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Let's learn about Laughing Gas? What is it really? (Nitrous Oxide)

Dr. Priya Sammani (MBBS)
Medically Reviewed by Dr. Priya Sammani (MBBS) ✓ Medically Reviewed
📅 Updated: Nov 9, 2025 • ⏱ 7 min read • Editorial Policy
Let's learn about Laughing Gas? What is it really? (Nitrous Oxide)
Table of Contents ▾
It's normal to feel a little nervous and anxious when you're told you're going to the dentist or have to undergo a minor surgery, isn't it? One way doctors use to ease your fears and keep you calm is through ' laughing gas '. So today, let's talk about this in detail and simply.
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What exactly is laughing gas?

Simply put, it's called nitrous oxide in medical terms. It's a colorless, nonflammable, and slightly sweet-smelling gas. It's used in medical and dental procedures to calm you down (sedate), reduce anxiety, and help you relax. It's been used as an anesthetic since the 1800s. Today, it's usually given in a mixture with oxygen. It's one of the most widely used anesthetic gases in the world.
Just think, this is not only used in medicine, but it is also used in cans of whipped cream used in cooking and to increase engine speed in car races.
Despite the name 'Laughter Gas', not everyone will laugh when they inhale this. But some people may feel a slight smile and a sense of happiness.

What are the advantages of using this?

There are several reasons why doctors still use this for minor treatments.
  • Reduces fear and anxiety: This calms the patient and encourages them to cooperate with the treatment.
  • It's very easy to give: no needles are needed. You just put a small mask over your nose (or maybe both nose and mouth) and breathe through it.
  • Starts working quickly: You will start feeling its effects within 3-5 minutes of starting to inhale the gas.
  • The effect wears off quickly: you will be completely back to normal within 5-10 minutes after you stop giving the gas.
  • Safe for the patient: This gas delivery device has more than 12 safety features that ensure no problems occur.

What happens to your body when you take this?

When you inhale this gas, you won't go completely to sleep. That means you'll be able to hear what's going on around you and answer questions the doctor asks. It's designed to calm you down and increase your pain threshold. That means it doesn't completely eliminate pain, but it can make you more tolerable. However, for very painful procedures, a stronger anesthetic may be needed. Nitrous oxide is a depressant. When you inhale it, you may experience the following:
  • Happiness
  • A smile
  • Headache
  • Mild euphoria
  • Completely light.
Before the treatment, the doctor will ask you if you want to use it. Then, a plastic mask will be placed over your nose and you will be asked to breathe. For younger children, a small hood may be used that covers only the nose while the mouth is open. Sometimes, a scent may be added to help children get used to the mask. You may feel your arms and legs feel a little heavy. You may also feel a little numbness in your hands and feet. The mask will be removed when the treatment is over, and you will be back to normal within a few minutes. For younger children, 100% oxygen may be given for a short period of time after the gas is stopped, to help them recover more quickly.

What are the side effects and who should not use this?

Nitrous oxide is very safe when given under the supervision of a doctor. However, a very small number of people may experience some side effects. The most common side effects are headache and nausea. Young children may sometimes vomit or feel a little anxious. The good news is that these side effects only occur in a very small percentage of patients, about 5%. It is not known if there are any long-term side effects from taking it for occasional medical treatment. However, if you have to undergo treatment that requires this gas frequently, your doctor may tell you to take a vitamin B12 supplement. This is because nitrous oxide can inactivate an enzyme that helps our body absorb essential vitamins B12 and B9 (folate). This can cause conditions such as anemia .
Situations when you should avoid using nitrous oxide
Status Reason
The first 3 months of pregnancy Since vitamins B12 and B9 are essential for a child's growth, interfering with their absorption by the body can be harmful to the child.
Serious heart disease It can increase the level of homocysteine ​​in the blood, which can aggravate heart disease.
Pneumothorax, middle ear surgery, retinal surgery, etc. Air pressure in such confined areas of the body can become dangerously high.
Serious mental illnesses (e.g. schizophrenia ) are not suitable for people who already have such conditions, as this gas can cause hallucinations.
Children under 3 years of age (in frequent use) Although one-time use has been shown to be safe, there are warnings that frequent anesthesia may affect a child's brain development. Talk to your doctor about this.

The dangers of misuse for pleasure

This is very dangerous and wrong . Some people use this gas as a drug. These are called 'whippits' and are usually filled into a balloon or bag and inhaled. There are several reasons why this is very dangerous. Doctors give a mixture of 30% nitrous oxide and 70% oxygen. However, 'whippets', which are taken as a drug, contain 100% nitrous oxide . When inhaled directly, the amount of oxygen in the lungs is severely reduced, and a life-threatening condition called hypoxia can occur.

Long-term adverse effects of misuse

When under the influence of this gas, the body loses its balance . Therefore, the chances of falling and getting injured, and of having car accidents are very high. Therefore, never use something like this for fun .

💡 Take-Home Message

  • Nitrous oxide is a very safe gas that is used to calm you down under the supervision of a doctor.
  • The effect of this is temporary. Once you stop giving the gas , you will be back to normal within a few minutes.
  • Using it as a recreational drug is very dangerous . It can cause nerve damage, oxygen deprivation, and even death.
  • Before you are given this gas for any treatment, be sure to tell your doctor about any other medical conditions you have (especially heart disease, mental illness) and if you are pregnant.
  • If you have any questions about this, don't be afraid to talk to your doctor.
Laughing gas, nitrous oxide, dentist, dental sedation, surgery, anesthesia, anxiety, fear, side effects

❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

What are the advantages of using this?

Key points include: Reduces fear and anxiety: This calms the patient and encourages them to cooperate with the treatment.; It's very easy to give: no needles are needed. You just put a small mask over your nose (or maybe both nose and mouth) and breathe through it.; Starts working quickly: You will start feeling its effects within.

What happens to your body when you take this?

Key points include: Happiness; A smile; Headache; Mild euphoria.

What should you know about Long-term adverse effects of misuse?

Key points include: Memory loss; Numbness in the limbs and nerve damage; Depression; Weakened immune system.

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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.