Migraine is not just a headache, as anyone who suffers from it knows. The severe pain that comes with it, nausea, inability to look at light, sometimes being unable to do anything useful and having to stay in bed all day... There are times when life becomes boring with all this. If you also suffer from these frequent migraines that cannot be controlled with ordinary painkillers, this article will be very important for you. Today we are talking about a modern type of injection used to prevent migraines. That is Fremanezumab.
What is Fremanezumab (AJOVY)?
Simply put, Fremanezumab is a specific medication used to prevent migraines. It is most commonly known by the brand name AJOVY .
This is not like a regular pill. This belongs to a class of drugs called `(Monoclonal Antibody)`. Think of it as a small missile in our body that hits its target. Similarly, this medicine also targets a specific chemical (`(Calcitonin Gene-Related Peptide or CGRP)`) that is involved in the onset of migraines and blocks its action. This helps greatly in reducing the frequency and severity of migraines.
The important thing is, this is not a medicine to take after a migraine has started. It is used to prevent migraines. That is, taking this injection when you already have a headache will not reduce the pain at that moment.
Things to tell your doctor before using this medicine
It is very important to inform your doctor about your complete health condition before starting this treatment. Be sure to tell them about these things in particular.
- Allergies: If you have any allergies to Fremanezumab or any other medicine, food, or dye, you must tell us about it.
- Pregnancy: If you are pregnant or planning to become pregnant, tell your doctor.
- If you are a breastfeeding mother: If you are a breastfeeding mother, be sure to inform your child about that as well.
Based on this information, the doctor will decide whether this treatment is suitable for you or not.
How to use the vaccine?
This is a subcutaneous injection. It is usually given in the abdomen, thigh, or upper arm. Most often, the vaccine comes in a pre-filled syringe or auto-injector so you can inject yourself at home.
Don't be afraid. The first time, the doctor or nurse will clearly show you how to do this correctly.
- Get the vaccine on time: Get the vaccine at the right intervals (for example, once a month or every three months) as your doctor tells you. Don't get the vaccine too often.
- Dispose of used needles properly: This is very important. Never throw used needles in the trash. You can get a special container (`(sharps container)`) from the hospital. If there is no such container, ask your doctor how to get one. This will protect you and others from harm.
- For children: If this medicine is given to children, special care should be taken by talking to a pediatrician about it.
What if I miss a vaccination?
If you miss a dose, get it as soon as possible. However, if it is only a few days until your next dose, skip the missed dose and get the next dose on the scheduled day. Never take a double dose. If you are unsure, ask your doctor.
What if I take too much medicine?
If you think you have taken too much medicine by mistake, immediately call the National Poisons Information Centre at the Colombo National Hospital or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What are the possible side effects of this medicine?
Like any medicine, Fremanezumab can cause some side effects. However, most people do not experience serious side effects. The table below provides a clearer picture of this.
| Type of side effect | What you need to know |
|---|---|
| Serious side effects that should be reported to the doctor immediately | |
| Severe Allergic Reactions |
If you experience any of these symptoms, seek medical advice immediately as it may be an emergency. |
| Side effects that are usually nothing to worry about, but should be reported to your doctor if they persist | |
| Injection site reactions | Redness, mild pain, itching, or swelling at the injection site. This is very common. This usually goes away in a day or two. But if it persists or gets worse, tell your doctor. |
Are there any problems with other medications?
Because Fremanezumab is a highly targeted treatment, the likelihood of serious interactions with other medications is low, as has been found so far.
However, don't hide from your doctor about other medications you are taking. Give your doctor a complete list of all other medications (including those for other conditions), vitamins, herbal remedies, and nutritional supplements you are taking. It is also important to tell your doctor if you smoke or drink alcohol.
How to store the medicine?
You will receive instructions from the hospital on how to store this vaccine. Usually, it is said to be stored in the fridge at a specific temperature. Never store it in the freezer. Keep it out of the reach of children. Do not use it for any reason after the expiration date on the label.
If your migraine symptoms do not improve, or if they get worse, be sure to see your doctor again.
Take-Home Message
- Fremanezumab (AJOVY) is not a painkiller taken after a migraine attack. It is a new injectable treatment used to prevent migraine attacks .
- A doctor will decide if this treatment is right for you, so talk to your doctor about this openly.
- Follow the doctor's instructions regarding the method of using the vaccine, the correct dosage, and the timing.
- If you experience severe allergic symptoms, such as facial swelling or difficulty breathing, it is an emergency. Seek immediate medical attention.
- Dispose of used needles safely, in a sharps container only.
- Give your doctor a complete description of all other medications you are taking and your health conditions.
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