Has your doctor prescribed Pretomanid for you or someone in your family to treat tuberculosis? So today we will talk briefly about this medicine, how to use it, and what to be careful about. Since this is a somewhat special medicine, it is very important for your well-being to know exactly what it is.
What is this medicine called Pretomanid?
Simply put, Pretomanid is a powerful medicine that treats tuberculosis (TB) infection in your lungs. Tuberculosis is a serious infection caused by bacteria. So what this medicine does is kill the bacteria that cause it and make you well.
This medicine is often not given alone. Doctors prescribe it in combination with one or two other medicines to get the best results when treating tuberculosis. Therefore, it is essential to take every medicine your doctor prescribes exactly as directed.
Things you need to tell your doctor before starting medication
Before starting this medication, it is very important to give your doctor a complete description of your health condition. Because that information will determine whether this medication is suitable for you or not, or what things you need to be more careful about. Be sure to tell them these things in particular.
- Liver disease: Be sure to mention if you have any pre-existing liver disease.
- Allergies: If you have any allergies, whether to Pretomanid, any other medication, food, or dyes, please let us know.
- Pregnancy and breastfeeding: It is essential to inform your doctor if you are pregnant, trying to become pregnant, or breastfeeding.
How should I use the medicine?
To get the most out of this medicine, you need to know how to use it correctly.
- You should take this pill with a glass of water.
- The most important thing is to always take this medicine with a meal. Do not take it on an empty stomach. Taking it with food helps the medicine absorb better and reduces stomach upset.
- Do not break, crush, or chew the tablet. Swallow it whole.
- Take the medicine every day, at the prescribed time and at the prescribed intervals, as prescribed by the doctor.
- Do not stop taking the medicine halfway, thinking that you are now cured. To be completely cured of tuberculosis, you must take the full dose of medicine prescribed by your doctor for the full duration. Otherwise, the disease may become severe again and become difficult to control.
- When you get this medicine from the pharmacy, you will receive a special instruction leaflet (MedGuide). Always read it carefully. It also contains important information.
What if I take too much medicine?
If you think you have taken too much of this medicine, do not take it lightly. If this happens , immediately call the National Poisons Information Centre at the Colombo National Hospital, or go to the Emergency Department (ETU) of the nearest hospital.
What to do if you miss a dose of medicine?
Anyone can forget. If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take two doses at once.
Other things that may interact with this medicine
Some medications and other things can interact with Pretomanid and affect its effectiveness, so be especially careful with these things.
- Alcohol
- Efavirenz (a medicine for HIV infection)
- Methotrexate (a medicine used for cancer and other diseases)
- Rifampin (another drug used to treat tuberculosis)
This list is just a few examples. So tell your doctor about all the medications you take (including vitamins, herbal remedies, and supplements), if you smoke, and if you drink alcohol. It's very important for your safety.
Possible side effects while taking the medicine
Like any medicine, Pretomanid can cause some side effects. Some of these can be serious, so it's important to be aware of them. Let's break these down into two categories.
| Side effect | Description and what to do |
|---|---|
| Serious side effects that require immediate medical attention | |
| Allergic Reactions | Skin rash, severe itching, swelling of the face, lips, or tongue. If any of these occur, see a doctor immediately. |
| Symptoms of Liver Injury | Yellowing of the eyes or skin, dark yellow/brown urine, light-colored stools, loss of appetite, pain in the upper right side of the stomach, and feeling lethargic. |
| Coughing up blood | If you cough up blood or phlegm, it could be a serious sign. Tell a doctor immediately. |
| Symptoms of Low Blood Sugar | Restlessness, dizziness, excessive sweating, body tremors, excessive hunger, blurred vision, and rapid heartbeat. |
| Other signs of infection | Fever, chills, persistent cough, sore throat, pain when urinating. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Digestive system problems | Nausea, vomiting, stomach pain, diarrhea, constipation. |
| Other pains | Back pain, joint pain, muscle pain, headache. |
| Other minor features | Loss of appetite, changes in taste, chest pain or tightness, insomnia. |
If you notice anything unusual that is not on this list, talk to your doctor about it too.
How should I store the medicine?
- Keep this medicine safely out of the reach and sight of children .
- Store in a dry place below 30°C (86°F).
- Keep the medicine in the original bottle or packet it came in.
- Discard expired medication without using it.
Take-Home Message
- Pretomanid is a powerful medicine for tuberculosis (TB). It must be taken exactly as prescribed by the doctor, for the full duration of the course.
- Always take this medicine with a meal. Swallow the tablet whole, without breaking, crushing, or chewing it.
- If you have liver disease, allergies, are pregnant, or are a breastfeeding mother, tell your doctor before starting the medication.
- If you experience any serious side effects, such as signs of liver damage (yellowing of the eyes, dark urine), or severe allergic reactions, seek medical advice immediately.
- Don't forget to tell your doctor about any other medications you take, and if you drink alcohol.
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