He aha ka pilina ma waena o ka estrogen a me ke kanesa? E aʻo kākou e pili ana i nā maʻi kanesa e pili ana i ka Estrogen ma ke ʻano maʻalahi!

Aloha! Ua lohe paha ʻoe i ka hormone estrogen. Lohe pinepine mākou i kēia inoa e pili ana i ke olakino o nā wahine. Akā, ʻaʻole paha ʻoe i ʻike e hiki i ka estrogen ke hoʻopilikia i ka ulu ʻana o kekahi mau ʻano maʻi kanesa. ʻO ia ka mea a mākou e kamaʻilio ai i kēia lā, ma ke ʻano maʻalahi loa, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.

He aha ka estrogen? E hoʻomaopopo mua kākou!

I ka ʻōlelo maʻalahi, he kemika kūlohelohe ka estrogen a ko mākou kino e hana ai. Kāhea pū mākou iā ia he hormone. Hele kēia hormone estrogen ma o ko mākou koko i nā ʻāpana a me nā ʻiʻo ma loko o ko mākou kino.

Manaʻo ka poʻe he nui he mea i kaupalena ʻia ka estrogen i nā wahine. ʻO ka ʻoiaʻiʻo, ʻo nā ovaries, ʻo ia kekahi ʻāpana o ka ʻōnaehana hānau wahine, ka mea e hana i ka nui o ka hormone estrogen. Akā, ʻo ka mea kupanaha, ʻo kēlā me kēia kanaka, me ka nānā ʻole i ke kāne, hana i kekahi nui o ka estrogen i loko o ko lākou kino, me nā ʻiʻo umauma a me nā hunaola momona.

I nā wahine, hoʻokumu ʻia ka wā ʻōpiopio e ka hui pū ʻana o ka estrogen a me kekahi hormone wahine ʻē aʻe, ʻo ka progesterone. ʻO ia hoʻi nā mea e like me ka ulu ʻana o ka umauma a me ka ulu ʻana o ka lauoho pubic. ʻO ia hoʻi ka hormone estrogen e kaohi ana i ke kaʻina hana menstrual o kēlā me kēia mahina.

Eia nō naʻe, he kuleana koʻikoʻi ko ka hormone estrogen i nā kāne. Hoʻopilikia ia i ka ulu ʻana o ka lolo, ka hana moekolohe olakino, a me ka libido.

No laila, he aha nā maʻi kanesa e pili ana i ka estrogen?

I kēia manawa, e nānā kākou i kēia mau maʻi kanesa e hilinaʻi ana i ka estrogen. I kekahi manawa e lohe paha ʻoe iā lākou i kapa ʻia ʻo estrogen receptor-positive , hormone-dependent , hormone-positive , hormone receptor-positive , a i ʻole hormone-sensitive . ʻO kēlā me kēia ʻano, ua like ko lākou manaʻo.

I ka ʻōlelo maʻalahi, ʻo ia hoʻi ke kōkua nei ka hormone estrogen i nā hunaola kanesa e ulu, ʻo ia hoʻi, e ulu a laha. E like me ka mea kanu e pono ai ka wai, he mea nui ka hormone estrogen no kēia ʻano kanesa.

Aia kekahi mau ʻano maʻi kanesa e hilinaʻi nui ana i ka estrogen. ʻO nā mea nui:

• Ka maʻi ʻaʻai umauma
• Ka maʻi ʻōpū
• ʻO ke kanesa ʻōpū - Ua kapa ʻia hoʻi kēia ʻo ke kanesa endometrial.

Ke kumu maoli nei anei ka estrogen i ka maʻi kanesa? He mea huikau iki kēia, ʻeā?

He moʻolelo paʻakikī kēia. I kekahi manawa, ua kapa ʻia ka hormone estrogen he carcinogen. ʻO ia hoʻi, he hiki iā ia ke hoʻoulu i ka maʻi kanesa. Akā, pono kākou e hoʻomaopopo pehea e hana ai kēlā.

Aneane kēlā me kēia cell i loko o ko kākou kino he ʻano protein kūikawā i kapa ʻia he mau mea loaʻa hormone. Hele mai ka estrogen i loko o ko kākou koko a hoʻopaʻa i kēia mau mea loaʻa. He mea nui kēia no nā hana he nui i loko o ko kākou kino. I loko o nā cell olakino, kōkua ka estrogen i nā cell e hana maʻamau a ulu olakino.

Eia nō naʻe, no kekahi mau kumu, ke hui pū kekahi mau mea, hiki i nā ʻāpana olakino ke lilo i mau ʻāpana maʻi kanesa. I ia hihia, hoʻomaka ka estrogen e hana e like me ka hunaahi. ʻO ia hoʻi, kōkua ka estrogen i nā ʻāpana maʻi kanesa i hana mua ʻia e māhele koke, hoʻonui, a laha mai kekahi wahi a i kekahi wahi o ke kino.

No laila, ma kahi o ka ʻōlelo ʻana ʻo ka estrogen wale nō ke kumu o ka maʻi kanesa, ʻoi aku ka pololei o ka ʻōlelo ʻana ʻo ka estrogen, me ka hui pū ʻana me nā mea ʻē aʻe e kōkua ai i ka ulu ʻana o ka maʻi kanesa, e kōkua ana i ka ulu ʻana o kahi maʻi kanesa e kū nei .

He aha nā mea e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i nā maʻi kanesa e pili ana i ka estrogen e like me kēia?

Aia kekahi mau kumu e hoʻonui ai i ka pilikia o ka loaʻa ʻana o nā maʻi kanesa e hilinaʻi ana i ka estrogen i kekahi ʻano. E nānā kākou i ko lākou ʻano:

• ʻOi aku ke kiʻekiʻe o ka estrogen i loko o ke kino ma mua o ka maʻamau: Loaʻa i kekahi poʻe nā pae kiʻekiʻe o ka estrogen.
• Ke lawe nei i ka Hormone Replacement Therapy (HRT): He lāʻau lapaʻau kēia i hāʻawi pinepine ʻia e mālama i nā ʻeha kino (e like me nā ʻālohilohi wela, ka hou ʻana i ka pō) e kū mai ana ma hope o ka menopause. E noʻonoʻo ua kuhikuhi ʻia kou makuahine a ʻanakē paha e ke kauka i ka lāʻau hormone no kāna mau hōʻailona post-menopausal. ʻO ia ke ʻano o ka HRT.
• Momona: Ke piʻi aʻe ka momona o ke kino, hiki ke hoʻonui ʻia ka hana ʻana o ka estrogen.
• ʻO ka loaʻa ʻana o kahi maʻi i kapa ʻia ʻo Polycystic Ovary Syndrome (PCOS): Pili pū kēia me kahi hormonal imbalance.
• Ka hoʻohana ʻana o Diethylstilbestrol (DES): He estrogen synthetic kēia i hāʻawi ʻia i nā wahine hāpai e pale aku i nā hāʻule keiki mai 1938 a 1971. Inā ua hoʻohana ka makuahine i ka DES i kēia manawa, a inā paha ua hōʻike ʻia ka makuahine i ka DES i ka wā hāpai a hānau i kahi keiki, aia ke keiki i ka pilikia o ka loaʻa ʻana o kēia ʻano maʻi kanesa ma hope o ke ola.

He aha ka pilina ma waena o ka estrogen a me ka maʻi ʻaʻai umauma?

I ka wā e pili ana i ka maʻi ʻaʻai umauma, ʻewalu o loko o nā maʻi ʻaʻai umauma he hormone receptor-positive . I ka ʻōlelo maʻalahi, pono kēia mau maʻi ʻaʻai i ka estrogen, progesterone, a i ʻole kēia mau hormones ʻelua e ulu.

Hoʻonui ʻia ka pilikia o ka maʻi ʻaʻai umauma me ka hoʻohana lōʻihi ʻana i ka estrogen i nā nui kiʻekiʻe. ʻO nā kumu nui no kēia:

• ʻO ka lāʻau hoʻololi hormone (HRT) no ka menopause.
• ʻO ke kiʻekiʻe maoli o ka estrogen i loko o ke kino.
• ʻO ka maʻi Klinefelter kahi maʻi genetic e hoʻopilikia ai i nā kāne (he kiʻekiʻe nā pae estrogen o nā kāne me kēia maʻi).

I ka wā ma mua, ua hāʻawi ʻia kekahi mau kāne i ka hormone estrogen ma ke ʻano he lāʻau lapaʻau no ke kanesa prostate. Akā i kēia manawa, ʻaʻole pinepine nā kauka e ʻōlelo i kēlā lāʻau lapaʻau no ka mea hoʻonui pū ia i ka pilikia o ka maʻi kanesa umauma i nā kāne.

He aha ka pilina ma waena o ka estrogen a me ke kanesa ovarian?

ʻO ka hōʻike ʻana i ka estrogen i ke ola holoʻokoʻa e hiki ke hoʻonui i ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai ovarian. ʻO nā kumu pilikia:

• Hoʻomaka ka menstruation ma mua o ka piha ʻana o 12 mau makahiki (ʻo ia hoʻi ka wā ʻōpiopio mua).
• ʻAʻole loa e hāpai.
• Ke loaʻa nei ka menopause (ʻo ia hoʻi ke loaʻa ʻana o nā menstruations no kahi manawa lōʻihi) ma hope o 55 mau makahiki.
• ʻO ka lawe ʻana i ka hui pū ʻana o ka hormone therapy (hormone therapy) ma hope o ka menopause, nona ka estrogen a me ka progesterone.

He aha ka pilina ma waena o ka estrogen a me ke kanesa o ka ʻōpū?

ʻO ke kanesa ʻōpū, a i ʻole e like me kā mākou i ʻōlelo ai ma mua, ʻo ke kanesa endometrial, e ulu ana i loko o ka uhi o kou uterus . ʻOi aku ka nui o ka loaʻa ʻana o kēia maʻi kanesa i nā wahine ma hope o ka menopause.

Hiki ke hoʻonui ʻia ka pilikia o ka estrogen e nā kumu e like me:

• Lapaʻau hoʻololi Estrogen: Kōkua ʻo Estrogen i ka hōʻemi ʻana i nā ʻehaʻeha o ka menopause, e like me nā ʻālohilohi wela, ka hou ʻana i ka pō, a me ka maloʻo o ka ʻōpū. Eia nō naʻe, ʻo ka lawe ʻana i ka lāʻau estrogen-wale nō e hoʻonui i ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai uterine. ʻO kēia no ka mea hoʻoulu ka estrogen i ka ulu ʻana o ka uhi o ka uterus. ʻO ia ke kumu e hāʻawi pinepine ʻia ai ka estrogen me kahi hormone i kapa ʻia ʻo progesterone (hui pū ʻana o ka hormone therapy). Hoʻemi kēia i ka pilikia o ka maʻi ʻaʻai uterine. Eia nō naʻe, inā ua loaʻa iā ʻoe kahi hysterectomy, ʻaʻole ʻoe e loaʻa i kēia maʻi ʻaʻai no ka mea ʻaʻohe ou uterus.
• Nā Hoʻohana ʻana o Tamoxifen: He lāʻau koʻikoʻi loa ʻo Tamoxifen i hoʻohana ʻia no ka mālama ʻana i ka maʻi ʻaʻai umauma a pale i ka hoʻi hou ʻana mai o ke kanesa. Hana ia ma ke ʻano he Selective Estrogen Receptor Modulator (SERM) a ālai i nā hopena o ka estrogen ma nā ʻiʻo umauma. Eia nō naʻe, i nā wahine postmenopausal, hana ʻo tamoxifen e like me ka estrogen i loko o ka ʻōpū. Hoʻoulu kēia i ka ulu ʻana o ka uhi o ka ʻōpū, kahi e hoʻonui ai i ka pilikia o ka maʻi ʻaʻai endometrial i kekahi ʻano. Akā, mai hopohopo, ʻo ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai endometrial ma muli o tamoxifen he emi ma mua o 1% i kēlā me kēia makahiki. Aia kekahi pilikia liʻiliʻi loa o ka loaʻa ʻana o ka sarcoma uterine, kahi ʻano maʻi ʻaʻai kakaikahi e ulu ana i loko o nā ʻiʻo a i ʻole nā ​​​​ʻiʻo ʻē aʻe o ka ʻōpū.

Pehea e ʻike ʻia ai nā maʻi ʻaʻai e pili ana i ka estrogen? Pehea e ʻike ai nā kauka i kēia?

Inā kānalua ʻoe he maʻi kanesa kou, ʻo ka mea mua a kāu kauka e hana ai, ʻo ia ke lawe i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai ka puʻupuʻu (kapa mākou i kēia he biopsy puʻupuʻu) a hoʻouna aku i kahi keʻena hoʻokolohua. Ma laila, e hoʻohana lākou i nā hoʻokolohua kūikawā e nānā inā loaʻa i kēlā mau cell nā mea loaʻa hormone.

Inā hoʻi mai ka hopena o ka hoʻāʻo ma ke ʻano he hormone receptor positive (HR+) , ʻo ia hoʻi ke kōkua nei ka estrogen, progesterone, a i ʻole kēia mau hormones ʻelua i ka ulu ʻana o kāu maʻi kanesa, ʻo ia hoʻi, ka hānai ʻana iā ia.

Pehea e mālama ʻia ai nā maʻi ʻaʻai e pili ana i ka estrogen e like me kēia?

He mea nui i nā kauka ke ʻike i ke kūlana o ka mea loaʻa hormone o kahi maʻi kanesa, ʻoiai ʻo kekahi mau lāʻau lapaʻau he kūpono wale nō ia no nā maʻi kanesa hormone-positive. ʻO kekahi o nā lāʻau lapaʻau nui no kēia ʻano maʻi kanesa:

• Nā mea hoʻopaʻa aromatase: Hana kēia mau lāʻau lapaʻau ma ka pale ʻana i ke kino mai ka hoʻololi ʻana i nā androgens, kahi hormone, i estrogen. He kūpono wale nō kēia lāʻau lapaʻau i nā wahine i hala i ka menopause (ʻo ia hoʻi, ua pau ka hana ʻana o kā lākou ovaries i ka estrogen).
• Nā lāʻau lapaʻau hormone ʻē aʻe: Hoʻemi a hoʻōki paha kēia i ka hana ʻana o ke kino i ka estrogen.
• ʻO Tamoxifen a me nā lāʻau SERM ʻē aʻe: E like me kā mākou i kūkākūkā ai ma mua, hana kēia mau mea ma ke ālai ʻana i nā mea loaʻa hormone mai ka hoʻopaʻa ʻana i ka estrogen.
• ʻO ka ʻoki ʻana: I kekahi mau hihia, ua wehe ʻia nā ovaries, nā ʻōkana nui e hana ana i ka estrogen, ma ke ʻoki ʻana. Hiki i kēia ke hōʻemi nui i nā pae estrogen i loko o ke kino.

Hiki i nā lāʻau hoʻomalu hānau ke hōʻemi maoli i ka pilikia o kēia maʻi kanesa?

Hiki i ka pane i kēia ke ʻae a me ka ʻaʻole. Pehea lā ia?

Ua hōʻike kekahi mau noiʻi e hiki i nā wāhine e hoʻohana ana i nā ʻano hana kaohi hānau hormonal, e like me ka pila, ke loaʻa i kahi liʻiliʻi loa (ma kahi o 7%) ka piʻi ʻana o ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai umauma .

Eia nō naʻe, ma ka ʻaoʻao ʻē aʻe, ʻo ka lawe ʻana i nā pila hoʻomalu hānau e hōʻemi paha i ka pilikia o ka hoʻomohala ʻana i nā ʻano maʻi kanesa penei:

• Ka maʻi ʻaʻai o ka ʻōpū
• Ka maʻi ʻaʻai colorectal
• Ka maʻi ʻōpū
• Ka maʻi ʻōpū

No laila, e like me kāu e ʻike ai, he mea paʻakikī iki kēia. No laila, ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka a hoʻoholo i ke ʻano o ka hoʻomalu hānau ʻana i kūpono loa iā ʻoe, a ʻo wai ka mea palekana loa.

He aha kā mākou e hana ai e pale aku i ka ulu ʻana o ka maʻi kanesa e pili ana i ka estrogen?

Hoʻomohala ka hapa nui o nā maʻi kanesa me ke kumu ʻole. ʻO ke ʻano kēia, i kekahi manawa hiki ke ulu ka maʻi kanesa me ka nānā ʻole i ke akahele o kākou. Eia nō naʻe, aia kekahi mau mea maʻalahi hiki iā kākou ke hana e hōʻemi i ka pilikia o ka maʻi kanesa i kekahi ʻano.

• Inā hiki, e hānai i kāu mau keiki me ka waiū umauma. Ua ʻike ʻia ka hānai ʻana i ka waiū umauma e hōʻemi i ka pilikia o ka maʻi ʻaʻai umauma.
• E hōʻemi i ka inu ʻana i ka waiʻona i ka hiki a pale loa i ka puhipaka. ʻO kēia nā mea e kōkua ai i nā maʻi kanesa he nui.
• E hoʻāʻo e ʻai i ka meaʻai olakino. E ʻai i nā mea kanu a me nā huaʻai hou aku. Eia kekahi, e hoʻoikaika kino i kēlā me kēia lā a e hana kino.
• Inā ʻoe he momona loa, ʻo ia hoʻi, momona, e hoʻāʻo e hoʻemi i ke kaumaha.
• E kamaʻilio me kāu kauka e pili ana i ke ʻano kaohi hānau palekana loa nāu.
• Inā makemake ʻoe e hoʻokele i nā ʻehaʻeha o ka menopause, e ʻimi i ka ʻōlelo aʻoaʻo lapaʻau e pili ana i ka hui pū ʻana o ka hormone therapy a i ʻole nā ​​​​lāʻau lapaʻau nonhormonal.

He aha nā nīnau koʻikoʻi e pono iaʻu e nīnau aku i kaʻu kauka?

Inā he mau hopohopo kou e pili ana i kēia maʻi, a i ʻole e pili ana i ka pilikia o ka maʻi kanesa e pili ana i ka estrogen, mai kānalua e nīnau i kāu kauka. He mea nui e hoʻopau i kou kānalua. Eia kekahi mau nīnau hiki iā ʻoe ke nīnau:

• He hilinaʻi anei koʻu maʻi kanesa i ka estrogen a i ʻole he hormone-receptor-positive?
• He aha nā lāʻau lapaʻau maikaʻi loa i loaʻa i kēia manawa no kēia ʻano maʻi kanesa?
• He aha nā pilikia a me nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau?
• He aha nā hoʻololi e hiki iaʻu ke hana i koʻu nohona e pale ai i koʻu olakino a hōʻemi i koʻu pilikia o ka maʻi kanesa?
• Pono anei au e hoʻololi i ke ʻano hana hoʻomalu hānau aʻu e hoʻohana nei i kēia manawa? He aha ke ʻano hana maikaʻi loa iaʻu?
• He kūpono anei iaʻu ke lawe i ka lāʻau lapaʻau hormone? Aia kekahi mau pilikia noʻu?

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

I ka hapa nui o ka manawa, he kuleana maikaʻi ko ka hormone estrogen i loko o ko kākou kino, e kōkua ana iā lākou e hana olakino. Eia nō naʻe, he ʻokoʻa nā maʻi kanesa e hilinaʻi ana i ka estrogen. I loko o kēia mau maʻi kanesa kikoʻī, kōkua maoli ka estrogen i ka ulu ʻana o ke kanesa, ʻo ia hoʻi, hānai ia i ke kanesa.

Inā ua ʻike ʻia ʻoe he maʻi kanesa a ke manaʻo nei kāu kauka he mea pili paha ia i ka hormone, e hana maoli lākou i nā hoʻokolohua e pono ai e ʻike inā pili ia i ka estrogen. Ma muli o kēlā ʻike, hiki i kāu kauka ke koho i ka lāʻau lapaʻau kūpono loa a kūpono hoʻi nāu.

No laila, me ka makaʻu ʻole a me ka hoʻopaʻa ʻole ʻana i kekahi mea, e kūkākūkā ākea i kāu mau nīnau a me nā kānalua me kāu kauka. He mea nui loa ia no kou olakino a me kou noʻonoʻo pono.

ʻEstrogen , maʻi ʻaʻai, hormones, maʻi ʻaʻai umauma, maʻi ʻaʻai ovarian, maʻi ʻaʻai uterine, olakino wahine