Sometimes, after an operation or when you have a stomach ache, nausea and vomiting are very annoying, aren't they? At times like these, doctors prescribe various types of medications for us. One such type of medication is these rectal suppositories. So today, let's talk about a medicine for nausea.
What is this medicine called Trimethobenzamide?
Simply put, Trimethobenzamide is a medication that helps control nausea and vomiting after surgery. It is also used to treat nausea caused by stomach upset (stomach problems). You may have heard of this medication from your doctor under the brand name `Tigan`.
Important note: This medication is no longer available in countries like the United States. But you don't need to worry about that. Your doctor will determine the safest and most appropriate medication for your condition.
Things you need to tell your doctor before using this medicine
When talking to your doctor about this medication, be sure to mention any of the following conditions if you have them, as they are very important for your safety.
- If you have an allergic reaction to `Trimethobenzamide`, the numbing medicine `Benzocaine`, other medicines, foods, preservatives or dyes.
- If you have kidney disease.
- If you have liver disease.
- If you are pregnant, or are expecting a baby.
- If you are a breastfeeding mother.
Okay, how exactly do you use this?
This is not a medicine to take by mouth, it is to be placed in the rectum. So you have to be a little careful and know exactly how to do it. Don't worry, it's very simple.
1. Wash your hands first: Wash your hands thoroughly with soap before handling the medicine and after using it.
2. Remove the cover: Carefully peel off the small foil wrapping around the medicine capsule and discard.
3. Wet the tip: Wet the tip of the medicine capsule with cold water. This will make insertion easier.
4. Correct posture: Lie down on your back. Keep your bottom leg straight and bend your top leg towards your stomach. As if you are hugging a ball.
5. Insertion: Now lift your upper buttocks slightly, making sure that your rectum is visible. Then, slowly and gently push the pointed end of the capsule inwards until it is fully inserted into your rectum.
6. Wait a moment: After inserting the medicine, press your buttocks together for a few seconds.
7. Rest for 15 minutes: Stop coming out after taking the medicine, and stay in bed for about 15 minutes.
The most important thing is, do not use it more often or in more quantity than the doctor tells you to .
What if you give it to small children?
Doctors may sometimes recommend this medicine for children. However, it is not recommended for use in infants and very young children . Therefore, before giving this to a child, be sure to consult a pediatrician.
What to do if the medication dose increases?
If you think you have taken too much of this medicine, go to the nearest hospital Emergency Department (ETU) immediately. Or call the National Poisons Information Centre at the Colombo National Hospital for advice. Treat this as an emergency.
Also, remember, this medicine is for you only. Do not give it to anyone else, even if they have the same symptoms as you.
What if I miss a dose?
If you forget to take a dose, take that dose as soon as you remember. But if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Never take two doses at the same time.
Other things that may interact with this medicine
Some medications, foods, and habits can interact with this medication and cause problems, so it's important to be aware of this as well.
| Things that can cause problems | Examples |
|---|---|
| Don't use these with names. | Medicines in the class of drugs called `phenothiazines` (e.g. `chlorpromazine`, `prochlorperazine`, `thioridazine`). Your doctor will know about these. |
| These may also conflict (be careful) |
|
There may be other things that are not on this list that can cause problems. So tell your doctor about every medication, vitamin, and traditional medicine you take. Also, be sure to tell your doctor if you smoke or drink alcohol.
Things to be careful about when using the medicine
- This medicine may make you feel sleepy, dizzy, or have blurred vision . So, avoid doing activities that require alertness, such as driving or operating machinery, until you know exactly how this medicine affects you.
- Don't get up suddenly. Especially if you are elderly, get up slowly when you are sitting or lying down. This will reduce the risk of dizziness and falling.
- Avoid alcohol completely. Alcohol can increase the side effects of this medication.
- If your condition worsens instead of improving after taking this medicine, inform your doctor immediately.
What are the possible side effects?
Like any medicine, this one can cause side effects in some people. Some are serious, some are common.
| Classification of side effects | |
|---|---|
| Side effects that you should report to your doctor immediately | |
| |
| Side effects that should be reported to the doctor if they persist or are bothersome. | |
|
If you experience any other side effects not on this list, seek medical advice about that as well.
Where should I put this medicine?
- Keep out of reach of children .
- Store at room temperature (between 15 and 30 degrees Celsius). Protect from excessive heat or cold.
- Discard expired medication without using it.
Take-Home Message
- `Trimethobenzamide suppository` is a medicine for nausea and vomiting that is placed rectally, not taken orally.
- Always use only the prescribed dosage and frequency as advised by your doctor.
- It is essential to inform your doctor about all other medications you are taking and any other medical conditions you may have.
- Avoid driving as this medicine may cause drowsiness or dizziness. Avoid drinking alcohol completely.
- Seek immediate medical attention if you experience a serious side effect such as difficulty breathing, seizures, or severe allergic reaction.
- Overdose is an emergency. Go to a hospital emergency room (ETU) immediately or contact the National Poisons Information Center.


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