒo ƒu ɖe ayiku me.
• Dialysis: Ne wò ayikuwo mele dɔ wɔm nyuie o la, ɖewohĩ ahiã be nàdi dialysis be woaɖe aɖinuwo ɖa le wò ʋu me. Esia le abe wò ayiku ƒe dɔwo wɔwɔ le mɔ si wowɔ kple asi nu ene.

Ðe woate ŋu ada Tumor Lysis Syndromea?

Ẽ, keŋkeŋ! Ame 90 kloe le alafa me siwo ŋu dɔléle sia le la hayana. Nu vevitɔe nye be nànya dɔlélea kaba eye nàdze edada gɔme kaba.

Nukae dzɔna ne woda nɔnɔme sia vɔ?

Tumor Lysis Syndrome ate ŋu agblẽ nu le wò ayiku ŋu vie. Eyata ne dɔléle sia le ŋuwò la, ele vevie ŋutɔ be nàbia wò ɖɔkta nenye be ehiã be nàgawɔ atike na wò alo beléle tɔxɛ na wò vaseɖe esime wò ayikuwo nahaya.

Kansadɔdamɔnuawo le nyonyom ɖe edzi gbesiagbe, si wɔe be míete ŋu tsrɔ̃a kansadɔlékuiwo kabakaba. Gake ɣeaɖewoɣi la, ne lãmenugbagbevi siawo ku la, atike kple aɖi siwo woɖena ɖe go ate ŋu ahe nɔnɔme si me afɔku le si woyɔna be Tumor Lysis Syndrome vɛ. Esia ate ŋu akpɔ ŋusẽ gã aɖe ɖe dzi kple ayiku dzi.

Mlɔeba la, nusi dzi nàɖo ŋkui (Take-Home Message) .

Kansa dada nye kuxi sesẽ aɖe. Le ɣeyiɣi sia me la, ele vevie be nànɔ ŋudzɔ ɖe nɔnɔme kpatawo abe Tumor Lysis Syndrome ene ŋu. Ne wole kansa dam na wò la, kpɔ egbɔ be yebia yeƒe ɖɔkta nenye be nɔnɔme sia ate ŋu adze ye dzi. Woaɖe afɔku siwo le eme la me na wò eye woawɔ nusianu si woate ŋui atsɔ axe mɔ ɖe nɔnɔme sia nu alo adae ne edzɔ. Mègaŋe aɖaba ƒu dzesi aɖeke dzi o, eye nàgblɔe na ɖɔkta enumake ne ède dzesi nane si mebɔ o. Wò lãmesẽ dzi kpɔkpɔe nye nu vevitɔ kekeake!

` Tumor lysis syndrome, kansa dada, atikewɔmɔnu, ayikudɔ, hyperkalemia, hyperuricemia, atikewɔwɔ kpata