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✓ Medically reviewed by Dr. Priya Sammani (MBBS, PG Dip. FM) | Age — · M/F · BMI —
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🩺 Pregnancy & Maternal

Do you also experience excessive thirst during pregnancy? Let's talk about this rare condition (Gestagenic Diabetes Insipidus)

Dr. Priya Sammani (MBBS)

Medically reviewed by Dr. Priya Sammani (MBBS) — Updated on Jul 7, 2026 · 6 min read

Do you also experience excessive thirst during pregnancy? Let's talk about this rare condition (Gestagenic Diabetes Insipidus)
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We all know that it is normal to have to go to the bathroom frequently during pregnancy, especially in the last few months. This is because of the pressure that the baby puts on the bladder as it grows. But if you are unbearably thirsty, if you feel like you are drinking bottles of water a day and you are not getting enough, if you are having to go to the bathroom every two hours, then this may be something different from a normal pregnancy. This is a rare condition called Gestagenic Diabetes Insipidus that we are talking about today. Although it has Diabetes in its name, this is not the diabetes mellitus that we all know. This is a completely different condition.

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Why is this happening? What is the reason?

Simply put, this is a very rare condition. During pregnancy, your placenta sometimes produces an enzyme. This enzyme can destroy a hormone in our body called vasopressin.

Think of it this way, this vasopressin hormone is like a manager who controls the water in our body. It is the one who tells our kidneys, "Okay, now the body has enough water, keep some, and excrete the rest as urine." So when this vasopressin hormone is destroyed by that enzyme from the placenta, the body's water control becomes disrupted. Then the kidneys can't retain the required amount of water in the body, and they start excreting urine continuously.

This results in you feeling extremely thirsty and needing to urinate frequently . For some people, this condition can lead to incontinence and bedwetting at night.

Very rarely, this condition can be hereditary. Sometimes it can be caused by a problem with the body's thirst control mechanism. But most of the time, it's difficult to find a specific cause.

What exactly are the symptoms?

It's normal to need to go to the bathroom at night during pregnancy. But in this case, it's different. See if you have these symptoms at the same time.

Symptom Description
Excessive thirst (Polyuria) This is not a normal thirst for water. It is an unbearable thirst that feels like it is not enough no matter how much water you drink. You are tempted to drink liters of water a day.
Frequent urination (Polydipsia) You need to go to the bathroom several times an hour. You also pass a lot of urine. The color of your urine is often clear and diluted, like water.
Other features Excessive water loss from the body can cause nausea, dizziness, and a feeling of weakness.

The important thing is that these symptoms are not one or two, but several together. If you have both excessive thirst and excessive urination, you should be concerned.

How is this diagnosed and treated?

When you tell your doctor about these symptoms, he or she will run several tests to confirm the condition.

  • Urine tests: A sample of your urine is tested to see how diluted it is, meaning it's watery, or whether it's concentrated and yellow in color.
  • Blood tests: Blood tests may also be done to check things like blood sodium levels.

Treatment methods

Once this condition is diagnosed, the treatment varies depending on the severity of the symptoms.

1. Observation without treatment: Sometimes, if the symptoms are not too severe, the doctor may decide not to do any special treatment. However, if this happens, you will be checked regularly. Your body will be carefully monitored to ensure that you are properly hydrated. You will need to keep a bottle of water nearby at all times , as it is essential to prevent dehydration.

2. Medication: If your symptoms are severe, you may be given a medication called desmopressin . This is a synthetic form of the hormone vasopressin that we talked about earlier. It usually comes as a nasal spray. This medication works by replacing the function of the destroyed hormone, helping the kidneys reabsorb water, and controlling urine output. It can also help control things like bedwetting at night.

When should I see a doctor?

This is the most important part. If you are pregnant and have all of the following symptoms together, never ignore it as something normal.

  • If you need to go to the bathroom frequently , especially at night.
  • If you feel unbearably thirsty .
  • If you drink a lot more water than you normally drink in a day.

If you have all three of these symptoms together, please see your doctor and explain this clearly. There is no need to panic. This is a manageable condition.

The good news is that for most women, this condition goes away completely within 4 to 6 weeks after giving birth. However, there is a chance that this condition will recur in future pregnancies.

💡 Take-Home Message

  • Gestagenic Diabetes Insipidus is a rare condition that occurs during pregnancy. It is not diabetes mellitus.
  • The main reason for this is that an enzyme produced by the placenta destroys the hormone vasopressin, which controls water in the body.
  • The main symptoms are unbearable thirst and excessive urination.
  • If you are pregnant and have these symptoms together, don't assume it's normal and definitely see your doctor.
  • This condition can be managed well with treatment and usually resolves completely after the baby is born.
Pregnancy, Excessive Thirst, Frequent Urination, Gestagenic Diabetes Insipidus, Placenta, Vasopressin, Desmopressin

❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

Why is this happening? What is the reason?

Simply put, this is a very rare condition. During pregnancy, your placenta sometimes produces an enzyme. This enzyme can destroy a hormone in our body called vasopressin. Think of it this way, this vasopressin hormone is like a manager who controls the water in our body. It is the one who tells our kidneys, "Okay, now the body has.

What exactly are the symptoms?

It's normal to need to go to the bathroom at night during pregnancy. But in this case, it's different. See if you have these symptoms at the same time.

How is this diagnosed and treated?

When you tell your doctor about these symptoms, he or she will run several tests to confirm the condition. Key points include: Urine tests: A sample of your urine is tested to see how diluted it is, meaning it's watery, or whether it's concentrated and yellow in color.; Blood tests: Blood tests may also be done to check things like.

How is it treated (Treatment methods)?

Once this condition is diagnosed, the treatment varies depending on the severity of the symptoms. 1. Observation without treatment: Sometimes, if the symptoms are not too severe, the doctor may decide not to do any special treatment. However, if this happens, you will be checked regularly. Your body will be carefully monitored to.

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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.