Have you ever looked at your urine and thought, “Hmm… this is foamier than usual”? Or do you sometimes have swelling in your hands and feet for no reason? Although we don’t pay much attention to these things, sometimes they can be important signals that our body is giving us. One such important signal is the release of protein in the urine , which is what we medically call `(Proteinuria)`. Let’s talk about this simply and kindly today.
What is proteinuria? (What is proteinuria?)
Simply put, proteinuria is an abnormally high amount of protein in your urine. Now you're probably thinking, "So what does that mean?"
Think of it this way: our kidneys are like a water filter, or a sieve. They clean our blood and remove waste products that are not needed by the body as urine. But they also filter out essential substances like proteins from the blood and put them back into the blood. That means healthy kidneys don't normally let proteins out.
However, if these kidneys are damaged by some kidney disease, it becomes as if the holes in the filter have become larger. Then, proteins such as albumin, which the body needs, start to be filtered from the blood and excreted in the urine. In many cases, there are no early symptoms of kidney disease, and the first sign that you may have protein in your urine is the appearance of protein in your urine. Most of the time, your doctor will first detect this during a urine test during a routine medical checkup .
Are there types of proteinuria?
Yes, this situation can be divided into three main types. To understand this clearly, see the table below.
| Proteinuria Type | Simple Description | Is it a concern? |
|---|---|---|
| Transient Proteinuria | This is the most common type. It comes and goes from time to time. It can be triggered by things like fever, excessive exercise, and stress. | Usually, there is nothing to worry about. This condition will go away on its own once the cause is gone. |
| Orthostatic Proteinuria | Protein is only excreted in the urine when you are standing, but not when you are sleeping. This is especially common in young people. | This is not a harmful condition either. It usually goes away on its own as you get older. |
| Persistent Proteinuria | This is a chronic condition that occurs due to underlying medical conditions such as kidney disease, diabetes, and high blood pressure. | This is the type we should be most concerned about. It could be a sign of a serious underlying condition. |
What are the symptoms of this condition?
Often, there are no symptoms in the early stages. That's why it's called a silent disease. But as the condition gets worse, you may notice symptoms like:
- Foamy urine: If it foams like soapy water, it is a major sign of high protein levels.
- Edema : Your hands, feet, stomach, and face swell. This is because proteins that help the body retain water are excreted in the urine.
- The need to urinate frequently.
- Difficulty breathing .
- Excessive fatigue in the body.
- The food is tasteless.
- Nausea and vomiting.
- Muscle cramps at night.
What are the causes of protein in the urine?
There are many reasons for this. Some are temporary and not serious. But some are definitely reasons we should be concerned about.
General and temporary causes
- Dehydration
- Fever
- Excessive exercise
- Severe stress
- Kidney stones
- Exposure to extreme cold
Serious reasons to be concerned
The main cause of this is diseases that damage the kidneys. Among them , diabetes and high blood pressure are the two most common conditions.
In addition, protein in the urine can also be caused by serious conditions such as:
- Immune system diseases (e.g. Lupus)
- Kidney inflammation `(Glomerulonephritis)`
- Multiple Myeloma, a type of blood cancer
- Preeclampsia, a condition that occurs in pregnant mothers
- Protein deposits in the body's organs (Amyloidosis)
- Ingestion of any poison. (In this case, immediately contact the National Poison Information Centre at the Colombo National Hospital .)
- Cardiovascular disease
- Kidney cancer
- Heart failure
How do you find this, Doctor?
So when you go to see a doctor, whether because of these symptoms or for any other reason, the first thing he or she will do is ask you about your symptoms and examine you. Then, if there is any doubt about the condition, he or she may order tests like these.
1. Urinalysis: This is the most basic and important test. A small strip of chemical substance is placed in the urine sample you provide and tested. If it changes color, it means that there is protein in the urine. It is also examined under a microscope to see if there are any other things like blood cells and bacteria.
2. Blood tests: These can measure how well your kidneys are working.
3. Scans: Scans like `(CT scan)` and `(Ultrasound)` can detect kidney stones, tumors, or other obstructions.
4. Kidney Biopsy: If there is a strong suspicion of kidney disease, the doctor may need to take a very small piece of tissue from the kidney and examine it under a microscope. This can help diagnose the disease with certainty.
How is it treated?
Treatment options depend on the underlying cause of protein in the urine.
The most important thing is to find the cause and treat it. It's not helpful to treat just the protein loss.
- If it is due to kidney disease: Proteinuria can be an early sign of chronic kidney disease. Therefore, it is very important to control the disease before the kidneys fail completely. For this, your doctor will recommend things like medications, diet, exercise, and weight loss. In some severe cases, dialysis may be required.
- If you have diabetes or high blood pressure: Your doctor will likely prescribe medication to control those conditions. Most often, these medications are called angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs). These drugs help control blood pressure and protect the kidneys.
- During pregnancy: If you have high blood pressure and protein in your urine during pregnancy, it could be a serious condition called ``Preeclampsia.`` But the good news is that this condition goes away within a few days or weeks after the baby is born. However, it is important to attend medical clinics regularly throughout your pregnancy to have your blood pressure and urine tested.
Does this decrease when you drink a lot of water?
This is a problem for many people. Actually, no. When you drink a lot of water, you urinate more. This can reduce the concentration of protein in the urine that comes out at one time. This means that the urine becomes diluted.
But this won't stop your kidneys from leaking protein. So the solution to the problem isn't just drinking water, it's finding and treating the cause of the problem.
Take-Home Message
- Don't ignore foamy urine or swelling in your body. It could be an early sign of kidney disease.
- Proteinuria is not a disease, but a symptom of another underlying condition.
- People with diabetes and high blood pressure should be especially careful about this. Keep your medical conditions under control.
- If you have any doubts about this, be sure to see your family doctor for advice.
- If you find the correct cause and treat it properly, you too can prevent kidney damage and live a healthy life.
Proteinuria, protein in urine, kidney disease, foamy urine, diabetes, high blood pressure, body swelling











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